ATE212055T1 - Östrogen-rezeptor - Google Patents

Östrogen-rezeptor

Info

Publication number
ATE212055T1
ATE212055T1 AT97200903T AT97200903T ATE212055T1 AT E212055 T1 ATE212055 T1 AT E212055T1 AT 97200903 T AT97200903 T AT 97200903T AT 97200903 T AT97200903 T AT 97200903T AT E212055 T1 ATE212055 T1 AT E212055T1
Authority
AT
Austria
Prior art keywords
estrogen receptor
receptors
relates
present
dna encoding
Prior art date
Application number
AT97200903T
Other languages
English (en)
Inventor
Sietse Mosselman
Rein Dijkema
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26142641&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE212055(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE212055T1 publication Critical patent/ATE212055T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/723—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
AT97200903T 1996-03-26 1997-03-25 Östrogen-rezeptor ATE212055T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96200820 1996-03-26
EP96203284 1996-11-11

Publications (1)

Publication Number Publication Date
ATE212055T1 true ATE212055T1 (de) 2002-02-15

Family

ID=26142641

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97200903T ATE212055T1 (de) 1996-03-26 1997-03-25 Östrogen-rezeptor

Country Status (13)

Country Link
US (3) US7060490B1 (de)
EP (2) EP1162264A3 (de)
JP (1) JPH104986A (de)
KR (1) KR19980041692A (de)
AT (1) ATE212055T1 (de)
AU (1) AU715812B2 (de)
CA (1) CA2200423C (de)
DE (2) DE69709561T2 (de)
DK (1) DK0798378T3 (de)
ES (1) ES2123482T3 (de)
GR (1) GR980300076T1 (de)
HK (1) HK1001978A1 (de)
HU (1) HU221411B1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3131649B2 (ja) * 1995-09-08 2001-02-05 カロ バイオ エービー オーファン レセプター
US7157568B1 (en) * 1997-08-05 2007-01-02 American Home Products Corporation Human estrogen receptor-β
US6222015B1 (en) 1997-09-08 2001-04-24 Merck & Co., Inc. Estrogen receptor
AU747049B2 (en) * 1997-09-08 2002-05-09 Merck Sharp & Dohme Corp. Estrogen receptor
DE19839115A1 (de) * 1998-08-27 2000-03-09 Ihf Inst Fuer Hormon Und Fortp Klonierung und Expression von Rinder Estrogenrezeptor-beta
DE19855013C2 (de) 1998-11-20 2001-09-13 Schering Ag Androgen- und Progesteron-Rezeptor bindendes Hormon Response Element
ATE222922T1 (de) 1998-11-20 2002-09-15 Akzo Nobel Nv Estrogenische estra-1,3,5(10)-trien verbindungen mit verschiedenen wirkungen auf estrogenrezeptor alpha und beta mit einer unverzweigten kohlenwasserstoffkette von 5-9 kohlenstoffatomen in position 11
AU5209600A (en) * 1999-04-06 2000-10-23 Akzo Nobel N.V. Orally active androgens
ATE529419T1 (de) 2000-03-01 2011-11-15 Organon Nv Chromanderivate als estrogene verbindungen
US20040033600A1 (en) 2001-03-21 2004-02-19 Palli Subba Reddy Ecdysone receptor-based inducible gene expression system
WO2001070816A2 (en) * 2000-03-22 2001-09-27 Rohm And Haas Company Ecdysone receptor-based inducible gene expression system
TWI225068B (en) 2000-06-06 2004-12-11 Akzo Nobel Nv Anellated steroid compounds having contraceptive and anti-osteoporosis activity
US8105825B2 (en) 2000-10-03 2012-01-31 Intrexon Corporation Multiple inducible gene regulation system
PT1456346E (pt) 2001-02-20 2012-05-02 Intrexon Corp Novo sistema de expressão de genes induzido baseado no recetor de ecdisona / recetor x retinoide invertebrado
CA2438133C (en) 2001-02-20 2015-01-27 Rheogene, Inc. Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
JP4328094B2 (ja) 2001-02-20 2009-09-09 イントレクソン・コーポレイション 新規置換突然変異体受容体および核受容体−ベースの誘導性遺伝子発現システムにおけるその使用
MXPA03007492A (es) * 2001-02-20 2004-10-15 Rheogene Holdings Inc Receptores de retinoide x quimerico y su uso en un sistema de expresion de gen inducible basado en receptor de ecdisona novedoso.
WO2003012113A2 (en) * 2001-08-02 2003-02-13 Gencell S.A. Inducible expression systems employing ppar transcriptional activators
EP1288303A1 (de) * 2001-08-23 2003-03-05 Aventis Pharma S.A. Induzierbare Expressionssysteme unter Verwendung von PPAR Transkriptionsaktivatoren
CA2459827C (en) 2001-09-26 2013-09-03 Subba Reddy Palli Leafhopper ecdysone receptor nucleic acids, polypeptides, and uses thereof
AU2002327787A1 (en) * 2001-09-28 2003-04-07 Gordon L. Hager Glucocorticoid receptor nuclear translocation domain
TW200304371A (en) 2002-02-22 2003-10-01 Akzo Nobel Nv Substituted 10-ary1-11H-benzo [b] fluorenes and 7-ary1-5, 6-dihydro-benz [a] anthracenes for selective effects on estrogen receptors
US7674783B2 (en) 2002-11-22 2010-03-09 Dimera Inc. Estrogen beta receptor agonists to prevent or reduce the severity of cardiovascular disease
US7304161B2 (en) 2003-02-10 2007-12-04 Intrexon Corporation Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex
US7456315B2 (en) 2003-02-28 2008-11-25 Intrexon Corporation Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
US7935510B2 (en) 2004-04-30 2011-05-03 Intrexon Corporation Mutant receptors and their use in a nuclear receptor-based inducible gene expression system
UA89964C2 (ru) 2004-09-08 2010-03-25 Н.В. Органон 15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ
US9127024B2 (en) 2013-03-15 2015-09-08 Intrexon Corporation Boron-containing diacylhydrazines
EP3194359B1 (de) 2014-09-17 2020-04-08 Intrexon Corporation Borhaltige diacylhydrazinverbindungen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7084787A (en) * 1986-02-20 1987-09-09 Karo Bio Ab Eucaryotic expression of steroid receptor proteins
US5217867A (en) * 1988-11-30 1993-06-08 The Salk Institute For Biological Studies Receptors: their identification, characterization, preparation and use
FR2649994A1 (fr) * 1989-06-30 1991-01-25 Aderegem Procede d'obtention d'un recepteur humain natif sauvage des oestrogenes et ses applications
JPH06510363A (ja) * 1990-10-29 1994-11-17 ディカルブ　プラント　ジェネティクス 磁気性粒子を使用する生物学的材料の単離
WO1993006215A1 (en) * 1991-09-17 1993-04-01 The Salk Institute For Biological Studies Receptor of the thyroid/steroid hormone receptor superfamily
JP3131649B2 (ja) * 1995-09-08 2001-02-05 カロ バイオ エービー オーファン レセプター
US7157568B1 (en) * 1997-08-05 2007-01-02 American Home Products Corporation Human estrogen receptor-β

Also Published As

Publication number Publication date
HU9700636D0 (en) 1997-05-28
GR980300076T1 (en) 1998-11-30
EP0798378A3 (de) 1997-12-29
CA2200423C (en) 2006-12-19
US6680368B1 (en) 2004-01-20
EP1162264A2 (de) 2001-12-12
HUP9700636A3 (en) 1999-01-28
AU715812B2 (en) 2000-02-10
CA2200423A1 (en) 1997-09-26
US6713270B1 (en) 2004-03-30
EP0798378B1 (de) 2002-01-16
US7060490B1 (en) 2006-06-13
ES2123482T3 (es) 2002-11-01
EP0798378A2 (de) 1997-10-01
HU221411B1 (en) 2002-09-28
JPH104986A (ja) 1998-01-13
DE69709561T2 (de) 2002-08-29
DK0798378T3 (da) 2002-04-29
HK1001978A1 (en) 1998-07-24
ES2123482T1 (es) 1999-01-16
EP1162264A3 (de) 2002-05-15
KR19980041692A (ko) 1998-08-17
DE798378T1 (de) 1999-03-04
AU1652197A (en) 1997-10-02
DE69709561D1 (de) 2002-02-21
HUP9700636A2 (hu) 1998-04-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee
RZN Patent revoked