ATE272393T1 - Rekonstruktion gereinigter membranproteine in vorgefertigten liposomen - Google Patents
Rekonstruktion gereinigter membranproteine in vorgefertigten liposomenInfo
- Publication number
- ATE272393T1 ATE272393T1 AT00980600T AT00980600T ATE272393T1 AT E272393 T1 ATE272393 T1 AT E272393T1 AT 00980600 T AT00980600 T AT 00980600T AT 00980600 T AT00980600 T AT 00980600T AT E272393 T1 ATE272393 T1 AT E272393T1
- Authority
- AT
- Austria
- Prior art keywords
- liposomes
- solution
- providing
- mixture
- membrane proteins
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title abstract 7
- 108010052285 Membrane Proteins Proteins 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 abstract 4
- 102000002262 Thromboplastin Human genes 0.000 abstract 3
- 108010000499 Thromboplastin Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract 2
- 150000004670 unsaturated fatty acids Chemical class 0.000 abstract 2
- 102000018697 Membrane Proteins Human genes 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/829—Liposomes, e.g. encapsulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/459,137 US6248353B1 (en) | 1999-12-10 | 1999-12-10 | Reconstitution of purified membrane proteins into preformed liposomes |
| PCT/US2000/031927 WO2001041740A2 (en) | 1999-12-10 | 2000-11-20 | Reconstitution of purified membrane proteins into preformed liposomes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE272393T1 true ATE272393T1 (de) | 2004-08-15 |
Family
ID=23823557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00980600T ATE272393T1 (de) | 1999-12-10 | 2000-11-20 | Rekonstruktion gereinigter membranproteine in vorgefertigten liposomen |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6248353B1 (enExample) |
| EP (1) | EP1239833B1 (enExample) |
| JP (1) | JP4612261B2 (enExample) |
| AT (1) | ATE272393T1 (enExample) |
| DE (1) | DE60012785T2 (enExample) |
| ES (1) | ES2225271T3 (enExample) |
| WO (1) | WO2001041740A2 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020048596A1 (en) * | 1994-12-30 | 2002-04-25 | Gregor Cevc | Preparation for the transport of an active substance across barriers |
| PT1031346E (pt) | 1999-01-27 | 2002-09-30 | Idea Ag | Vacinacao nao invasiva atraves da pele |
| EP1031347B1 (en) | 1999-01-27 | 2002-04-17 | Idea Ag | Transnasal transport/immunisation with highly adaptable carriers |
| WO2001001962A1 (en) * | 1999-07-05 | 2001-01-11 | Idea Ag. | A method for the improvement of transport across adaptable semi-permeable barriers |
| US6248353B1 (en) * | 1999-12-10 | 2001-06-19 | Dade Behring Inc. | Reconstitution of purified membrane proteins into preformed liposomes |
| US7592008B2 (en) * | 2000-11-20 | 2009-09-22 | The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois | Membrane scaffold proteins |
| CA2429473C (en) * | 2000-11-20 | 2011-02-15 | The Board Of Trustees Of The University Of Illinois | Membrane scaffold proteins |
| US7622437B2 (en) * | 2000-11-20 | 2009-11-24 | The Board Of Trustees Of The University Of Illinois | Tissue factor compositions and methods |
| US7083958B2 (en) * | 2000-11-20 | 2006-08-01 | The Board Of Trustees Of The University Of Illinois | Membrane scaffold proteins |
| US6596543B2 (en) * | 2001-03-22 | 2003-07-22 | Dade Behring Inc. | Use of liposomes of defined composition and size for the preparation of prothrombin time reagents |
| US7015193B2 (en) * | 2001-04-20 | 2006-03-21 | University Of Vermont | Compositions and methods to control bleeding |
| CA2477982A1 (en) * | 2002-03-05 | 2003-09-18 | Transave, Inc. | Methods for entrapment of bioactive agent in a liposome or lipid complex |
| US7473432B2 (en) * | 2002-10-11 | 2009-01-06 | Idea Ag | NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery |
| US20050032113A1 (en) * | 2003-07-17 | 2005-02-10 | Mitsubishi Pharma Corporation | Membrane protein library for proteome analysis and method for preparing same |
| AU2005326758B2 (en) | 2004-06-23 | 2011-07-14 | Board Of Regents Of The University Of Texas System | Methods and compositions for the detection of biological molecules using a two particle complex |
| US7148067B2 (en) * | 2004-08-31 | 2006-12-12 | The Board Of Trustees Of The University Of Illinois | Thromboplastin reagents |
| KR20070086045A (ko) * | 2004-11-12 | 2007-08-27 | 이데아 아게 | 피부 상태 치료에서의 확대된 표면 집합체 |
| CN101151533A (zh) * | 2005-02-16 | 2008-03-26 | 伊利诺斯大学理事会 | 基于金属螯合脂质的促凝血剂 |
| AT501650A1 (de) * | 2005-02-22 | 2006-10-15 | Technoclone Ges M B H | Verfahren zur bestimmung der gerinnungsaktivierung sowie gerät zur durchführung des verfahrens |
| US7682808B2 (en) * | 2005-03-04 | 2010-03-23 | The Board Of Trustees Of The University Of Illinois | Coagulation and fibrinolytic cascades modulator |
| US20070117179A1 (en) * | 2005-09-27 | 2007-05-24 | Invitrogen Corporation | In vitro protein synthesis systems for membrane proteins that include adolipoproteins and phospholipid-adolipoprotein particles |
| JP2007106679A (ja) * | 2005-10-11 | 2007-04-26 | Shino Test Corp | 血液凝固反応促進剤 |
| EP1939218A1 (en) * | 2006-12-29 | 2008-07-02 | Thrombotargets Europe, S.L. | Microvesicles derived from recombinant yeast having haemostatic activities and uses thereof |
| WO2008106660A2 (en) * | 2007-03-01 | 2008-09-04 | Invitrogen Corporation | Isolated phospholipid-protein particles |
| WO2008109712A2 (en) | 2007-03-05 | 2008-09-12 | Washington University | Nanoparticle delivery systems for membrane-integrating peptides |
| EP2197497B1 (en) | 2007-09-27 | 2016-06-01 | ImmunoVaccine Technologies Inc. | Use of liposomes in a carrier comprising a continuous hydrophobic phase for delivery of polynucleotides in vivo |
| EP2062661A1 (en) * | 2007-09-28 | 2009-05-27 | Proviron Holding | Organic de-icer removal |
| US20100209452A1 (en) * | 2007-10-03 | 2010-08-19 | Immunovaccine Technologies, Inc | Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof |
| US8821861B2 (en) * | 2007-10-05 | 2014-09-02 | The Board Of Trustees Of The University Of Illinois | Fibrin sealant |
| US20100297257A1 (en) * | 2007-11-09 | 2010-11-25 | National Institutes Of Health (Nih), U.S. Dept. Of Health And Human Services (Dhhs) | Anticoagulant antagonist and hemophillia procoagulant |
| US20090220588A1 (en) * | 2008-02-21 | 2009-09-03 | Massachusetts Institute Of Technology | Simultaneous Delivery of Receptors and/or Co-Receptors for Growth Factor Stability and Activity |
| JP5715051B2 (ja) | 2008-06-05 | 2015-05-07 | イムノバクシーン・テクノロジーズ・インコーポレイテッドImmunovaccine Technologies Inc. | リポソーム、抗原、ポリヌクレオチド及び疎水性物質の連続相を含む担体を含む組成物 |
| US8956600B2 (en) | 2009-08-10 | 2015-02-17 | Taiwan Liposome Co. Ltd. | Ophthalmic drug delivery system containing phospholipid and cholesterol |
| US12419839B2 (en) | 2009-10-09 | 2025-09-23 | Signablok, Inc. | Methods and compositions for targeted delivery of protein fragments |
| US10525152B2 (en) | 2009-10-09 | 2020-01-07 | Signablok, Inc. | Methods and compositions for targeted imaging |
| US10894098B2 (en) | 2012-04-09 | 2021-01-19 | Signablok, Inc. | Methods and compositions for targeted imaging |
| KR101458315B1 (ko) | 2013-07-19 | 2014-11-04 | 전북대학교산학협력단 | 표면 개질된 리포좀 및 그 제조방법 |
| JP6652873B2 (ja) * | 2016-03-30 | 2020-02-26 | シスメックス株式会社 | プロトロンビン時間測定用試薬、その製造方法およびプロトロンビン時間の測定方法 |
| JP6626761B2 (ja) * | 2016-03-30 | 2019-12-25 | シスメックス株式会社 | プロトロンビン時間測定用試薬およびその製造方法 |
| US12246057B2 (en) | 2018-04-13 | 2025-03-11 | Board Of Regents, The University Of Texas System | Transmembrane stem cell factor (tm-SCF) lipid nanocarriers and methods of use thereof |
| JP7376478B2 (ja) * | 2018-07-06 | 2023-11-08 | 株式会社Lsiメディエンス | リポソームを含有する液状血液凝固能測定試薬 |
| JP7153519B2 (ja) * | 2018-09-28 | 2022-10-14 | シスメックス株式会社 | 凝固時間測定用試薬及びその製造方法、試薬キット及び凝固時間の測定方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL238873A (enExample) | 1958-05-16 | |||
| JPS56129859A (en) * | 1980-03-14 | 1981-10-12 | Sekisui Chem Co Ltd | Plastic container for blood inspection |
| US4873089A (en) * | 1985-07-12 | 1989-10-10 | Cornell Research Foundation Inc., Cornell University | Proteoliposomes as drug carriers |
| IL79114A (en) * | 1985-08-07 | 1990-09-17 | Allergan Pharma | Method and composition for making liposomes |
| JPH0650999B2 (ja) | 1988-09-12 | 1994-07-06 | 日本商事株式会社 | 血液凝固因子安定化法 |
| US5472850A (en) | 1991-04-10 | 1995-12-05 | Oklahoma Medical Research Foundation | Quantitative clotting assay for activated factor VII |
| DE59109269D1 (de) | 1990-06-28 | 2005-12-15 | Hoechst Ag | Fusionsproteine mit Immunglobulinanteilen, ihre Herstellung und Verwendung |
| US5314695A (en) | 1990-11-13 | 1994-05-24 | Corvas International, Inc. | Tissue factor based prothrombin time reagent |
| US5248590A (en) | 1991-07-22 | 1993-09-28 | Becton, Dickinson And Company | Surface modified liposomes |
| DE69224622T2 (de) * | 1991-10-04 | 1998-11-05 | Dade Behring, Inc., Deerfield, Ill. | Herstellung von prothrombinzeit-reagenzien aus rekombinantem menschlichem gewebefaktor und sythetischen phospholipiden |
| AU674139B2 (en) | 1992-04-13 | 1996-12-12 | Ortho Diagnostic Systems Inc. | Synthetic phospholipid reagent |
| US5358853A (en) | 1992-08-03 | 1994-10-25 | Akzo Av | Liquid thromboplastin reagent |
| DE4243729A1 (de) | 1992-12-23 | 1994-06-30 | Behringwerke Ag | Verfahren zur Reaktivierung von gereinigten Membranproteinen |
| JP3591837B2 (ja) | 1994-02-17 | 2004-11-24 | ニューヨーク・ブラッド・センター・インコーポレイテッド | フィブリン膠およびリポソームを含有する生物学的生体接着剤組成物、その製造方法および使用 |
| DE4416166C2 (de) | 1994-05-06 | 1997-11-20 | Immuno Ag | Stabiles Präparat zur Behandlung von Blutgerinnungsstörungen |
| US6100072A (en) * | 1997-04-23 | 2000-08-08 | Instrumentation Laboratory S.P.A. | Recombinant rabbit tissue factor based prothrombin time reagent |
| JP4039722B2 (ja) * | 1997-12-01 | 2008-01-30 | シスメックス株式会社 | 複合因子測定試薬 |
| US6248353B1 (en) * | 1999-12-10 | 2001-06-19 | Dade Behring Inc. | Reconstitution of purified membrane proteins into preformed liposomes |
-
1999
- 1999-12-10 US US09/459,137 patent/US6248353B1/en not_active Expired - Lifetime
-
2000
- 2000-11-20 AT AT00980600T patent/ATE272393T1/de active
- 2000-11-20 WO PCT/US2000/031927 patent/WO2001041740A2/en not_active Ceased
- 2000-11-20 DE DE60012785T patent/DE60012785T2/de not_active Expired - Lifetime
- 2000-11-20 EP EP00980600A patent/EP1239833B1/en not_active Expired - Lifetime
- 2000-11-20 ES ES00980600T patent/ES2225271T3/es not_active Expired - Lifetime
- 2000-11-20 JP JP2001542908A patent/JP4612261B2/ja not_active Expired - Fee Related
-
2001
- 2001-03-22 US US09/815,195 patent/US6706861B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20020012699A1 (en) | 2002-01-31 |
| US6248353B1 (en) | 2001-06-19 |
| ES2225271T3 (es) | 2005-03-16 |
| DE60012785D1 (de) | 2004-09-09 |
| JP2003516525A (ja) | 2003-05-13 |
| EP1239833A2 (en) | 2002-09-18 |
| WO2001041740A3 (en) | 2002-01-17 |
| WO2001041740A2 (en) | 2001-06-14 |
| DE60012785T2 (de) | 2005-08-11 |
| JP4612261B2 (ja) | 2011-01-12 |
| US6706861B2 (en) | 2004-03-16 |
| EP1239833B1 (en) | 2004-08-04 |
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| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification |
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