ATE301652T1 - Piperazinderivate als agonisten des melanocortin- rezeptors - Google Patents
Piperazinderivate als agonisten des melanocortin- rezeptorsInfo
- Publication number
- ATE301652T1 ATE301652T1 AT02714719T AT02714719T ATE301652T1 AT E301652 T1 ATE301652 T1 AT E301652T1 AT 02714719 T AT02714719 T AT 02714719T AT 02714719 T AT02714719 T AT 02714719T AT E301652 T1 ATE301652 T1 AT E301652T1
- Authority
- AT
- Austria
- Prior art keywords
- agonists
- melanocortin receptor
- piperazine derivatives
- melanocortin
- obesity
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pregnancy & Childbirth (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Indole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26347101P | 2001-01-23 | 2001-01-23 | |
PCT/US2002/000517 WO2002059108A1 (en) | 2001-01-23 | 2002-01-23 | Melanocortin receptor agonists |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE301652T1 true ATE301652T1 (de) | 2005-08-15 |
Family
ID=23001925
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02701922T ATE302773T1 (de) | 2001-01-23 | 2002-01-23 | Piperazin- und piperidinderivate als agonisten des melanocortin-rezeptors |
AT02714719T ATE301652T1 (de) | 2001-01-23 | 2002-01-23 | Piperazinderivate als agonisten des melanocortin- rezeptors |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02701922T ATE302773T1 (de) | 2001-01-23 | 2002-01-23 | Piperazin- und piperidinderivate als agonisten des melanocortin-rezeptors |
Country Status (8)
Country | Link |
---|---|
US (2) | US7186715B2 (de) |
EP (2) | EP1368340B1 (de) |
JP (2) | JP2004523529A (de) |
AT (2) | ATE302773T1 (de) |
CA (2) | CA2431996A1 (de) |
DE (2) | DE60205465T2 (de) |
ES (2) | ES2247298T3 (de) |
WO (2) | WO2002059108A1 (de) |
Families Citing this family (122)
Publication number | Priority date | Publication date | Assignee | Title |
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SE9904724D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
SE9904723D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
ES2247298T3 (es) | 2001-01-23 | 2006-03-01 | Eli Lilly And Company | Derivados de piperazina y piperidina como agonistas del receptor de melanocortina. |
US7169777B2 (en) | 2001-01-23 | 2007-01-30 | Eli Lilly And Company | Melanocortin receptor agonists |
CA2433025A1 (en) | 2001-01-23 | 2002-08-01 | Chaoyu Xie | Substituted piperidines/piperazines as melanocortin receptor agonists |
EP1363631A4 (de) | 2001-03-02 | 2005-11-16 | Bristol Myers Squibb Co | "verbindungen, die sich als modulatoren von melanocortin-rezeptoren eignen und diese enthaltende pharmazeutische zusammensetzungen" |
US6911447B2 (en) | 2001-04-25 | 2005-06-28 | The Procter & Gamble Company | Melanocortin receptor ligands |
US6977264B2 (en) * | 2001-07-25 | 2005-12-20 | Amgen Inc. | Substituted piperidines and methods of use |
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DE60308996T2 (de) | 2002-01-23 | 2007-05-10 | Eli Lilly And Co., Indianapolis | Melanocortinrezeptoragonisten |
US7026335B2 (en) | 2002-04-30 | 2006-04-11 | The Procter & Gamble Co. | Melanocortin receptor ligands |
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2002
- 2002-01-23 ES ES02701922T patent/ES2247298T3/es not_active Expired - Lifetime
- 2002-01-23 DE DE60205465T patent/DE60205465T2/de not_active Expired - Fee Related
- 2002-01-23 CA CA002431996A patent/CA2431996A1/en not_active Abandoned
- 2002-01-23 ES ES02714719T patent/ES2246390T3/es not_active Expired - Lifetime
- 2002-01-23 AT AT02701922T patent/ATE302773T1/de not_active IP Right Cessation
- 2002-01-23 EP EP02714719A patent/EP1368340B1/de not_active Expired - Lifetime
- 2002-01-23 US US10/466,248 patent/US7186715B2/en not_active Expired - Fee Related
- 2002-01-23 WO PCT/US2002/000517 patent/WO2002059108A1/en active IP Right Grant
- 2002-01-23 CA CA002432985A patent/CA2432985A1/en not_active Abandoned
- 2002-01-23 JP JP2002559410A patent/JP2004523529A/ja active Pending
- 2002-01-23 AT AT02714719T patent/ATE301652T1/de not_active IP Right Cessation
- 2002-01-23 WO PCT/US2002/000515 patent/WO2002059117A1/en active IP Right Grant
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- 2002-01-23 DE DE60205727T patent/DE60205727T2/de not_active Expired - Fee Related
- 2002-01-23 JP JP2002559419A patent/JP2004523530A/ja active Pending
- 2002-01-23 US US10/466,121 patent/US7291619B2/en not_active Expired - Fee Related
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ES2246390T3 (es) | 2006-02-16 |
ES2247298T3 (es) | 2006-03-01 |
WO2002059108A1 (en) | 2002-08-01 |
US7291619B2 (en) | 2007-11-06 |
JP2004523529A (ja) | 2004-08-05 |
ATE302773T1 (de) | 2005-09-15 |
DE60205727D1 (de) | 2005-09-29 |
CA2431996A1 (en) | 2002-08-01 |
EP1370558B1 (de) | 2005-08-24 |
EP1368340B1 (de) | 2005-08-10 |
DE60205465T2 (de) | 2006-04-20 |
EP1368340A1 (de) | 2003-12-10 |
WO2002059117A1 (en) | 2002-08-01 |
US20040092507A1 (en) | 2004-05-13 |
EP1370558A1 (de) | 2003-12-17 |
DE60205465D1 (de) | 2005-09-15 |
JP2004523530A (ja) | 2004-08-05 |
WO2002059108A8 (en) | 2003-11-06 |
CA2432985A1 (en) | 2002-08-01 |
WO2002059117A8 (en) | 2003-11-06 |
US20040082590A1 (en) | 2004-04-29 |
US7186715B2 (en) | 2007-03-06 |
DE60205727T2 (de) | 2006-06-29 |
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