ATE295843T1 - Kontinuierliches verfahren zur herstellung von l- ascorbinsäure - Google Patents

Kontinuierliches verfahren zur herstellung von l- ascorbinsäure

Info

Publication number
ATE295843T1
ATE295843T1 AT01991443T AT01991443T ATE295843T1 AT E295843 T1 ATE295843 T1 AT E295843T1 AT 01991443 T AT01991443 T AT 01991443T AT 01991443 T AT01991443 T AT 01991443T AT E295843 T1 ATE295843 T1 AT E295843T1
Authority
AT
Austria
Prior art keywords
ascorbic acid
separation process
klg
acid
producing
Prior art date
Application number
AT01991443T
Other languages
English (en)
Inventor
Bhaskar Arumugam
Nick Collins
Transtio Macias
Steven Thomas Perri
Jeffery Powell
Chester Sink
Michael Cushman
Original Assignee
Eastman Chem Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eastman Chem Co filed Critical Eastman Chem Co
Application granted granted Critical
Publication of ATE295843T1 publication Critical patent/ATE295843T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62—Three oxygen atoms, e.g. ascorbic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01991443T 2000-12-22 2001-12-21 Kontinuierliches verfahren zur herstellung von l- ascorbinsäure ATE295843T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25799100P 2000-12-22 2000-12-22
PCT/US2001/049609 WO2002051826A1 (en) 2000-12-22 2001-12-21 Continuous process for producing l-ascorbic acid

Publications (1)

Publication Number Publication Date
ATE295843T1 true ATE295843T1 (de) 2005-06-15

Family

ID=22978632

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01991443T ATE295843T1 (de) 2000-12-22 2001-12-21 Kontinuierliches verfahren zur herstellung von l- ascorbinsäure

Country Status (10)

Country Link
US (1) US6610863B2 (de)
EP (1) EP1351949B1 (de)
JP (1) JP2004516318A (de)
CN (1) CN1507440A (de)
AT (1) ATE295843T1 (de)
BR (1) BR0116451A (de)
CA (1) CA2432173A1 (de)
DE (1) DE60110932T2 (de)
MX (1) MXPA03005640A (de)
WO (1) WO2002051826A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10231890B4 (de) * 2002-07-12 2004-07-01 Basf Ag Verfahren zur Abtrennung von Ascorbinsäure aus einem polaren, Ascorbinsäure und 2-Keto-L-gulonsäure enthaltenden Lösungsmittel
US6872314B2 (en) 2003-08-29 2005-03-29 Eastman Chemical Company Dewatering process
US9070850B2 (en) 2007-10-31 2015-06-30 Cree, Inc. Light emitting diode package and method for fabricating same
US8866169B2 (en) * 2007-10-31 2014-10-21 Cree, Inc. LED package with increased feature sizes
CN101397286B (zh) * 2008-11-18 2011-12-21 江苏江山制药有限公司 一种维生素c连续结晶的方法
CA2873791C (en) * 2012-05-23 2016-12-13 Lanzatech New Zealand Limited A fermentation and simulated moving bed process
EP2682168A1 (de) 2012-07-02 2014-01-08 Millipore Corporation Reinigung biologischer Moleküle
CN103254159A (zh) * 2013-01-29 2013-08-21 南京凯通粮食生化研究设计有限公司 一种维生素c生产工艺的改进方法
CN104693160B (zh) * 2015-02-16 2016-10-05 安徽泰格生物技术股份有限公司 一种维生素c的制备方法
CN110407782A (zh) * 2019-08-08 2019-11-05 安徽丰原发酵技术工程研究有限公司 一种以古龙酸为原料转化提取维生素c的色谱方法
CN110372648A (zh) * 2019-08-08 2019-10-25 安徽丰原发酵技术工程研究有限公司 一种以古龙酸盐为原料转化提取维生素c的色谱方法
CN111087373A (zh) * 2019-12-29 2020-05-01 安徽丰原发酵技术工程研究有限公司 一种酸法制备维生素c的方法
CN113788752A (zh) * 2021-10-20 2021-12-14 浙江圣达生物研究院有限公司 用模拟移动床色谱分离发酵液中2-酮基-d-葡萄糖酸的方法
CN114369075B (zh) * 2022-02-14 2023-09-29 河北乐开节能科技股份有限公司 利用2-酮基-l-古龙酸的水溶液一步制备vc结晶的方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2265121A (en) 1933-10-25 1941-12-02 Hoffmann La Roche Process for the manufacture of levoascorbic acid
GB428815A (en) 1933-12-09 1935-05-20 Tadeus Reichstein Process for the manufacture of laevo-ascorbic acid (vitamin-c)
US2491065A (en) 1941-12-01 1949-12-13 Tno Process for producing ascorbic acid from 2-keto-levo-gulonic acid or its derivatives
US2462251A (en) 1945-05-16 1949-02-22 Merck & Co Inc Process for preparing ascorbic acids
CH490368A (fr) * 1968-02-01 1970-05-15 Politechnika Slaska Im Wincent Procédé de production de vitamine C
JPS4815931B1 (de) 1970-10-05 1973-05-18
US4111958A (en) * 1977-06-03 1978-09-05 Pfizer Inc. Ascorbic acid synthesis
DD141832A1 (de) * 1978-10-31 1980-05-21 Joachim Schmidt Verfahren und vorrichtung zur herstellung von l-ascorbinsaeure
DE3621781A1 (de) 1985-07-05 1987-01-15 Takeda Chemical Industries Ltd Verfahren zur reinigung von l-ascorbinsaeure
CN86105960A (zh) 1985-08-09 1987-05-13 鲁布里佐尔公司 在基本无水条件下从2-酮-l-古洛糖酸制备l-抗坏血酸
DE3843389A1 (de) 1988-12-23 1990-06-28 Basf Ag Verfahren zur herstellung von ascorbinsaeure
FR2648136B1 (fr) 1989-06-12 1994-06-17 Rhone Poulenc Sante Procede de preparation de l'acide ascorbique
CH678057A5 (de) 1989-06-26 1991-07-31 Enco Eng Ag Verfahren zur herstellung von natrium- oder kalium-l-ascorbat.
JP3134236B2 (ja) 1992-01-30 2001-02-13 株式会社林原生物化学研究所 α−グリコシル−Ｌ−アスコルビン酸高含有物の製造方法とその製造のための分離システム
JPH08188578A (ja) * 1994-11-11 1996-07-23 Takeda Chem Ind Ltd Ｌ−アスコルビン酸の製造方法
JPH08176133A (ja) * 1994-12-26 1996-07-09 Takeda Chem Ind Ltd Ｌ−アスコルビン酸の精製法
IL115564A (en) 1995-10-11 1999-06-20 Yissum Res Dev Co Process for the recovery of ascorbic acid from an aqueous feed solution
DE19547073C1 (de) 1995-12-16 1996-11-14 Merck Patent Gmbh Verfahren zur Herstellung von Ascorbinsäure
WO1999000178A1 (en) 1997-06-30 1999-01-07 Electrosynthesis Company, Inc. Electrochemical methods for recovery of ascorbic acid
DE19734086C1 (de) 1997-08-07 1998-08-13 Merck Patent Gmbh Verfahren zur Herstellung von L-Ascorbinsäure
DE19904821C1 (de) * 1999-02-05 2000-07-06 Merck Patent Gmbh Verfahren zur Herstellung von L-Ascobinsäure
US5998634A (en) 1999-03-15 1999-12-07 The United States Of America As Represented By The Secretary Of The Interior One-step synthesis of vitamin-C (L-ascorbic acid)
DE19919203A1 (de) 1999-04-28 2000-11-02 Basf Ag Verfahren zur Herstellung von L-Ascorbinsäure

Also Published As

Publication number Publication date
US20020151726A1 (en) 2002-10-17
EP1351949B1 (de) 2005-05-18
JP2004516318A (ja) 2004-06-03
DE60110932D1 (de) 2005-06-23
CA2432173A1 (en) 2002-07-04
DE60110932T2 (de) 2006-01-19
MXPA03005640A (es) 2003-10-06
WO2002051826A1 (en) 2002-07-04
BR0116451A (pt) 2003-09-30
US6610863B2 (en) 2003-08-26
EP1351949A1 (de) 2003-10-15
CN1507440A (zh) 2004-06-23

Similar Documents

Publication Publication Date Title
FI961402A (fi) Menetelmä syklisten esterien tuottamiseksi
ATE295843T1 (de) Kontinuierliches verfahren zur herstellung von l- ascorbinsäure
ATE335718T1 (de) Verfahren zur herstellung von acrylsäure
FI20002886A0 (fi) Kemikaalien talteenotto ja valmistus massan valmistuksen yhteydessä
TR200100701T2 (tr) Anhidro şeker alkollerinin üretimi için sürekli işlem.
ATE391116T1 (de) Verfahren zur herstellung von acrylsäure
ATE260235T1 (de) Verfahren zur herstellung von ameisensäure
ATE327215T1 (de) Kontinuierliches verfahren zur herstellung von milchsäure
DE69119234D1 (de) Verfahren zur herstellung von reiner hydroxyessigsäure
FI955855A0 (fi) Menetelmä ksylitolin tuottamiseksi
DE50100896D1 (de) Kontinuierliches Verfahren zur Herstellung von Acetalen
ATE242190T1 (de) Verfahren zur herstellung von cyclododecatrienen mit rückführung des katalysators
SE7600111L (sv) Sett att framstella flerkerniga aromatiska polyaminer
ATE303074T1 (de) Verfahren zur herstellung von metallformat- ameisensäure-mischungen
NO20023633D0 (no) Fremgangsmåte for tilvirkning av piperonal
DE69601963D1 (de) Verfahren mit hoher Ausbeute zur Herstellung von Harnstoff
MX9708774A (es) Procedimiento para la fabricacion de sal de acido clavulanico.
DE50007399D1 (de) Verfahren zur kontinuierlichen herstellung von glutaraldehyd
DE69602250D1 (de) Verfahren und anlage zur herstellung von harnstoff mit hohem umsatz und niedrigem energieverbrauch
DE69913735D1 (de) Verfahren zu herstellung von 5-(alfa-hydroxyalkyl)benzo-[1,3]dioxolane
ATE303373T1 (de) Verfahren zur herstellung von ascorbinsäure in gegenwart eines sulfits
ATE296280T1 (de) Verfahren zur herstellung von aromatischen aminen
DE69710212D1 (de) Verfahren zur gewinnung von ascorbinsäure
ATE529383T1 (de) Verfahren und vorrichtung zur herstellung von calciumbromid durch flüssig-flüssig extraktion
ATE357429T1 (de) Verfahren zur herstellung von beta- ketonitrilverbindungen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1351949

Country of ref document: EP

REN Ceased due to non-payment of the annual fee