NO984543L - Bioaktiverte diagnostiske imaging kontrastmidler - Google Patents
Bioaktiverte diagnostiske imaging kontrastmidlerInfo
- Publication number
- NO984543L NO984543L NO984543A NO984543A NO984543L NO 984543 L NO984543 L NO 984543L NO 984543 A NO984543 A NO 984543A NO 984543 A NO984543 A NO 984543A NO 984543 L NO984543 L NO 984543L
- Authority
- NO
- Norway
- Prior art keywords
- agents
- bioactivated
- contrast agents
- diagnostic imaging
- imaging contrast
- Prior art date
Links
- 239000002872 contrast media Substances 0.000 title abstract 2
- 238000002059 diagnostic imaging Methods 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- 238000002595 magnetic resonance imaging Methods 0.000 abstract 2
- 238000012634 optical imaging Methods 0.000 abstract 2
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000012216 imaging agent Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 238000011896 sensitive detection Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1444896P | 1996-04-01 | 1996-04-01 | |
PCT/US1997/004804 WO1997036619A2 (en) | 1996-04-01 | 1997-03-25 | Bioactivated diagnostic imaging contrast agents |
Publications (3)
Publication Number | Publication Date |
---|---|
NO984543D0 NO984543D0 (no) | 1998-09-29 |
NO984543L true NO984543L (no) | 1998-11-26 |
NO319674B1 NO319674B1 (no) | 2005-09-05 |
Family
ID=21765541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19984543A NO319674B1 (no) | 1996-04-01 | 1998-09-29 | Bioaktiverte diagnostiske imaging kontrastmidler |
Country Status (19)
Country | Link |
---|---|
US (3) | US6709646B2 (no) |
EP (1) | EP0907379B1 (no) |
JP (2) | JP2000507577A (no) |
KR (1) | KR20060025233A (no) |
CN (1) | CN1108824C (no) |
AT (1) | ATE268187T1 (no) |
AU (1) | AU726914B2 (no) |
BR (1) | BR9708470A (no) |
CA (1) | CA2247620A1 (no) |
DE (1) | DE69729380T2 (no) |
DK (1) | DK0907379T3 (no) |
ES (1) | ES2217408T3 (no) |
HK (1) | HK1016877A1 (no) |
IL (1) | IL125895A (no) |
IS (1) | IS2059B (no) |
NO (1) | NO319674B1 (no) |
NZ (1) | NZ331629A (no) |
PT (1) | PT907379E (no) |
WO (1) | WO1997036619A2 (no) |
Families Citing this family (86)
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US6770261B2 (en) * | 1995-06-02 | 2004-08-03 | Research Corporation Technologies | Magnetic resonance imaging agents for the detection of physiological agents |
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US5900228A (en) | 1996-07-31 | 1999-05-04 | California Institute Of Technology | Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye |
US6675035B1 (en) * | 1997-06-20 | 2004-01-06 | Imaging Diagnostic Systems, Inc. | Phantom for optical and magnetic resonance imaging quality control |
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US6713046B1 (en) | 1997-10-27 | 2004-03-30 | Research Corporation Technologies | Magnetic resonance imaging agents for the delivery of therapeutic agents |
WO1999021592A1 (en) * | 1997-10-27 | 1999-05-06 | California Institute Of Technology | Magnetic resonance imaging agents for the delivery of therapeutic agents |
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IT1297034B1 (it) * | 1997-12-30 | 1999-08-03 | Bracco Spa | Acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico |
IT1297035B1 (it) * | 1997-12-30 | 1999-08-03 | Bracco Spa | Derivati dell'acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico |
US6167297A (en) | 1999-05-05 | 2000-12-26 | Benaron; David A. | Detecting, localizing, and targeting internal sites in vivo using optical contrast agents |
US6230586B1 (en) * | 1999-05-21 | 2001-05-15 | Chung-Hsi Chang | Electric drive device for a bicycle |
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US20040146463A1 (en) * | 2000-05-04 | 2004-07-29 | Meade Thomas J. | Functional MRI agents for cancer imaging |
EP1283728A2 (en) * | 2000-05-23 | 2003-02-19 | Amersham Health AS | Contrast agents |
US6748259B1 (en) | 2000-06-15 | 2004-06-08 | Spectros Corporation | Optical imaging of induced signals in vivo under ambient light conditions |
WO2002006287A2 (en) | 2000-07-17 | 2002-01-24 | California Institute Of Technology | Macrocyclic mri contrast agents |
WO2002028441A2 (en) | 2000-10-04 | 2002-04-11 | California Institute Of Technology | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits |
US20030004236A1 (en) * | 2001-04-20 | 2003-01-02 | Meade Thomas J. | Magnetic resonance imaging agents for detection and delivery of therapeutic agents and detection of physiological substances |
US20020197648A1 (en) * | 2001-05-02 | 2002-12-26 | Silva Robin M. | High throughput screening methods using magnetic resonance imaging agents |
TWI221406B (en) | 2001-07-30 | 2004-10-01 | Epix Medical Inc | Systems and methods for targeted magnetic resonance imaging of the vascular system |
ES2398393T3 (es) | 2002-03-01 | 2013-03-15 | Dyax Corp. | Péptidos de unión a KDR y a VEGF/KDR y su uso en diagnóstico y terapia |
US7794693B2 (en) | 2002-03-01 | 2010-09-14 | Bracco International B.V. | Targeting vector-phospholipid conjugates |
US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US20050100963A1 (en) | 2002-03-01 | 2005-05-12 | Dyax Corporation | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US20030198597A1 (en) * | 2002-04-22 | 2003-10-23 | Meade Thomas J. | Novel macrocyclic activatible magnetic resonance imaging contrast agents |
DE60322076D1 (de) * | 2002-07-22 | 2008-08-21 | Bracco Imaging Spa | Zellmarkierungsverfahren mit paramagnetischen komplexen für mrt-anwendungen |
US20050163821A1 (en) * | 2002-08-02 | 2005-07-28 | Hsing-Wen Sung | Drug-eluting Biodegradable Stent and Delivery Means |
US7226577B2 (en) | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
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US20050112065A1 (en) * | 2003-07-09 | 2005-05-26 | Drummond Daryl C. | Remote detection of substance delivery to cells |
US20050106100A1 (en) * | 2003-09-03 | 2005-05-19 | Harris Thomas D. | Compounds containing matrix metalloproteinase substrates and methods of their use |
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EP1863546B1 (en) * | 2005-03-11 | 2015-10-07 | Wake Forest University Health Sciences | Production of tissue engineered heart valves |
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US20060204445A1 (en) * | 2005-03-11 | 2006-09-14 | Anthony Atala | Cell scaffold matrices with image contrast agents |
US7531503B2 (en) * | 2005-03-11 | 2009-05-12 | Wake Forest University Health Sciences | Cell scaffold matrices with incorporated therapeutic agents |
US8728463B2 (en) * | 2005-03-11 | 2014-05-20 | Wake Forest University Health Science | Production of tissue engineered digits and limbs |
US20060204539A1 (en) * | 2005-03-11 | 2006-09-14 | Anthony Atala | Electrospun cell matrices |
EP1743658A1 (en) | 2005-07-14 | 2007-01-17 | Schering Aktiengesellschaft | Optical imaging of rheumatoid arthritis |
CN101252954A (zh) * | 2005-06-30 | 2008-08-27 | 布里斯托尔-迈尔斯斯奎布药品公司 | 作为显像剂的酰肼偶联物 |
JP5377965B2 (ja) * | 2005-09-09 | 2013-12-25 | ジョージア ステート ユニバーシティ リサーチ ファウンデーション、インコーポレイテッド | 標的化された造影剤および造影剤を標的化するための方法 |
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US9951324B2 (en) | 2010-02-25 | 2018-04-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
CN102188722A (zh) * | 2010-03-18 | 2011-09-21 | 中国科学院福建物质结构研究所 | 一种含二价铁的磁共振成像造影剂 |
US8192429B2 (en) | 2010-06-29 | 2012-06-05 | Theravant, Inc. | Abnormality eradication through resonance |
WO2013131994A2 (en) * | 2012-03-08 | 2013-09-12 | Thommen Medical Ag | Coating for the diagnosis of inflammatory tissues in dental applications |
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US10092679B2 (en) | 2013-10-18 | 2018-10-09 | Wake Forest University Health Sciences | Laminous vascular constructs combining cell sheet engineering and electrospinning technologies |
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WO2016149404A1 (en) | 2015-03-16 | 2016-09-22 | California Institute Of Technology | Botulinum neurotoxin-specific capture agents, compositions, and methods of using and making |
CN108290927B (zh) | 2015-07-15 | 2022-06-24 | 加州理工学院 | Il-17f-特异性捕获剂、组合物以及使用和制造的方法 |
US20170319722A1 (en) | 2016-04-04 | 2017-11-09 | Indi Molecular, Inc. | Cd8-specific capture agents, compositions, and methods of using and making |
WO2018064597A1 (en) | 2016-09-29 | 2018-04-05 | Indi Molecular, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same |
WO2018085375A1 (en) | 2016-11-01 | 2018-05-11 | Ohio State Innovation Foundation | Methods for the iodination of biomolecules |
CA3057976A1 (en) * | 2017-04-27 | 2018-11-01 | The Regents Of The University Of California | Modified mri contrast agents and uses thereof |
EP3638687A1 (en) | 2017-06-15 | 2020-04-22 | Indi Molecular, Inc. | Il-17f and il-17a-specific capture agents, compositions, and methods of using and making |
WO2019075213A1 (en) * | 2017-10-11 | 2019-04-18 | Northwestern University | HEPARIN CONJUGATED TO PEPTIDES BINDING TO COLLAGEN FOR TARGETING BIOLOGICAL AND SYNTHETIC FABRICS |
CN108314695B (zh) * | 2018-01-04 | 2020-06-16 | 南京邮电大学 | 一种异种双核金属配合物的制备及应用 |
US11919972B2 (en) | 2018-11-02 | 2024-03-05 | Regeneron Pharmaceuticals, Inc. | Peptide libraries with non-canonical amino acids |
WO2020097531A1 (en) | 2018-11-08 | 2020-05-14 | Indi Molecular, Inc. | Theranostic capture agents, compositions, and methods of using and making |
WO2020186091A1 (en) | 2019-03-12 | 2020-09-17 | Indi Molecular, Inc. | Cross-linked epitopes and methods of use thereof |
US20200371101A1 (en) | 2019-05-20 | 2020-11-26 | Indi Molecular, Inc. | Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1) |
US11414460B2 (en) | 2019-07-19 | 2022-08-16 | Institute For Systems Biology | KRAS-specific capture agents, compositions, and methods of making and using |
CN112891566A (zh) * | 2019-12-04 | 2021-06-04 | 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 | 一种纳米材料及其制备方法和包含其的造影剂 |
EP4143227A2 (en) | 2020-04-30 | 2023-03-08 | Sairopa B.V. | Anti-cd103 antibodies |
WO2022098743A1 (en) | 2020-11-03 | 2022-05-12 | Indi Molecular, Inc. | Compositions, imaging, and therapeutic methods targeting folate receptor 1 (folr1) |
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Family Cites Families (15)
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US4880008A (en) | 1985-05-08 | 1989-11-14 | The General Hospital Corporation | Vivo enhancement of NMR relaxivity |
US4899755A (en) | 1985-05-08 | 1990-02-13 | The General Hospital Corporation | Hepatobiliary NMR contrast agents |
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US5171563A (en) | 1988-09-30 | 1992-12-15 | Neorx Corporation | Cleavable linkers for the reduction of non-target organ retention of immunoconjugates |
US5094848A (en) * | 1989-06-30 | 1992-03-10 | Neorx Corporation | Cleavable diphosphate and amidated diphosphate linkers |
WO1991003200A1 (en) * | 1989-08-28 | 1991-03-21 | The General Hospital Corporation | Hydroxy-aryl metal chelates for diagnostic nmr imaging |
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EP0731797B1 (en) * | 1993-12-03 | 1999-09-08 | BRACCO S.p.A. | Paramagnetic chelates for nuclear magnetic resonance diagnosis |
DE4341724A1 (de) * | 1993-12-03 | 1995-06-08 | Schering Ag | Halogenaryl-substituierte Metallkomplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik, sowie Verfahren zur Herstellung der Komplexe und Mittel |
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-
1997
- 1997-03-25 NZ NZ331629A patent/NZ331629A/xx unknown
- 1997-03-25 AU AU25448/97A patent/AU726914B2/en not_active Ceased
- 1997-03-25 DE DE69729380T patent/DE69729380T2/de not_active Expired - Fee Related
- 1997-03-25 EP EP97916974A patent/EP0907379B1/en not_active Expired - Lifetime
- 1997-03-25 CA CA002247620A patent/CA2247620A1/en not_active Abandoned
- 1997-03-25 KR KR1020067003261A patent/KR20060025233A/ko not_active Application Discontinuation
- 1997-03-25 ES ES97916974T patent/ES2217408T3/es not_active Expired - Lifetime
- 1997-03-25 BR BR9708470A patent/BR9708470A/pt not_active Application Discontinuation
- 1997-03-25 AT AT97916974T patent/ATE268187T1/de not_active IP Right Cessation
- 1997-03-25 DK DK97916974T patent/DK0907379T3/da active
- 1997-03-25 CN CN97193542A patent/CN1108824C/zh not_active Expired - Fee Related
- 1997-03-25 PT PT97916974T patent/PT907379E/pt unknown
- 1997-03-25 IL IL12589597A patent/IL125895A/en not_active IP Right Cessation
- 1997-03-25 WO PCT/US1997/004804 patent/WO1997036619A2/en not_active Application Discontinuation
- 1997-03-25 JP JP9535373A patent/JP2000507577A/ja not_active Ceased
-
1998
- 1998-08-26 IS IS4833A patent/IS2059B/is unknown
- 1998-09-29 NO NO19984543A patent/NO319674B1/no unknown
-
1999
- 1999-04-27 HK HK99101864A patent/HK1016877A1/xx not_active IP Right Cessation
-
2001
- 2001-09-14 US US09/952,971 patent/US6709646B2/en not_active Expired - Fee Related
-
2004
- 2004-01-16 US US10/758,729 patent/US7147837B2/en not_active Expired - Fee Related
- 2004-02-27 JP JP2004055545A patent/JP2004210796A/ja active Pending
-
2006
- 2006-08-16 US US11/504,851 patent/US20060275216A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
NO984543D0 (no) | 1998-09-29 |
DE69729380D1 (de) | 2004-07-08 |
CA2247620A1 (en) | 1997-10-09 |
US20020034476A1 (en) | 2002-03-21 |
IL125895A (en) | 2001-09-13 |
US7147837B2 (en) | 2006-12-12 |
WO1997036619A3 (en) | 1998-01-29 |
DK0907379T3 (da) | 2004-08-16 |
KR20060025233A (ko) | 2006-03-20 |
US20040156785A1 (en) | 2004-08-12 |
NZ331629A (en) | 2000-04-28 |
JP2000507577A (ja) | 2000-06-20 |
PT907379E (pt) | 2004-09-30 |
ATE268187T1 (de) | 2004-06-15 |
ES2217408T3 (es) | 2004-11-01 |
CN1215341A (zh) | 1999-04-28 |
BR9708470A (pt) | 1999-04-13 |
IS2059B (is) | 2005-10-14 |
IS4833A (is) | 1998-08-26 |
US6709646B2 (en) | 2004-03-23 |
CN1108824C (zh) | 2003-05-21 |
US20060275216A1 (en) | 2006-12-07 |
NO319674B1 (no) | 2005-09-05 |
AU2544897A (en) | 1997-10-22 |
HK1016877A1 (en) | 1999-11-12 |
EP0907379A2 (en) | 1999-04-14 |
DE69729380T2 (de) | 2005-07-14 |
EP0907379B1 (en) | 2004-06-02 |
JP2004210796A (ja) | 2004-07-29 |
WO1997036619A2 (en) | 1997-10-09 |
IL125895A0 (en) | 1999-04-11 |
AU726914B2 (en) | 2000-11-23 |
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