DK160614C - Analogifremgangsmaade til fremstilling af vinblastinderivater og farmaceutisk acceptable salte deraf - Google Patents

Analogifremgangsmaade til fremstilling af vinblastinderivater og farmaceutisk acceptable salte deraf

Info

Publication number
DK160614C
DK160614C DK250181A DK250181A DK160614C DK 160614 C DK160614 C DK 160614C DK 250181 A DK250181 A DK 250181A DK 250181 A DK250181 A DK 250181A DK 160614 C DK160614 C DK 160614C
Authority
DK
Denmark
Prior art keywords
preparation
wine
analogue
blast
ingredients
Prior art date
Application number
DK250181A
Other languages
English (en)
Other versions
DK160614B (da
DK250181A (da
Inventor
Andre Benoit Leon Trouet
Kandukuri Sivaprasada Bush Rao
Jean Alfred Alphonse Hannart
Original Assignee
Omnichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU82514A external-priority patent/LU82514A1/fr
Priority claimed from LU83034A external-priority patent/LU83034A1/fr
Application filed by Omnichem Sa filed Critical Omnichem Sa
Publication of DK250181A publication Critical patent/DK250181A/da
Publication of DK160614B publication Critical patent/DK160614B/da
Application granted granted Critical
Publication of DK160614C publication Critical patent/DK160614C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK250181A 1980-06-10 1981-06-09 Analogifremgangsmaade til fremstilling af vinblastinderivater og farmaceutisk acceptable salte deraf DK160614C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
LU82514A LU82514A1 (fr) 1980-06-10 1980-06-10 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
LU82514 1980-06-10
LU83034A LU83034A1 (fr) 1980-12-23 1980-12-23 Derives n-(vinblastinoyl-23) d'acides amines et de peptides, leur preparation et leur application therapeutique
LU83034 1980-12-23

Publications (3)

Publication Number Publication Date
DK250181A DK250181A (da) 1981-12-11
DK160614B DK160614B (da) 1991-04-02
DK160614C true DK160614C (da) 1991-09-23

Family

ID=26640267

Family Applications (1)

Application Number Title Priority Date Filing Date
DK250181A DK160614C (da) 1980-06-10 1981-06-09 Analogifremgangsmaade til fremstilling af vinblastinderivater og farmaceutisk acceptable salte deraf

Country Status (21)

Country Link
US (1) US4388305A (da)
EP (1) EP0041935B1 (da)
AT (2) AT390793B (da)
AU (1) AU541747B2 (da)
CA (1) CA1196326A (da)
DD (1) DD160417A5 (da)
DE (2) DE3122479A1 (da)
DK (1) DK160614C (da)
ES (1) ES8203385A1 (da)
FR (1) FR2483926A1 (da)
GB (1) GB2078730A (da)
GR (1) GR74565B (da)
HU (1) HU185261B (da)
IE (1) IE51403B1 (da)
IL (1) IL63038A0 (da)
IT (1) IT1144601B (da)
NL (1) NL8102802A (da)
NZ (1) NZ197299A (da)
OA (1) OA06421A (da)
PT (1) PT73161B (da)
SE (1) SE8103594L (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU83822A1 (fr) * 1981-12-08 1983-09-01 Omnichem Sa Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
US4639456A (en) * 1980-06-10 1987-01-27 Omnichem S.A. Vinblastin-23-oyl amino acid derivatives
IT1170152B (it) * 1982-07-19 1987-06-03 Lilly Co Eli Miglioramenti a o riguardanti formulazioni di vinca-alcaloidi
EP0123441B1 (en) * 1983-03-30 1990-10-03 Lilly Industries Limited Vincaleukoblastine derivatives
GR81790B (da) * 1983-04-29 1984-12-12 Omnichem Sa
US4675400A (en) * 1985-06-17 1987-06-23 Eli Lilly And Company Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids
US4667030A (en) * 1985-06-17 1987-05-19 Eli Lilly And Company Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids
FI860456A (fi) * 1985-07-16 1987-01-17 Huhtamaeki Oy Laeaeketehdas Le Bis-indolalkaloiders proteinkonjugat, bis-indolalkaloider, deras framstaellning och anvaendning.
EP0232693A3 (fr) * 1985-12-16 1988-04-06 La Region Wallonne Conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques les contenant
JPH075608B2 (ja) * 1986-01-13 1995-01-25 イ−ル−セルタ−ク ソシエテ アノニム ビンブラスチン誘導体
DE3867039D1 (de) * 1987-11-11 1992-01-30 Akzo Nv Vincristin enthaltendes produkt.
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2626882B1 (fr) * 1988-02-08 1991-11-08 Ire Celltarg Sa Conjugues de derives de vinca comportant une chaine detergente en position c-3
US4980343A (en) * 1988-10-27 1990-12-25 Bayer Aktiengesellschaft Aminooxodihydroisoindoloquinazoline carcinostatic agents
US5043336A (en) * 1990-04-03 1991-08-27 Eli Lilly And Company Cyclic imide derivatives of 4-desacetyl VLB c-3 carboxhydrazide
US5043340A (en) * 1990-04-03 1991-08-27 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxhydrazide
US5866679A (en) * 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
US5599686A (en) * 1994-06-28 1997-02-04 Merck & Co., Inc. Peptides
US6143864A (en) * 1994-06-28 2000-11-07 Merck & Co., Inc. Peptides
BE1008581A3 (fr) * 1994-08-19 1996-06-04 Wallone Region Prodrogues, composition pharmaceutique les comprenant et leur utilisation.
AU694546C (en) * 1994-08-19 2001-09-06 La Region Wallonne Compounds, pharmaceutical composition and diagnostic device comprising same and their use
US5998362A (en) * 1996-09-12 1999-12-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6127333A (en) * 1997-07-10 2000-10-03 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6391305B1 (en) 1997-09-10 2002-05-21 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
WO2000006582A1 (en) * 1998-07-31 2000-02-10 Goldsmith Seeds, Inc. Trimeric and polymeric alkaloids
DE19842416A1 (de) * 1998-09-16 2000-04-13 Max Planck Gesellschaft Sekundäre Amine zur Prävention und Therapie von Erkrankungen, die durch Oxidationsprozesse verursacht oder verstärkt werden
US7425541B2 (en) * 1998-12-11 2008-09-16 Medarex, Inc. Enzyme-cleavable prodrug compounds
JP2004510702A (ja) 2000-06-14 2004-04-08 メダレックス，インコーポレイティド イソロイシンを有するプロドラッグ化合物
US20030232760A1 (en) * 2001-09-21 2003-12-18 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
EP1694330A4 (en) * 2003-12-04 2009-06-24 Amr Technology Inc DERIVATIVES OF VINORELBINE
US7238704B2 (en) * 2003-12-04 2007-07-03 Amr Technology, Inc. Vinca derivatives
US8039453B2 (en) * 2006-09-12 2011-10-18 Albany Molecular Research, Inc. Vinca derivatives
US20080125451A1 (en) * 2006-09-12 2008-05-29 Amr Technology, Inc. Vinorelbine derivatives
KR20230038457A (ko) 2020-06-10 2023-03-20 알리고스 테라퓨틱스 인코포레이티드 코로나바이러스, 피코르나바이러스 및 노로바이러스 감염을 치료하기 위한 항바이러스 화합물
IL309732A (en) 2021-07-09 2024-02-01 Aligos Therapeutics Inc Antiviral compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3387001A (en) * 1964-10-19 1968-06-04 Lilly Co Eli Novel aminoacyl esters of desacetyl vincaleukoblastine
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
GR69783B (da) * 1976-09-08 1982-07-07 Lilly Co Eli
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids

Also Published As

Publication number Publication date
AU7126281A (en) 1981-12-17
FR2483926A1 (fr) 1981-12-11
HU185261B (en) 1984-12-28
ATE9475T1 (de) 1984-10-15
IE51403B1 (en) 1986-12-24
IT8167782A0 (it) 1981-06-08
ES502644A0 (es) 1982-04-01
DE3166150D1 (en) 1984-10-25
GR74565B (da) 1984-06-29
AU541747B2 (en) 1985-01-17
DD160417A5 (de) 1983-07-27
CA1196326A (en) 1985-11-05
GB2078730A (en) 1982-01-13
PT73161B (fr) 1982-07-16
SE8103594L (sv) 1981-12-11
DE3122479A1 (de) 1982-06-16
ES8203385A1 (es) 1982-04-01
OA06421A (fr) 1981-09-30
AT390793B (de) 1990-06-25
EP0041935A1 (fr) 1981-12-16
PT73161A (fr) 1981-07-01
NL8102802A (nl) 1982-01-04
IT1144601B (it) 1986-10-29
ATA253881A (de) 1989-12-15
FR2483926B1 (da) 1983-07-29
DK160614B (da) 1991-04-02
IL63038A0 (en) 1981-09-13
NZ197299A (en) 1985-10-11
IE811275L (en) 1981-12-10
EP0041935B1 (fr) 1984-09-19
US4388305A (en) 1983-06-14
DK250181A (da) 1981-12-11

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