SE8103594L - N-(vinblastin-23-oyl)aminosyraderivat - Google Patents

N-(vinblastin-23-oyl)aminosyraderivat

Info

Publication number
SE8103594L
SE8103594L SE8103594A SE8103594A SE8103594L SE 8103594 L SE8103594 L SE 8103594L SE 8103594 A SE8103594 A SE 8103594A SE 8103594 A SE8103594 A SE 8103594A SE 8103594 L SE8103594 L SE 8103594L
Authority
SE
Sweden
Prior art keywords
vinblastine
amino acid
acid derivatives
oyl
derivatives
Prior art date
Application number
SE8103594A
Other languages
English (en)
Inventor
A B L Trouet
K S B Rao
J A A Hannart
Original Assignee
Omnichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU82514A external-priority patent/LU82514A1/fr
Priority claimed from LU83034A external-priority patent/LU83034A1/fr
Application filed by Omnichem Sa filed Critical Omnichem Sa
Publication of SE8103594L publication Critical patent/SE8103594L/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE8103594A 1980-06-10 1981-06-09 N-(vinblastin-23-oyl)aminosyraderivat SE8103594L (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU82514A LU82514A1 (fr) 1980-06-10 1980-06-10 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
LU83034A LU83034A1 (fr) 1980-12-23 1980-12-23 Derives n-(vinblastinoyl-23) d'acides amines et de peptides, leur preparation et leur application therapeutique

Publications (1)

Publication Number Publication Date
SE8103594L true SE8103594L (sv) 1981-12-11

Family

ID=26640267

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8103594A SE8103594L (sv) 1980-06-10 1981-06-09 N-(vinblastin-23-oyl)aminosyraderivat

Country Status (21)

Country Link
US (1) US4388305A (sv)
EP (1) EP0041935B1 (sv)
AT (2) AT390793B (sv)
AU (1) AU541747B2 (sv)
CA (1) CA1196326A (sv)
DD (1) DD160417A5 (sv)
DE (2) DE3122479A1 (sv)
DK (1) DK160614C (sv)
ES (1) ES502644A0 (sv)
FR (1) FR2483926A1 (sv)
GB (1) GB2078730A (sv)
GR (1) GR74565B (sv)
HU (1) HU185261B (sv)
IE (1) IE51403B1 (sv)
IL (1) IL63038A0 (sv)
IT (1) IT1144601B (sv)
NL (1) NL8102802A (sv)
NZ (1) NZ197299A (sv)
OA (1) OA06421A (sv)
PT (1) PT73161B (sv)
SE (1) SE8103594L (sv)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639456A (en) * 1980-06-10 1987-01-27 Omnichem S.A. Vinblastin-23-oyl amino acid derivatives
LU83822A1 (fr) * 1981-12-08 1983-09-01 Omnichem Sa Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
IT1170152B (it) * 1982-07-19 1987-06-03 Lilly Co Eli Miglioramenti a o riguardanti formulazioni di vinca-alcaloidi
DK167984A (da) * 1983-03-30 1984-10-01 Lilly Industries Ltd Alkaloidderivater
GR81790B (sv) * 1983-04-29 1984-12-12 Omnichem Sa
US4667030A (en) * 1985-06-17 1987-05-19 Eli Lilly And Company Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids
US4675400A (en) * 1985-06-17 1987-06-23 Eli Lilly And Company Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids
FI860456A (fi) * 1985-07-16 1987-01-17 Huhtamaeki Oy Laeaeketehdas Le Bis-indolalkaloiders proteinkonjugat, bis-indolalkaloider, deras framstaellning och anvaendning.
EP0232693A3 (fr) * 1985-12-16 1988-04-06 La Region Wallonne Conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques les contenant
CA1335686C (fr) * 1986-01-13 1995-05-23 Rao K. S. P. Bhushana Vinblastine et composition pharmaceutique les contenant
ES2045092T3 (es) * 1987-11-11 1994-01-16 Akzo Nv Un procedimiento de manufactura de un producto farmaceutico para tratamiento de cancer.
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2626882B1 (fr) * 1988-02-08 1991-11-08 Ire Celltarg Sa Conjugues de derives de vinca comportant une chaine detergente en position c-3
US4980343A (en) * 1988-10-27 1990-12-25 Bayer Aktiengesellschaft Aminooxodihydroisoindoloquinazoline carcinostatic agents
US5043336A (en) * 1990-04-03 1991-08-27 Eli Lilly And Company Cyclic imide derivatives of 4-desacetyl VLB c-3 carboxhydrazide
US5043340A (en) * 1990-04-03 1991-08-27 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxhydrazide
US6143864A (en) * 1994-06-28 2000-11-07 Merck & Co., Inc. Peptides
US5599686A (en) * 1994-06-28 1997-02-04 Merck & Co., Inc. Peptides
US5866679A (en) * 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
BE1008581A3 (fr) * 1994-08-19 1996-06-04 Wallone Region Prodrogues, composition pharmaceutique les comprenant et leur utilisation.
CA2203622C (en) * 1994-08-19 2011-11-01 Andre Trouet Compounds, pharmaceutical composition and diagnostic device comprising them and their use
US5998362A (en) * 1996-09-12 1999-12-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6127333A (en) * 1997-07-10 2000-10-03 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6391305B1 (en) 1997-09-10 2002-05-21 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
AU5240999A (en) * 1998-07-31 2000-02-21 Goldsmith Seeds Inc. Trimeric and polymeric alkaloids
DE19842416A1 (de) * 1998-09-16 2000-04-13 Max Planck Gesellschaft Sekundäre Amine zur Prävention und Therapie von Erkrankungen, die durch Oxidationsprozesse verursacht oder verstärkt werden
US7425541B2 (en) * 1998-12-11 2008-09-16 Medarex, Inc. Enzyme-cleavable prodrug compounds
CA2413149A1 (en) 2000-06-14 2001-12-20 Medarex, Inc. Prodrug compounds with isoleucine
US20030232760A1 (en) * 2001-09-21 2003-12-18 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
AU2004296191B2 (en) * 2003-12-04 2010-10-28 Albany Molecular Research, Inc. Vinca derivatives
US7235564B2 (en) * 2003-12-04 2007-06-26 Amr Technology, Inc. Vinorelbine derivatives
US8039453B2 (en) * 2006-09-12 2011-10-18 Albany Molecular Research, Inc. Vinca derivatives
WO2008033935A2 (en) * 2006-09-12 2008-03-20 Amr Technology, Inc. Vinorelbine derivatives
KR20230038457A (ko) 2020-06-10 2023-03-20 알리고스 테라퓨틱스 인코포레이티드 코로나바이러스, 피코르나바이러스 및 노로바이러스 감염을 치료하기 위한 항바이러스 화합물
AU2022306289A1 (en) 2021-07-09 2024-01-18 Aligos Therapeutics, Inc. Anti-viral compounds
US12065428B2 (en) 2021-09-17 2024-08-20 Aligos Therapeutics, Inc. Anti-viral compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3387001A (en) * 1964-10-19 1968-06-04 Lilly Co Eli Novel aminoacyl esters of desacetyl vincaleukoblastine
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
GR69783B (sv) * 1976-09-08 1982-07-07 Lilly Co Eli
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids

Also Published As

Publication number Publication date
DK250181A (da) 1981-12-11
US4388305A (en) 1983-06-14
NZ197299A (en) 1985-10-11
DE3166150D1 (en) 1984-10-25
NL8102802A (nl) 1982-01-04
HU185261B (en) 1984-12-28
ES8203385A1 (es) 1982-04-01
IT8167782A0 (it) 1981-06-08
ATA253881A (de) 1989-12-15
AU7126281A (en) 1981-12-17
AT390793B (de) 1990-06-25
IE51403B1 (en) 1986-12-24
DK160614C (da) 1991-09-23
PT73161A (fr) 1981-07-01
CA1196326A (en) 1985-11-05
DE3122479A1 (de) 1982-06-16
IL63038A0 (en) 1981-09-13
PT73161B (fr) 1982-07-16
DK160614B (da) 1991-04-02
DD160417A5 (de) 1983-07-27
EP0041935B1 (fr) 1984-09-19
ATE9475T1 (de) 1984-10-15
IE811275L (en) 1981-12-10
FR2483926A1 (fr) 1981-12-11
OA06421A (fr) 1981-09-30
IT1144601B (it) 1986-10-29
ES502644A0 (es) 1982-04-01
GB2078730A (en) 1982-01-13
FR2483926B1 (sv) 1983-07-29
GR74565B (sv) 1984-06-29
EP0041935A1 (fr) 1981-12-16
AU541747B2 (en) 1985-01-17

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