ES2189873T3 - Agentes de imagen de resonancia magnetica para la deteccion de agentes fisiologicos. - Google Patents

Agentes de imagen de resonancia magnetica para la deteccion de agentes fisiologicos.

Info

Publication number
ES2189873T3
ES2189873T3 ES96917061T ES96917061T ES2189873T3 ES 2189873 T3 ES2189873 T3 ES 2189873T3 ES 96917061 T ES96917061 T ES 96917061T ES 96917061 T ES96917061 T ES 96917061T ES 2189873 T3 ES2189873 T3 ES 2189873T3
Authority
ES
Spain
Prior art keywords
agents
magnetic resonance
resonance image
detection
physiological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96917061T
Other languages
English (en)
Inventor
Thomas Meade
Scott Fraser
Russell Jacobs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Corp Technologies Inc
Original Assignee
Research Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp Technologies Inc filed Critical Research Corp Technologies Inc
Application granted granted Critical
Publication of ES2189873T3 publication Critical patent/ES2189873T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

LA INVENCION SE REFIERE A NUEVOS AGENTES DE CONTRASTE DE IMAGEN DE RESONANCIA MAGNETICA Y A METODOS PARA DETECTAR SEÑALES O SUSTANCIAS FISIOLOGICAS.
ES96917061T 1995-06-02 1996-06-03 Agentes de imagen de resonancia magnetica para la deteccion de agentes fisiologicos. Expired - Lifetime ES2189873T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46051195A 1995-06-02 1995-06-02
US08/486,968 US5707605A (en) 1995-06-02 1995-06-07 Magnetic resonance imaging agents for the detection of physiological agents

Publications (1)

Publication Number Publication Date
ES2189873T3 true ES2189873T3 (es) 2003-07-16

Family

ID=27039723

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96917061T Expired - Lifetime ES2189873T3 (es) 1995-06-02 1996-06-03 Agentes de imagen de resonancia magnetica para la deteccion de agentes fisiologicos.

Country Status (10)

Country Link
US (1) US5707605A (es)
EP (1) EP0831928B1 (es)
JP (1) JPH11506455A (es)
AT (1) ATE230278T1 (es)
AU (1) AU712899B2 (es)
CA (1) CA2222974C (es)
DE (1) DE69625595T2 (es)
ES (1) ES2189873T3 (es)
NO (1) NO975517L (es)
WO (1) WO1996038184A2 (es)

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AU2001259575A1 (en) * 2000-05-04 2001-11-12 Research Corporation Technologies Magnetic resonance imaging agents for the delivery of therapeutic agents
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US20030165431A1 (en) * 2000-07-13 2003-09-04 The Regents Of The University Of California Method for detecting macromolecular conformational change and binding information
US6656450B2 (en) 2000-07-17 2003-12-02 California Institute Of Technology, Inc. Macrocyclic magnetic resonance imaging contrast agents
WO2002028441A2 (en) 2000-10-04 2002-04-11 California Institute Of Technology Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits
JP2004530408A (ja) * 2000-10-19 2004-10-07 ザ ジェネラル ホスピタル コーポレーション 酵素活性の画像化法
US20030004236A1 (en) * 2001-04-20 2003-01-02 Meade Thomas J. Magnetic resonance imaging agents for detection and delivery of therapeutic agents and detection of physiological substances
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US20050255038A1 (en) * 2002-04-12 2005-11-17 A And D Bioscience, Inc. Conjugates comprising cancer cell specific ligands, a sugar and diagnostic agents and uses thereof
WO2003094842A2 (en) * 2002-05-07 2003-11-20 A & D Bioscience, Inc. Conjugates comprising central nervous system active drug
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US20050215487A1 (en) * 2002-06-27 2005-09-29 Holick Michael F Conjugates comprising an nsaid and a sugar and uses thereof
JP3606280B2 (ja) * 2002-07-16 2005-01-05 日産自動車株式会社 樹脂製チューブ及び燃料系配管用チューブ
US20040022735A1 (en) * 2002-08-02 2004-02-05 Uzgiris Egidijus E Enzyme activated contrast agents
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US20050036947A1 (en) * 2003-08-12 2005-02-17 General Electric Company Target-specific activatable polymeric imaging agents
US20050232866A1 (en) * 2004-03-26 2005-10-20 Alerion Biomedical Inc. Biochemically-activated contrast agents for magnetic resonance imaging
FR2868320B1 (fr) * 2004-03-31 2007-11-02 Centre Nat Rech Scient Cnrse Agent de contraste pour l'imagerie par resonance magnetique
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US20060088475A1 (en) * 2004-05-10 2006-04-27 Northwestern University Self-immolative magnetic resonance imaging contrast agents sensitive to beta-glucuronidase
JP2008513533A (ja) * 2004-09-23 2008-05-01 ゲルベ Ｃｅｓｔイメージング用の造影剤封入システム
EP1940841B9 (fr) * 2005-10-07 2017-04-19 Guerbet Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
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RU2396983C1 (ru) * 2009-04-13 2010-08-20 Виктор Сергеевич Скуридин Контрастная композиция для медицинской диагностики на основе комплексов гадолиния
US8518405B2 (en) 2009-10-08 2013-08-27 The University Of North Carolina At Charlotte Tumor specific antibodies and uses therefor
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DK2721045T3 (en) * 2011-06-20 2017-07-24 Radiomedix Inc COMPOSITIONS, METHODS OF SYNTHESIS AND USE OF CARBOHYDRATE TARGETED AGENTS
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RU2755181C2 (ru) 2016-11-28 2021-09-14 Байер Фарма Акциенгезельшафт Новые хелатные соединения гадолиния с высокой релаксивностью для применения в магнитно-резонансной визуализации
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CN113164628A (zh) 2018-11-23 2021-07-23 拜耳股份有限公司 造影介质制剂及其制备方法

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Also Published As

Publication number Publication date
NO975517D0 (no) 1997-12-01
EP0831928B1 (en) 2003-01-02
DE69625595T2 (de) 2003-11-27
WO1996038184A2 (en) 1996-12-05
WO1996038184A3 (en) 1997-03-13
JPH11506455A (ja) 1999-06-08
US5707605A (en) 1998-01-13
CA2222974A1 (en) 1996-12-05
CA2222974C (en) 2004-05-11
AU5975196A (en) 1996-12-18
NO975517L (no) 1998-01-19
EP0831928A2 (en) 1998-04-01
ATE230278T1 (de) 2003-01-15
AU712899B2 (en) 1999-11-18
DE69625595D1 (de) 2003-02-06

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