ATE249845T1 - Strahlenschutzsubstanz fur radioisotopen markierte peptiden - Google Patents

Strahlenschutzsubstanz fur radioisotopen markierte peptiden

Info

Publication number
ATE249845T1
ATE249845T1 AT98928875T AT98928875T ATE249845T1 AT E249845 T1 ATE249845 T1 AT E249845T1 AT 98928875 T AT98928875 T AT 98928875T AT 98928875 T AT98928875 T AT 98928875T AT E249845 T1 ATE249845 T1 AT E249845T1
Authority
AT
Austria
Prior art keywords
radiation protection
labeled peptides
radioisotope labeled
protection substance
radiolabeled
Prior art date
Application number
AT98928875T
Other languages
German (de)
English (en)
Inventor
Dan Shochat
Albert S K Chan
Michael J Buckley
David Colcher
Original Assignee
Coulter Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter Pharm Inc filed Critical Coulter Pharm Inc
Application granted granted Critical
Publication of ATE249845T1 publication Critical patent/ATE249845T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT98928875T 1997-06-03 1998-06-03 Strahlenschutzsubstanz fur radioisotopen markierte peptiden ATE249845T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4838797P 1997-06-03 1997-06-03
US08/918,525 US5961955A (en) 1997-06-03 1997-08-21 Radioprotectant for peptides labeled with radioisotope
PCT/US1998/011428 WO1998055154A1 (en) 1997-06-03 1998-06-03 Radioprotectant for peptides labeled with radioisotope

Publications (1)

Publication Number Publication Date
ATE249845T1 true ATE249845T1 (de) 2003-10-15

Family

ID=26726075

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98928875T ATE249845T1 (de) 1997-06-03 1998-06-03 Strahlenschutzsubstanz fur radioisotopen markierte peptiden

Country Status (14)

Country Link
US (2) US5961955A (OSRAM)
EP (1) EP1003560B1 (OSRAM)
JP (1) JP4291417B2 (OSRAM)
AT (1) ATE249845T1 (OSRAM)
AU (1) AU743823B2 (OSRAM)
CA (1) CA2290987A1 (OSRAM)
DE (1) DE69818272T2 (OSRAM)
DK (1) DK1003560T3 (OSRAM)
ES (1) ES2212304T3 (OSRAM)
IL (1) IL133271A (OSRAM)
NO (1) NO315693B1 (OSRAM)
NZ (1) NZ502029A (OSRAM)
PT (1) PT1003560E (OSRAM)
WO (1) WO1998055154A1 (OSRAM)

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US7238338B1 (en) * 2001-06-22 2007-07-03 Triumf System and method for the large scale labeling of compounds with radiohalogens
US7344702B2 (en) 2004-02-13 2008-03-18 Bristol-Myers Squibb Pharma Company Contrast agents for myocardial perfusion imaging
WO2003105762A2 (en) * 2002-06-14 2003-12-24 Actinium Pharmaceuticals Ltd. Treating disease using radium-225
US7018614B2 (en) * 2002-11-05 2006-03-28 Eastern Isotopes, Inc. Stabilization of radiopharmaceuticals labeled with 18-F
EP1575516B1 (en) 2002-11-26 2012-05-30 Abbott Biotherapeutics Corp. Chimeric and humanized antibodies to alpha5 beta1 integrin that modulate angiogenesis
EP1444990A1 (en) * 2003-02-07 2004-08-11 Amersham plc Improved Radiometal Complex Compositions
US7485283B2 (en) * 2004-04-28 2009-02-03 Lantheus Medical Imaging Contrast agents for myocardial perfusion imaging
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DK1851200T3 (da) 2005-02-25 2014-04-14 Tetralogic Pharm Corp Dimere iap-inhibitorer
JP2009509128A (ja) * 2005-08-09 2009-03-05 テトラロジック ファーマシューティカルズ コーポレーション 増殖性疾患の治療
US20100256046A1 (en) * 2009-04-03 2010-10-07 Tetralogic Pharmaceuticals Corporation Treatment of proliferative disorders
US20100056495A1 (en) * 2006-07-24 2010-03-04 Tetralogic Pharmaceuticals Corporation Dimeric iap inhibitors
WO2008014238A2 (en) * 2006-07-24 2008-01-31 Tetralogic Pharmaceuticals Corporation Dimeric iap inhibitors
CL2007002167A1 (es) * 2006-07-24 2009-01-23 Tetralogic Pharm Corp Compuestos derivados de indol, antagonistas iap; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto en el tratamiento de cancer.
JP5452223B2 (ja) * 2006-07-24 2014-03-26 テトラロジック ファーマシューティカルズ コーポレーション Ｉａｐ阻害剤
WO2008014240A2 (en) * 2006-07-24 2008-01-31 Tetralogic Pharmaceuticals Corporation Dimeric iap inhibitors
KR101408680B1 (ko) 2007-01-26 2014-06-17 가부시키가이샤 폴라 파마 의약 조성물
US8367052B2 (en) 2007-03-26 2013-02-05 General Regeneratives Holdings Inc. Methods for promoting protection and regeneration of bone marrow using CXCL9 and anti-CXCL9 antibodies
WO2009110984A2 (en) * 2008-02-29 2009-09-11 Lantheus Medical Imaging, Inc. Contrast agents for applications including perfusion imaging
RU2011124527A (ru) * 2008-11-17 2012-12-27 Дженентек, Инк. Способ и композиция для уменьшения агрегации макромолекулы в физиологических условиях
ES2770364T3 (es) 2009-04-15 2020-07-01 Lantheus Medical Imaging Inc Estabilización de composiciones radiofarmacéuticas utilizando ácido ascórbico
US8283372B2 (en) * 2009-07-02 2012-10-09 Tetralogic Pharmaceuticals Corp. 2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic
RU2631500C2 (ru) 2010-02-08 2017-09-25 Лантеус Медикал Имаджинг, Инк. Способы и устройство для синтезирования радиофармацевтических препаратов и их промежуточных продуктов
GB201013808D0 (en) * 2010-08-18 2010-09-29 Ge Healthcare Ltd Peptide radiotracer compositions
AU2013203000B9 (en) 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
CN105377287A (zh) * 2013-02-15 2016-03-02 托马斯杰弗逊大学 用于肿瘤成像的试剂盒
GB201314936D0 (en) 2013-08-21 2013-10-02 Ge Healthcare Ltd Radiolabelling method
GB201322456D0 (en) 2013-12-18 2014-02-05 Ge Healthcare Ltd Radiotracer compositions and methods
WO2015109246A1 (en) * 2014-01-17 2015-07-23 Repligen Corporation Sterilizing chromatography columns
IL237852A0 (en) 2015-03-19 2016-03-24 Yeda Res & Dev Antibodies against amphigoline, medical preparations containing them and their use
TWI799366B (zh) * 2015-09-15 2023-04-21 美商建南德克公司 胱胺酸結骨架平臺
HUE071169T2 (hu) * 2016-03-07 2025-08-28 Actinium Pharmaceuticals Inc Stabilizált, radioaktívan jelölt anti-CD45 immunglobulin-készítmények
WO2019089544A1 (en) 2017-11-01 2019-05-09 Tufts Medical Center, Inc. Bispecific antibody constructs and methods of use
US12599669B2 (en) 2019-04-23 2026-04-14 Amgen Inc. Use of low molecular weight polyvinylpyrrolidone (PVP) to reduce viscosity of high concentration protein formulations
US12043671B2 (en) 2021-06-16 2024-07-23 Gundersen Lutheran Medical Foundation, Inc. Antibodies targeting an amphiregulin-derived cell surface neo-epitope
CN121532218A (zh) 2023-06-16 2026-02-13 普罗热尼奇制药公司 前列腺特异性膜抗原（psma）放射性标记抑制剂[18f]dcfpyl的改进的合成

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CA2105402C (en) * 1992-04-30 2000-04-04 Roger M. Price Radiolabelled compound formulations
EP0622082A4 (en) * 1992-07-28 1996-12-04 Toray Industries IMMUNE COMPLEX.
US5595721A (en) * 1993-09-16 1997-01-21 Coulter Pharmaceutical, Inc. Radioimmunotherapy of lymphoma using anti-CD20
US5961955A (en) * 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope

Also Published As

Publication number Publication date
EP1003560B1 (en) 2003-09-17
JP2002516612A (ja) 2002-06-04
AU8057098A (en) 1998-12-21
DE69818272D1 (de) 2003-10-23
NZ502029A (en) 2001-12-21
NO995906D0 (no) 1999-12-02
DK1003560T3 (da) 2003-12-01
DE69818272T2 (de) 2004-07-01
NO995906L (no) 1999-12-03
CA2290987A1 (en) 1998-12-10
NO315693B1 (no) 2003-10-13
US6338835B1 (en) 2002-01-15
ES2212304T3 (es) 2004-07-16
EP1003560A1 (en) 2000-05-31
AU743823B2 (en) 2002-02-07
WO1998055154A9 (en) 1999-04-08
PT1003560E (pt) 2004-02-27
IL133271A (en) 2004-06-01
IL133271A0 (en) 2001-04-30
JP4291417B2 (ja) 2009-07-08
WO1998055154A1 (en) 1998-12-10
US5961955A (en) 1999-10-05

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