ATE346070T1 - Purinderivate als kinaseinhibitoren - Google Patents

Purinderivate als kinaseinhibitoren

Info

Publication number
ATE346070T1
ATE346070T1 AT03711146T AT03711146T ATE346070T1 AT E346070 T1 ATE346070 T1 AT E346070T1 AT 03711146 T AT03711146 T AT 03711146T AT 03711146 T AT03711146 T AT 03711146T AT E346070 T1 ATE346070 T1 AT E346070T1
Authority
AT
Austria
Prior art keywords
kinase inhibitors
purine derivatives
purine
derivatives
formula
Prior art date
Application number
AT03711146T
Other languages
German (de)
English (en)
Inventor
Joshua Ryan Clayton
Clive Gideon Diefenbacher
Thomas Albert Engler
Kelly Wayne Furness
James Robert Henry
Sushant Malhotra
Angela Lynn Marquart
Johnathan Alexander Mclean
David Mendel
Timothy Paul Burkholder
Yihong Li
Jon Kevin Reel
John Morris Sullivan
Brian Raymond Berridge
Charles Edward Ruegg
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE346070T1 publication Critical patent/ATE346070T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Enzymes And Modification Thereof (AREA)
AT03711146T 2002-03-05 2003-03-04 Purinderivate als kinaseinhibitoren ATE346070T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36224502P 2002-03-05 2002-03-05

Publications (1)

Publication Number Publication Date
ATE346070T1 true ATE346070T1 (de) 2006-12-15

Family

ID=27805149

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03711146T ATE346070T1 (de) 2002-03-05 2003-03-04 Purinderivate als kinaseinhibitoren

Country Status (16)

Country Link
US (4) US7491716B2 (enExample)
EP (1) EP1483265B1 (enExample)
JP (1) JP4414232B2 (enExample)
KR (1) KR100974770B1 (enExample)
CN (1) CN1312154C (enExample)
AT (1) ATE346070T1 (enExample)
AU (1) AU2003215325B8 (enExample)
BR (1) BR0308243B1 (enExample)
CA (1) CA2477967C (enExample)
CY (1) CY1109006T1 (enExample)
DE (1) DE60309848T2 (enExample)
DK (1) DK1483265T3 (enExample)
ES (1) ES2276048T3 (enExample)
IL (2) IL163781A0 (enExample)
PT (1) PT1483265E (enExample)
WO (1) WO2003076442A1 (enExample)

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Also Published As

Publication number Publication date
EP1483265A1 (en) 2004-12-08
DE60309848T2 (de) 2007-05-16
IL163781A (en) 2010-04-15
AU2003215325B8 (en) 2008-10-09
BR0308243B1 (pt) 2014-08-26
IL163781A0 (en) 2005-12-18
JP2005526072A (ja) 2005-09-02
DE60309848D1 (de) 2007-01-04
US8022065B2 (en) 2011-09-20
JP4414232B2 (ja) 2010-02-10
US7491716B2 (en) 2009-02-17
CN1312154C (zh) 2007-04-25
CA2477967C (en) 2010-08-10
PT1483265E (pt) 2007-01-31
AU2003215325B2 (en) 2008-09-18
WO2003076442A1 (en) 2003-09-18
US20090105229A1 (en) 2009-04-23
CY1109006T1 (el) 2014-07-02
CN1639165A (zh) 2005-07-13
BR0308243A (pt) 2005-01-11
KR100974770B1 (ko) 2010-08-06
ES2276048T3 (es) 2007-06-16
US20110207721A1 (en) 2011-08-25
DK1483265T3 (da) 2007-03-19
CA2477967A1 (en) 2003-09-18
US20050090483A1 (en) 2005-04-28
US8058425B2 (en) 2011-11-15
KR20040087338A (ko) 2004-10-13
EP1483265B1 (en) 2006-11-22
AU2003215325A1 (en) 2003-09-22
US20110294792A1 (en) 2011-12-01

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