ATE301673T1 - Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand - Google Patents

Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand

Info

Publication number
ATE301673T1
ATE301673T1 AT99972682T AT99972682T ATE301673T1 AT E301673 T1 ATE301673 T1 AT E301673T1 AT 99972682 T AT99972682 T AT 99972682T AT 99972682 T AT99972682 T AT 99972682T AT E301673 T1 ATE301673 T1 AT E301673T1
Authority
AT
Austria
Prior art keywords
protein
known ligand
receptor coupled
rup3 receptor
human rup3
Prior art date
Application number
AT99972682T
Other languages
German (de)
English (en)
Inventor
Ruoping Chen
Huong T Dang
Chen W Liaw
I-Lin Lin
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Application granted granted Critical
Publication of ATE301673T1 publication Critical patent/ATE301673T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99972682T 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand ATE301673T1 (de)

Applications Claiming Priority (24)

Application Number Priority Date Filing Date Title
US10921398P 1998-11-20 1998-11-20
US12041699P 1999-02-16 1999-02-16
US12185299P 1999-02-26 1999-02-26
US12394999P 1999-03-12 1999-03-12
US12394699P 1999-03-12 1999-03-12
US13643699P 1999-05-28 1999-05-28
US13713199P 1999-05-28 1999-05-28
US13643799P 1999-05-28 1999-05-28
US13712799P 1999-05-28 1999-05-28
US13656799P 1999-05-28 1999-05-28
US13643999P 1999-05-28 1999-05-28
US14144899P 1999-06-29 1999-06-29
US15655599P 1999-09-29 1999-09-29
US15663399P 1999-09-29 1999-09-29
US15665399P 1999-09-29 1999-09-29
US15663499P 1999-09-29 1999-09-29
US15728299P 1999-10-01 1999-10-01
US15729399P 1999-10-01 1999-10-01
US15728099P 1999-10-01 1999-10-01
US15728199P 1999-10-01 1999-10-01
US15729499P 1999-10-01 1999-10-01
US41704499A 1999-10-12 1999-10-12
US41676099A 1999-10-12 1999-10-12
PCT/US1999/023687 WO2000031258A2 (en) 1998-11-20 1999-10-13 Human orphan g protein-coupled receptors

Publications (1)

Publication Number Publication Date
ATE301673T1 true ATE301673T1 (de) 2005-08-15

Family

ID=27586698

Family Applications (3)

Application Number Title Priority Date Filing Date
AT99972682T ATE301673T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand
AT07008841T ATE396400T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelte rezeptor rup3 ohne bekannte ligand
AT05003040T ATE366815T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT07008841T ATE396400T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelte rezeptor rup3 ohne bekannte ligand
AT05003040T ATE366815T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand

Country Status (12)

Country Link
EP (8) EP1133559B1 (OSRAM)
JP (5) JP2003534767A (OSRAM)
KR (5) KR100765039B1 (OSRAM)
AT (3) ATE301673T1 (OSRAM)
AU (2) AU770056B2 (OSRAM)
CA (2) CA2645717A1 (OSRAM)
DK (3) DK1584683T3 (OSRAM)
ES (3) ES2243095T3 (OSRAM)
IL (2) IL142538A0 (OSRAM)
NZ (3) NZ537625A (OSRAM)
PT (3) PT1133559E (OSRAM)
WO (1) WO2000031258A2 (OSRAM)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1067183B1 (en) * 1998-03-12 2006-05-17 Astellas Pharma Inc. Novel g protein-coupled receptor proteins
US6071722A (en) * 1998-04-24 2000-06-06 Smithkline Beecham Corporation Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1)
WO1999055733A1 (en) * 1998-04-24 1999-11-04 Smithkline Beecham Corporation Cloning of a novel 7tm receptor axor-2
WO2000026339A2 (en) * 1998-11-03 2000-05-11 Smithkline Beecham Corporation Axor14, a g-protein coupled receptor
US20030017528A1 (en) 1998-11-20 2003-01-23 Ruoping Chen Human orphan G protein-coupled receptors
US7816492B2 (en) 1998-11-20 2010-10-19 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors
USRE42190E1 (en) 1998-11-20 2011-03-01 Arena Pharmaceuticals, Inc. Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors
US6221660B1 (en) 1999-02-22 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding SNORF25 receptor
EP1157038A4 (en) * 1999-02-26 2005-01-19 Smithkline Beecham Corp CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17)
US6620615B1 (en) 1999-04-23 2003-09-16 Curagen Corporation G-protein coupled receptor—encoding nucleic acids
EP1189944A4 (en) * 1999-06-21 2002-09-11 Smithkline Beecham Corp AXOR16, R CEPTEUR COUPL UNE PROT INE G
WO2001004292A1 (en) * 1999-07-13 2001-01-18 Merck Patent Gmbh G-protein coupled receptor and dna sequences thereof
EP1198569A1 (en) * 1999-07-30 2002-04-24 MERCK PATENT GmbH G-protein coupled receptor and dna sequences thereof
CA2382889A1 (en) * 1999-08-27 2001-03-08 Takuya Watanabe Novel g protein-coupled receptor protein and dna thereof
US6998255B1 (en) 1999-09-24 2006-02-14 Solvay Pharmaceuticals B.V. Human G-protein coupled receptor
GB9923177D0 (en) * 1999-09-30 1999-12-01 Pfizer Ltd Novel polypeptide
US6204017B1 (en) * 1999-10-07 2001-03-20 Schering Corporation Polynucleotide encoding a histamine receptor
GB9923890D0 (en) * 1999-10-08 1999-12-08 Pfizer Ltd Novel polypeptide
GB9923893D0 (en) * 1999-10-08 1999-12-08 Pfizer Ltd Novel polypeptide
GB9924960D0 (en) * 1999-10-21 1999-12-22 Pfizer Ltd Novel polypeptide
GB9924956D0 (en) * 1999-10-21 1999-12-22 Pfizer Ltd Novel polypeptide
EP1230361A2 (en) * 1999-10-27 2002-08-14 PHARMACIA & UPJOHN COMPANY G protein-coupled receptors expressed in human brain
ATE375390T1 (de) * 1999-10-29 2007-10-15 Pfizer G-protein-gekoppelter rezeptor-ähnliche proteine
WO2001032864A2 (en) * 1999-11-03 2001-05-10 Merck Patent Gmbh Gpcr-kd5 polypeptides and dna sequences thereof
US6461836B1 (en) * 1999-11-05 2002-10-08 Smithkline Beecham Corporation Molecular cloning of a 7TM receptor (AxOR34) and screening methods thereof
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors
US7029857B1 (en) 1999-12-17 2006-04-18 H. Lundbeck A/S Processes for obtaining compounds employing SNORF72 receptors
WO2001046414A1 (fr) * 1999-12-20 2001-06-28 Banyu Pharmaceutical Co., Ltd. Nouvelle proteine receptrice couplee a la proteine de fixation de guanosine triphosphate, bg26
CA2395416A1 (en) 1999-12-23 2001-06-28 Millennium Pharmaceuticals, Inc. P2y12 receptor
WO2001048189A1 (fr) * 1999-12-28 2001-07-05 Helix Research Institute Nouveaux recepteurs couples a une proteine de liaison au guanosine triphosphate, genes de ces derniers, et production et utilisation de ces derniers
GB0001700D0 (en) * 2000-01-25 2000-03-15 Glaxo Group Ltd Novel protein
ATE370411T1 (de) * 2000-02-04 2007-09-15 Takeda Pharmaceutical Verfahren zum screening
EP1266005B1 (en) * 2000-03-14 2007-03-07 Bayer HealthCare AG Regulation of human lipoxin a4 receptor-like protein
EP1268777A2 (en) * 2000-03-17 2003-01-02 Bayer Aktiengesellschaft Regulation of human leukotriene b 4?-like g protein-coupled receptor
AU2001241156A1 (en) * 2000-03-21 2001-10-03 Yamanouchi Pharmaceutical Co..Ltd. Novel leukotriene b4 receptor
US20030087287A1 (en) * 2000-03-28 2003-05-08 Masanori Miwa Novel g-protein-coupled receptor protein and dna thereof
AU4467301A (en) * 2000-03-31 2001-10-08 Helix Research Institute Novel guanosine triphosphate-binding protein-coupled receptor gprv53, gene thereof and production and use of the same
AU2001248755A1 (en) * 2000-04-12 2001-10-23 Takeda Chemical Industries Ltd. Novel g protein-coupled receptor protein and dna thereof
EP1178110A1 (en) * 2000-08-01 2002-02-06 Aventis Pharma Deutschland GmbH EDG8 receptor for sphingosine 1-phosphate , its preparation and use
AU6744501A (en) * 2000-05-18 2001-11-26 Bayer Aktiengesellschaft Regulation of human dopamine-like g protein-coupled receptor
AU2001276837A1 (en) * 2000-06-23 2002-01-08 Tularik, Inc. Human and mouse g-protein couipled receptors
EP1297139A2 (en) * 2000-06-26 2003-04-02 Akzo Nobel N.V. G-protein coupled receptor org10
AU2001281933A1 (en) * 2000-06-30 2002-01-14 Ingenium Pharmaceuticals Ag Human g protein-coupled receptor igpcr17, and uses therof
US6927041B2 (en) 2000-07-06 2005-08-09 Bayer Corporation Human neuropeptide Y-like G protein-coupled receptor
AU2001279232A1 (en) * 2000-08-09 2002-02-18 Millennium Pharmaceuticals, Inc. Methods for using 14266, a human g protein-coupled receptor
US6790608B2 (en) 2000-09-20 2004-09-14 The Regents Of The University Of California Methods of identifying and ADP-glucose receptor ligand, agonist or antagonist
ATE357457T1 (de) 2000-11-01 2007-04-15 Astellas Pharma Inc Verfahren zum screenen eines plättchenhemmers
AU1252102A (en) * 2000-11-07 2002-05-21 Paradigm Therapeutics Ltd Receptor
CA2429860A1 (en) * 2000-11-27 2002-05-30 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2002044362A1 (en) 2000-12-01 2002-06-06 Yamanouchi Pharmaceutical Co., Ltd. Method of screening remedy for diabetes
US7220580B2 (en) 2000-12-22 2007-05-22 University Of South Florida Sphingosine 1-phosphate receptor gene, sppr
AU2002245182A1 (en) * 2000-12-22 2002-07-08 Mergen Ltd. Methods for identifying g-protein coupled receptors associated with diseases
GB0100782D0 (en) * 2001-01-11 2001-02-21 Glaxo Group Ltd Assay
EP1382678B1 (en) * 2001-04-25 2008-08-27 Astellas Pharma Inc. Guanosine triphosphate-binding protein-coupled recepotr place 6002312 and its gene and production and use of the same
US7419658B2 (en) 2001-07-09 2008-09-02 Euroscreen S.A. Isolated ligand of ChemerinR
US20030096299A1 (en) 2001-07-09 2003-05-22 Valerie Wittamer Natural ligand of G protein coupled receptor ChemR23 and uses thereof
US7858755B2 (en) 2001-07-09 2010-12-28 Euroscreen S.A. Monoclonal antibodies that bind Chemerin polypeptide
US6946244B2 (en) 2001-08-07 2005-09-20 Euroscreen, S.A. Methods of identifying a ligand, an agonist, and an antagonist of G protein coupled receptor GPR86 (P2Y13)
MXPA04009959A (es) 2002-04-12 2004-12-13 Schering Corp Ligandos del receptor acoplado a la proteina g y metodos.
WO2004022086A1 (ja) * 2002-09-02 2004-03-18 Takeda Pharmaceutical Company Limited 副腎皮質ホルモン分泌調節剤
AU2003271149A1 (en) * 2002-10-11 2004-05-04 Yamanouchi Pharmaceutical Co., Ltd. Method of screening remedy for renal failure
US7056685B1 (en) 2002-11-05 2006-06-06 Amgen Inc. Receptor ligands and methods of modulating receptors
US7220734B2 (en) 2002-12-20 2007-05-22 Merck & Co., Inc. 1-(amino)indanes and (1,2-dihydro-3-amino)-benzofurans, benzothiophenes and indoles as Edg receptor agonists
PT1599468E (pt) 2003-01-14 2008-01-14 Arena Pharm Inc Derivados de arilo e heteroarilo 1,2,3.-trissubstituídos comomoduladores do metabolismo, e profilaxia e tratamento dedesordens relacionadas tais como diabetes e hiperglicemia
US7083933B1 (en) 2003-05-09 2006-08-01 Prosidion Limited Methods for identification of modulators of OSGPR116 activity
US7524638B1 (en) 2003-06-27 2009-04-28 Osi Pharmaceuticals, Inc. Methods for identification of modulators of OSGPR114 or OSGPR78 activity, and their use in the treatment of disease
CN1812803A (zh) * 2003-06-27 2006-08-02 唐纳士公司 人类肥大细胞表达的膜蛋白
DOP2006000008A (es) * 2005-01-10 2006-08-31 Arena Pharm Inc Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
GB0508990D0 (en) * 2005-05-03 2005-06-08 Novartis Ag Organic compounds
DK1971862T3 (da) 2006-04-11 2011-02-14 Arena Pharm Inc Fremgangsmåder til anvendelse af GPR119-receptor til identificering af forbindelser anvendelige til øgning af knoglemasse hos en person
US7638541B2 (en) 2006-12-28 2009-12-29 Metabolex Inc. 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
CA2693169C (en) 2007-07-19 2016-01-12 Metabolex, Inc. N-linked heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders
CN101801954B (zh) 2007-09-20 2013-10-09 Irm责任有限公司 作为gpr119活性调节剂的化合物和组合物
EP2146210A1 (en) 2008-04-07 2010-01-20 Arena Pharmaceuticals, Inc. Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditions modulated by PYY
AR077642A1 (es) 2009-07-09 2011-09-14 Arena Pharm Inc Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
CA2775840C (en) 2009-10-01 2018-02-06 Metabolex, Inc. Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts
US8791100B2 (en) 2010-02-02 2014-07-29 Novartis Ag Aryl benzylamine compounds
MX2012011631A (es) 2010-04-06 2013-01-18 Arena Pharm Inc Moduladores del receptor gpr119 y el tratamiento de trastornos relacionados con el mismo.
ES2676209T3 (es) 2010-06-23 2018-07-17 Metabolex Inc. Composiciones de 5-etil-2-{4-[4-(4-tetrazol-1-il-fenoximetil)-tiazol-2-il]-piperidin-1-il}-pirimidina
JP5941916B2 (ja) 2010-09-22 2016-06-29 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｇｐｒ１１９レセプターのモジュレーターおよびそれに関連する障害の処置
US20140018371A1 (en) 2011-04-01 2014-01-16 Arena Pharmaceuticals, Inc. Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
WO2012145361A1 (en) 2011-04-19 2012-10-26 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012145604A1 (en) 2011-04-22 2012-10-26 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012145603A1 (en) 2011-04-22 2012-10-26 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012170702A1 (en) 2011-06-08 2012-12-13 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2013055910A1 (en) 2011-10-12 2013-04-18 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2014074668A1 (en) 2012-11-08 2014-05-15 Arena Pharmaceuticals, Inc. Modulators of gpr119 and the treatment of disorders related thereto
PL3242666T3 (pl) 2015-01-06 2025-02-17 Arena Pharmaceuticals, Inc. Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1
DK3310760T3 (da) 2015-06-22 2022-10-24 Arena Pharm Inc Krystallinsk L-argininsalt af (R)-2-(7-(4-cyclopentyl-3-(trifluormethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3- yl)eddikesyre til anvendelse ved S1P1-receptor-associerede lidelser
EP3493807A1 (en) 2016-08-03 2019-06-12 CymaBay Therapeutics, Inc. Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions
JP2020524181A (ja) 2017-06-19 2020-08-13 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｎａｆｌｄおよびｎａｓｈの治療のための化合物および方法
BR112020024762A2 (pt) 2018-06-06 2021-03-23 Arena Pharmaceuticals, Inc. métodos de tratamento de condições relacionadas ao receptor s1p1

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2237937A1 (en) * 1995-11-15 1997-06-05 Cor Therapeutics, Inc. Novel purinergic receptor
EP0955808A1 (en) * 1996-01-11 1999-11-17 Human Genome Sciences, Inc. Human g-protein coupled receptor
WO1998031810A2 (en) * 1997-01-21 1998-07-23 Schering Corporation Mammalian chemokines; receptors; reagents; uses
US6221627B1 (en) * 1997-02-24 2001-04-24 Smithkline Beecham Corporation cDNA clone HDPB130 that encodes a novel human 7-transmembrane receptor
US5955303A (en) * 1997-03-06 1999-09-21 Incyte Pharmaceuticals, Inc. Human chemokine receptor-like protein
US6555339B1 (en) * 1997-04-14 2003-04-29 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human protein-coupled receptors
US6060272A (en) * 1997-05-07 2000-05-09 Human Genome Sciences, Inc. Human G-protein coupled receptors
EP0899332A3 (en) * 1997-08-15 2000-07-05 Smithkline Beecham Corporation The G-protein coupled receptor HFIAO41
CA2239255A1 (en) * 1997-10-23 1999-04-23 Smithkline Beecham Corporation Cdna clone hneaa81 that encodes a human 7-transmembrane receptor
US5932445A (en) * 1997-11-07 1999-08-03 Incyte Pharmaceuticals, Inc. Signal peptide-containing proteins
ATE362983T1 (de) * 1997-11-11 2007-06-15 Ono Pharmaceutical Co Menschlicher lysophosphatidsäure rezeptor und dessen verwendung
US6207412B1 (en) * 1997-11-13 2001-03-27 The Regents Of The University Of California Identification of a G protein-coupled receptor transcriptionally regulated by protein tyrosine kinase signaling in hematopoietic cells
JP2002504492A (ja) * 1998-02-20 2002-02-12 スミスクライン ビーチャム コーポレーション Ｇタンパク質共役型受容体Ｆｉｓｈｂｏｙ
EP1067183B1 (en) * 1998-03-12 2006-05-17 Astellas Pharma Inc. Novel g protein-coupled receptor proteins
AU3749499A (en) * 1998-04-16 1999-11-01 Millenium Pharmaceuticals, Inc. Novel molecules of the bgckr-related protein family and uses thereof
WO1999055733A1 (en) * 1998-04-24 1999-11-04 Smithkline Beecham Corporation Cloning of a novel 7tm receptor axor-2
SE9801455D0 (sv) * 1998-04-24 1998-04-24 Astra Pharma Inc New receptor
US6071722A (en) * 1998-04-24 2000-06-06 Smithkline Beecham Corporation Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1)
CA2340334A1 (en) * 1998-08-19 2000-03-02 Millenium Pharmaceuticals, Inc. 14274 receptor, a g-protein coupled receptor related to the edg receptor family
WO2000011170A1 (en) * 1998-08-20 2000-03-02 Millennium Pharmaceuticals, Inc. 14400 receptor, a g-protein coupled receptor
EP1107978A1 (en) * 1998-08-24 2001-06-20 Alphagene, Inc. Secreted proteins and polynucleotides encoding them
AU5801099A (en) * 1998-09-02 2000-03-21 Millennium Pharmaceuticals, Inc. 14926 receptor, a novel g-protein coupled receptor
IL142153A0 (en) * 1998-10-13 2002-03-10 Arena Pharm Inc Non-endogenous, constitutively activated human g protein-coupled receptors
EP1123397A2 (en) * 1998-10-16 2001-08-16 Millennium Pharmaceuticals, Inc. G-protein coupled receptors
CA2349759A1 (en) * 1998-11-04 2000-05-11 Chiron Corporation Isolated vshk-1 receptor polypeptides and methods of use thereof
EP1127126B1 (en) * 1998-11-06 2006-10-18 Bayer HealthCare AG G-protein coupled receptors, homologous to ebv-induced gpcr 2 (ebi-2). methods to seek for ligands thereof
US6221660B1 (en) * 1999-02-22 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding SNORF25 receptor
US6689866B1 (en) * 1999-03-09 2004-02-10 Curagen Corporation Polynucleotides and proteins encoded thereby
GB9923177D0 (en) * 1999-09-30 1999-12-01 Pfizer Ltd Novel polypeptide
US6590938B1 (en) * 1999-09-30 2003-07-08 Conexant Systems, Inc. DCT domain conversion of a higher definition signal to lower definition signal

Also Published As

Publication number Publication date
KR20070097564A (ko) 2007-10-04
ES2243095T3 (es) 2005-11-16
PT1133559E (pt) 2005-10-31
KR20010086040A (ko) 2001-09-07
JP2009298791A (ja) 2009-12-24
JP2004267216A (ja) 2004-09-30
KR100926209B1 (ko) 2009-11-09
DK1584683T3 (da) 2007-10-29
EP1584683B1 (en) 2007-07-11
EP2295572A1 (en) 2011-03-16
HK1037675A1 (en) 2002-02-15
ES2308759T3 (es) 2008-12-01
EP2295574A1 (en) 2011-03-16
HK1103763A1 (en) 2007-12-28
WO2000031258A3 (en) 2000-10-05
EP1133559B1 (en) 2005-08-10
JP2003534767A (ja) 2003-11-25
IL142538A0 (en) 2002-03-10
EP1849866B1 (en) 2008-05-21
NZ527622A (en) 2005-03-24
CA2348377A1 (en) 2000-06-02
ES2289610T3 (es) 2008-02-01
ATE366815T1 (de) 2007-08-15
AU2004202147A1 (en) 2004-06-10
IL142538A (en) 2010-11-30
EP1849866A2 (en) 2007-10-31
EP1849866A3 (en) 2007-11-07
EP1580271A2 (en) 2005-09-28
EP1133559A2 (en) 2001-09-19
AU3790400A (en) 2000-06-13
KR100963367B1 (ko) 2010-06-14
PT1849866E (pt) 2008-08-28
EP1780280A1 (en) 2007-05-02
NZ511087A (en) 2004-01-30
CA2348377C (en) 2008-12-02
EP2295573A1 (en) 2011-03-16
EP1580271A3 (en) 2006-01-18
WO2000031258A2 (en) 2000-06-02
JP2008133300A (ja) 2008-06-12
KR20080024233A (ko) 2008-03-17
KR20080104062A (ko) 2008-11-28
JP2007209352A (ja) 2007-08-23
DK1133559T3 (da) 2006-04-10
ATE396400T1 (de) 2008-06-15
CA2645717A1 (en) 2000-06-02
EP1584683A1 (en) 2005-10-12
NZ537625A (en) 2006-08-31
KR100765039B1 (ko) 2007-10-09
KR100926208B1 (ko) 2009-11-09
DK1849866T3 (da) 2008-09-08
PT1584683E (pt) 2007-10-17
AU770056B2 (en) 2004-02-12
KR20080024234A (ko) 2008-03-17

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