CN1312707A - 形成脂质体的方法 - Google Patents

形成脂质体的方法 Download PDF

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Publication number
CN1312707A
CN1312707A CN99809563A CN99809563A CN1312707A CN 1312707 A CN1312707 A CN 1312707A CN 99809563 A CN99809563 A CN 99809563A CN 99809563 A CN99809563 A CN 99809563A CN 1312707 A CN1312707 A CN 1312707A
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CN
China
Prior art keywords
liposome
sucrose
sugar
size
lipoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN99809563A
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English (en)
Chinese (zh)
Inventor
G·格雷戈里尔迪斯
B·扎迪
P·N·贾亚赛克拉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UK Secretary of State for Defence
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UK Secretary of State for Defence
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Filing date
Publication date
Application filed by UK Secretary of State for Defence filed Critical UK Secretary of State for Defence
Publication of CN1312707A publication Critical patent/CN1312707A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN99809563A 1998-06-18 1999-06-16 形成脂质体的方法 Pending CN1312707A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9813100.6A GB9813100D0 (en) 1998-06-18 1998-06-18 Method of forming liposomes
GB9813100.6 1998-06-18

Publications (1)

Publication Number Publication Date
CN1312707A true CN1312707A (zh) 2001-09-12

Family

ID=10833946

Family Applications (1)

Application Number Title Priority Date Filing Date
CN99809563A Pending CN1312707A (zh) 1998-06-18 1999-06-16 形成脂质体的方法

Country Status (15)

Country Link
US (1) US9675554B1 (enExample)
EP (1) EP1087754B1 (enExample)
JP (1) JP4567882B2 (enExample)
KR (1) KR100658956B1 (enExample)
CN (1) CN1312707A (enExample)
AT (1) ATE287258T1 (enExample)
AU (1) AU749499B2 (enExample)
CA (1) CA2335183A1 (enExample)
DE (1) DE69923315T2 (enExample)
GB (2) GB9813100D0 (enExample)
NO (1) NO20006442L (enExample)
NZ (1) NZ508960A (enExample)
RU (1) RU2216315C2 (enExample)
WO (1) WO1999065465A1 (enExample)
ZA (1) ZA200007507B (enExample)

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CN107106421A (zh) * 2014-12-30 2017-08-29 赛特瑞恩股份有限公司 表皮生长因子和脂质体的混合型多层纳米结构及其制造方法

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ATE454884T1 (de) * 2004-10-18 2010-01-15 Polymun Scient Immunbio Forsch Liposomale zusammensetzung einen wirkstoff zur relaxierung glatter muskulatur enthaltend, die herstellung dieser zusammensetzung und deren therapeutische verwendung
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RU2300369C1 (ru) * 2005-12-27 2007-06-10 Наталья Ивановна Ларионова Способ получения полиэлектролитных микрочастиц, содержащих инкапсулируемое вещество, чувствительных к изменению состава окружающей среды
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CA2693651A1 (en) 2007-07-12 2009-01-15 Ronen Shemesh Bioactive peptides and method of using same
JP5362998B2 (ja) * 2008-01-10 2013-12-11 第一ファインケミカル株式会社 乾燥リポソーム製剤
US9445975B2 (en) 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
WO2010041255A2 (en) 2008-10-07 2010-04-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Liposomal systems comprising sphingomyelin
EP2184054A1 (en) 2008-11-08 2010-05-12 Lipoxen Technologies Limited Small Interfering RNA Delivery
WO2010140377A1 (ja) 2009-06-04 2010-12-09 独立行政法人産業技術総合研究所 マイコプラズマ感染症用ワクチン
RU2409668C1 (ru) * 2009-09-02 2011-01-20 Александр Анатольевич Ярославов Способ получения иммобилизованных бислойных везикул
KR20110068831A (ko) 2009-12-16 2011-06-22 재단법인 전라남도생물산업진흥재단 리포좀 조성물, 그 제조방법, 및 폐렴 백신으로서의 그 용도
FR2958851B1 (fr) * 2010-04-16 2012-06-29 Xeda International Nouvelles formulations d'ingredient(s) actif(s) d'origine vegetale ou leurs analogues synthetiques ou d'extrait(s) d'origine vegetale les contenant, et de lecithine
BR112013017267B1 (pt) 2011-01-04 2021-06-22 Archivel Farma, Sl Formulação de lipossomas, suspensão e composição farmacêutica
PT2768484T (pt) 2011-10-21 2019-10-28 Jazz Pharmaceuticals Res Llc Lipossomas liofilizados
IN2014MN01594A (enExample) 2012-01-12 2015-05-08 Archivel Farma Sl
EA023079B1 (ru) * 2012-12-24 2016-04-29 Общество С Ограниченной Ответственностью "Технология Лекарств" Способ получения липосомальной формы иринотекана (варианты)
JP6866060B2 (ja) * 2014-10-27 2021-04-28 花王株式会社 精製茶抽出物の製造方法
WO2016191700A1 (en) * 2015-05-27 2016-12-01 Nuvox Pharma Llc Treatment of acute complications of sickle cell disease
WO2017049132A1 (en) * 2015-09-18 2017-03-23 DNARx Systems and methods for nucleic acid expression in vivo
ES3036518T3 (en) 2015-10-16 2025-09-19 Ipsen Biopharm Ltd Stabilizing camptothecin pharmaceutical compositions
EP3600428A4 (en) 2017-03-23 2020-08-26 Dnarx SYSTEMS AND METHODS FOR THE EXPRESSION OF NUCLEIC ACIDS IN VIVO
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RU2697802C1 (ru) * 2018-08-23 2019-08-20 Федеральное Государственное Бюджетное Учреждение Науки Институт Биохимической Физики Им. Н.М. Эмануэля Российской Академии Наук (Ибхф Ран) Способ получения магнитных липосом

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107106421A (zh) * 2014-12-30 2017-08-29 赛特瑞恩股份有限公司 表皮生长因子和脂质体的混合型多层纳米结构及其制造方法
US11712407B2 (en) 2014-12-30 2023-08-01 Celltrion, Inc. Hybrid-type multi-lamellar nanostructure of epidermal growth factor and liposome and method for manufacturing same

Also Published As

Publication number Publication date
RU2216315C2 (ru) 2003-11-20
NZ508960A (en) 2002-11-26
NO20006442D0 (no) 2000-12-15
GB2354166B (en) 2003-09-10
NO20006442L (no) 2001-02-15
ATE287258T1 (de) 2005-02-15
GB9813100D0 (en) 1998-08-19
KR20010053006A (ko) 2001-06-25
US9675554B1 (en) 2017-06-13
JP2003513003A (ja) 2003-04-08
EP1087754B1 (en) 2005-01-19
KR100658956B1 (ko) 2006-12-21
AU749499B2 (en) 2002-06-27
GB0030767D0 (en) 2001-01-31
EP1087754A1 (en) 2001-04-04
DE69923315D1 (de) 2005-02-24
ZA200007507B (en) 2002-03-14
GB2354166A (en) 2001-03-21
WO1999065465A1 (en) 1999-12-23
CA2335183A1 (en) 1999-12-23
DE69923315T2 (de) 2006-04-06
AU4518099A (en) 2000-01-05
JP4567882B2 (ja) 2010-10-20

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