IT8167782A0 - Derivati della vinblastina procedimento per la loro preparazione e composizioni farmaceutiche contenenti tali derivati - Google Patents

Derivati della vinblastina procedimento per la loro preparazione e composizioni farmaceutiche contenenti tali derivati

Info

Publication number
IT8167782A0
IT8167782A0 IT8167782A IT6778281A IT8167782A0 IT 8167782 A0 IT8167782 A0 IT 8167782A0 IT 8167782 A IT8167782 A IT 8167782A IT 6778281 A IT6778281 A IT 6778281A IT 8167782 A0 IT8167782 A0 IT 8167782A0
Authority
IT
Italy
Prior art keywords
derivatives
preparation
pharmaceutical compositions
compositions containing
procedure
Prior art date
Application number
IT8167782A
Other languages
English (en)
Other versions
IT1144601B (it
Inventor
Benoit Leon Trouet Andre
Sivaprasada Bushana Kandukuri
Jean Alfred Alphonse Hannart
Original Assignee
Omnichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU82514A external-priority patent/LU82514A1/fr
Priority claimed from LU83034A external-priority patent/LU83034A1/fr
Application filed by Omnichem Sa filed Critical Omnichem Sa
Publication of IT8167782A0 publication Critical patent/IT8167782A0/it
Application granted granted Critical
Publication of IT1144601B publication Critical patent/IT1144601B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
IT67782/81A 1980-06-10 1981-06-08 Derivati della vinblastina procedimento per la loro preparazione e composizioni farmaceutiche contenenti tali derivati IT1144601B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU82514A LU82514A1 (fr) 1980-06-10 1980-06-10 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
LU83034A LU83034A1 (fr) 1980-12-23 1980-12-23 Derives n-(vinblastinoyl-23) d'acides amines et de peptides, leur preparation et leur application therapeutique

Publications (2)

Publication Number Publication Date
IT8167782A0 true IT8167782A0 (it) 1981-06-08
IT1144601B IT1144601B (it) 1986-10-29

Family

ID=26640267

Family Applications (1)

Application Number Title Priority Date Filing Date
IT67782/81A IT1144601B (it) 1980-06-10 1981-06-08 Derivati della vinblastina procedimento per la loro preparazione e composizioni farmaceutiche contenenti tali derivati

Country Status (21)

Country Link
US (1) US4388305A (it)
EP (1) EP0041935B1 (it)
AT (2) AT390793B (it)
AU (1) AU541747B2 (it)
CA (1) CA1196326A (it)
DD (1) DD160417A5 (it)
DE (2) DE3122479A1 (it)
DK (1) DK160614C (it)
ES (1) ES8203385A1 (it)
FR (1) FR2483926A1 (it)
GB (1) GB2078730A (it)
GR (1) GR74565B (it)
HU (1) HU185261B (it)
IE (1) IE51403B1 (it)
IL (1) IL63038A0 (it)
IT (1) IT1144601B (it)
NL (1) NL8102802A (it)
NZ (1) NZ197299A (it)
OA (1) OA06421A (it)
PT (1) PT73161B (it)
SE (1) SE8103594L (it)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU83822A1 (fr) * 1981-12-08 1983-09-01 Omnichem Sa Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
US4639456A (en) * 1980-06-10 1987-01-27 Omnichem S.A. Vinblastin-23-oyl amino acid derivatives
IT1170152B (it) * 1982-07-19 1987-06-03 Lilly Co Eli Miglioramenti a o riguardanti formulazioni di vinca-alcaloidi
GR79898B (it) * 1983-03-30 1984-10-31 Lilly Industries Ltd
ATE64396T1 (de) * 1983-04-29 1991-06-15 Omnichem Sa Konjugierte vinblastin-verbindungen und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
US4675400A (en) * 1985-06-17 1987-06-23 Eli Lilly And Company Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids
US4667030A (en) * 1985-06-17 1987-05-19 Eli Lilly And Company Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids
FI860456A (fi) * 1985-07-16 1987-01-17 Huhtamaeki Oy Laeaeketehdas Le Bis-indolalkaloiders proteinkonjugat, bis-indolalkaloider, deras framstaellning och anvaendning.
EP0232693A3 (fr) * 1985-12-16 1988-04-06 La Region Wallonne Conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques les contenant
EP0233101A1 (fr) * 1986-01-13 1987-08-19 Ire-Celltarg S.A. Dérivés de vinblastine et composition pharmaceutique les contenant
DE3867039D1 (de) * 1987-11-11 1992-01-30 Akzo Nv Vincristin enthaltendes produkt.
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2626882B1 (fr) * 1988-02-08 1991-11-08 Ire Celltarg Sa Conjugues de derives de vinca comportant une chaine detergente en position c-3
US4980343A (en) * 1988-10-27 1990-12-25 Bayer Aktiengesellschaft Aminooxodihydroisoindoloquinazoline carcinostatic agents
US5043340A (en) * 1990-04-03 1991-08-27 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxhydrazide
US5043336A (en) * 1990-04-03 1991-08-27 Eli Lilly And Company Cyclic imide derivatives of 4-desacetyl VLB c-3 carboxhydrazide
US6143864A (en) * 1994-06-28 2000-11-07 Merck & Co., Inc. Peptides
US5866679A (en) * 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
US5599686A (en) * 1994-06-28 1997-02-04 Merck & Co., Inc. Peptides
BE1008581A3 (fr) * 1994-08-19 1996-06-04 Wallone Region Prodrogues, composition pharmaceutique les comprenant et leur utilisation.
EP0769967B1 (fr) * 1994-08-19 2007-12-12 La Region Wallonne Conjugues comprenant un agent antitumoral et leur utilisation
US5998362A (en) * 1996-09-12 1999-12-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6127333A (en) * 1997-07-10 2000-10-03 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6391305B1 (en) 1997-09-10 2002-05-21 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
WO2000006582A1 (en) * 1998-07-31 2000-02-10 Goldsmith Seeds, Inc. Trimeric and polymeric alkaloids
DE19842416A1 (de) * 1998-09-16 2000-04-13 Max Planck Gesellschaft Sekundäre Amine zur Prävention und Therapie von Erkrankungen, die durch Oxidationsprozesse verursacht oder verstärkt werden
US7425541B2 (en) * 1998-12-11 2008-09-16 Medarex, Inc. Enzyme-cleavable prodrug compounds
WO2001095943A2 (en) 2000-06-14 2001-12-20 Medarex, Inc. Prodrug compounds with an oligopeptide having an isoleucine residue
US20030232760A1 (en) * 2001-09-21 2003-12-18 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
NZ547370A (en) * 2003-12-04 2010-09-30 Amr Technology Inc Vinca derivatives
WO2005055943A2 (en) * 2003-12-04 2005-06-23 Amr Technology, Inc. Vinorelbine derivatives
US20080125451A1 (en) * 2006-09-12 2008-05-29 Amr Technology, Inc. Vinorelbine derivatives
WO2008033930A2 (en) * 2006-09-12 2008-03-20 Amr Technology, Inc. Vinca derivatives
KR20230038457A (ko) 2020-06-10 2023-03-20 알리고스 테라퓨틱스 인코포레이티드 코로나바이러스, 피코르나바이러스 및 노로바이러스 감염을 치료하기 위한 항바이러스 화합물
PE20240775A1 (es) 2021-07-09 2024-04-17 Aligos Therapeutics Inc Compuestos antivirales

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3387001A (en) * 1964-10-19 1968-06-04 Lilly Co Eli Novel aminoacyl esters of desacetyl vincaleukoblastine
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
GR69783B (it) * 1976-09-08 1982-07-07 Lilly Co Eli
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids

Also Published As

Publication number Publication date
OA06421A (fr) 1981-09-30
AU541747B2 (en) 1985-01-17
FR2483926B1 (it) 1983-07-29
NL8102802A (nl) 1982-01-04
DK160614C (da) 1991-09-23
ES502644A0 (es) 1982-04-01
DK250181A (da) 1981-12-11
ATA253881A (de) 1989-12-15
DK160614B (da) 1991-04-02
IE811275L (en) 1981-12-10
US4388305A (en) 1983-06-14
IT1144601B (it) 1986-10-29
FR2483926A1 (fr) 1981-12-11
NZ197299A (en) 1985-10-11
AT390793B (de) 1990-06-25
SE8103594L (sv) 1981-12-11
AU7126281A (en) 1981-12-17
ATE9475T1 (de) 1984-10-15
PT73161A (fr) 1981-07-01
DE3166150D1 (en) 1984-10-25
EP0041935A1 (fr) 1981-12-16
DD160417A5 (de) 1983-07-27
EP0041935B1 (fr) 1984-09-19
PT73161B (fr) 1982-07-16
ES8203385A1 (es) 1982-04-01
HU185261B (en) 1984-12-28
IL63038A0 (en) 1981-09-13
GR74565B (it) 1984-06-29
GB2078730A (en) 1982-01-13
CA1196326A (en) 1985-11-05
DE3122479A1 (de) 1982-06-16
IE51403B1 (en) 1986-12-24

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