AU729062C - Tumor necrosis factor receptors 6alpha & 6beta - Google Patents
Tumor necrosis factor receptors 6alpha & 6betaInfo
- Publication number
- AU729062C AU729062C AU58157/98A AU5815798A AU729062C AU 729062 C AU729062 C AU 729062C AU 58157/98 A AU58157/98 A AU 58157/98A AU 5815798 A AU5815798 A AU 5815798A AU 729062 C AU729062 C AU 729062C
- Authority
- AU
- Australia
- Prior art keywords
- seq
- tnfr
- polypeptide
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 241000701366 unidentified nuclear polyhedrosis viruses Species 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| PCT/US1998/000153 WO1998030694A2 (en) | 1997-01-14 | 1998-01-13 | TUMOR NECROSIS FACTOR RECEPTORS 6α AND 6$g(b) |
Related Child Applications (1)
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| AU38916/01A Division AU763955C (en) | 1997-01-14 | 2001-04-24 | Tumor necrosis factor receptors 6alpha and 6beta |
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| ES (1) | ES2286843T3 (enExample) |
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| US7597886B2 (en) | 1994-11-07 | 2009-10-06 | Human Genome Sciences, Inc. | Tumor necrosis factor-gamma |
| US7429646B1 (en) | 1995-06-05 | 2008-09-30 | Human Genome Sciences, Inc. | Antibodies to human tumor necrosis factor receptor-like 2 |
| US7888466B2 (en) | 1996-01-11 | 2011-02-15 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor HSATU68 |
| US7357927B2 (en) | 1996-03-12 | 2008-04-15 | Human Genome Sciences, Inc. | Death domain containing receptors |
| US6713061B1 (en) | 1996-03-12 | 2004-03-30 | Human Genome Sciences, Inc. | Death domain containing receptors |
| WO1997033904A1 (en) | 1996-03-12 | 1997-09-18 | Human Genome Sciences, Inc. | Death domain containing receptors |
| US6635743B1 (en) | 1996-03-22 | 2003-10-21 | Human Genome Sciences, Inc. | Apoptosis inducing molecule II and methods of use |
| US7964190B2 (en) | 1996-03-22 | 2011-06-21 | Human Genome Sciences, Inc. | Methods and compositions for decreasing T-cell activity |
| US7285267B2 (en) | 1997-01-14 | 2007-10-23 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6α & 6β |
| CA2277925A1 (en) | 1997-01-14 | 1998-07-16 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6.alpha. and 6.beta. |
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| AU8767698A (en) * | 1997-08-06 | 1999-03-01 | Procter & Gamble Company, The | Novel orphan receptor |
| AU9376498A (en) * | 1997-09-05 | 1999-03-22 | University Of Washington | Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents |
| ATE393222T1 (de) * | 1997-09-18 | 2008-05-15 | Genentech Inc | Dcr3 polypeptid, ein tnfr homolog |
| AU1535699A (en) * | 1997-11-24 | 1999-06-15 | Apotech S.A. | Novel receptors opg-2 |
| AU1541699A (en) * | 1997-12-16 | 1999-07-05 | Incyte Pharmaceuticals, Inc. | Human tumor necrosis factor-r2-like proteins |
| DE19809978A1 (de) * | 1998-03-09 | 1999-09-16 | Basf Ag | Neuer Rezeptor aus der menschlichen Lunge |
| CA2324517A1 (en) * | 1998-03-30 | 1999-10-07 | Eli Lilly And Company | Therapeutic applications of mature flint (mflint) polypeptides or opg3, a member of the tnf receptor superfamily |
| US6916907B1 (en) * | 1998-10-23 | 2005-07-12 | Curagen Corporation | Nucleic acids encoding osteoprotegern-like proteins and methods of using same |
| WO2000034782A1 (en) * | 1998-12-09 | 2000-06-15 | Eli Lilly And Company | Flint compositions and uses thereof |
| CA2358508A1 (en) * | 1998-12-22 | 2000-06-29 | Eli Lilly And Company | Therapeutic applications of flint polypeptides |
| WO2000046247A1 (en) * | 1999-02-05 | 2000-08-10 | Merck & Co., Inc. | Methods of use for dna molecules encoding m68, a tnf receptor-related protein |
| JP2002537769A (ja) | 1999-02-26 | 2002-11-12 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | ヒトエンドカインαおよび使用方法 |
| MXPA01008936A (es) * | 1999-03-04 | 2003-07-21 | Human Genome Sciences Inc | Receptores 6 alfa y 6 beta del factor de necrosis tumoral. |
| AU2495200A (en) * | 1999-03-08 | 2000-09-28 | Genentech Inc. | Compositions and methods for the treatment of tumor |
| ATE371737T1 (de) * | 1999-03-30 | 2007-09-15 | Lilly Co Eli | Proteaseresistente flint-analoge |
| US6835814B1 (en) | 1999-03-30 | 2004-12-28 | Eli Lilly And Company | Protease resistant flint analogs |
| US6965012B1 (en) * | 1999-03-30 | 2005-11-15 | Eli Lilly And Company | Flint polypeptide analogs |
| JP2002539828A (ja) * | 1999-03-30 | 2002-11-26 | イーライ・リリー・アンド・カンパニー | Ｆｌｉｎｔポリペプチドアナログ |
| US6627199B1 (en) | 1999-07-09 | 2003-09-30 | Amgen Inc | Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family |
| AU6517800A (en) * | 1999-08-04 | 2001-03-05 | Amgen, Inc. | Ntr3, a member of the tnf-receptor supergene family |
| JP2003506088A (ja) | 1999-08-04 | 2003-02-18 | アムジェン インコーポレーテッド | ＴＮＦリガンドスーパー遺伝子ファミリーの新規のメンバーであるＦｈｍ |
| AU7053000A (en) * | 1999-09-10 | 2001-04-10 | Eli Lilly And Company | Flint compounds and formulations thereof |
| EP1214411A2 (en) * | 1999-09-10 | 2002-06-19 | Eli Lilly And Company | Flint analog compounds and formulations thereof |
| WO2001018055A1 (en) * | 1999-09-10 | 2001-03-15 | Eli Lilly And Company | Flint analog compounds and formulations thereof |
| WO2001096528A2 (en) | 2000-06-15 | 2001-12-20 | Human Genome Sciences, Inc. | Human tumor necrosis factor delta and epsilon |
| EP2275449B1 (en) | 2000-06-16 | 2016-09-28 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to BLyS |
| CN1331125A (zh) * | 2000-06-26 | 2002-01-16 | 上海博德基因开发有限公司 | 一种新的多肽——人含细胞色素c结构域的tnfr/ngfr蛋白9.02和编码这种多肽的多核苷酸 |
| WO2002018622A2 (en) * | 2000-08-25 | 2002-03-07 | Human Genome Sciences, Inc. | TUMOR NECROSIS FACTOR RECEPTORS 6α AND 6$g(b) |
| DK1572874T3 (da) | 2001-05-25 | 2013-12-16 | Human Genome Sciences Inc | Antistoffer, der immunospecifikt binder til TRAIL receptorer |
| AU2002364586A1 (en) | 2001-12-21 | 2003-07-30 | Delta Biotechnology Limited | Albumin fusion proteins |
| AU2003265994B2 (en) * | 2002-09-11 | 2010-04-01 | Genentech, Inc. | Protein purification |
| EA015860B1 (ru) | 2005-10-13 | 2011-12-30 | Хьюман Дженом Сайенсиз, Инк. | Способы лечения аутоиммунных заболеваний при использовании антагониста нейтрокина-альфа |
| WO2007076465A2 (en) * | 2005-12-23 | 2007-07-05 | Diadexus, Inc. | Cln248 antibody compositions and methods of use |
| US20110229471A1 (en) | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
| CN102421913A (zh) * | 2009-03-13 | 2012-04-18 | 宾夕法尼亚大学董事会 | Ox40/trail融合蛋白 |
| AR084141A1 (es) | 2010-11-19 | 2013-04-24 | Imai Toshio | Anticuerpos neutralizadores anti-ccl20 |
| EP3639841B1 (en) | 2013-03-27 | 2023-09-06 | Cedars-Sinai Medical Center | Treating fibrosis by inhibiting tl1a |
| US20160115237A1 (en) | 2013-05-24 | 2016-04-28 | The University Of British Columbia | Cell senescence markers as diagnostic and therapeutic targets |
| EP3022295A4 (en) | 2013-07-19 | 2017-03-01 | Cedars-Sinai Medical Center | Signature of tl1a (tnfsf15) signaling pathway |
| JP7082945B2 (ja) | 2016-03-17 | 2022-06-09 | シーダーズ―シナイ メディカル センター | Ｒｎａｓｅｔ２により炎症性腸疾患を診断する方法 |
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| US4847325A (en) * | 1988-01-20 | 1989-07-11 | Cetus Corporation | Conjugation of polymer to colony stimulating factor-1 |
| US5194596A (en) * | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
| US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
| DE69233441T2 (de) | 1991-04-26 | 2005-10-13 | Osaka Bioscience Institute, Suita | Menschliches Zelloberflächen-Antigen codierende DNA |
| NZ275711A (en) | 1993-10-14 | 1998-03-25 | Immunex Corp | Monoclonal antibodies and binding proteins which bind to human fas antigen (nerve growth factor/tumour necrosis factor receptor type) |
| US5830469A (en) | 1993-10-14 | 1998-11-03 | Immunex Corporation | Fas antagonists and uses thereof |
| US5663070A (en) | 1993-11-15 | 1997-09-02 | Lxr Biotechnology Inc. | Recombinant production of a soluble splice variant of the Fas (Apo-1) antigen, fas TM |
| US5741667A (en) | 1994-05-27 | 1998-04-21 | Genentech, Inc. | Tumor necrosis factor receptor-associated factors |
| US5632994A (en) | 1994-06-14 | 1997-05-27 | La Jolla Cancer Research Foundation | Fas associated proteins |
| JPH11507205A (ja) * | 1995-04-27 | 1999-06-29 | ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド | ヒト腫瘍壊死因子受容体 |
| US5985614A (en) * | 1996-08-30 | 1999-11-16 | Human Genome Sciences, Inc. | Polynucleotides encoding interleukin-19 |
| CA2277925A1 (en) | 1997-01-14 | 1998-07-16 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6.alpha. and 6.beta. |
| US5885800A (en) | 1997-02-04 | 1999-03-23 | Smithkline Beecham Corporation | DNA encoding tumor necrosis related receptor, TR4 |
| WO1998056892A1 (en) | 1997-06-11 | 1998-12-17 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor tr9 |
| AU9013998A (en) | 1997-07-21 | 1999-02-10 | Zymogenetics Inc. | Tumor necrosis factor receptor ztnfr-5 |
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| AU9376498A (en) | 1997-09-05 | 1999-03-22 | University Of Washington | Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents |
| ATE393222T1 (de) | 1997-09-18 | 2008-05-15 | Genentech Inc | Dcr3 polypeptid, ein tnfr homolog |
| AU1535699A (en) | 1997-11-24 | 1999-06-15 | Apotech S.A. | Novel receptors opg-2 |
| AU1541699A (en) | 1997-12-16 | 1999-07-05 | Incyte Pharmaceuticals, Inc. | Human tumor necrosis factor-r2-like proteins |
| US6297367B1 (en) | 1997-12-30 | 2001-10-02 | Chiron Corporation | Polynucleotide encoding TNFL1 |
| AU2093499A (en) | 1997-12-30 | 1999-07-19 | Chiron Corporation | Members of tnf and tnfr families |
| DE19809978A1 (de) | 1998-03-09 | 1999-09-16 | Basf Ag | Neuer Rezeptor aus der menschlichen Lunge |
| CA2324517A1 (en) | 1998-03-30 | 1999-10-07 | Eli Lilly And Company | Therapeutic applications of mature flint (mflint) polypeptides or opg3, a member of the tnf receptor superfamily |
| EP1093516A2 (en) | 1998-07-06 | 2001-04-25 | Schering Corporation | Mammalian genes; dendritic cell prostaglandin-like transporter (dc-pgt), hdtea84, hsljd37r and rankl, hcc5 chemokine, deubiquitinating 11 and 12 (dub11, dub12), md-1, md2 and cyclin e2, related reagents and methods |
| ATE458050T1 (de) | 1998-12-01 | 2010-03-15 | Genentech Inc | Promotion oder inhibition von angiogenese und kardiovaskularisation |
| WO2000034782A1 (en) | 1998-12-09 | 2000-06-15 | Eli Lilly And Company | Flint compositions and uses thereof |
| CA2358508A1 (en) | 1998-12-22 | 2000-06-29 | Eli Lilly And Company | Therapeutic applications of flint polypeptides |
| WO2000046247A1 (en) | 1999-02-05 | 2000-08-10 | Merck & Co., Inc. | Methods of use for dna molecules encoding m68, a tnf receptor-related protein |
| MXPA01008936A (es) | 1999-03-04 | 2003-07-21 | Human Genome Sciences Inc | Receptores 6 alfa y 6 beta del factor de necrosis tumoral. |
| KR20010103046A (ko) | 1999-03-08 | 2001-11-17 | 제넨테크, 인크. | 면역 관련 질환 치료용 조성물 및 치료 방법 |
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| JP2003528030A (ja) | 1999-03-11 | 2003-09-24 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | アポトーシス誘導分子ｉｉ |
| JP2002539828A (ja) | 1999-03-30 | 2002-11-26 | イーライ・リリー・アンド・カンパニー | Ｆｌｉｎｔポリペプチドアナログ |
| ATE371737T1 (de) | 1999-03-30 | 2007-09-15 | Lilly Co Eli | Proteaseresistente flint-analoge |
| AU7721500A (en) | 1999-09-29 | 2001-04-30 | Human Genome Sciences, Inc. | Colon and colon cancer associated polynucleotides and polypeptides |
| WO2001028582A2 (en) | 1999-10-20 | 2001-04-26 | Eli Lilly And Company | Therapeutic applications of flint polypeptides |
| WO2001042463A1 (en) | 1999-12-07 | 2001-06-14 | Eli Lilly And Company | Improving stability of flint through o-linked glycosylation |
| WO2001042434A1 (en) | 1999-12-09 | 2001-06-14 | Merck & Co., Inc. | Dna molecules encoding human nhl, a dna helicase |
| US20040029123A1 (en) | 2000-03-15 | 2004-02-12 | Alexander Olek | Diagnosis of diseases associated with the cell cycle |
| WO2002000677A1 (en) | 2000-06-07 | 2002-01-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| AU2001277521A1 (en) | 2000-06-30 | 2002-01-14 | Epigenomics Ag | Diagnosis of diseases associated with cell signalling |
| WO2002009668A2 (en) | 2000-08-02 | 2002-02-07 | Eli Lilly And Company | Pulmonary administration of flint |
| WO2002060317A2 (en) | 2001-01-30 | 2002-08-08 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of pancreatic cancer |
| EP1355945A2 (en) | 2001-02-01 | 2003-10-29 | Eli Lilly And Company | Flint glycoforms |
| AU2002246967A1 (en) | 2001-02-01 | 2002-08-12 | Eli Lilly And Company | Glycoforms a fas ligand inhibitory protein analog |
| US20040236091A1 (en) | 2001-03-28 | 2004-11-25 | Chicz Roman M. | Translational profiling |
| FR2908832B1 (fr) | 2006-11-20 | 2011-08-26 | Valeo Systemes Thermiques | Carter pour echangeur de chaleur |
-
1998
- 1998-01-13 CA CA002277925A patent/CA2277925A1/en not_active Abandoned
- 1998-01-13 WO PCT/US1998/000153 patent/WO1998030694A2/en not_active Ceased
- 1998-01-13 AT AT98901699T patent/ATE365796T1/de not_active IP Right Cessation
- 1998-01-13 BR BR9806954A patent/BR9806954A/pt not_active IP Right Cessation
- 1998-01-13 KR KR1019997006400A patent/KR20000070174A/ko not_active Ceased
- 1998-01-13 ES ES98901699T patent/ES2286843T3/es not_active Expired - Lifetime
- 1998-01-13 AU AU58157/98A patent/AU729062C/en not_active Ceased
- 1998-01-13 DE DE69837996T patent/DE69837996T2/de not_active Expired - Fee Related
- 1998-01-13 JP JP53103798A patent/JP2001507937A/ja not_active Withdrawn
- 1998-01-13 EP EP98901699A patent/EP1007659B1/en not_active Expired - Lifetime
- 1998-01-13 US US09/006,352 patent/US8003386B1/en active Active
- 1998-01-13 CN CN98801836A patent/CN1247567A/zh active Pending
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2000
- 2000-03-03 US US09/518,931 patent/US7186800B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69837996D1 (de) | 2007-08-09 |
| KR20000070174A (ko) | 2000-11-25 |
| AU5815798A (en) | 1998-08-03 |
| WO1998030694A2 (en) | 1998-07-16 |
| EP1007659B1 (en) | 2007-06-27 |
| BR9806954A (pt) | 2000-03-21 |
| ATE365796T1 (de) | 2007-07-15 |
| EP1007659A2 (en) | 2000-06-14 |
| WO1998030694A3 (en) | 1998-11-12 |
| US7186800B1 (en) | 2007-03-06 |
| DE69837996T2 (de) | 2008-02-28 |
| AU729062B2 (en) | 2001-01-25 |
| CN1247567A (zh) | 2000-03-15 |
| CA2277925A1 (en) | 1998-07-16 |
| ES2286843T3 (es) | 2007-12-01 |
| JP2001507937A (ja) | 2001-06-19 |
| US8003386B1 (en) | 2011-08-23 |
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