ATE365796T1 - Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta - Google Patents

Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta

Info

Publication number
ATE365796T1
ATE365796T1 AT98901699T AT98901699T ATE365796T1 AT E365796 T1 ATE365796 T1 AT E365796T1 AT 98901699 T AT98901699 T AT 98901699T AT 98901699 T AT98901699 T AT 98901699T AT E365796 T1 ATE365796 T1 AT E365796T1
Authority
AT
Austria
Prior art keywords
necrosis factor
tumor necrosis
tnfr
methods
beta
Prior art date
Application number
AT98901699T
Other languages
German (de)
English (en)
Inventor
Reiner Gentz
Jian Ni
Reinhard Ebner
Guo-Liang Yu
Steven Ruben
Ping Feng
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21883066&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE365796(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Application granted granted Critical
Publication of ATE365796T1 publication Critical patent/ATE365796T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98901699T 1997-01-14 1998-01-13 Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta ATE365796T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3549697P 1997-01-14 1997-01-14

Publications (1)

Publication Number Publication Date
ATE365796T1 true ATE365796T1 (de) 2007-07-15

Family

ID=21883066

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98901699T ATE365796T1 (de) 1997-01-14 1998-01-13 Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta

Country Status (12)

Country Link
US (2) US8003386B1 (enExample)
EP (1) EP1007659B1 (enExample)
JP (1) JP2001507937A (enExample)
KR (1) KR20000070174A (enExample)
CN (1) CN1247567A (enExample)
AT (1) ATE365796T1 (enExample)
AU (1) AU729062C (enExample)
BR (1) BR9806954A (enExample)
CA (1) CA2277925A1 (enExample)
DE (1) DE69837996T2 (enExample)
ES (1) ES2286843T3 (enExample)
WO (1) WO1998030694A2 (enExample)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7597886B2 (en) 1994-11-07 2009-10-06 Human Genome Sciences, Inc. Tumor necrosis factor-gamma
US7429646B1 (en) 1995-06-05 2008-09-30 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor-like 2
US7888466B2 (en) 1996-01-11 2011-02-15 Human Genome Sciences, Inc. Human G-protein chemokine receptor HSATU68
US7357927B2 (en) 1996-03-12 2008-04-15 Human Genome Sciences, Inc. Death domain containing receptors
US6713061B1 (en) 1996-03-12 2004-03-30 Human Genome Sciences, Inc. Death domain containing receptors
WO1997033904A1 (en) 1996-03-12 1997-09-18 Human Genome Sciences, Inc. Death domain containing receptors
US6635743B1 (en) 1996-03-22 2003-10-21 Human Genome Sciences, Inc. Apoptosis inducing molecule II and methods of use
US7964190B2 (en) 1996-03-22 2011-06-21 Human Genome Sciences, Inc. Methods and compositions for decreasing T-cell activity
US7285267B2 (en) 1997-01-14 2007-10-23 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6α & 6β
CA2277925A1 (en) 1997-01-14 1998-07-16 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6.alpha. and 6.beta.
AU9013998A (en) * 1997-07-21 1999-02-10 Zymogenetics Inc. Tumor necrosis factor receptor ztnfr-5
AU8767698A (en) * 1997-08-06 1999-03-01 Procter & Gamble Company, The Novel orphan receptor
AU9376498A (en) * 1997-09-05 1999-03-22 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
ATE393222T1 (de) * 1997-09-18 2008-05-15 Genentech Inc Dcr3 polypeptid, ein tnfr homolog
AU1535699A (en) * 1997-11-24 1999-06-15 Apotech S.A. Novel receptors opg-2
AU1541699A (en) * 1997-12-16 1999-07-05 Incyte Pharmaceuticals, Inc. Human tumor necrosis factor-r2-like proteins
DE19809978A1 (de) * 1998-03-09 1999-09-16 Basf Ag Neuer Rezeptor aus der menschlichen Lunge
CA2324517A1 (en) * 1998-03-30 1999-10-07 Eli Lilly And Company Therapeutic applications of mature flint (mflint) polypeptides or opg3, a member of the tnf receptor superfamily
US6916907B1 (en) * 1998-10-23 2005-07-12 Curagen Corporation Nucleic acids encoding osteoprotegern-like proteins and methods of using same
WO2000034782A1 (en) * 1998-12-09 2000-06-15 Eli Lilly And Company Flint compositions and uses thereof
CA2358508A1 (en) * 1998-12-22 2000-06-29 Eli Lilly And Company Therapeutic applications of flint polypeptides
WO2000046247A1 (en) * 1999-02-05 2000-08-10 Merck & Co., Inc. Methods of use for dna molecules encoding m68, a tnf receptor-related protein
JP2002537769A (ja) 1999-02-26 2002-11-12 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ヒトエンドカインαおよび使用方法
MXPA01008936A (es) * 1999-03-04 2003-07-21 Human Genome Sciences Inc Receptores 6 alfa y 6 beta del factor de necrosis tumoral.
AU2495200A (en) * 1999-03-08 2000-09-28 Genentech Inc. Compositions and methods for the treatment of tumor
ATE371737T1 (de) * 1999-03-30 2007-09-15 Lilly Co Eli Proteaseresistente flint-analoge
US6835814B1 (en) 1999-03-30 2004-12-28 Eli Lilly And Company Protease resistant flint analogs
US6965012B1 (en) * 1999-03-30 2005-11-15 Eli Lilly And Company Flint polypeptide analogs
JP2002539828A (ja) * 1999-03-30 2002-11-26 イーライ・リリー・アンド・カンパニー Ｆｌｉｎｔポリペプチドアナログ
US6627199B1 (en) 1999-07-09 2003-09-30 Amgen Inc Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family
AU6517800A (en) * 1999-08-04 2001-03-05 Amgen, Inc. Ntr3, a member of the tnf-receptor supergene family
JP2003506088A (ja) 1999-08-04 2003-02-18 アムジェン インコーポレーテッド ＴＮＦリガンドスーパー遺伝子ファミリーの新規のメンバーであるＦｈｍ
AU7053000A (en) * 1999-09-10 2001-04-10 Eli Lilly And Company Flint compounds and formulations thereof
EP1214411A2 (en) * 1999-09-10 2002-06-19 Eli Lilly And Company Flint analog compounds and formulations thereof
WO2001018055A1 (en) * 1999-09-10 2001-03-15 Eli Lilly And Company Flint analog compounds and formulations thereof
WO2001096528A2 (en) 2000-06-15 2001-12-20 Human Genome Sciences, Inc. Human tumor necrosis factor delta and epsilon
EP2275449B1 (en) 2000-06-16 2016-09-28 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to BLyS
CN1331125A (zh) * 2000-06-26 2002-01-16 上海博德基因开发有限公司 一种新的多肽——人含细胞色素c结构域的tnfr/ngfr蛋白9.02和编码这种多肽的多核苷酸
WO2002018622A2 (en) * 2000-08-25 2002-03-07 Human Genome Sciences, Inc. TUMOR NECROSIS FACTOR RECEPTORS 6α AND 6$g(b)
DK1572874T3 (da) 2001-05-25 2013-12-16 Human Genome Sciences Inc Antistoffer, der immunospecifikt binder til TRAIL receptorer
AU2002364586A1 (en) 2001-12-21 2003-07-30 Delta Biotechnology Limited Albumin fusion proteins
AU2003265994B2 (en) * 2002-09-11 2010-04-01 Genentech, Inc. Protein purification
EA015860B1 (ru) 2005-10-13 2011-12-30 Хьюман Дженом Сайенсиз, Инк. Способы лечения аутоиммунных заболеваний при использовании антагониста нейтрокина-альфа
WO2007076465A2 (en) * 2005-12-23 2007-07-05 Diadexus, Inc. Cln248 antibody compositions and methods of use
US20110229471A1 (en) 2008-11-26 2011-09-22 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
CN102421913A (zh) * 2009-03-13 2012-04-18 宾夕法尼亚大学董事会 Ox40/trail融合蛋白
AR084141A1 (es) 2010-11-19 2013-04-24 Imai Toshio Anticuerpos neutralizadores anti-ccl20
EP3639841B1 (en) 2013-03-27 2023-09-06 Cedars-Sinai Medical Center Treating fibrosis by inhibiting tl1a
US20160115237A1 (en) 2013-05-24 2016-04-28 The University Of British Columbia Cell senescence markers as diagnostic and therapeutic targets
EP3022295A4 (en) 2013-07-19 2017-03-01 Cedars-Sinai Medical Center Signature of tl1a (tnfsf15) signaling pathway
JP7082945B2 (ja) 2016-03-17 2022-06-09 シーダーズ―シナイ メディカル センター Ｒｎａｓｅｔ２により炎症性腸疾患を診断する方法

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847325A (en) * 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
DE69233441T2 (de) 1991-04-26 2005-10-13 Osaka Bioscience Institute, Suita Menschliches Zelloberflächen-Antigen codierende DNA
NZ275711A (en) 1993-10-14 1998-03-25 Immunex Corp Monoclonal antibodies and binding proteins which bind to human fas antigen (nerve growth factor/tumour necrosis factor receptor type)
US5830469A (en) 1993-10-14 1998-11-03 Immunex Corporation Fas antagonists and uses thereof
US5663070A (en) 1993-11-15 1997-09-02 Lxr Biotechnology Inc. Recombinant production of a soluble splice variant of the Fas (Apo-1) antigen, fas TM
US5741667A (en) 1994-05-27 1998-04-21 Genentech, Inc. Tumor necrosis factor receptor-associated factors
US5632994A (en) 1994-06-14 1997-05-27 La Jolla Cancer Research Foundation Fas associated proteins
JPH11507205A (ja) * 1995-04-27 1999-06-29 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド ヒト腫瘍壊死因子受容体
US5985614A (en) * 1996-08-30 1999-11-16 Human Genome Sciences, Inc. Polynucleotides encoding interleukin-19
CA2277925A1 (en) 1997-01-14 1998-07-16 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6.alpha. and 6.beta.
US5885800A (en) 1997-02-04 1999-03-23 Smithkline Beecham Corporation DNA encoding tumor necrosis related receptor, TR4
WO1998056892A1 (en) 1997-06-11 1998-12-17 Human Genome Sciences, Inc. Human tumor necrosis factor receptor tr9
AU9013998A (en) 1997-07-21 1999-02-10 Zymogenetics Inc. Tumor necrosis factor receptor ztnfr-5
AU8767698A (en) 1997-08-06 1999-03-01 Procter & Gamble Company, The Novel orphan receptor
AU9376498A (en) 1997-09-05 1999-03-22 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
ATE393222T1 (de) 1997-09-18 2008-05-15 Genentech Inc Dcr3 polypeptid, ein tnfr homolog
AU1535699A (en) 1997-11-24 1999-06-15 Apotech S.A. Novel receptors opg-2
AU1541699A (en) 1997-12-16 1999-07-05 Incyte Pharmaceuticals, Inc. Human tumor necrosis factor-r2-like proteins
US6297367B1 (en) 1997-12-30 2001-10-02 Chiron Corporation Polynucleotide encoding TNFL1
AU2093499A (en) 1997-12-30 1999-07-19 Chiron Corporation Members of tnf and tnfr families
DE19809978A1 (de) 1998-03-09 1999-09-16 Basf Ag Neuer Rezeptor aus der menschlichen Lunge
CA2324517A1 (en) 1998-03-30 1999-10-07 Eli Lilly And Company Therapeutic applications of mature flint (mflint) polypeptides or opg3, a member of the tnf receptor superfamily
EP1093516A2 (en) 1998-07-06 2001-04-25 Schering Corporation Mammalian genes; dendritic cell prostaglandin-like transporter (dc-pgt), hdtea84, hsljd37r and rankl, hcc5 chemokine, deubiquitinating 11 and 12 (dub11, dub12), md-1, md2 and cyclin e2, related reagents and methods
ATE458050T1 (de) 1998-12-01 2010-03-15 Genentech Inc Promotion oder inhibition von angiogenese und kardiovaskularisation
WO2000034782A1 (en) 1998-12-09 2000-06-15 Eli Lilly And Company Flint compositions and uses thereof
CA2358508A1 (en) 1998-12-22 2000-06-29 Eli Lilly And Company Therapeutic applications of flint polypeptides
WO2000046247A1 (en) 1999-02-05 2000-08-10 Merck & Co., Inc. Methods of use for dna molecules encoding m68, a tnf receptor-related protein
MXPA01008936A (es) 1999-03-04 2003-07-21 Human Genome Sciences Inc Receptores 6 alfa y 6 beta del factor de necrosis tumoral.
KR20010103046A (ko) 1999-03-08 2001-11-17 제넨테크, 인크. 면역 관련 질환 치료용 조성물 및 치료 방법
AU2495200A (en) 1999-03-08 2000-09-28 Genentech Inc. Compositions and methods for the treatment of tumor
JP2003528030A (ja) 1999-03-11 2003-09-24 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド アポトーシス誘導分子ｉｉ
JP2002539828A (ja) 1999-03-30 2002-11-26 イーライ・リリー・アンド・カンパニー Ｆｌｉｎｔポリペプチドアナログ
ATE371737T1 (de) 1999-03-30 2007-09-15 Lilly Co Eli Proteaseresistente flint-analoge
AU7721500A (en) 1999-09-29 2001-04-30 Human Genome Sciences, Inc. Colon and colon cancer associated polynucleotides and polypeptides
WO2001028582A2 (en) 1999-10-20 2001-04-26 Eli Lilly And Company Therapeutic applications of flint polypeptides
WO2001042463A1 (en) 1999-12-07 2001-06-14 Eli Lilly And Company Improving stability of flint through o-linked glycosylation
WO2001042434A1 (en) 1999-12-09 2001-06-14 Merck & Co., Inc. Dna molecules encoding human nhl, a dna helicase
US20040029123A1 (en) 2000-03-15 2004-02-12 Alexander Olek Diagnosis of diseases associated with the cell cycle
WO2002000677A1 (en) 2000-06-07 2002-01-03 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
AU2001277521A1 (en) 2000-06-30 2002-01-14 Epigenomics Ag Diagnosis of diseases associated with cell signalling
WO2002009668A2 (en) 2000-08-02 2002-02-07 Eli Lilly And Company Pulmonary administration of flint
WO2002060317A2 (en) 2001-01-30 2002-08-08 Corixa Corporation Compositions and methods for the therapy and diagnosis of pancreatic cancer
EP1355945A2 (en) 2001-02-01 2003-10-29 Eli Lilly And Company Flint glycoforms
AU2002246967A1 (en) 2001-02-01 2002-08-12 Eli Lilly And Company Glycoforms a fas ligand inhibitory protein analog
US20040236091A1 (en) 2001-03-28 2004-11-25 Chicz Roman M. Translational profiling
FR2908832B1 (fr) 2006-11-20 2011-08-26 Valeo Systemes Thermiques Carter pour echangeur de chaleur

Also Published As

Publication number Publication date
DE69837996D1 (de) 2007-08-09
AU729062C (en) 2004-03-25
KR20000070174A (ko) 2000-11-25
AU5815798A (en) 1998-08-03
WO1998030694A2 (en) 1998-07-16
EP1007659B1 (en) 2007-06-27
BR9806954A (pt) 2000-03-21
EP1007659A2 (en) 2000-06-14
WO1998030694A3 (en) 1998-11-12
US7186800B1 (en) 2007-03-06
DE69837996T2 (de) 2008-02-28
AU729062B2 (en) 2001-01-25
CN1247567A (zh) 2000-03-15
CA2277925A1 (en) 1998-07-16
ES2286843T3 (es) 2007-12-01
JP2001507937A (ja) 2001-06-19
US8003386B1 (en) 2011-08-23

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