ATE268187T1 - Bioaktivierte diagnostische bilderzeugungskontrastmittel - Google Patents

Bioaktivierte diagnostische bilderzeugungskontrastmittel

Info

Publication number
ATE268187T1
ATE268187T1 AT97916974T AT97916974T ATE268187T1 AT E268187 T1 ATE268187 T1 AT E268187T1 AT 97916974 T AT97916974 T AT 97916974T AT 97916974 T AT97916974 T AT 97916974T AT E268187 T1 ATE268187 T1 AT E268187T1
Authority
AT
Austria
Prior art keywords
agents
bioactivated
contrast agents
diagnostic imaging
imaging contrast
Prior art date
Application number
AT97916974T
Other languages
German (de)
English (en)
Inventor
Randall B Lauffer
Thomas J Mcmurry
Stephen O Dunham
Daniel M Scott
David J Parmelee
Stephane Dumas
Original Assignee
Epix Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epix Medical Inc filed Critical Epix Medical Inc
Application granted granted Critical
Publication of ATE268187T1 publication Critical patent/ATE268187T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97916974T 1996-04-01 1997-03-25 Bioaktivierte diagnostische bilderzeugungskontrastmittel ATE268187T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1444896P 1996-04-01 1996-04-01
PCT/US1997/004804 WO1997036619A2 (en) 1996-04-01 1997-03-25 Bioactivated diagnostic imaging contrast agents

Publications (1)

Publication Number Publication Date
ATE268187T1 true ATE268187T1 (de) 2004-06-15

Family

ID=21765541

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97916974T ATE268187T1 (de) 1996-04-01 1997-03-25 Bioaktivierte diagnostische bilderzeugungskontrastmittel

Country Status (18)

Country Link
US (3) US6709646B2 (enExample)
EP (1) EP0907379B1 (enExample)
JP (2) JP2000507577A (enExample)
KR (1) KR20060025233A (enExample)
CN (1) CN1108824C (enExample)
AT (1) ATE268187T1 (enExample)
AU (1) AU726914B2 (enExample)
BR (1) BR9708470A (enExample)
CA (1) CA2247620A1 (enExample)
DE (1) DE69729380T2 (enExample)
DK (1) DK0907379T3 (enExample)
ES (1) ES2217408T3 (enExample)
IL (1) IL125895A (enExample)
IS (1) IS2059B (enExample)
NO (1) NO319674B1 (enExample)
NZ (1) NZ331629A (enExample)
PT (1) PT907379E (enExample)
WO (1) WO1997036619A2 (enExample)

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Also Published As

Publication number Publication date
CN1108824C (zh) 2003-05-21
HK1016877A1 (en) 1999-11-12
IL125895A0 (en) 1999-04-11
IL125895A (en) 2001-09-13
CA2247620A1 (en) 1997-10-09
US7147837B2 (en) 2006-12-12
US20020034476A1 (en) 2002-03-21
KR20060025233A (ko) 2006-03-20
NO319674B1 (no) 2005-09-05
US20060275216A1 (en) 2006-12-07
IS2059B (is) 2005-10-14
NO984543L (no) 1998-11-26
WO1997036619A2 (en) 1997-10-09
ES2217408T3 (es) 2004-11-01
IS4833A (is) 1998-08-26
NZ331629A (en) 2000-04-28
US20040156785A1 (en) 2004-08-12
CN1215341A (zh) 1999-04-28
JP2000507577A (ja) 2000-06-20
DE69729380D1 (de) 2004-07-08
US6709646B2 (en) 2004-03-23
EP0907379A2 (en) 1999-04-14
AU726914B2 (en) 2000-11-23
PT907379E (pt) 2004-09-30
DE69729380T2 (de) 2005-07-14
JP2004210796A (ja) 2004-07-29
BR9708470A (pt) 1999-04-13
AU2544897A (en) 1997-10-22
EP0907379B1 (en) 2004-06-02
NO984543D0 (no) 1998-09-29
DK0907379T3 (da) 2004-08-16
WO1997036619A3 (en) 1998-01-29

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