DE602006011360D1 - Katalysiertes verfahren zur herstellung von c-5-substituierten heterocyclischen inhibitoren von 11beta-hydroxysteroiddehydrogenase vom typ 1 - Google Patents
Katalysiertes verfahren zur herstellung von c-5-substituierten heterocyclischen inhibitoren von 11beta-hydroxysteroiddehydrogenase vom typ 1Info
- Publication number
- DE602006011360D1 DE602006011360D1 DE602006011360T DE602006011360T DE602006011360D1 DE 602006011360 D1 DE602006011360 D1 DE 602006011360D1 DE 602006011360 T DE602006011360 T DE 602006011360T DE 602006011360 T DE602006011360 T DE 602006011360T DE 602006011360 D1 DE602006011360 D1 DE 602006011360D1
- Authority
- DE
- Germany
- Prior art keywords
- hydroxysteroiddehydrogenase
- 11beta
- preparation
- type
- substituted heterocyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/54—Nitrogen and either oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73857405P | 2005-11-22 | 2005-11-22 | |
| PCT/US2006/042913 WO2007061600A1 (en) | 2005-11-22 | 2006-11-01 | CATALYZED PROCESS OF MAKING C-5-SUBSTITUTED HETEROCYCLIC INHIBITORS OF 11ß-HYDROXY STEROID DEHYDROGENASE TYPE 1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602006011360D1 true DE602006011360D1 (de) | 2010-02-04 |
Family
ID=37882184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602006011360T Active DE602006011360D1 (de) | 2005-11-22 | 2006-11-01 | Katalysiertes verfahren zur herstellung von c-5-substituierten heterocyclischen inhibitoren von 11beta-hydroxysteroiddehydrogenase vom typ 1 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7541474B2 (de) |
| EP (1) | EP1951695B1 (de) |
| AT (1) | ATE452881T1 (de) |
| AU (1) | AU2006317070B2 (de) |
| CA (1) | CA2630558A1 (de) |
| DE (1) | DE602006011360D1 (de) |
| ES (1) | ES2335141T3 (de) |
| WO (1) | WO2007061600A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2335141T3 (es) | 2005-11-22 | 2010-03-22 | Amgen Inc. | Procedimiento catalizado para hacer inhibidores heterociclicos sustituidos en c-5 de la 11-beta-hidroxiesteroide deshidrogenasa de tipo 1. |
| JP5411850B2 (ja) * | 2007-06-21 | 2014-02-12 | アムジエン・インコーポレーテツド | 置換２−アミノ−チアゾロンを作製するための方法 |
| ES2386613T3 (es) * | 2008-07-29 | 2012-08-23 | Amgen, Inc | Procedimiento asimétrico para preparar 2-amino-tiazolonas sustituidas |
| WO2012051139A1 (en) | 2010-10-15 | 2012-04-19 | Amgen Inc. | New uses for substituted 2-amino-thiazolones in treating alzheimer's disease |
| CA3017740A1 (en) | 2016-03-16 | 2017-09-21 | Pearlie BURNETTE | Small molecules against cereblon to enhance effector t cell function |
| PE20210184A1 (es) | 2018-07-11 | 2021-02-02 | H Lee Moffitt Cancer Ct & Res | Compuestos inmunomoduladores dimericos contra mecanismos basados en cereblon |
| CN108976170B (zh) * | 2018-08-14 | 2022-04-22 | 华南理工大学 | 一种5-三氟甲基-4h-咪唑啉-4-酮衍生物及合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE417837T1 (de) * | 2004-05-24 | 2009-01-15 | Amgen Inc | Inhibitoren von 11-beta- hydroxysteroiddehydrogenase typ 1 |
| ES2335141T3 (es) | 2005-11-22 | 2010-03-22 | Amgen Inc. | Procedimiento catalizado para hacer inhibidores heterociclicos sustituidos en c-5 de la 11-beta-hidroxiesteroide deshidrogenasa de tipo 1. |
-
2006
- 2006-11-01 ES ES06827425T patent/ES2335141T3/es active Active
- 2006-11-01 AU AU2006317070A patent/AU2006317070B2/en not_active Ceased
- 2006-11-01 EP EP06827425A patent/EP1951695B1/de active Active
- 2006-11-01 AT AT06827425T patent/ATE452881T1/de not_active IP Right Cessation
- 2006-11-01 US US11/590,922 patent/US7541474B2/en not_active Expired - Fee Related
- 2006-11-01 DE DE602006011360T patent/DE602006011360D1/de active Active
- 2006-11-01 CA CA002630558A patent/CA2630558A1/en not_active Abandoned
- 2006-11-01 WO PCT/US2006/042913 patent/WO2007061600A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| ES2335141T3 (es) | 2010-03-22 |
| US7541474B2 (en) | 2009-06-02 |
| AU2006317070A1 (en) | 2007-05-31 |
| EP1951695A1 (de) | 2008-08-06 |
| US20070117985A1 (en) | 2007-05-24 |
| AU2006317070B2 (en) | 2011-06-23 |
| ATE452881T1 (de) | 2010-01-15 |
| WO2007061600A1 (en) | 2007-05-31 |
| EP1951695B1 (de) | 2009-12-23 |
| CA2630558A1 (en) | 2007-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |