ATE249845T1 - Strahlenschutzsubstanz fur radioisotopen markierte peptiden - Google Patents

Strahlenschutzsubstanz fur radioisotopen markierte peptiden

Info

Publication number
ATE249845T1
ATE249845T1 AT98928875T AT98928875T ATE249845T1 AT E249845 T1 ATE249845 T1 AT E249845T1 AT 98928875 T AT98928875 T AT 98928875T AT 98928875 T AT98928875 T AT 98928875T AT E249845 T1 ATE249845 T1 AT E249845T1
Authority
AT
Austria
Prior art keywords
radiation protection
labeled peptides
radioisotope labeled
protection substance
radiolabeled
Prior art date
Application number
AT98928875T
Other languages
English (en)
Inventor
Dan Shochat
Albert S K Chan
Michael J Buckley
David Colcher
Original Assignee
Coulter Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter Pharm Inc filed Critical Coulter Pharm Inc
Application granted granted Critical
Publication of ATE249845T1 publication Critical patent/ATE249845T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT98928875T 1997-06-03 1998-06-03 Strahlenschutzsubstanz fur radioisotopen markierte peptiden ATE249845T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4838797P 1997-06-03 1997-06-03
US08/918,525 US5961955A (en) 1997-06-03 1997-08-21 Radioprotectant for peptides labeled with radioisotope
PCT/US1998/011428 WO1998055154A1 (en) 1997-06-03 1998-06-03 Radioprotectant for peptides labeled with radioisotope

Publications (1)

Publication Number Publication Date
ATE249845T1 true ATE249845T1 (de) 2003-10-15

Family

ID=26726075

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98928875T ATE249845T1 (de) 1997-06-03 1998-06-03 Strahlenschutzsubstanz fur radioisotopen markierte peptiden

Country Status (14)

Country Link
US (2) US5961955A (de)
EP (1) EP1003560B1 (de)
JP (1) JP4291417B2 (de)
AT (1) ATE249845T1 (de)
AU (1) AU743823B2 (de)
CA (1) CA2290987A1 (de)
DE (1) DE69818272T2 (de)
DK (1) DK1003560T3 (de)
ES (1) ES2212304T3 (de)
IL (1) IL133271A (de)
NO (1) NO315693B1 (de)
NZ (1) NZ502029A (de)
PT (1) PT1003560E (de)
WO (1) WO1998055154A1 (de)

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KR100589568B1 (ko) 1998-06-02 2006-06-14 더 다우 케미칼 캄파니 근접조사요법용 방사성 요오드화 페놀류
US20020102208A1 (en) * 1999-03-01 2002-08-01 Paul Chinn Radiolabeling kit and binding assay
KR100330733B1 (ko) * 1999-11-30 2002-04-03 노광 폴리에틸렌글리콜포스페이트, 그의 합성방법 및 그를방사능보호제로 사용하는 방법
WO2002022000A2 (en) * 2000-09-15 2002-03-21 Sloan Kettering Institute For Cancer Research Targeted alpha particle therapy using actinium-225 conjugates
WO2002067859A2 (en) * 2001-02-26 2002-09-06 Bristol-Myers Squibb Pharma Company Ascorbic acid analogs for metalloradiopharmaceuticals
US6972324B2 (en) * 2001-05-18 2005-12-06 Boehringer Ingelheim Pharmaceuticals, Inc. Antibodies specific for CD44v6
US7238338B1 (en) * 2001-06-22 2007-07-03 Triumf System and method for the large scale labeling of compounds with radiohalogens
US7344702B2 (en) 2004-02-13 2008-03-18 Bristol-Myers Squibb Pharma Company Contrast agents for myocardial perfusion imaging
WO2003105762A2 (en) * 2002-06-14 2003-12-24 Actinium Pharmaceuticals Ltd. Treating disease using radium-225
US7018614B2 (en) * 2002-11-05 2006-03-28 Eastern Isotopes, Inc. Stabilization of radiopharmaceuticals labeled with 18-F
BR0316670A (pt) 2002-11-26 2005-10-11 Protein Design Labs Inc Anticorpos quiméricos e humanizados para integrina (alfa)5ß1 que modulam a angiogênese
EP1444990A1 (de) * 2003-02-07 2004-08-11 Amersham plc Verbesserte Radiometallkomplexzusammensetzungen
US7485283B2 (en) * 2004-04-28 2009-02-03 Lantheus Medical Imaging Contrast agents for myocardial perfusion imaging
AU2005274937B2 (en) 2004-07-15 2011-08-18 Medivir Ab IAP binding compounds
AU2006216450C1 (en) 2005-02-25 2013-01-10 Medivir Ab Dimeric IAP inhibitors
CA2617642A1 (en) * 2005-08-09 2007-02-22 Tetralogic Pharmaceuticals Corporation Treatment of proliferative disorders
US20100256046A1 (en) * 2009-04-03 2010-10-07 Tetralogic Pharmaceuticals Corporation Treatment of proliferative disorders
WO2008014236A1 (en) * 2006-07-24 2008-01-31 Tetralogic Pharmaceuticals Corporation Dimeric iap inhibitors
CL2007002166A1 (es) * 2006-07-24 2008-01-25 Tetralogic Pharm Corp Compuestos derivados de heterociclos de nitrogeno, antagonistas de los inhibidores de las proteinas de la apoptosis; sus composiciones farmaceuticas; y uso de dichos compuestos para el tratamiento del cancer.
WO2008014240A2 (en) * 2006-07-24 2008-01-31 Tetralogic Pharmaceuticals Corporation Dimeric iap inhibitors
US20100143499A1 (en) * 2006-07-24 2010-06-10 Tetralogic Pharmaceuticals Corporation Dimeric iap inhibitors
EP2409984A1 (de) * 2006-07-24 2012-01-25 Tetralogic Pharmaceuticals Corporation Dimere IAP-Antagonisten
KR101408680B1 (ko) 2007-01-26 2014-06-17 가부시키가이샤 폴라 파마 의약 조성물
EP2136832B1 (de) 2007-03-26 2015-09-02 General Regeneratives Limited Verfahren zur förderung des schutzes und der regeneration von knochenmark mit cxcl9 und anti-cxcl9-antikörpern
EP2257315B1 (de) 2008-02-29 2019-10-23 Lantheus Medical Imaging, Inc. Kontrastmittel für anwendungen einschliesslich perfusionsbildgebung
CN102281902B (zh) * 2008-11-17 2013-11-13 弗·哈夫曼-拉罗切有限公司 用于减少大分子在生理条件下聚集的方法和制剂
US9687571B2 (en) 2009-04-15 2017-06-27 Lantheus Medical Imaging, Inc. Stabilization of radiopharmaceutical compositions using ascorbic acid
US8283372B2 (en) 2009-07-02 2012-10-09 Tetralogic Pharmaceuticals Corp. 2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic
PT2534136T (pt) 2010-02-08 2017-12-15 Lantheus Medical Imaging Inc Métodos para sintetizar agentes de imagiologia, e seus intermediários
GB201013808D0 (en) * 2010-08-18 2010-09-29 Ge Healthcare Ltd Peptide radiotracer compositions
AU2013203000B9 (en) 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
AU2014216515A1 (en) * 2013-02-15 2015-10-08 Thomas Jefferson University Kit for tumor imaging
GB201314936D0 (en) 2013-08-21 2013-10-02 Ge Healthcare Ltd Radiolabelling method
GB201322456D0 (en) 2013-12-18 2014-02-05 Ge Healthcare Ltd Radiotracer compositions and methods
EP3094391A4 (de) * 2014-01-17 2017-09-20 Repligen Corporation Sterilisation von chromatografiesäulen
IL237852A0 (en) 2015-03-19 2016-03-24 Yeda Res & Dev Antibodies against amphigoline, medical preparations containing them and their use
EP3426305A4 (de) * 2016-03-07 2020-01-08 Actinium Pharmaceuticals, Inc. Stabilisierte radioaktiv markierte anti-cd45-immunglobulinzusammensetzungen
US11339221B2 (en) 2017-11-01 2022-05-24 Tufts Medical Center, Inc. Bispecific antibody constructs and methods of use

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US4421735A (en) * 1980-04-17 1983-12-20 The Massachusetts General Hospital Radiolabeled diagnostic compositions and method for making the same
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US4411881A (en) * 1982-07-12 1983-10-25 New England Nuclear Corporation Composition and method for stabilizing radiolabeled compounds using thiocarbonylated diethylenetriamines
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JP3117719B2 (ja) * 1992-04-30 2000-12-18 アマーシャム・インターナショナル・ピーエルシー 放射性標識化合物の配合物
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US5595721A (en) * 1993-09-16 1997-01-21 Coulter Pharmaceutical, Inc. Radioimmunotherapy of lymphoma using anti-CD20
US5961955A (en) * 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope

Also Published As

Publication number Publication date
JP2002516612A (ja) 2002-06-04
IL133271A0 (en) 2001-04-30
US6338835B1 (en) 2002-01-15
EP1003560A1 (de) 2000-05-31
DE69818272T2 (de) 2004-07-01
WO1998055154A9 (en) 1999-04-08
IL133271A (en) 2004-06-01
WO1998055154A1 (en) 1998-12-10
NO315693B1 (no) 2003-10-13
CA2290987A1 (en) 1998-12-10
ES2212304T3 (es) 2004-07-16
AU8057098A (en) 1998-12-21
NO995906D0 (no) 1999-12-02
NO995906L (no) 1999-12-03
PT1003560E (pt) 2004-02-27
DK1003560T3 (da) 2003-12-01
JP4291417B2 (ja) 2009-07-08
NZ502029A (en) 2001-12-21
AU743823B2 (en) 2002-02-07
EP1003560B1 (de) 2003-09-17
US5961955A (en) 1999-10-05
DE69818272D1 (de) 2003-10-23

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