ATE321874T1 - Rekombinanter viraler dns vektor zur transfektion tierischer zellen - Google Patents
Rekombinanter viraler dns vektor zur transfektion tierischer zellenInfo
- Publication number
- ATE321874T1 ATE321874T1 AT95306498T AT95306498T ATE321874T1 AT E321874 T1 ATE321874 T1 AT E321874T1 AT 95306498 T AT95306498 T AT 95306498T AT 95306498 T AT95306498 T AT 95306498T AT E321874 T1 ATE321874 T1 AT E321874T1
- Authority
- AT
- Austria
- Prior art keywords
- recombinase
- gene
- vector
- foreign gene
- replication
- Prior art date
Links
- 239000013598 vector Substances 0.000 title abstract 3
- 238000001890 transfection Methods 0.000 title 1
- 230000003612 virological effect Effects 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 108020004414 DNA Proteins 0.000 abstract 3
- 108091034057 RNA (poly(A)) Proteins 0.000 abstract 3
- 210000004102 animal cell Anatomy 0.000 abstract 3
- 230000010076 replication Effects 0.000 abstract 3
- 239000013603 viral vector Substances 0.000 abstract 3
- 108020004511 Recombinant DNA Proteins 0.000 abstract 2
- 108010091086 Recombinases Proteins 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 108020004638 Circular DNA Proteins 0.000 abstract 1
- 102000053602 DNA Human genes 0.000 abstract 1
- 208000028782 Hereditary disease Diseases 0.000 abstract 1
- 208000026350 Inborn Genetic disease Diseases 0.000 abstract 1
- 208000024556 Mendelian disease Diseases 0.000 abstract 1
- 102000018120 Recombinases Human genes 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25131294A JP4216350B2 (ja) | 1994-09-19 | 1994-09-19 | 動物細胞感染用の組換えｄｎａウイルスベクター |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE321874T1 true ATE321874T1 (de) | 2006-04-15 |
Family
ID=17220940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95306498T ATE321874T1 (de) | 1994-09-19 | 1995-09-14 | Rekombinanter viraler dns vektor zur transfektion tierischer zellen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5817492A (de) |
| EP (1) | EP0704534B1 (de) |
| JP (1) | JP4216350B2 (de) |
| KR (1) | KR100379654B1 (de) |
| CN (1) | CN1077919C (de) |
| AT (1) | ATE321874T1 (de) |
| AU (1) | AU698250B2 (de) |
| CA (1) | CA2157063C (de) |
| DE (1) | DE69534902T2 (de) |
| NZ (1) | NZ272883A (de) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5919676A (en) * | 1993-06-24 | 1999-07-06 | Advec, Inc. | Adenoviral vector system comprising Cre-loxP recombination |
| US6120764A (en) * | 1993-06-24 | 2000-09-19 | Advec, Inc. | Adenoviruses for control of gene expression |
| US6974694B2 (en) | 1995-06-07 | 2005-12-13 | Advec, Inc. | Adenoviruses for control of gene expression |
| DE19530412A1 (de) * | 1995-08-18 | 1997-02-20 | Harald Von Prof Dr Melchner | Selbst deletierende retrovirale Vektoren für die Gentherapie |
| US5801030A (en) * | 1995-09-01 | 1998-09-01 | Genvec, Inc. | Methods and vectors for site-specific recombination |
| WO1997019181A2 (de) * | 1995-11-24 | 1997-05-29 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin | Virusvektor für den transfer stabiler episome |
| FR2749857B1 (fr) * | 1996-06-12 | 1998-08-14 | Centre Nat Rech Scient | Generation de molecules replicatives in vivo |
| WO1998017801A1 (en) * | 1996-10-18 | 1998-04-30 | Canji, Inc. | METHODS AND COMPOSITIONS FOR DELIVERY AND EXPRESSION OF INTERFERON-α NUCLEIC ACIDS |
| US20030045492A1 (en) * | 1997-08-13 | 2003-03-06 | Tang De-Chu C. | Vaccination by topical application of recombinant vectors |
| US20030125278A1 (en) * | 1997-08-13 | 2003-07-03 | Tang De-Chu C. | Immunization of animals by topical applications of a salmonella-based vector |
| US6348450B1 (en) * | 1997-08-13 | 2002-02-19 | The Uab Research Foundation | Noninvasive genetic immunization, expression products therefrom and uses thereof |
| US6716823B1 (en) | 1997-08-13 | 2004-04-06 | The Uab Research Foundation | Noninvasive genetic immunization, expression products therefrom, and uses thereof |
| US6706693B1 (en) | 1997-08-13 | 2004-03-16 | The Uab Research Foundation | Vaccination by topical application of genetic vectors |
| DE69842019D1 (de) * | 1997-10-16 | 2011-01-05 | Synageva Biopharma Corp | Transgene vögel und proteinproduktion |
| US7098191B2 (en) * | 1997-11-03 | 2006-08-29 | The Arizona Board Of Reagents | Hyperthermic inducible expression vectors for gene therapy and methods of use thereof |
| US6709858B1 (en) * | 1997-11-03 | 2004-03-23 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Hyperthermic inducible expression vectors for gene therapy and methods of use thereof |
| EP1122310A4 (de) * | 1998-10-12 | 2002-11-20 | Sumitomo Pharma | Rekombinase exprimierende zellen |
| AU1128400A (en) | 1998-10-22 | 2000-05-08 | Medical College Of Georgia Institute, Inc. | Long terminal repeat, enhancer, and insulator sequences for use in recombinant vectors |
| WO2000052187A2 (en) * | 1999-03-05 | 2000-09-08 | Merck & Co., Inc. | Enhanced system for construction of adenovirus vectors |
| US6890726B1 (en) | 1999-04-06 | 2005-05-10 | Oklahoma Medical Research Foundation | Method for selecting recombinase variants with altered specificity |
| US20040009936A1 (en) * | 1999-05-03 | 2004-01-15 | Tang De-Chu C. | Vaccine and drug delivery by topical application of vectors and vector extracts |
| WO2002006451A1 (en) * | 2000-07-18 | 2002-01-24 | Uab Research Foundation | Tissue-specific self-inactivating gene therapy vector |
| US7198924B2 (en) | 2000-12-11 | 2007-04-03 | Invitrogen Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites |
| WO2002092786A2 (en) * | 2001-03-26 | 2002-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | A helper dependent adenoviral vector system and methods for using the same |
| WO2003002735A2 (en) * | 2001-06-28 | 2003-01-09 | Phenogene Therapeutiques Inc. | Methods, vectors, cell lines and kits for selecting nucleic acids having a desired feature |
| US7164056B2 (en) * | 2002-05-03 | 2007-01-16 | Pioneer Hi-Bred International, Inc. | Gene targeting using replicating DNA molecules |
| US20050208466A1 (en) * | 2002-06-17 | 2005-09-22 | Nagoya Industrial Science Research Institute | Method of selective isolation or visualization of target cells differentiated from embryonic cells or kit for visualization |
| US20040203133A1 (en) * | 2003-01-07 | 2004-10-14 | Anja Ehrhardt | Helper dependent adenoviral vector system and methods for using the same |
| WO2005007877A2 (en) * | 2003-07-18 | 2005-01-27 | University Of Massachusetts | Regulatable promoters for synthesis of small hairpin rna |
| JP4478775B2 (ja) | 2003-07-31 | 2010-06-09 | 財団法人名古屋産業科学研究所 | 増殖制御型組換えアデノウイルスベクターの効率的な作製方法及びその作製用キット |
| CN1897977A (zh) * | 2003-10-20 | 2007-01-17 | Ns基因公司 | 帕金森氏病的体内基因治疗 |
| EP1697534B1 (de) | 2003-12-01 | 2010-06-02 | Life Technologies Corporation | Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon |
| MX2007010306A (es) * | 2005-02-23 | 2007-09-26 | Uab Research Foundation | Vacunacion mejorada con alquil-glicosido. |
| US20090074733A1 (en) * | 2005-12-09 | 2009-03-19 | Medin Jeffrey A | Thymidylate kinase mutants and uses thereof |
| US20090068158A1 (en) * | 2005-12-09 | 2009-03-12 | Medin Jeffrey A | Thymidylate kinase mutants and uses thereof |
| EP2514823B1 (de) | 2006-03-03 | 2018-05-02 | ProMIS Neurosciences Inc. | Verfahren und Zusammensetzungen zum Behandeln und Erkennen von missgefaltetem SOD 1-herbeigeführte Erkrankungen |
| CA2584494A1 (en) * | 2007-03-27 | 2008-09-27 | Jeffrey A. Medin | Vector encoding therapeutic polypeptide and safety elements to clear transduced cells |
| ES2654303T3 (es) | 2007-05-04 | 2018-02-13 | University Health Network | Inmunoterapia de IL-12 contra el cáncer |
| JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| US8568709B2 (en) * | 2008-03-20 | 2013-10-29 | University Health Network | Thymidylate kinase fusions and uses thereof |
| ES2722198T3 (es) * | 2008-05-02 | 2019-08-08 | Univ Kyoto | Método de reprogramación nuclear |
| US8629334B2 (en) * | 2008-07-16 | 2014-01-14 | University Of Florida Research Foundation, Inc. | Viral-based transient-expression vector system for trees |
| US8779231B2 (en) | 2010-07-07 | 2014-07-15 | Snu R&Db Foundation | Transgenic mouse for expressing human ferritin in tissue non-specific manner and use thereof |
| WO2014078819A2 (en) | 2012-11-16 | 2014-05-22 | Transposagen Biopharmaceuticals, Inc. | Site-specific enzymes and methods of use |
| PT3310909T (pt) | 2015-06-17 | 2021-09-09 | Poseida Therapeutics Inc | Composições e métodos para dirigir proteínas para loci específicos no genoma |
| PL3436593T3 (pl) | 2016-03-28 | 2023-03-27 | Ultragenyx Pharmaceutical Inc. | Sposoby inaktywacji termicznej adenowirusów |
| WO2019126578A1 (en) | 2017-12-20 | 2019-06-27 | Poseida Therapeutics, Inc. | Compositions and methods for directing proteins to specific loci in the genome |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1293460C (en) * | 1985-10-07 | 1991-12-24 | Brian Lee Sauer | Site-specific recombination of dna in yeast |
| NZ225470A (en) * | 1987-07-21 | 1990-06-26 | Du Pont | Stable and viable recombinant viral vectors |
| JP2824434B2 (ja) * | 1989-11-28 | 1998-11-11 | 財団法人化学及血清療法研究所 | 新規発現ベクター |
| GB9123929D0 (en) * | 1991-11-11 | 1992-01-02 | Wellcome Found | Novel expression system |
| US5919676A (en) * | 1993-06-24 | 1999-07-06 | Advec, Inc. | Adenoviral vector system comprising Cre-loxP recombination |
| JP3770333B2 (ja) * | 1995-03-15 | 2006-04-26 | 大日本住友製薬株式会社 | 組換えｄｎａウイルスおよびその製造方法 |
| FR2737501B1 (fr) * | 1995-07-31 | 1997-10-24 | Transgene Sa | Nouveaux virus auxiliaires pour la preparation de vecteurs viraux recombinants |
-
1994
- 1994-09-19 JP JP25131294A patent/JP4216350B2/ja not_active Expired - Lifetime
-
1995
- 1995-08-25 AU AU30248/95A patent/AU698250B2/en not_active Expired
- 1995-08-28 CA CA002157063A patent/CA2157063C/en not_active Expired - Lifetime
- 1995-08-29 NZ NZ272883A patent/NZ272883A/en not_active IP Right Cessation
- 1995-08-30 US US08/521,575 patent/US5817492A/en not_active Expired - Lifetime
- 1995-09-13 KR KR1019950029877A patent/KR100379654B1/ko not_active IP Right Cessation
- 1995-09-14 EP EP95306498A patent/EP0704534B1/de not_active Expired - Lifetime
- 1995-09-14 DE DE69534902T patent/DE69534902T2/de not_active Expired - Lifetime
- 1995-09-14 AT AT95306498T patent/ATE321874T1/de not_active IP Right Cessation
- 1995-09-18 CN CN95116291A patent/CN1077919C/zh not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0884589A (ja) | 1996-04-02 |
| CN1077919C (zh) | 2002-01-16 |
| US5817492A (en) | 1998-10-06 |
| NZ272883A (en) | 1996-11-26 |
| CN1132791A (zh) | 1996-10-09 |
| JP4216350B2 (ja) | 2009-01-28 |
| EP0704534A2 (de) | 1996-04-03 |
| EP0704534A3 (de) | 1997-06-11 |
| AU698250B2 (en) | 1998-10-29 |
| DE69534902D1 (de) | 2006-05-18 |
| AU3024895A (en) | 1996-04-04 |
| KR960010864A (ko) | 1996-04-20 |
| EP0704534B1 (de) | 2006-03-29 |
| DE69534902T2 (de) | 2006-11-09 |
| CA2157063C (en) | 2005-11-01 |
| CA2157063A1 (en) | 1996-03-20 |
| KR100379654B1 (ko) | 2004-12-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |