ATE371641T1 - Hydroxy-tetrahydro-naphtalenylharnstoff-derivat - Google Patents
Hydroxy-tetrahydro-naphtalenylharnstoff-derivatInfo
- Publication number
- ATE371641T1 ATE371641T1 AT03722554T AT03722554T ATE371641T1 AT E371641 T1 ATE371641 T1 AT E371641T1 AT 03722554 T AT03722554 T AT 03722554T AT 03722554 T AT03722554 T AT 03722554T AT E371641 T1 ATE371641 T1 AT E371641T1
- Authority
- AT
- Austria
- Prior art keywords
- tetrahydro
- pain
- naphtalenyl
- hydroxy
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0210512.0A GB0210512D0 (en) | 2002-05-08 | 2002-05-08 | Tetrahydro-napthalene derivatives |
| GBGB0227262.3A GB0227262D0 (en) | 2002-05-08 | 2002-11-21 | Tetrahydro-naphthalene derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE371641T1 true ATE371641T1 (de) | 2007-09-15 |
Family
ID=29422108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03722554T ATE371641T1 (de) | 2002-05-08 | 2003-04-28 | Hydroxy-tetrahydro-naphtalenylharnstoff-derivat |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7612113B2 (de) |
| EP (1) | EP1506167B1 (de) |
| JP (1) | JP4335131B2 (de) |
| CN (1) | CN1307150C (de) |
| AT (1) | ATE371641T1 (de) |
| AU (1) | AU2003229734B2 (de) |
| BR (1) | BR0309940A (de) |
| CA (1) | CA2487238C (de) |
| DE (1) | DE60315973T2 (de) |
| DK (1) | DK1506167T3 (de) |
| ES (1) | ES2292959T3 (de) |
| HK (1) | HK1082946A1 (de) |
| HR (1) | HRP20041167A2 (de) |
| IL (1) | IL165004A (de) |
| MX (1) | MXPA04010938A (de) |
| NO (1) | NO20045359L (de) |
| NZ (1) | NZ536418A (de) |
| PL (1) | PL210288B1 (de) |
| RU (1) | RU2331635C2 (de) |
| TW (1) | TWI271396B (de) |
| WO (1) | WO2003095420A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004028440A2 (en) * | 2002-09-24 | 2004-04-08 | Bayer Healthcare Ag | Vr1 antagonists for the treatment of urological disorders |
| US7381840B2 (en) | 2002-12-06 | 2008-06-03 | Xention Limited | Tetrahydro-naphthalene derivatives |
| DK1572632T3 (da) * | 2002-12-09 | 2008-10-27 | Xention Ltd | Tetrahydro-naphthalenderivater som vanilloidreceptorantagonister |
| WO2005035471A1 (ja) | 2003-10-14 | 2005-04-21 | Ajinomoto Co., Inc. | エーテル誘導体 |
| CA2542494A1 (en) * | 2003-10-15 | 2005-05-06 | Bayer Healthcare Ag | Tetrahydro-naphthalene and urea derivatives |
| WO2005044802A2 (en) * | 2003-11-08 | 2005-05-19 | Bayer Healthcare Ag | Tetrahydro-quinolinylurea derivatives as vrl antagonists |
| WO2005095329A1 (en) * | 2004-03-31 | 2005-10-13 | Pfizer Japan Inc. | Substituted benzamide compounds as vr1 receptor antagonists |
| CA2599778A1 (en) * | 2005-03-05 | 2006-09-14 | Bayer Healthcare Ag | Use of hydroxy tetrahydro-naphtalene derivates for the treatment of respiratory diseases |
| EA200702020A1 (ru) | 2005-03-19 | 2008-02-28 | Эморпасифик Корпорейшн | Новые соединения, их изомеры или фармацевтически приемлемые соли в качестве антагонистов ваниллоидных рецепторов и содержащие их фармацевтические композиции |
| DE102005017286B3 (de) * | 2005-04-14 | 2006-12-28 | Schering Ag | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| DE102005023943A1 (de) | 2005-05-20 | 2006-11-23 | Grünenthal GmbH | Pentafluorsulfanyl-substituierte Verbindung und deren Verwendung zur Herstellung von Arzneimitteln |
| EP2134678A2 (de) | 2006-12-20 | 2009-12-23 | Abbott Laboratories | N-(5,6,7,8-tetrahydronaphthalin-1-yl)harnstoffderivate und verwandte verbindungen als antagonisten des trpv1-vanilloidrezeptors zur behandlung von schmerzen |
| WO2008096755A1 (ja) * | 2007-02-07 | 2008-08-14 | Nippon Suisan Kaisha, Ltd. | バニロイド受容体（ｖｒ１）阻害剤及びその用途 |
| DE102009055915A1 (de) * | 2009-11-27 | 2011-06-01 | Beiersdorf Ag | Verwendung von Zingeron zur Herstellung kosmetischer oder dermatologischer Zubereitungen, welche auf der Haut ein Prickeln hervorrufen |
| EP4019485B1 (de) | 2019-08-23 | 2024-08-07 | Mochida Pharmaceutical Co., Ltd. | Verfahren zur herstellung von heterocyclidenacetamidderivaten |
| EP4410989A2 (de) | 2019-08-23 | 2024-08-07 | Mochida Pharmaceutical Co., Ltd. | Verfahren zur herstellung von heterocyclidenacetamid-derivaten |
| DE102022104759A1 (de) | 2022-02-28 | 2023-08-31 | SCi Kontor GmbH | Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9713484D0 (en) | 1997-06-27 | 1997-09-03 | Smithkline Beecham Plc | Neuroprotective vanilloid compounds |
| US6333337B1 (en) * | 1998-01-27 | 2001-12-25 | Icagen, Inc. | Potassium channel inhibitors |
| US6476076B1 (en) | 1999-02-22 | 2002-11-05 | Pacific Corporation | Vanilloid analogues containing resinferatoxin pharmacophores as potent vanilloid receptor agonists and analgesics, compositions and uses thereof |
| NZ514662A (en) | 1999-04-07 | 2004-01-30 | Sankyo Co | Amine derivatives |
| US6294694B1 (en) | 1999-06-04 | 2001-09-25 | Wisconsin Alumni Research Foundation | Matrix metalloproteinase inhibitors and method of using same |
| US7381840B2 (en) * | 2002-12-06 | 2008-06-03 | Xention Limited | Tetrahydro-naphthalene derivatives |
| EP1493438A1 (de) * | 2003-07-03 | 2005-01-05 | Bayer HealthCare AG | Inhibitoren des Vanilloid-Rezeptors (VR1) zur Behandlung von HIV-bedingten Schmerz |
| CA2542494A1 (en) * | 2003-10-15 | 2005-05-06 | Bayer Healthcare Ag | Tetrahydro-naphthalene and urea derivatives |
| ES2315716T3 (es) * | 2003-11-08 | 2009-04-01 | Bayer Healthcare Ag | Derivados de amida, carbamato o urea biciclica como moduladores del receptor vanilloide. |
-
2003
- 2003-04-28 BR BR0309940-7A patent/BR0309940A/pt not_active IP Right Cessation
- 2003-04-28 DK DK03722554T patent/DK1506167T3/da active
- 2003-04-28 CA CA2487238A patent/CA2487238C/en not_active Expired - Lifetime
- 2003-04-28 NZ NZ536418A patent/NZ536418A/en not_active IP Right Cessation
- 2003-04-28 US US10/513,848 patent/US7612113B2/en active Active
- 2003-04-28 PL PL373257A patent/PL210288B1/pl unknown
- 2003-04-28 CN CNB038159880A patent/CN1307150C/zh not_active Expired - Lifetime
- 2003-04-28 ES ES03722554T patent/ES2292959T3/es not_active Expired - Lifetime
- 2003-04-28 AU AU2003229734A patent/AU2003229734B2/en not_active Expired
- 2003-04-28 WO PCT/EP2003/004395 patent/WO2003095420A1/en active IP Right Grant
- 2003-04-28 AT AT03722554T patent/ATE371641T1/de active
- 2003-04-28 MX MXPA04010938A patent/MXPA04010938A/es active IP Right Grant
- 2003-04-28 DE DE60315973T patent/DE60315973T2/de not_active Expired - Lifetime
- 2003-04-28 EP EP03722554A patent/EP1506167B1/de not_active Expired - Lifetime
- 2003-04-28 RU RU2004136281/04A patent/RU2331635C2/ru not_active IP Right Cessation
- 2003-04-28 JP JP2004503441A patent/JP4335131B2/ja not_active Expired - Lifetime
- 2003-05-07 TW TW092112380A patent/TWI271396B/zh not_active IP Right Cessation
-
2004
- 2004-11-03 IL IL165004A patent/IL165004A/en not_active IP Right Cessation
- 2004-12-07 HR HR20041167A patent/HRP20041167A2/xx not_active Application Discontinuation
- 2004-12-07 NO NO20045359A patent/NO20045359L/no not_active Application Discontinuation
-
2006
- 2006-03-02 HK HK06102754A patent/HK1082946A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1307150C (zh) | 2007-03-28 |
| JP2005524717A (ja) | 2005-08-18 |
| IL165004A (en) | 2010-12-30 |
| AU2003229734A1 (en) | 2003-11-11 |
| CA2487238A1 (en) | 2003-11-20 |
| RU2004136281A (ru) | 2005-07-10 |
| PL373257A1 (en) | 2005-08-22 |
| ES2292959T3 (es) | 2008-03-16 |
| MXPA04010938A (es) | 2005-02-14 |
| CA2487238C (en) | 2011-03-22 |
| HRP20041167A2 (en) | 2005-08-31 |
| RU2331635C2 (ru) | 2008-08-20 |
| WO2003095420A1 (en) | 2003-11-20 |
| JP4335131B2 (ja) | 2009-09-30 |
| US20060258742A1 (en) | 2006-11-16 |
| BR0309940A (pt) | 2005-02-09 |
| TW200404052A (en) | 2004-03-16 |
| DE60315973D1 (de) | 2007-10-11 |
| DK1506167T3 (da) | 2008-01-02 |
| AU2003229734B2 (en) | 2009-02-19 |
| IL165004A0 (en) | 2005-12-18 |
| EP1506167B1 (de) | 2007-08-29 |
| CN1665778A (zh) | 2005-09-07 |
| NZ536418A (en) | 2006-04-28 |
| EP1506167A1 (de) | 2005-02-16 |
| DE60315973T2 (de) | 2008-05-21 |
| NO20045359L (no) | 2004-12-07 |
| PL210288B1 (pl) | 2011-12-30 |
| TWI271396B (en) | 2007-01-21 |
| US7612113B2 (en) | 2009-11-03 |
| HK1082946A1 (en) | 2006-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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