IL142153A0 - Non-endogenous, constitutively activated human g protein-coupled receptors - Google Patents
Non-endogenous, constitutively activated human g protein-coupled receptorsInfo
- Publication number
- IL142153A0 IL142153A0 IL14215399A IL14215399A IL142153A0 IL 142153 A0 IL142153 A0 IL 142153A0 IL 14215399 A IL14215399 A IL 14215399A IL 14215399 A IL14215399 A IL 14215399A IL 142153 A0 IL142153 A0 IL 142153A0
- Authority
- IL
- Israel
- Prior art keywords
- endogenous
- protein
- coupled receptors
- activated human
- constitutively activated
- Prior art date
Links
- 101000887490 Homo sapiens Guanine nucleotide-binding protein G(z) subunit alpha Proteins 0.000 title 1
- 102000052301 human GNAZ Human genes 0.000 title 1
- 102000005962 receptors Human genes 0.000 title 1
- 108020003175 receptors Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Plant Pathology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (33)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/170,496 US6555339B1 (en) | 1997-04-14 | 1998-10-13 | Non-endogenous, constitutively activated human protein-coupled receptors |
| US10802998P | 1998-11-12 | 1998-11-12 | |
| US10921398P | 1998-11-20 | 1998-11-20 | |
| US11006098P | 1998-11-27 | 1998-11-27 | |
| US12041699P | 1999-02-16 | 1999-02-16 | |
| US12185299P | 1999-02-26 | 1999-02-26 | |
| US12394699P | 1999-03-12 | 1999-03-12 | |
| US12394499P | 1999-03-12 | 1999-03-12 | |
| US12395199P | 1999-03-12 | 1999-03-12 | |
| US12394599P | 1999-03-12 | 1999-03-12 | |
| US12394999P | 1999-03-12 | 1999-03-12 | |
| US12394899P | 1999-03-12 | 1999-03-12 | |
| US13643799P | 1999-05-28 | 1999-05-28 | |
| US13713199P | 1999-05-28 | 1999-05-28 | |
| US13656799P | 1999-05-28 | 1999-05-28 | |
| US13643699P | 1999-05-28 | 1999-05-28 | |
| US13712799P | 1999-05-28 | 1999-05-28 | |
| US13643999P | 1999-05-28 | 1999-05-28 | |
| US14144899P | 1999-06-29 | 1999-06-29 | |
| US15111499P | 1999-08-27 | 1999-08-27 | |
| US15252499P | 1999-09-03 | 1999-09-03 | |
| US15663499P | 1999-09-29 | 1999-09-29 | |
| US15663399P | 1999-09-29 | 1999-09-29 | |
| US15665399P | 1999-09-29 | 1999-09-29 | |
| US15655599P | 1999-09-29 | 1999-09-29 | |
| US15728099P | 1999-10-01 | 1999-10-01 | |
| US15728299P | 1999-10-01 | 1999-10-01 | |
| US15728199P | 1999-10-01 | 1999-10-01 | |
| US15729399P | 1999-10-01 | 1999-10-01 | |
| US15729499P | 1999-10-01 | 1999-10-01 | |
| US41676099A | 1999-10-12 | 1999-10-12 | |
| US41704499A | 1999-10-12 | 1999-10-12 | |
| PCT/US1999/024065 WO2000022131A2 (en) | 1998-10-13 | 1999-10-13 | Non-endogenous, constitutively activated human g protein-coupled receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL142153A0 true IL142153A0 (en) | 2002-03-10 |
Family
ID=27586908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14215399A IL142153A0 (en) | 1998-10-13 | 1999-10-13 | Non-endogenous, constitutively activated human g protein-coupled receptors |
Country Status (5)
| Country | Link |
|---|---|
| KR (1) | KR20010080882A (en) |
| CA (1) | CA2348688A1 (en) |
| IL (1) | IL142153A0 (en) |
| NZ (1) | NZ510712A (en) |
| WO (1) | WO2000022131A2 (en) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7119190B2 (en) | 1997-04-14 | 2006-10-10 | Arena Pharmaceuticals, Inc. | Endogenous and non-endogenous versions of human G protein-coupled receptors |
| US6555339B1 (en) | 1997-04-14 | 2003-04-29 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human protein-coupled receptors |
| WO1999024569A1 (en) * | 1997-11-11 | 1999-05-20 | Ono Pharmaceutical Co., Ltd. | Human lysophosphatidic acid receptor and use thereof |
| ES2300074T3 (en) | 1998-03-12 | 2008-06-01 | Astellas Pharma Inc. | NEW PROTEINS OF RECEPTORS COPULATED TO PROTEINA G. |
| US7094593B1 (en) | 1998-09-01 | 2006-08-22 | Basf Aktiengesellschaft | Method for improving the function of heterologous G protein-coupled receptors |
| JP2004500013A (en) * | 1998-10-16 | 2004-01-08 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | Novel G protein-coupled receptor |
| WO2000026339A2 (en) * | 1998-11-03 | 2000-05-11 | Smithkline Beecham Corporation | Axor14, a g-protein coupled receptor |
| US7816492B2 (en) | 1998-11-20 | 2010-10-19 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors |
| KR20080104062A (en) * | 1998-11-20 | 2008-11-28 | 아레나 파마슈티칼스, 인크. | Human Orphan G Protein Coupling Receptors |
| US20030017528A1 (en) | 1998-11-20 | 2003-01-23 | Ruoping Chen | Human orphan G protein-coupled receptors |
| USRE42190E1 (en) | 1998-11-20 | 2011-03-01 | Arena Pharmaceuticals, Inc. | Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors |
| US6221660B1 (en) | 1999-02-22 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
| EP1189944A4 (en) * | 1999-06-21 | 2002-09-11 | Smithkline Beecham Corp | G-PROTEIN COUPLED RECEPTOR AXOR16 |
| EP1198569A1 (en) * | 1999-07-30 | 2002-04-24 | MERCK PATENT GmbH | G-protein coupled receptor and dna sequences thereof |
| CA2391868A1 (en) * | 1999-08-27 | 2001-03-08 | Takeda Chemical Industries, Ltd. | Novel g protein-coupled receptor protein and dna thereof |
| AU6727800A (en) * | 1999-08-27 | 2001-03-26 | Takeda Chemical Industries Ltd. | Novel g protein-coupled receptor protein and dna thereof |
| JP2003225088A (en) * | 1999-09-10 | 2003-08-12 | Meiji Seika Kaisha Ltd | Human leukotriene B4 second receptor and DNA encoding the same |
| WO2001025269A2 (en) * | 1999-09-24 | 2001-04-12 | Solvay Pharmaceuticals B.V. | Human g-protein coupled receptor |
| US6998255B1 (en) | 1999-09-24 | 2006-02-14 | Solvay Pharmaceuticals B.V. | Human G-protein coupled receptor |
| GB9923177D0 (en) * | 1999-09-30 | 1999-12-01 | Pfizer Ltd | Novel polypeptide |
| GB9923893D0 (en) * | 1999-10-08 | 1999-12-08 | Pfizer Ltd | Novel polypeptide |
| GB9923890D0 (en) * | 1999-10-08 | 1999-12-08 | Pfizer Ltd | Novel polypeptide |
| GB9923888D0 (en) | 1999-10-08 | 1999-12-08 | Pfizer Ltd | Novel polypeptide |
| GB9924960D0 (en) * | 1999-10-21 | 1999-12-22 | Pfizer Ltd | Novel polypeptide |
| CA2386509A1 (en) * | 1999-10-27 | 2001-05-03 | Pharmacia & Upjohn Company | G protein-coupled receptors expressed in human brain |
| ATE375390T1 (en) * | 1999-10-29 | 2007-10-15 | Pfizer | G-PROTEIN-COUPLED RECEPTOR-LIKE PROTEINS |
| WO2001032865A1 (en) * | 1999-11-03 | 2001-05-10 | Merck Patent Gmbh | Human gpr27-like g-protein coupled receptor polypeptide and polynucleotide sequences |
| AU784543B2 (en) * | 1999-11-16 | 2006-04-27 | Pharmacia & Upjohn Company | Novel G protein-coupled receptors |
| NZ531722A (en) * | 1999-11-17 | 2006-06-30 | Arena Pharm Inc | Endogenous and non-endogenous versions of human G protein-coupled receptors |
| US7029857B1 (en) | 1999-12-17 | 2006-04-18 | H. Lundbeck A/S | Processes for obtaining compounds employing SNORF72 receptors |
| WO2001046414A1 (en) * | 1999-12-20 | 2001-06-28 | Banyu Pharmaceutical Co., Ltd. | Novel guanosine triphosphate-binding protein-coupled receptor protein, bg26 |
| AU2288601A (en) | 1999-12-23 | 2001-07-03 | Millennium Pharmaceuticals, Inc. | P2Y12 receptor |
| GB0001700D0 (en) * | 2000-01-25 | 2000-03-15 | Glaxo Group Ltd | Novel protein |
| AU3222701A (en) | 2000-02-04 | 2001-08-14 | Takeda Chemical Industries Ltd. | Screening method |
| ATE356208T1 (en) * | 2000-03-14 | 2007-03-15 | Bayer Healthcare Ag | REGULATION OF HUMAN LIPOXIN A4 RECEPTOR-LIKE PROTEIN |
| AU3930201A (en) * | 2000-03-17 | 2001-09-24 | Bayer Aktiengesellschaft | Regulation of human leukotriene B4-like G protein-coupled receptor |
| US20030077709A1 (en) * | 2000-03-21 | 2003-04-24 | Masazumi Kamohara | Novel leukotriene B4 receptor |
| WO2001073021A1 (en) * | 2000-03-28 | 2001-10-04 | Takeda Chemical Industries, Ltd. | Novel g protein-coupled receptor protein and dna thereof |
| WO2001073023A1 (en) * | 2000-03-31 | 2001-10-04 | Helix Research Institute | Novel guanosine triphosphate-binding protein-coupled receptor gprv53, gene thereof and production and use of the same |
| WO2001077326A1 (en) * | 2000-04-12 | 2001-10-18 | Takeda Chemical Industries, Ltd. | Novel g protein-coupled receptor protein and dna thereof |
| EP1178110A1 (en) * | 2000-08-01 | 2002-02-06 | Aventis Pharma Deutschland GmbH | EDG8 receptor for sphingosine 1-phosphate , its preparation and use |
| US7163799B2 (en) | 2000-04-27 | 2007-01-16 | Merck & Co., Inc. | Neuromedin U receptor NMUR2 and nucleotides encoding it |
| AU2001259513A1 (en) * | 2000-05-05 | 2001-11-20 | Wyeth | Human histamine h4 receptor |
| EP1282645A2 (en) * | 2000-05-08 | 2003-02-12 | PHARMACIA & UPJOHN COMPANY | G protein-coupled receptors |
| US20030148451A1 (en) * | 2000-05-09 | 2003-08-07 | Kevin Bacon | Endothelial differntiation gene 6-like g protein coupled receptor |
| AU2001269013A1 (en) * | 2000-05-18 | 2001-11-26 | Bayer Aktiengesellschaft | Human galanin receptor-like g protein coupled receptor |
| ATE348162T1 (en) * | 2000-05-18 | 2007-01-15 | Bayer Healthcare Ag | REGULATION OF A HUMAN DOPAMINE-LIKE G-PROTEIN COUPLED RECEPTOR. |
| CA2408134A1 (en) * | 2000-05-18 | 2001-11-22 | Incyte Genomics, Inc. | G-protein coupled receptors |
| CA2410734A1 (en) | 2000-05-31 | 2001-12-06 | Ortho-Mcneil Pharmaceutical, Inc. | Dnas encoding mammalian histamine receptor of the h4 subtype |
| AU2001276837A1 (en) * | 2000-06-23 | 2002-01-08 | Tularik, Inc. | Human and mouse g-protein couipled receptors |
| AU2001281933A1 (en) * | 2000-06-30 | 2002-01-14 | Ingenium Pharmaceuticals Ag | Human g protein-coupled receptor igpcr17, and uses therof |
| US6927041B2 (en) | 2000-07-06 | 2005-08-09 | Bayer Corporation | Human neuropeptide Y-like G protein-coupled receptor |
| US7462457B2 (en) * | 2000-08-30 | 2008-12-09 | Johns Hopkins University School Of Medicine | Identification of activated receptors and ion channels |
| AU2000276780A1 (en) * | 2000-10-02 | 2001-04-23 | Biofocus Discovery Limited | Cellular receptor mutations predicted by multiple-sequence-allignment |
| DE60127435T2 (en) * | 2000-11-01 | 2007-11-29 | Astellas Pharma Inc. | METHOD FOR SCREENING A PLATFORM HEMMERS |
| CA2426037A1 (en) * | 2000-11-07 | 2002-05-16 | Paradigm Therapeutics Limited | A "bach" g protein coupled receptor polypeptide and polynucleotide encoding this receptor |
| DE60125227T2 (en) | 2000-12-01 | 2007-09-20 | Astellas Pharma Inc. | METHOD FOR SCREENING DIABETES HEALING METHODS |
| AU2002222681A1 (en) * | 2000-12-19 | 2002-07-01 | Takeda Chemical Industries Ltd. | Novel transmembrane receptor-like proteins and dnas thereof |
| US7157244B2 (en) | 2001-01-17 | 2007-01-02 | Schering Corporation | Adenosine receptor |
| WO2002088355A1 (en) * | 2001-04-25 | 2002-11-07 | Fujisawa Pharmaceutical Co., Ltd. | Novel guanosine triphosphate-binding protein-coupled recepotr place 6002312 and its gene and production and use of the same |
| US6919176B2 (en) | 2001-05-07 | 2005-07-19 | Amgen Inc. | Polypeptides and nucleic acids associated with cancer |
| AU2002310326A1 (en) * | 2001-06-05 | 2002-12-23 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated versions of plant g protein-coupled receptor: gcr1 |
| US6902902B2 (en) | 2001-11-27 | 2005-06-07 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders |
| WO2003087134A2 (en) | 2002-04-12 | 2003-10-23 | Schering Corporation | G-protein coupled receptor ligands and methods |
| WO2003102159A2 (en) * | 2002-06-04 | 2003-12-11 | Curagen Corporation | Novel proteins and nucleic acids encoding same |
| WO2004022086A1 (en) * | 2002-09-02 | 2004-03-18 | Takeda Pharmaceutical Company Limited | Adrenocortical hormone secretion controller |
| WO2004033687A1 (en) * | 2002-10-11 | 2004-04-22 | Yamanouchi Pharmaceutical Co., Ltd. | Method of screening remedy for renal failure |
| US7056685B1 (en) | 2002-11-05 | 2006-06-06 | Amgen Inc. | Receptor ligands and methods of modulating receptors |
| WO2004060282A2 (en) * | 2002-12-19 | 2004-07-22 | Synaptic Pharmaceutical Corporation | Uses of the snorf207 receptor |
| US7083933B1 (en) | 2003-05-09 | 2006-08-01 | Prosidion Limited | Methods for identification of modulators of OSGPR116 activity |
| US8791100B2 (en) | 2010-02-02 | 2014-07-29 | Novartis Ag | Aryl benzylamine compounds |
| EP3538550A1 (en) | 2016-11-10 | 2019-09-18 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Or10h1 modulators and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4442930B2 (en) * | 1995-12-11 | 2010-03-31 | タフツ メディカル センター インコーポレイテッド | Assay methods for peptide hormone receptor ligands and uses thereof |
| US6255089B1 (en) * | 1997-02-27 | 2001-07-03 | Albany Medical College | Constitutively activated serotonin receptors |
| WO1999024569A1 (en) * | 1997-11-11 | 1999-05-20 | Ono Pharmaceutical Co., Ltd. | Human lysophosphatidic acid receptor and use thereof |
-
1999
- 1999-10-13 WO PCT/US1999/024065 patent/WO2000022131A2/en not_active Ceased
- 1999-10-13 NZ NZ510712A patent/NZ510712A/en not_active IP Right Cessation
- 1999-10-13 KR KR1020017004630A patent/KR20010080882A/en not_active Ceased
- 1999-10-13 CA CA002348688A patent/CA2348688A1/en not_active Abandoned
- 1999-10-13 IL IL14215399A patent/IL142153A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000022131A3 (en) | 2001-02-22 |
| CA2348688A1 (en) | 2000-04-20 |
| NZ510712A (en) | 2004-11-26 |
| KR20010080882A (en) | 2001-08-25 |
| WO2000022131A2 (en) | 2000-04-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL142153A0 (en) | Non-endogenous, constitutively activated human g protein-coupled receptors | |
| IL152136A0 (en) | Non-endogenous, constitutively activated known g protein-coupled receptors | |
| IL149111A0 (en) | Small molecule modulators of non-endogenous, constitutively activated human serotonin receptors | |
| PL352232A1 (en) | Il-8 receptor antagonists | |
| IL146151A0 (en) | Human-g-protein receptor | |
| IL145762A0 (en) | Il-8 receptor antagonists | |
| IL146046A0 (en) | Il-8 receptor antagonists | |
| AU2001240097A1 (en) | G protein-coupled receptors | |
| ZA200109627B (en) | IL-8 receptor antagonists. | |
| EP1183386A4 (en) | Tm4sf receptors | |
| AU2001249922A1 (en) | G protein-coupled receptors | |
| IL142362A0 (en) | Ureidopiperidine derivatives as selective human nk3 receptor antagonists | |
| AU2574801A (en) | Selective iGLUR5 receptor antagonists | |
| EP1194143A4 (en) | Il-8 receptor antagonists | |
| HK1042511A1 (en) | Non-endogenous, constitutively activated human g protein-coupled receptors | |
| AU2001259322A1 (en) | G protein-coupled receptors | |
| AU2001238682A1 (en) | Human g protein-coupled receptors | |
| EP1100813A4 (en) | HUMAN BOMBESIN RECEPTOR SUBTYPE-3sb | |
| EP1185270A4 (en) | Il-8 receptor antagonists | |
| AU4551401A (en) | Novel g protein-coupled receptors | |
| AU4992301A (en) | Novel g protein-coupled receptors | |
| AU2001263346A1 (en) | G protein-coupled receptors | |
| AU5961201A (en) | Novel g protein-coupled receptors | |
| IL160446A0 (en) | Endogenous constitutively activated g protein-coupled orphan receptors | |
| ZA200110203B (en) | IL-8 receptor antagonists. |