ATE383325T1 - Verfahren zur herstellung von optisch aktivem alkohol in gegenwart von rhodium, einem chiralen ferrocenyldiphosphin und einem optisch aktivem diamin - Google Patents

Verfahren zur herstellung von optisch aktivem alkohol in gegenwart von rhodium, einem chiralen ferrocenyldiphosphin und einem optisch aktivem diamin

Info

Publication number
ATE383325T1
ATE383325T1 AT04717253T AT04717253T ATE383325T1 AT E383325 T1 ATE383325 T1 AT E383325T1 AT 04717253 T AT04717253 T AT 04717253T AT 04717253 T AT04717253 T AT 04717253T AT E383325 T1 ATE383325 T1 AT E383325T1
Authority
AT
Austria
Prior art keywords
optically active
rhodium
ferrocenyldiphospine
chiral
diamine
Prior art date
Application number
AT04717253T
Other languages
English (en)
Inventor
Toyofumi Ito
Tsuyoshi Aoki
Original Assignee
Kawaken Fine Chemicals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kawaken Fine Chemicals Co filed Critical Kawaken Fine Chemicals Co
Application granted granted Critical
Publication of ATE383325T1 publication Critical patent/ATE383325T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00Asymmetric syntheses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C07C29/145Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
AT04717253T 2003-03-07 2004-03-04 Verfahren zur herstellung von optisch aktivem alkohol in gegenwart von rhodium, einem chiralen ferrocenyldiphosphin und einem optisch aktivem diamin ATE383325T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003061843 2003-03-07

Publications (1)

Publication Number Publication Date
ATE383325T1 true ATE383325T1 (de) 2008-01-15

Family

ID=32958977

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04717253T ATE383325T1 (de) 2003-03-07 2004-03-04 Verfahren zur herstellung von optisch aktivem alkohol in gegenwart von rhodium, einem chiralen ferrocenyldiphosphin und einem optisch aktivem diamin

Country Status (4)

Country Link
EP (1) EP1601635B1 (de)
AT (1) ATE383325T1 (de)
DE (1) DE602004011193D1 (de)
WO (1) WO2004078686A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4490211B2 (ja) * 2004-08-27 2010-06-23 高砂香料工業株式会社 光学活性3−キヌクリジノール類の製造方法
JP5172124B2 (ja) 2006-09-29 2013-03-27 関東化学株式会社 2位に置換基を有する光学活性キヌクリジノール類の製造方法
DE102009030291A1 (de) * 2009-06-24 2011-01-05 Cu Chemie Uetikon Gmbh Enantiomerenreine tricyclische Verbindung und Verfahren zur diastereomerenreinen und enantiomerenreinen Herstellung bicyclischer und tricyclischer Verbindungen
US10526287B2 (en) 2015-04-23 2020-01-07 Constellation Pharmaceuticals, Inc. LSD1 inhibitors and uses thereof
WO2018081343A1 (en) 2016-10-26 2018-05-03 Constellation Pharmaceuticals, Inc. Lsd1 inhibitors and medical uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE194342T1 (de) * 1996-01-19 2000-07-15 Lonza Ag Verfahren zur herstellung von optisch aktivem 3- chinuclidinol

Also Published As

Publication number Publication date
DE602004011193D1 (de) 2008-02-21
EP1601635B1 (de) 2008-01-09
WO2004078686A1 (en) 2004-09-16
EP1601635A1 (de) 2005-12-07

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