NO20045359L - Hydroksy-tetrahydro-naftalenylureaderivater - Google Patents
Hydroksy-tetrahydro-naftalenylureaderivaterInfo
- Publication number
- NO20045359L NO20045359L NO20045359A NO20045359A NO20045359L NO 20045359 L NO20045359 L NO 20045359L NO 20045359 A NO20045359 A NO 20045359A NO 20045359 A NO20045359 A NO 20045359A NO 20045359 L NO20045359 L NO 20045359L
- Authority
- NO
- Norway
- Prior art keywords
- tetrahydro
- pain
- useful
- treatment
- naphthalene derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Foreliggende oppfinnelse angår tefrahydro-naftalenderivater og salter derav som er anvendehge som aktive ingredienser i farmasøytiske preparater. Tefrahydro-naftalenderivatene ifølge oppfmnelsen har en svært god aktivitet som VRI antagonist og anvendelig for profylakse og behandling av sykdorrmier assosiert med VRI aktivitet, særlig for behandling av frengende urininkontinens, overaktiv blære, kronisk smerte, neuropatisk smerte, postoperativ smerte, reumatoid artrittsmerte, neuralgi, neuropati, algesi, nerveskade, ishemi, neurodegenerasjon, slag, inkontinens, inflammasjonsforstyrrelser slike som astina og eOPD.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0210512.0A GB0210512D0 (en) | 2002-05-08 | 2002-05-08 | Tetrahydro-napthalene derivatives |
GBGB0227262.3A GB0227262D0 (en) | 2002-05-08 | 2002-11-21 | Tetrahydro-naphthalene derivatives |
PCT/EP2003/004395 WO2003095420A1 (en) | 2002-05-08 | 2003-04-28 | Hydroxy tetrahydro-naphthalenylurea derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20045359L true NO20045359L (no) | 2004-12-07 |
Family
ID=29422108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20045359A NO20045359L (no) | 2002-05-08 | 2004-12-07 | Hydroksy-tetrahydro-naftalenylureaderivater |
Country Status (21)
Country | Link |
---|---|
US (1) | US7612113B2 (no) |
EP (1) | EP1506167B1 (no) |
JP (1) | JP4335131B2 (no) |
CN (1) | CN1307150C (no) |
AT (1) | ATE371641T1 (no) |
AU (1) | AU2003229734B2 (no) |
BR (1) | BR0309940A (no) |
CA (1) | CA2487238C (no) |
DE (1) | DE60315973T2 (no) |
DK (1) | DK1506167T3 (no) |
ES (1) | ES2292959T3 (no) |
HK (1) | HK1082946A1 (no) |
HR (1) | HRP20041167A2 (no) |
IL (1) | IL165004A (no) |
MX (1) | MXPA04010938A (no) |
NO (1) | NO20045359L (no) |
NZ (1) | NZ536418A (no) |
PL (1) | PL210288B1 (no) |
RU (1) | RU2331635C2 (no) |
TW (1) | TWI271396B (no) |
WO (1) | WO2003095420A1 (no) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004028440A2 (en) * | 2002-09-24 | 2004-04-08 | Bayer Healthcare Ag | Vr1 antagonists for the treatment of urological disorders |
WO2004052846A1 (en) | 2002-12-06 | 2004-06-24 | Bayer Healthcare Ag | Tetrahydro-naphthalene derivatives |
JP4440113B2 (ja) * | 2002-12-09 | 2010-03-24 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | バニロイド受容体アンタゴニストとしてのテトラヒドロ−ナフタレン誘導体 |
WO2005035471A1 (ja) | 2003-10-14 | 2005-04-21 | Ajinomoto Co., Inc. | エーテル誘導体 |
CA2542494A1 (en) * | 2003-10-15 | 2005-05-06 | Bayer Healthcare Ag | Tetrahydro-naphthalene and urea derivatives |
CA2545109A1 (en) * | 2003-11-08 | 2005-05-19 | Bayer Healthcare Ag | Tetrahydro-quinolinylurea derivatives |
WO2005095329A1 (en) * | 2004-03-31 | 2005-10-13 | Pfizer Japan Inc. | Substituted benzamide compounds as vr1 receptor antagonists |
JP2008532956A (ja) * | 2005-03-05 | 2008-08-21 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | ヒドロキシテトラヒドロ−ナフタレン誘導体の使用 |
EP1861357B1 (en) | 2005-03-19 | 2013-04-24 | Amorepacific Corporation | Novel compounds or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same |
DE102005017286B3 (de) * | 2005-04-14 | 2006-12-28 | Schering Ag | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
DE102005023943A1 (de) | 2005-05-20 | 2006-11-23 | Grünenthal GmbH | Pentafluorsulfanyl-substituierte Verbindung und deren Verwendung zur Herstellung von Arzneimitteln |
EP2450346A1 (en) | 2006-12-20 | 2012-05-09 | Abbott Laboratories | Antagonists of the TRPV1 receptor and uses thereof |
WO2008096755A1 (ja) * | 2007-02-07 | 2008-08-14 | Nippon Suisan Kaisha, Ltd. | バニロイド受容体(vr1)阻害剤及びその用途 |
DE102009055915A1 (de) * | 2009-11-27 | 2011-06-01 | Beiersdorf Ag | Verwendung von Zingeron zur Herstellung kosmetischer oder dermatologischer Zubereitungen, welche auf der Haut ein Prickeln hervorrufen |
JP6830569B1 (ja) | 2019-08-23 | 2021-02-17 | 持田製薬株式会社 | ヘテロシクリデンアセトアミド誘導体の製造方法 |
WO2021039023A1 (ja) | 2019-08-23 | 2021-03-04 | 持田製薬株式会社 | ヘテロシクリデンアセトアミド誘導体の製造方法 |
DE102022104759A1 (de) | 2022-02-28 | 2023-08-31 | SCi Kontor GmbH | Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9713484D0 (en) | 1997-06-27 | 1997-09-03 | Smithkline Beecham Plc | Neuroprotective vanilloid compounds |
US6333337B1 (en) * | 1998-01-27 | 2001-12-25 | Icagen, Inc. | Potassium channel inhibitors |
ES2253208T3 (es) * | 1999-02-22 | 2006-06-01 | Pacific Corporation | Analogos de vaniloide que contienen farmacoforos de resiniferatoxina como ponentes agonistas del receptor de vaniloide y analgesicos, composiciones y utilizaciones de los mismos. |
AU757729B2 (en) | 1999-04-07 | 2003-03-06 | Sankyo Company Limited | Amine derivatives |
US6294694B1 (en) | 1999-06-04 | 2001-09-25 | Wisconsin Alumni Research Foundation | Matrix metalloproteinase inhibitors and method of using same |
WO2004052846A1 (en) * | 2002-12-06 | 2004-06-24 | Bayer Healthcare Ag | Tetrahydro-naphthalene derivatives |
EP1493438A1 (en) * | 2003-07-03 | 2005-01-05 | Bayer HealthCare AG | Vanilloid receptor (VR) inhibitors for treatment of Human Immunodeficiency Virus (HIV)-mediated pain states |
CA2542494A1 (en) * | 2003-10-15 | 2005-05-06 | Bayer Healthcare Ag | Tetrahydro-naphthalene and urea derivatives |
CA2545100A1 (en) * | 2003-11-08 | 2005-05-19 | Bayer Healthcare Ag | Bicyclic amide, carbamate or urea derivatives as vanilloid receptor modulators |
-
2003
- 2003-04-28 WO PCT/EP2003/004395 patent/WO2003095420A1/en active IP Right Grant
- 2003-04-28 PL PL373257A patent/PL210288B1/pl unknown
- 2003-04-28 NZ NZ536418A patent/NZ536418A/en not_active IP Right Cessation
- 2003-04-28 RU RU2004136281/04A patent/RU2331635C2/ru not_active IP Right Cessation
- 2003-04-28 DE DE60315973T patent/DE60315973T2/de not_active Expired - Lifetime
- 2003-04-28 EP EP03722554A patent/EP1506167B1/en not_active Expired - Lifetime
- 2003-04-28 JP JP2004503441A patent/JP4335131B2/ja not_active Expired - Lifetime
- 2003-04-28 MX MXPA04010938A patent/MXPA04010938A/es active IP Right Grant
- 2003-04-28 CN CNB038159880A patent/CN1307150C/zh not_active Expired - Lifetime
- 2003-04-28 AT AT03722554T patent/ATE371641T1/de active
- 2003-04-28 US US10/513,848 patent/US7612113B2/en active Active
- 2003-04-28 AU AU2003229734A patent/AU2003229734B2/en not_active Expired
- 2003-04-28 ES ES03722554T patent/ES2292959T3/es not_active Expired - Lifetime
- 2003-04-28 BR BR0309940-7A patent/BR0309940A/pt not_active IP Right Cessation
- 2003-04-28 DK DK03722554T patent/DK1506167T3/da active
- 2003-04-28 CA CA2487238A patent/CA2487238C/en not_active Expired - Lifetime
- 2003-05-07 TW TW092112380A patent/TWI271396B/zh not_active IP Right Cessation
-
2004
- 2004-11-03 IL IL165004A patent/IL165004A/en not_active IP Right Cessation
- 2004-12-07 HR HR20041167A patent/HRP20041167A2/xx not_active Application Discontinuation
- 2004-12-07 NO NO20045359A patent/NO20045359L/no not_active Application Discontinuation
-
2006
- 2006-03-02 HK HK06102754A patent/HK1082946A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NZ536418A (en) | 2006-04-28 |
EP1506167A1 (en) | 2005-02-16 |
HK1082946A1 (en) | 2006-06-23 |
AU2003229734B2 (en) | 2009-02-19 |
CN1307150C (zh) | 2007-03-28 |
TWI271396B (en) | 2007-01-21 |
PL210288B1 (pl) | 2011-12-30 |
CA2487238A1 (en) | 2003-11-20 |
RU2331635C2 (ru) | 2008-08-20 |
US20060258742A1 (en) | 2006-11-16 |
HRP20041167A2 (en) | 2005-08-31 |
MXPA04010938A (es) | 2005-02-14 |
DK1506167T3 (da) | 2008-01-02 |
ES2292959T3 (es) | 2008-03-16 |
DE60315973T2 (de) | 2008-05-21 |
CA2487238C (en) | 2011-03-22 |
IL165004A0 (en) | 2005-12-18 |
RU2004136281A (ru) | 2005-07-10 |
IL165004A (en) | 2010-12-30 |
PL373257A1 (en) | 2005-08-22 |
AU2003229734A1 (en) | 2003-11-11 |
TW200404052A (en) | 2004-03-16 |
BR0309940A (pt) | 2005-02-09 |
WO2003095420A1 (en) | 2003-11-20 |
JP4335131B2 (ja) | 2009-09-30 |
DE60315973D1 (de) | 2007-10-11 |
EP1506167B1 (en) | 2007-08-29 |
ATE371641T1 (de) | 2007-09-15 |
JP2005524717A (ja) | 2005-08-18 |
CN1665778A (zh) | 2005-09-07 |
US7612113B2 (en) | 2009-11-03 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |