AU749499B2 - Method of forming liposomes - Google Patents

Method of forming liposomes Download PDF

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Publication number
AU749499B2
AU749499B2 AU45180/99A AU4518099A AU749499B2 AU 749499 B2 AU749499 B2 AU 749499B2 AU 45180/99 A AU45180/99 A AU 45180/99A AU 4518099 A AU4518099 A AU 4518099A AU 749499 B2 AU749499 B2 AU 749499B2
Authority
AU
Australia
Prior art keywords
liposomes
sugar
sucrose
size
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU45180/99A
Other languages
English (en)
Other versions
AU4518099A (en
Inventor
Gregory Gregoriadis
Pramukh Nalaka Jayasekera
Brahim Zadi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UK Secretary of State for Defence
Original Assignee
UK Secretary of State for Defence
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UK Secretary of State for Defence filed Critical UK Secretary of State for Defence
Publication of AU4518099A publication Critical patent/AU4518099A/en
Application granted granted Critical
Publication of AU749499B2 publication Critical patent/AU749499B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU45180/99A 1998-06-18 1999-06-16 Method of forming liposomes Expired AU749499B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9813100.6A GB9813100D0 (en) 1998-06-18 1998-06-18 Method of forming liposomes
GB9813100 1998-06-18
PCT/GB1999/001911 WO1999065465A1 (en) 1998-06-18 1999-06-16 Method of forming liposomes

Publications (2)

Publication Number Publication Date
AU4518099A AU4518099A (en) 2000-01-05
AU749499B2 true AU749499B2 (en) 2002-06-27

Family

ID=10833946

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45180/99A Expired AU749499B2 (en) 1998-06-18 1999-06-16 Method of forming liposomes

Country Status (15)

Country Link
US (1) US9675554B1 (enExample)
EP (1) EP1087754B1 (enExample)
JP (1) JP4567882B2 (enExample)
KR (1) KR100658956B1 (enExample)
CN (1) CN1312707A (enExample)
AT (1) ATE287258T1 (enExample)
AU (1) AU749499B2 (enExample)
CA (1) CA2335183A1 (enExample)
DE (1) DE69923315T2 (enExample)
GB (2) GB9813100D0 (enExample)
NO (1) NO20006442L (enExample)
NZ (1) NZ508960A (enExample)
RU (1) RU2216315C2 (enExample)
WO (1) WO1999065465A1 (enExample)
ZA (1) ZA200007507B (enExample)

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AU3652602A (en) * 2000-11-15 2002-05-27 Us Gov Health & Human Serv Sol-fusin: use of gp64-6his to catalyze membrane fusion
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KR100482355B1 (ko) * 2002-05-02 2005-04-14 주식회사 알로에마임 디팔미토일하이드록시프롤린과 소이이소플라본을 함유한리포좀 또는 나노에멀젼 및 이를 함유한 화장료 조성물 및그 제조방법
SI2108362T1 (sl) * 2002-06-26 2013-08-30 Medigene Ag Kationski nosilni sistem, ki vsebuje taksan
ES2331791T5 (es) 2002-06-26 2016-01-21 Medigene Ag Método de producción de una preparación catiónica de liposomas que comprende un compuesto lipófilo
US20050175683A1 (en) * 2003-10-24 2005-08-11 Yuanpeng Zhang Preparation of lipid particles
KR101462825B1 (ko) 2004-05-03 2014-11-21 헤르메스 바이오사이언스, 인코포레이티드 약물 전달에 유용한 리포좀
ATE454884T1 (de) * 2004-10-18 2010-01-15 Polymun Scient Immunbio Forsch Liposomale zusammensetzung einen wirkstoff zur relaxierung glatter muskulatur enthaltend, die herstellung dieser zusammensetzung und deren therapeutische verwendung
JP2009510032A (ja) 2005-09-30 2009-03-12 リポクセン テクノロジーズ リミテッド 多糖抗原及びタンパク質アジュバントを含む多価リポソームワクチン組成物
RU2300369C1 (ru) * 2005-12-27 2007-06-10 Наталья Ивановна Ларионова Способ получения полиэлектролитных микрочастиц, содержащих инкапсулируемое вещество, чувствительных к изменению состава окружающей среды
EP2492278A1 (en) 2006-09-18 2012-08-29 Compugen Ltd. Antibodies against an agonist of G-protein coupled receptors and its use indiagnosis and therapy
CA2693651A1 (en) 2007-07-12 2009-01-15 Ronen Shemesh Bioactive peptides and method of using same
JP5362998B2 (ja) * 2008-01-10 2013-12-11 第一ファインケミカル株式会社 乾燥リポソーム製剤
US9445975B2 (en) 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
WO2010041255A2 (en) 2008-10-07 2010-04-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Liposomal systems comprising sphingomyelin
EP2184054A1 (en) 2008-11-08 2010-05-12 Lipoxen Technologies Limited Small Interfering RNA Delivery
WO2010140377A1 (ja) 2009-06-04 2010-12-09 独立行政法人産業技術総合研究所 マイコプラズマ感染症用ワクチン
RU2409668C1 (ru) * 2009-09-02 2011-01-20 Александр Анатольевич Ярославов Способ получения иммобилизованных бислойных везикул
KR20110068831A (ko) 2009-12-16 2011-06-22 재단법인 전라남도생물산업진흥재단 리포좀 조성물, 그 제조방법, 및 폐렴 백신으로서의 그 용도
FR2958851B1 (fr) * 2010-04-16 2012-06-29 Xeda International Nouvelles formulations d'ingredient(s) actif(s) d'origine vegetale ou leurs analogues synthetiques ou d'extrait(s) d'origine vegetale les contenant, et de lecithine
BR112013017267B1 (pt) 2011-01-04 2021-06-22 Archivel Farma, Sl Formulação de lipossomas, suspensão e composição farmacêutica
PT2768484T (pt) 2011-10-21 2019-10-28 Jazz Pharmaceuticals Res Llc Lipossomas liofilizados
IN2014MN01594A (enExample) 2012-01-12 2015-05-08 Archivel Farma Sl
EA023079B1 (ru) * 2012-12-24 2016-04-29 Общество С Ограниченной Ответственностью "Технология Лекарств" Способ получения липосомальной формы иринотекана (варианты)
JP6866060B2 (ja) * 2014-10-27 2021-04-28 花王株式会社 精製茶抽出物の製造方法
KR101739208B1 (ko) * 2014-12-30 2017-05-25 (주)셀트리온 표피성장인자와 리포좀의 하이브리드형 다중층 나노구조체 및 그 제조방법
WO2016191700A1 (en) * 2015-05-27 2016-12-01 Nuvox Pharma Llc Treatment of acute complications of sickle cell disease
WO2017049132A1 (en) * 2015-09-18 2017-03-23 DNARx Systems and methods for nucleic acid expression in vivo
ES3036518T3 (en) 2015-10-16 2025-09-19 Ipsen Biopharm Ltd Stabilizing camptothecin pharmaceutical compositions
EP3600428A4 (en) 2017-03-23 2020-08-26 Dnarx SYSTEMS AND METHODS FOR THE EXPRESSION OF NUCLEIC ACIDS IN VIVO
GB201707700D0 (en) 2017-05-12 2017-06-28 Glaxosmithkline Biologicals Sa Dried composition
RU2697802C1 (ru) * 2018-08-23 2019-08-20 Федеральное Государственное Бюджетное Учреждение Науки Институт Биохимической Физики Им. Н.М. Эмануэля Российской Академии Наук (Ибхф Ран) Способ получения магнитных липосом

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883665A (en) * 1985-04-11 1989-11-28 Takeda Chemical Industries, Ltd. Process for producing liposome composition
WO1997035561A1 (en) * 1996-03-28 1997-10-02 The Board Of Trustees Of The University Of Illinois Materials and methods for making improved liposome compositions
EP0800822A2 (en) * 1996-04-11 1997-10-15 Mitsubishi Chemical Corporation Method for preparing closed vesicles by rehydration of dehydrated vesicles

Family Cites Families (16)

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US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
EP0208764A4 (en) * 1985-01-11 1987-10-08 Univ California METHOD FOR PRESERVING LIPOSOMES.
US5094785A (en) * 1986-12-10 1992-03-10 Ciba Corning Diagnostics Corp. Process for stabilizing liposomes
AU612631B2 (en) * 1987-02-24 1991-07-18 Vestar, Inc. Dehydrating vesicule preparations for long-term storage
US5089181A (en) * 1987-02-24 1992-02-18 Vestar, Inc. Method of dehydrating vesicle preparations for long term storage
MX9203808A (es) * 1987-03-05 1992-07-01 Liposome Co Inc Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
JP2780755B2 (ja) * 1987-05-22 1998-07-30 ザ リポソーム カンパニー，インコーポレイテッド プロスタグランジン‐脂質製剤
DE68916439T2 (de) * 1988-10-05 1994-10-20 Vestar Inc Verfahren zur herstellung von liposomen mit verbesserter stabilität während des trocknens.
RU2014071C1 (ru) * 1991-03-26 1994-06-15 Научно-производственный центр медицинской биотехнологии Способ получения липосом, содержащих водорастворимые низкомолекулярные соединения
US5958881A (en) * 1991-04-25 1999-09-28 Korman; Louis Y. Composition containing VIP for injection and a method of enhancing visualization of tissues during medical procedures
WO1993020802A1 (en) * 1992-04-09 1993-10-28 Northwestern University Acoustically reflective liposomes and methods to make and use the same
DK0678017T3 (da) * 1993-11-05 1998-10-19 Amgen Inc Liposomfremstilling og materialeindkapslingsfremgangsmåde
JP3693209B2 (ja) * 1996-04-11 2005-09-07 三菱化学株式会社 閉鎖小胞の製造方法
RU2123328C1 (ru) * 1996-04-19 1998-12-20 Государственный научный центр вирусологии и биотехнологии "Вектор" Липосомальное противовирусное лекарственное средство для перорального применения
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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883665A (en) * 1985-04-11 1989-11-28 Takeda Chemical Industries, Ltd. Process for producing liposome composition
WO1997035561A1 (en) * 1996-03-28 1997-10-02 The Board Of Trustees Of The University Of Illinois Materials and methods for making improved liposome compositions
EP0800822A2 (en) * 1996-04-11 1997-10-15 Mitsubishi Chemical Corporation Method for preparing closed vesicles by rehydration of dehydrated vesicles

Also Published As

Publication number Publication date
RU2216315C2 (ru) 2003-11-20
NZ508960A (en) 2002-11-26
CN1312707A (zh) 2001-09-12
NO20006442D0 (no) 2000-12-15
GB2354166B (en) 2003-09-10
NO20006442L (no) 2001-02-15
ATE287258T1 (de) 2005-02-15
GB9813100D0 (en) 1998-08-19
KR20010053006A (ko) 2001-06-25
US9675554B1 (en) 2017-06-13
JP2003513003A (ja) 2003-04-08
EP1087754B1 (en) 2005-01-19
KR100658956B1 (ko) 2006-12-21
GB0030767D0 (en) 2001-01-31
EP1087754A1 (en) 2001-04-04
DE69923315D1 (de) 2005-02-24
ZA200007507B (en) 2002-03-14
GB2354166A (en) 2001-03-21
WO1999065465A1 (en) 1999-12-23
CA2335183A1 (en) 1999-12-23
DE69923315T2 (de) 2006-04-06
AU4518099A (en) 2000-01-05
JP4567882B2 (ja) 2010-10-20

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Legal Events

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired