ATE212055T1 - Östrogen-rezeptor - Google Patents

Östrogen-rezeptor

Info

Publication number
ATE212055T1
ATE212055T1 AT97200903T AT97200903T ATE212055T1 AT E212055 T1 ATE212055 T1 AT E212055T1 AT 97200903 T AT97200903 T AT 97200903T AT 97200903 T AT97200903 T AT 97200903T AT E212055 T1 ATE212055 T1 AT E212055T1
Authority
AT
Austria
Prior art keywords
estrogen receptor
receptors
relates
present
dna encoding
Prior art date
Application number
AT97200903T
Other languages
English (en)
Inventor
Sietse Mosselman
Rein Dijkema
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26142641&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE212055(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE212055T1 publication Critical patent/ATE212055T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/723—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
AT97200903T 1996-03-26 1997-03-25 Östrogen-rezeptor ATE212055T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96200820 1996-03-26
EP96203284 1996-11-11

Publications (1)

Publication Number Publication Date
ATE212055T1 true ATE212055T1 (de) 2002-02-15

Family

ID=26142641

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97200903T ATE212055T1 (de) 1996-03-26 1997-03-25 Östrogen-rezeptor

Country Status (12)

Country Link
US (3) US7060490B1 (de)
EP (2) EP1162264A3 (de)
JP (1) JPH104986A (de)
KR (1) KR19980041692A (de)
AT (1) ATE212055T1 (de)
AU (1) AU715812B2 (de)
CA (1) CA2200423C (de)
DE (2) DE69709561T2 (de)
DK (1) DK0798378T3 (de)
ES (1) ES2123482T3 (de)
GR (1) GR980300076T1 (de)
HU (1) HU221411B1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0792292T4 (da) * 1995-09-08 2009-07-20 Karobio Ab Orphan-receptor
US7157568B1 (en) 1997-08-05 2007-01-02 American Home Products Corporation Human estrogen receptor-β
CA2302629C (en) * 1997-09-08 2001-02-20 Merck & Co., Inc. Estrogen receptor
US6222015B1 (en) 1997-09-08 2001-04-24 Merck & Co., Inc. Estrogen receptor
DE19839115A1 (de) * 1998-08-27 2000-03-09 Ihf Inst Fuer Hormon Und Fortp Klonierung und Expression von Rinder Estrogenrezeptor-beta
DE19855013C2 (de) 1998-11-20 2001-09-13 Schering Ag Androgen- und Progesteron-Rezeptor bindendes Hormon Response Element
AU1967300A (en) 1998-11-20 2000-06-13 Akzo Nobel N.V. Estrogenic estra-1,3,5(10)-trienes with differential effects on the alpha and beta estrogen receptors, having a linear hydrocarbon chain of from 5-9 carbon atoms in position 11
ES2204613T3 (es) * 1999-04-06 2004-05-01 Akzo Nobel N.V. Androgenos 7-alfa alquilo oralmente activos.
WO2001064665A1 (en) 2000-03-01 2001-09-07 Akzo Nobel N.V. Chroman derivatives as estrogenic compounds
US20040033600A1 (en) 2001-03-21 2004-02-19 Palli Subba Reddy Ecdysone receptor-based inducible gene expression system
AU2001249315A1 (en) * 2000-03-22 2001-10-03 Rheogene, Inc. Ecdysone receptor-based inducible gene expression system
TWI225068B (en) 2000-06-06 2004-12-11 Akzo Nobel Nv Anellated steroid compounds having contraceptive and anti-osteoporosis activity
US8105825B2 (en) 2000-10-03 2012-01-31 Intrexon Corporation Multiple inducible gene regulation system
JP4328094B2 (ja) 2001-02-20 2009-09-09 イントレクソン・コーポレイション 新規置換突然変異体受容体および核受容体−ベースの誘導性遺伝子発現システムにおけるその使用
US9493540B2 (en) 2001-02-20 2016-11-15 Intrexon Corporation Ecdysone receptor/invertebrate retinoid X receptor-based inducible gene expression system
DK1534738T3 (da) 2001-02-20 2012-10-01 Intrexon Corp Nye substitutionsmutantreceptorer og anvendelse heraf i et inducérbart genekpressionssystem på basis af en nuklear receptor
WO2002066614A2 (en) 2001-02-20 2002-08-29 Rheogene Holdings, Inc. Chimeric retinoid x receptors and their use in a novel ecdysone receptor-based inducible gene expression system
AU2002333682A1 (en) * 2001-08-02 2003-02-17 Gencell S.A. Inducible expression systems employing ppar transcriptional activators
EP1288303A1 (de) * 2001-08-23 2003-03-05 Aventis Pharma S.A. Induzierbare Expressionssysteme unter Verwendung von PPAR Transkriptionsaktivatoren
EP1436394A4 (de) 2001-09-26 2004-12-29 Rheo Gene Holdings Inc Zikaden-ecdyson-rezeptor-nukleinsäuren, -polypeptide und ihre verwendungen
AU2002327787A1 (en) * 2001-09-28 2003-04-07 Gordon L. Hager Glucocorticoid receptor nuclear translocation domain
TW200304371A (en) 2002-02-22 2003-10-01 Akzo Nobel Nv Substituted 10-ary1-11H-benzo [b] fluorenes and 7-ary1-5, 6-dihydro-benz [a] anthracenes for selective effects on estrogen receptors
US7674783B2 (en) 2002-11-22 2010-03-09 Dimera Inc. Estrogen beta receptor agonists to prevent or reduce the severity of cardiovascular disease
US7304161B2 (en) 2003-02-10 2007-12-04 Intrexon Corporation Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex
US7456315B2 (en) 2003-02-28 2008-11-25 Intrexon Corporation Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
US7935510B2 (en) 2004-04-30 2011-05-03 Intrexon Corporation Mutant receptors and their use in a nuclear receptor-based inducible gene expression system
UA89964C2 (ru) 2004-09-08 2010-03-25 Н.В. Органон 15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ
RU2637946C2 (ru) 2013-03-15 2017-12-08 Интрексон Корпорейшн Борсодержащие диацилгидразины
EP3194359B1 (de) 2014-09-17 2020-04-08 Intrexon Corporation Borhaltige diacylhydrazinverbindungen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63502397A (ja) * 1986-02-20 1988-09-14 カロビオ　エービー ステロイドレセプタ−タンパクの真核細胞における発現
US5217867A (en) * 1988-11-30 1993-06-08 The Salk Institute For Biological Studies Receptors: their identification, characterization, preparation and use
FR2649994A1 (fr) * 1989-06-30 1991-01-25 Aderegem Procede d'obtention d'un recepteur humain natif sauvage des oestrogenes et ses applications
WO1992008133A1 (en) * 1990-10-29 1992-05-14 Dekalb Plant Genetics Isolation of biological materials using magnetic particles
EP0609240B1 (de) * 1991-09-17 2002-04-03 The Salk Institute For Biological Studies Rezeptoren der steroid/thyroid superfamilie von rezeptoren
DK0792292T4 (da) * 1995-09-08 2009-07-20 Karobio Ab Orphan-receptor
US7157568B1 (en) * 1997-08-05 2007-01-02 American Home Products Corporation Human estrogen receptor-β

Also Published As

Publication number Publication date
EP1162264A3 (de) 2002-05-15
CA2200423C (en) 2006-12-19
US6713270B1 (en) 2004-03-30
DE798378T1 (de) 1999-03-04
AU715812B2 (en) 2000-02-10
GR980300076T1 (en) 1998-11-30
EP0798378A3 (de) 1997-12-29
EP0798378B1 (de) 2002-01-16
ES2123482T1 (es) 1999-01-16
HUP9700636A2 (hu) 1998-04-28
ES2123482T3 (es) 2002-11-01
US7060490B1 (en) 2006-06-13
JPH104986A (ja) 1998-01-13
AU1652197A (en) 1997-10-02
KR19980041692A (ko) 1998-08-17
HU9700636D0 (en) 1997-05-28
HUP9700636A3 (en) 1999-01-28
HK1001978A1 (en) 1998-07-24
EP0798378A2 (de) 1997-10-01
DE69709561D1 (de) 2002-02-21
CA2200423A1 (en) 1997-09-26
DK0798378T3 (da) 2002-04-29
US6680368B1 (en) 2004-01-20
HU221411B1 (en) 2002-09-28
EP1162264A2 (de) 2001-12-12
DE69709561T2 (de) 2002-08-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee
RZN Patent revoked