ATE353879T1 - Verfahren zur herstellung von chinolinderivaten - Google Patents
Verfahren zur herstellung von chinolinderivatenInfo
- Publication number
- ATE353879T1 ATE353879T1 AT98947099T AT98947099T ATE353879T1 AT E353879 T1 ATE353879 T1 AT E353879T1 AT 98947099 T AT98947099 T AT 98947099T AT 98947099 T AT98947099 T AT 98947099T AT E353879 T1 ATE353879 T1 AT E353879T1
- Authority
- AT
- Austria
- Prior art keywords
- quinoline derivatives
- producing quinoline
- producing
- derivatives
- quinoline
- Prior art date
Links
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical class N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title 1
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5930397P | 1997-09-17 | 1997-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE353879T1 true ATE353879T1 (de) | 2007-03-15 |
Family
ID=22022126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98947099T ATE353879T1 (de) | 1997-09-17 | 1998-09-17 | Verfahren zur herstellung von chinolinderivaten |
Country Status (32)
| Country | Link |
|---|---|
| US (6) | US6335448B1 (de) |
| EP (1) | EP1017676B1 (de) |
| JP (1) | JP2001516744A (de) |
| KR (1) | KR20010024031A (de) |
| CN (1) | CN1125815C (de) |
| AP (1) | AP1201A (de) |
| AR (1) | AR015445A1 (de) |
| AT (1) | ATE353879T1 (de) |
| AU (1) | AU744538B2 (de) |
| BG (1) | BG104243A (de) |
| BR (1) | BR9812085A (de) |
| CA (1) | CA2303026A1 (de) |
| DE (1) | DE69837100T2 (de) |
| DZ (1) | DZ2607A1 (de) |
| EA (1) | EA002633B1 (de) |
| ES (1) | ES2283072T3 (de) |
| HU (1) | HUP0004855A3 (de) |
| ID (1) | ID24140A (de) |
| IL (1) | IL134991A0 (de) |
| MA (1) | MA24644A1 (de) |
| MY (1) | MY120237A (de) |
| NO (1) | NO314303B1 (de) |
| NZ (1) | NZ503307A (de) |
| OA (1) | OA11340A (de) |
| PE (1) | PE129299A1 (de) |
| PL (1) | PL339340A1 (de) |
| SK (1) | SK3672000A3 (de) |
| TR (1) | TR200000720T2 (de) |
| TW (1) | TW509678B (de) |
| UY (2) | UY25174A1 (de) |
| WO (1) | WO1999014196A1 (de) |
| ZA (1) | ZA988455B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP1201A (en) * | 1997-09-17 | 2003-09-01 | Smithkline Beecham Corp | Method for the synthesis of quinoline derivatives. |
| EP1165542B1 (de) | 1999-03-29 | 2003-08-20 | Neurogen Corporation | 4-substituierte chinolinderivate als nk-3 und/oder gaba(a) rezeptor liganden |
| CA2555133A1 (en) | 2004-02-04 | 2005-09-01 | Pfizer Products Inc. | Substituted quinoline compounds |
| WO2006130080A2 (en) * | 2005-06-03 | 2006-12-07 | Astrazeneca Ab | Quinoline derivatives as nk3 anatgonists |
| US20080194623A1 (en) * | 2005-08-02 | 2008-08-14 | Labaw Clifford S | Method for the Synthesis of Quinoline Derivatives |
| JP2009504642A (ja) * | 2005-08-11 | 2009-02-05 | アストラゼネカ・アクチエボラーグ | Ｎｋ−３受容体の調節剤としてのオキソピリジルキノリンアミド |
| AR057130A1 (es) * | 2005-09-21 | 2007-11-14 | Astrazeneca Ab | Quinolinas de alquilsulfoxido y una composicion farmaceutica |
| JP2009508944A (ja) * | 2005-09-21 | 2009-03-05 | アストラゼネカ・アクチエボラーグ | Ｎｋ−３受容体リガンドとしてのｎ−オキソ複素環及びｎ−オキソ−アルキルキノリン−４−カルボキシアミド類 |
| JP2009524656A (ja) * | 2006-01-27 | 2009-07-02 | アストラゼネカ・アクチエボラーグ | アミド置換キノリン |
| CN102924375B (zh) * | 2012-06-21 | 2015-02-18 | 江苏恩华药业股份有限公司 | Talnetant中间体及其制备方法和应用 |
| CN102702099A (zh) * | 2012-06-21 | 2012-10-03 | 江苏恩华药业股份有限公司 | (s)-3-羟基-2-苯基-n-(1-苯基丙基)喹啉-4-甲酰胺的制备方法 |
| CN103214416A (zh) * | 2013-04-26 | 2013-07-24 | 扬州大学 | 一种合成多取代喹啉类化合物的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2776290A (en) * | 1957-01-01 | Hydroxy cevchoninates and carboxylic | ||
| ES2227769T3 (es) * | 1994-05-27 | 2005-04-01 | Glaxosmithkline S.P.A. | Derivados de quinolina como antagonistas del receptor nk3 de taquiquinina. |
| US5627193A (en) * | 1995-02-09 | 1997-05-06 | Mitsui Toatsu Chemicals, Inc. | Quinoline-4-carbonylguanidine derivatives, process for producing the same and pharmaceutical preparations containing the compounds |
| AP1201A (en) * | 1997-09-17 | 2003-09-01 | Smithkline Beecham Corp | Method for the synthesis of quinoline derivatives. |
-
1998
- 1998-05-08 AP APAP/P/2000/001767A patent/AP1201A/en active
- 1998-09-08 MA MA25246A patent/MA24644A1/fr unknown
- 1998-09-08 UY UY25174A patent/UY25174A1/es not_active Application Discontinuation
- 1998-09-11 PE PE1998000868A patent/PE129299A1/es not_active Application Discontinuation
- 1998-09-14 DZ DZ980217A patent/DZ2607A1/xx active
- 1998-09-15 MY MYPI98004207A patent/MY120237A/en unknown
- 1998-09-16 AR ARP980104603A patent/AR015445A1/es not_active Application Discontinuation
- 1998-09-16 ZA ZA988455A patent/ZA988455B/xx unknown
- 1998-09-17 AU AU93958/98A patent/AU744538B2/en not_active Ceased
- 1998-09-17 PL PL98339340A patent/PL339340A1/xx unknown
- 1998-09-17 AT AT98947099T patent/ATE353879T1/de not_active IP Right Cessation
- 1998-09-17 DE DE69837100T patent/DE69837100T2/de not_active Expired - Lifetime
- 1998-09-17 CA CA002303026A patent/CA2303026A1/en not_active Abandoned
- 1998-09-17 EA EA200000322A patent/EA002633B1/ru not_active IP Right Cessation
- 1998-09-17 HU HU0004855A patent/HUP0004855A3/hu unknown
- 1998-09-17 CN CN98810978A patent/CN1125815C/zh not_active Expired - Fee Related
- 1998-09-17 BR BR9812085-9A patent/BR9812085A/pt not_active IP Right Cessation
- 1998-09-17 JP JP2000511747A patent/JP2001516744A/ja active Pending
- 1998-09-17 WO PCT/US1998/019434 patent/WO1999014196A1/en not_active Ceased
- 1998-09-17 EP EP98947099A patent/EP1017676B1/de not_active Expired - Lifetime
- 1998-09-17 NZ NZ503307A patent/NZ503307A/en unknown
- 1998-09-17 KR KR1020007002766A patent/KR20010024031A/ko not_active Ceased
- 1998-09-17 ES ES98947099T patent/ES2283072T3/es not_active Expired - Lifetime
- 1998-09-17 ID IDW20000498A patent/ID24140A/id unknown
- 1998-09-17 SK SK367-2000A patent/SK3672000A3/sk unknown
- 1998-09-17 US US09/508,358 patent/US6335448B1/en not_active Expired - Fee Related
- 1998-09-17 IL IL13499198A patent/IL134991A0/xx unknown
- 1998-09-17 TR TR2000/00720T patent/TR200000720T2/xx unknown
- 1998-09-29 TW TW087114858A patent/TW509678B/zh not_active IP Right Cessation
-
1999
- 1999-02-26 UY UY25407A patent/UY25407A1/es unknown
-
2000
- 2000-03-15 BG BG104243A patent/BG104243A/xx unknown
- 2000-03-16 OA OA1200000078A patent/OA11340A/en unknown
- 2000-03-16 NO NO20001387A patent/NO314303B1/no not_active IP Right Cessation
-
2001
- 2001-10-17 US US09/981,185 patent/US20020038029A1/en not_active Abandoned
-
2002
- 2002-06-17 US US10/174,458 patent/US20020173657A1/en not_active Abandoned
-
2003
- 2003-05-20 US US10/441,708 patent/US20040049031A1/en not_active Abandoned
-
2005
- 2005-03-30 US US11/093,701 patent/US20050171152A1/en not_active Abandoned
-
2006
- 2006-04-28 US US11/413,932 patent/US20060189809A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69814862D1 (de) | Verfahren zur herstellung von pyridinderivaten | |
| ATE194850T1 (de) | Verfahren zur herstellung von peroxiperfluoropolyxyalkylene | |
| ATE319687T1 (de) | Verfahren zur herstellung von substituierten pyridinen | |
| ATE238302T1 (de) | Verfahren zur herstellung von thiazolidindion- derivaten | |
| ATE353879T1 (de) | Verfahren zur herstellung von chinolinderivaten | |
| DE69716452D1 (de) | Verfahren zur herstellung von beta-amino-alpha-hydroxycarbonsaeure-derivaten | |
| DE69808068D1 (de) | Verfahren zur herstellung von indolderivaten | |
| ATE219056T1 (de) | Verfahren zur herstellung von alpha- bromolactamderivaten | |
| DE69705722D1 (de) | Verfahren zur herstellung von aluminoxanen | |
| ATE198318T1 (de) | Verfahren zur herstellung von n-acetonylbenzamide | |
| ATE225797T1 (de) | Verfahren zur herstellung von oxazaphosphorin-2- aminen | |
| DE69819191D1 (de) | Verfahren zur herstellung von pentafluorethan | |
| DE69928784D1 (de) | Verfahren zur herstellung von oxazolidin-2-on-derivaten | |
| ATE221056T1 (de) | Verfahren zur herstellung von benzisothiazolin-3- onen | |
| DE69733152D1 (de) | Verfahren zur herstellung von tetrazolylbenzopyranen | |
| DE59802764D1 (de) | Verfahren zur herstellung von phosphabenzolverbindungen | |
| DE69900543D1 (de) | Verfahren zur herstellung von 2-aminothiazolcarboxamidderivaten | |
| DE69806759D1 (de) | Verfahren zur herstellung von pentafluorethan | |
| DE60011427D1 (de) | Verfahren zur herstellung von 2-pyridylpiperidin-derivaten | |
| ATE207920T1 (de) | Verfahren zur herstellung von 4h-4-oxo-chinolizin-3-carbonsäure-derivaten | |
| ATE256665T1 (de) | Verfahren zur herstellung von 1-phenylpyrazolin-3-carbonsäure-derivaten | |
| DE59802548D1 (de) | Verfahren zur herstellung von webware | |
| DE59805432D1 (de) | Verfahren zur herstellung von 2-cyclododecyl-1-propanol | |
| ATE273291T1 (de) | Verfahren zur herstellung von chlorbenzoxazolen | |
| ATE237607T1 (de) | Verfahren zur herstellung von 3-ispchromanon |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |