ATE287258T1 - Verfahren zur herstellung von liposomen - Google Patents

Verfahren zur herstellung von liposomen

Info

Publication number
ATE287258T1
ATE287258T1 AT99928051T AT99928051T ATE287258T1 AT E287258 T1 ATE287258 T1 AT E287258T1 AT 99928051 T AT99928051 T AT 99928051T AT 99928051 T AT99928051 T AT 99928051T AT E287258 T1 ATE287258 T1 AT E287258T1
Authority
AT
Austria
Prior art keywords
liposomes
compositions
producing liposomes
regent
pharmaceuticals
Prior art date
Application number
AT99928051T
Other languages
German (de)
English (en)
Inventor
Gregory Gregoriadis
Brahim Zadi
Pramukh Nalaka Jayasekera
Original Assignee
Secr Defence
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Secr Defence filed Critical Secr Defence
Application granted granted Critical
Publication of ATE287258T1 publication Critical patent/ATE287258T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT99928051T 1998-06-18 1999-06-16 Verfahren zur herstellung von liposomen ATE287258T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9813100.6A GB9813100D0 (en) 1998-06-18 1998-06-18 Method of forming liposomes
PCT/GB1999/001911 WO1999065465A1 (en) 1998-06-18 1999-06-16 Method of forming liposomes

Publications (1)

Publication Number Publication Date
ATE287258T1 true ATE287258T1 (de) 2005-02-15

Family

ID=10833946

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99928051T ATE287258T1 (de) 1998-06-18 1999-06-16 Verfahren zur herstellung von liposomen

Country Status (15)

Country Link
US (1) US9675554B1 (enExample)
EP (1) EP1087754B1 (enExample)
JP (1) JP4567882B2 (enExample)
KR (1) KR100658956B1 (enExample)
CN (1) CN1312707A (enExample)
AT (1) ATE287258T1 (enExample)
AU (1) AU749499B2 (enExample)
CA (1) CA2335183A1 (enExample)
DE (1) DE69923315T2 (enExample)
GB (2) GB9813100D0 (enExample)
NO (1) NO20006442L (enExample)
NZ (1) NZ508960A (enExample)
RU (1) RU2216315C2 (enExample)
WO (1) WO1999065465A1 (enExample)
ZA (1) ZA200007507B (enExample)

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WO2002038128A1 (fr) * 2000-11-10 2002-05-16 Japan Science And Technology Corporation Procede de preparation d'une dispersion de microsome
AU3652602A (en) * 2000-11-15 2002-05-27 Us Gov Health & Human Serv Sol-fusin: use of gp64-6his to catalyze membrane fusion
BRPI0105509B8 (pt) 2001-11-05 2021-05-25 Univ Minas Gerais formulações do peptídeo angiotensina-(1-7) usando as ciclodextrinas, lipossomas e o polímero plga
US7285289B2 (en) * 2002-04-12 2007-10-23 Nagy Jon O Nanoparticle vaccines
KR100482355B1 (ko) * 2002-05-02 2005-04-14 주식회사 알로에마임 디팔미토일하이드록시프롤린과 소이이소플라본을 함유한리포좀 또는 나노에멀젼 및 이를 함유한 화장료 조성물 및그 제조방법
SI2108362T1 (sl) * 2002-06-26 2013-08-30 Medigene Ag Kationski nosilni sistem, ki vsebuje taksan
ES2331791T5 (es) 2002-06-26 2016-01-21 Medigene Ag Método de producción de una preparación catiónica de liposomas que comprende un compuesto lipófilo
US20050175683A1 (en) * 2003-10-24 2005-08-11 Yuanpeng Zhang Preparation of lipid particles
KR101462825B1 (ko) 2004-05-03 2014-11-21 헤르메스 바이오사이언스, 인코포레이티드 약물 전달에 유용한 리포좀
ATE454884T1 (de) * 2004-10-18 2010-01-15 Polymun Scient Immunbio Forsch Liposomale zusammensetzung einen wirkstoff zur relaxierung glatter muskulatur enthaltend, die herstellung dieser zusammensetzung und deren therapeutische verwendung
JP2009510032A (ja) 2005-09-30 2009-03-12 リポクセン テクノロジーズ リミテッド 多糖抗原及びタンパク質アジュバントを含む多価リポソームワクチン組成物
RU2300369C1 (ru) * 2005-12-27 2007-06-10 Наталья Ивановна Ларионова Способ получения полиэлектролитных микрочастиц, содержащих инкапсулируемое вещество, чувствительных к изменению состава окружающей среды
EP2492278A1 (en) 2006-09-18 2012-08-29 Compugen Ltd. Antibodies against an agonist of G-protein coupled receptors and its use indiagnosis and therapy
CA2693651A1 (en) 2007-07-12 2009-01-15 Ronen Shemesh Bioactive peptides and method of using same
JP5362998B2 (ja) * 2008-01-10 2013-12-11 第一ファインケミカル株式会社 乾燥リポソーム製剤
US9445975B2 (en) 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
WO2010041255A2 (en) 2008-10-07 2010-04-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Liposomal systems comprising sphingomyelin
EP2184054A1 (en) 2008-11-08 2010-05-12 Lipoxen Technologies Limited Small Interfering RNA Delivery
WO2010140377A1 (ja) 2009-06-04 2010-12-09 独立行政法人産業技術総合研究所 マイコプラズマ感染症用ワクチン
RU2409668C1 (ru) * 2009-09-02 2011-01-20 Александр Анатольевич Ярославов Способ получения иммобилизованных бислойных везикул
KR20110068831A (ko) 2009-12-16 2011-06-22 재단법인 전라남도생물산업진흥재단 리포좀 조성물, 그 제조방법, 및 폐렴 백신으로서의 그 용도
FR2958851B1 (fr) * 2010-04-16 2012-06-29 Xeda International Nouvelles formulations d'ingredient(s) actif(s) d'origine vegetale ou leurs analogues synthetiques ou d'extrait(s) d'origine vegetale les contenant, et de lecithine
BR112013017267B1 (pt) 2011-01-04 2021-06-22 Archivel Farma, Sl Formulação de lipossomas, suspensão e composição farmacêutica
PT2768484T (pt) 2011-10-21 2019-10-28 Jazz Pharmaceuticals Res Llc Lipossomas liofilizados
IN2014MN01594A (enExample) 2012-01-12 2015-05-08 Archivel Farma Sl
EA023079B1 (ru) * 2012-12-24 2016-04-29 Общество С Ограниченной Ответственностью "Технология Лекарств" Способ получения липосомальной формы иринотекана (варианты)
JP6866060B2 (ja) * 2014-10-27 2021-04-28 花王株式会社 精製茶抽出物の製造方法
KR101739208B1 (ko) * 2014-12-30 2017-05-25 (주)셀트리온 표피성장인자와 리포좀의 하이브리드형 다중층 나노구조체 및 그 제조방법
WO2016191700A1 (en) * 2015-05-27 2016-12-01 Nuvox Pharma Llc Treatment of acute complications of sickle cell disease
WO2017049132A1 (en) * 2015-09-18 2017-03-23 DNARx Systems and methods for nucleic acid expression in vivo
ES3036518T3 (en) 2015-10-16 2025-09-19 Ipsen Biopharm Ltd Stabilizing camptothecin pharmaceutical compositions
EP3600428A4 (en) 2017-03-23 2020-08-26 Dnarx SYSTEMS AND METHODS FOR THE EXPRESSION OF NUCLEIC ACIDS IN VIVO
GB201707700D0 (en) 2017-05-12 2017-06-28 Glaxosmithkline Biologicals Sa Dried composition
RU2697802C1 (ru) * 2018-08-23 2019-08-20 Федеральное Государственное Бюджетное Учреждение Науки Институт Биохимической Физики Им. Н.М. Эмануэля Российской Академии Наук (Ибхф Ран) Способ получения магнитных липосом

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US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
EP0208764A4 (en) * 1985-01-11 1987-10-08 Univ California METHOD FOR PRESERVING LIPOSOMES.
CA1256372A (en) * 1985-04-11 1989-06-27 Koichiro Miyazima Process for producing liposome composition
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US5089181A (en) * 1987-02-24 1992-02-18 Vestar, Inc. Method of dehydrating vesicle preparations for long term storage
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JP2780755B2 (ja) * 1987-05-22 1998-07-30 ザ リポソーム カンパニー，インコーポレイテッド プロスタグランジン‐脂質製剤
DE68916439T2 (de) * 1988-10-05 1994-10-20 Vestar Inc Verfahren zur herstellung von liposomen mit verbesserter stabilität während des trocknens.
RU2014071C1 (ru) * 1991-03-26 1994-06-15 Научно-производственный центр медицинской биотехнологии Способ получения липосом, содержащих водорастворимые низкомолекулярные соединения
US5958881A (en) * 1991-04-25 1999-09-28 Korman; Louis Y. Composition containing VIP for injection and a method of enhancing visualization of tissues during medical procedures
WO1993020802A1 (en) * 1992-04-09 1993-10-28 Northwestern University Acoustically reflective liposomes and methods to make and use the same
DK0678017T3 (da) * 1993-11-05 1998-10-19 Amgen Inc Liposomfremstilling og materialeindkapslingsfremgangsmåde
EP0914094A4 (en) * 1996-03-28 2000-03-01 Univ Illinois MATERIALS AND METHOD FOR PRODUCING IMPROVED LIPOSOMAL AGENTS
CA2202103C (en) * 1996-04-11 2007-01-09 Toshiaki Tagawa Method for preparing closed vesicles
JP3693209B2 (ja) * 1996-04-11 2005-09-07 三菱化学株式会社 閉鎖小胞の製造方法
RU2123328C1 (ru) * 1996-04-19 1998-12-20 Государственный научный центр вирусологии и биотехнологии "Вектор" Липосомальное противовирусное лекарственное средство для перорального применения
NZ332666A (en) * 1996-05-08 2000-05-26 Nika Health Products Ltd Cationic virosomes having a positively charged lipid bilayer membrane with an integrated viral fusogenic peptide as genetic transfer systems for use in gene therapy

Also Published As

Publication number Publication date
RU2216315C2 (ru) 2003-11-20
NZ508960A (en) 2002-11-26
CN1312707A (zh) 2001-09-12
NO20006442D0 (no) 2000-12-15
GB2354166B (en) 2003-09-10
NO20006442L (no) 2001-02-15
GB9813100D0 (en) 1998-08-19
KR20010053006A (ko) 2001-06-25
US9675554B1 (en) 2017-06-13
JP2003513003A (ja) 2003-04-08
EP1087754B1 (en) 2005-01-19
KR100658956B1 (ko) 2006-12-21
AU749499B2 (en) 2002-06-27
GB0030767D0 (en) 2001-01-31
EP1087754A1 (en) 2001-04-04
DE69923315D1 (de) 2005-02-24
ZA200007507B (en) 2002-03-14
GB2354166A (en) 2001-03-21
WO1999065465A1 (en) 1999-12-23
CA2335183A1 (en) 1999-12-23
DE69923315T2 (de) 2006-04-06
AU4518099A (en) 2000-01-05
JP4567882B2 (ja) 2010-10-20

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