ATE365796T1 - Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta - Google Patents

Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta

Info

Publication number
ATE365796T1
ATE365796T1 AT98901699T AT98901699T ATE365796T1 AT E365796 T1 ATE365796 T1 AT E365796T1 AT 98901699 T AT98901699 T AT 98901699T AT 98901699 T AT98901699 T AT 98901699T AT E365796 T1 ATE365796 T1 AT E365796T1
Authority
AT
Austria
Prior art keywords
necrosis factor
tumor necrosis
tnfr
methods
beta
Prior art date
Application number
AT98901699T
Other languages
English (en)
Inventor
Reiner Gentz
Jian Ni
Reinhard Ebner
Guo-Liang Yu
Steven Ruben
Ping Feng
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21883066&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE365796(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Application granted granted Critical
Publication of ATE365796T1 publication Critical patent/ATE365796T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT98901699T 1997-01-14 1998-01-13 Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta ATE365796T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3549697P 1997-01-14 1997-01-14

Publications (1)

Publication Number Publication Date
ATE365796T1 true ATE365796T1 (de) 2007-07-15

Family

ID=21883066

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98901699T ATE365796T1 (de) 1997-01-14 1998-01-13 Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta

Country Status (12)

Country Link
US (2) US8003386B1 (de)
EP (1) EP1007659B1 (de)
JP (1) JP2001507937A (de)
KR (1) KR20000070174A (de)
CN (1) CN1247567A (de)
AT (1) ATE365796T1 (de)
AU (1) AU729062C (de)
BR (1) BR9806954A (de)
CA (1) CA2277925A1 (de)
DE (1) DE69837996T2 (de)
ES (1) ES2286843T3 (de)
WO (1) WO1998030694A2 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7888466B2 (en) 1996-01-11 2011-02-15 Human Genome Sciences, Inc. Human G-protein chemokine receptor HSATU68
US7357927B2 (en) 1996-03-12 2008-04-15 Human Genome Sciences, Inc. Death domain containing receptors
US6713061B1 (en) 1996-03-12 2004-03-30 Human Genome Sciences, Inc. Death domain containing receptors
WO1997033904A1 (en) 1996-03-12 1997-09-18 Human Genome Sciences, Inc. Death domain containing receptors
US6635743B1 (en) 1996-03-22 2003-10-21 Human Genome Sciences, Inc. Apoptosis inducing molecule II and methods of use
US7964190B2 (en) 1996-03-22 2011-06-21 Human Genome Sciences, Inc. Methods and compositions for decreasing T-cell activity
EP1007659B1 (de) 1997-01-14 2007-06-27 Human Genome Sciences, Inc. Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta
US7285267B2 (en) 1997-01-14 2007-10-23 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6α & 6β
AU9013998A (en) * 1997-07-21 1999-02-10 Zymogenetics Inc. Tumor necrosis factor receptor ztnfr-5
EP1019502A2 (de) * 1997-08-06 2000-07-19 Regeneron Pharmaceuticals, Inc. Humane waisenrezeptor ntr-1
WO1999011791A2 (en) * 1997-09-05 1999-03-11 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
IL134578A0 (en) * 1997-09-18 2001-04-30 Genentech Inc DcR3 POLYPEPTIDE, A TNFR HOMOLOG
WO1999026977A1 (en) * 1997-11-24 1999-06-03 Biogen, Inc. Novel receptors opg-2
EP1037908A2 (de) * 1997-12-16 2000-09-27 Incyte Pharmaceuticals, Inc. Menschlicher tumor nekrose factor r2-ähnlicher rezeptor
DE19809978A1 (de) * 1998-03-09 1999-09-16 Basf Ag Neuer Rezeptor aus der menschlichen Lunge
PL343847A1 (en) * 1998-03-30 2001-09-10 Lilly Co Eli Therapeutic applications of mature flint (mflint) polypeptides or opg3, a member of the tnf receptor superfamily
US6916907B1 (en) * 1998-10-23 2005-07-12 Curagen Corporation Nucleic acids encoding osteoprotegern-like proteins and methods of using same
WO2000034782A1 (en) * 1998-12-09 2000-06-15 Eli Lilly And Company Flint compositions and uses thereof
WO2000037094A2 (en) * 1998-12-22 2000-06-29 Eli Lilly And Company Therapeutic applications of flint polypeptides
WO2000046247A1 (en) * 1999-02-05 2000-08-10 Merck & Co., Inc. Methods of use for dna molecules encoding m68, a tnf receptor-related protein
EP2357192A1 (de) 1999-02-26 2011-08-17 Human Genome Sciences, Inc. Menschliches alpha-Endokin und Verfahren zu seiner Verwendung
CN1345329A (zh) * 1999-03-04 2002-04-17 人体基因组科学有限公司 肿瘤坏死因子受体6α和6β
AU2495200A (en) * 1999-03-08 2000-09-28 Genentech Inc. Compositions and methods for the treatment of tumor
EP1165781B1 (de) * 1999-03-30 2007-08-29 Eli Lilly And Company Proteaseresistente flint-analoge
US6965012B1 (en) * 1999-03-30 2005-11-15 Eli Lilly And Company Flint polypeptide analogs
US6835814B1 (en) 1999-03-30 2004-12-28 Eli Lilly And Company Protease resistant flint analogs
AU3739400A (en) * 1999-03-30 2000-10-16 Eli Lilly And Company Flint polypeptide analogs
US6627199B1 (en) 1999-07-09 2003-09-30 Amgen Inc Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family
MXPA02001264A (es) 1999-08-04 2002-07-22 Amgen Inc Fhm, nuevo miembro de la familia de supergenes de ligando de factor de necrosis tumoral.
AU6517800A (en) 1999-08-04 2001-03-05 Amgen, Inc. Ntr3, a member of the tnf-receptor supergene family
AU7053100A (en) * 1999-09-10 2001-04-10 Eli Lilly And Company Flint analog compounds and formulations thereof
WO2001018041A2 (en) * 1999-09-10 2001-03-15 Eli Lilly And Company Flint proteins and formulations thereof
AU6891800A (en) * 1999-09-10 2001-04-10 Eli Lilly And Company Flint analog compounds and formulations thereof
EP1294949A4 (de) 2000-06-15 2004-08-25 Human Genome Sciences Inc Menschlicher tumornekrosefaktor delta und epsilon
AU6842701A (en) 2000-06-16 2002-01-14 Human Genome Sciences Inc Antibodies that immunospecifically bind to blys
CN1331125A (zh) * 2000-06-26 2002-01-16 上海博德基因开发有限公司 一种新的多肽——人含细胞色素c结构域的tnfr/ngfr蛋白9.02和编码这种多肽的多核苷酸
CA2420593A1 (en) * 2000-08-25 2002-03-07 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6.alpha. and 6.beta.
JP4309758B2 (ja) 2001-05-25 2009-08-05 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド Ｔｒａｉｌレセプターに免疫特異的に結合する抗体
PT1463751E (pt) 2001-12-21 2013-08-26 Human Genome Sciences Inc Proteínas de fusão de albumina
HUE033623T2 (en) 2002-09-11 2017-12-28 Genentech Inc protein purification
AU2006344395B2 (en) 2005-10-13 2013-05-02 Human Genome Sciences, Inc. Methods and compositions for use in treatment of patients with autoantibody positive diseases
WO2007076465A2 (en) * 2005-12-23 2007-07-05 Diadexus, Inc. Cln248 antibody compositions and methods of use
US20110229471A1 (en) 2008-11-26 2011-09-22 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
AU2010224094A1 (en) * 2009-03-13 2011-09-22 The Trustees Of The University Of Pennsylvania OX40/TRAIL fusion proteins
EP2640744A4 (de) 2010-11-19 2014-05-28 Eisai R&D Man Co Ltd Neutralisierung von antikörpern gegen ccl20
KR20210157418A (ko) 2013-03-27 2021-12-28 세다르스-신나이 메디칼 센터 Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전
WO2014186877A1 (en) 2013-05-24 2014-11-27 Uger Marni Diane FasR ANTIBODIES FOR DIAGNOSTIC AND THERAPEUTIC USE
EP4105236A1 (de) 2013-07-19 2022-12-21 Cedars-Sinai Medical Center Anti-tl1a (tnfsf15) antikörper zur behandlung von entzündlichen darmerkrankungen
EP3430172A4 (de) 2016-03-17 2019-08-21 Cedars-Sinai Medical Center Verfahren zur diagnose einer entzündlichen darmerkrankung durch rnaset2

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847325A (en) * 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
CA2067031C (en) 1991-04-26 2003-02-18 Shigekazu Nagata Dna coding for human cell surface antigen
US5620889A (en) 1993-10-14 1997-04-15 Immunex Corporation Human anti-Fas IgG1 monoclonal antibodies
US5830469A (en) 1993-10-14 1998-11-03 Immunex Corporation Fas antagonists and uses thereof
US5663070A (en) 1993-11-15 1997-09-02 Lxr Biotechnology Inc. Recombinant production of a soluble splice variant of the Fas (Apo-1) antigen, fas TM
US5741667A (en) * 1994-05-27 1998-04-21 Genentech, Inc. Tumor necrosis factor receptor-associated factors
US5632994A (en) 1994-06-14 1997-05-27 La Jolla Cancer Research Foundation Fas associated proteins
AU2363695A (en) * 1995-04-27 1996-11-18 Human Genome Sciences, Inc. Human tumor necrosis factor receptors
US5985614A (en) * 1996-08-30 1999-11-16 Human Genome Sciences, Inc. Polynucleotides encoding interleukin-19
EP1007659B1 (de) 1997-01-14 2007-06-27 Human Genome Sciences, Inc. Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta
US5885800A (en) 1997-02-04 1999-03-23 Smithkline Beecham Corporation DNA encoding tumor necrosis related receptor, TR4
AU7830398A (en) 1997-06-11 1998-12-30 Human Genome Sciences, Inc. Human tumor necrosis factor receptor tr9
AU9013998A (en) 1997-07-21 1999-02-10 Zymogenetics Inc. Tumor necrosis factor receptor ztnfr-5
EP1019502A2 (de) 1997-08-06 2000-07-19 Regeneron Pharmaceuticals, Inc. Humane waisenrezeptor ntr-1
WO1999011791A2 (en) 1997-09-05 1999-03-11 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
IL134578A0 (en) 1997-09-18 2001-04-30 Genentech Inc DcR3 POLYPEPTIDE, A TNFR HOMOLOG
WO1999026977A1 (en) 1997-11-24 1999-06-03 Biogen, Inc. Novel receptors opg-2
EP1037908A2 (de) 1997-12-16 2000-09-27 Incyte Pharmaceuticals, Inc. Menschlicher tumor nekrose factor r2-ähnlicher rezeptor
US6297367B1 (en) 1997-12-30 2001-10-02 Chiron Corporation Polynucleotide encoding TNFL1
AU2093499A (en) 1997-12-30 1999-07-19 Chiron Corporation Members of tnf and tnfr families
DE19809978A1 (de) 1998-03-09 1999-09-16 Basf Ag Neuer Rezeptor aus der menschlichen Lunge
PL343847A1 (en) 1998-03-30 2001-09-10 Lilly Co Eli Therapeutic applications of mature flint (mflint) polypeptides or opg3, a member of the tnf receptor superfamily
CA2332573A1 (en) 1998-07-06 2000-01-13 Elizabeth Esther Mary Bates Mammalian genes; dendritic cell prostaglandin-like transponder (dc-pgt), hdtea84, hsljd37r and rankl, hcc5 chemokine, deubiquitinating 11 and 12 (dub11, dub12), md-1, md2 and cyclin e2, related reagents and methods
ATE458050T1 (de) 1998-12-01 2010-03-15 Genentech Inc Promotion oder inhibition von angiogenese und kardiovaskularisation
WO2000034782A1 (en) 1998-12-09 2000-06-15 Eli Lilly And Company Flint compositions and uses thereof
WO2000037094A2 (en) 1998-12-22 2000-06-29 Eli Lilly And Company Therapeutic applications of flint polypeptides
WO2000046247A1 (en) 1999-02-05 2000-08-10 Merck & Co., Inc. Methods of use for dna molecules encoding m68, a tnf receptor-related protein
CN1345329A (zh) 1999-03-04 2002-04-17 人体基因组科学有限公司 肿瘤坏死因子受体6α和6β
AU2495200A (en) 1999-03-08 2000-09-28 Genentech Inc. Compositions and methods for the treatment of tumor
EP1220905A2 (de) 1999-03-08 2002-07-10 Genentech Inc. Zusammensetzung und verfahren zur behandlung von immunverwandten krankheiten
AU3623700A (en) 1999-03-11 2000-09-28 Reinhard Ebner Apoptosis inducing molecule ii and methods of use
AU3739400A (en) 1999-03-30 2000-10-16 Eli Lilly And Company Flint polypeptide analogs
EP1165781B1 (de) 1999-03-30 2007-08-29 Eli Lilly And Company Proteaseresistente flint-analoge
AU7721500A (en) 1999-09-29 2001-04-30 Human Genome Sciences, Inc. Colon and colon cancer associated polynucleotides and polypeptides
AU1189101A (en) 1999-10-20 2001-04-30 Eli Lilly And Company Therapeutic applications of flint polypeptides
AU1915201A (en) 1999-12-07 2001-06-18 Eli Lilly And Company Improving stability of flint through o-linked glycosylation
CA2395378A1 (en) 1999-12-09 2001-06-14 Merck & Co. Inc. Dna molecules encoding human nhl, a dna helicase
AU2001248352A1 (en) 2000-03-15 2001-09-24 Epigenomics Ag Diagnosis of diseases associated with the cell cycle
WO2002000677A1 (en) 2000-06-07 2002-01-03 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2002000926A2 (en) 2000-06-30 2002-01-03 Epigenomics Ag Diagnosis of diseases associated with signal transduction
WO2002009668A2 (en) 2000-08-02 2002-02-07 Eli Lilly And Company Pulmonary administration of flint
AU2002251841A1 (en) 2001-01-30 2002-08-12 Corixa Corporation Compositions and methods for the therapy and diagnosis of pancreatic cancer
AU2002246967A1 (en) 2001-02-01 2002-08-12 Eli Lilly And Company Glycoforms a fas ligand inhibitory protein analog
EP1355945A2 (de) 2001-02-01 2003-10-29 Eli Lilly And Company Glycoformen von flint
WO2002078524A2 (en) 2001-03-28 2002-10-10 Zycos Inc. Translational profiling
FR2908832B1 (fr) 2006-11-20 2011-08-26 Valeo Systemes Thermiques Carter pour echangeur de chaleur

Also Published As

Publication number Publication date
AU729062B2 (en) 2001-01-25
ES2286843T3 (es) 2007-12-01
WO1998030694A3 (en) 1998-11-12
US7186800B1 (en) 2007-03-06
EP1007659A2 (de) 2000-06-14
AU5815798A (en) 1998-08-03
CA2277925A1 (en) 1998-07-16
AU729062C (en) 2004-03-25
US8003386B1 (en) 2011-08-23
EP1007659B1 (de) 2007-06-27
KR20000070174A (ko) 2000-11-25
BR9806954A (pt) 2000-03-21
DE69837996D1 (de) 2007-08-09
CN1247567A (zh) 2000-03-15
DE69837996T2 (de) 2008-02-28
WO1998030694A2 (en) 1998-07-16
JP2001507937A (ja) 2001-06-19

Similar Documents

Publication Publication Date Title
ATE365796T1 (de) Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta
DE69841140D1 (de) Interleukin-17 rezeptor-ähnliches protein
ATE302272T1 (de) Neutrokin alpha
WO1998031806A3 (en) Fc receptors and polypeptides
NZ510367A (en) Interleukin 17-like receptor protein nucleic acid sequence encoding the interleukin receptor protein and method of expressing protein in recombinant vector
DE69836956D1 (de) Rezeptor 5, der eine für den zelltod verantwortliche domäne enthält
WO1998031818A3 (en) Tace-like and matrilysin-like polypeptides
DE69834027D1 (de) Tumor-nekrose-faktor rezeptor 5
ATE131871T1 (de) Rezeptoren für tumornekrosisfaktor-alpha und - beta
AU6250098A (en) Death domain containing receptor 4 (dr4: death receptor 4), member of the tnf-receptor superfamily and binding to trail (ap02-l)
WO2000043493A8 (en) Metalloproteinase adam 22
WO2000056405A3 (en) Human tumor necrosis factor receptor-like 2
ATE472599T1 (de) Chemokin alpha-5
WO1998053069A3 (en) Gdnf receptors
ATE300554T1 (de) Bindegewebe-wachstumsfaktor 3.
EP1187842A4 (de) Der tr10 rezeptor des menschlichen tumor-nekrose-faktors
WO2001032128A3 (en) Human chemokine beta-13
WO2002018622A3 (en) TUMOR NECROSIS FACTOR RECEPTORS 6α AND 6$g(b)
WO2000039136A3 (en) Human brainiac-5
EP1712631A3 (de) Fc Rezeptoren
WO2001005834A9 (en) Human tumor necrosis factor receptors tr13 and tr14
WO2002057421A3 (en) Human tumor necrosis factor receptors tr13 and tr14

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee