ATE238051T1 - Vitamin e und seine ester zur verwendung in der lokale behandlung von schleimhauterkrankungen - Google Patents
Vitamin e und seine ester zur verwendung in der lokale behandlung von schleimhauterkrankungenInfo
- Publication number
- ATE238051T1 ATE238051T1 AT99926687T AT99926687T ATE238051T1 AT E238051 T1 ATE238051 T1 AT E238051T1 AT 99926687 T AT99926687 T AT 99926687T AT 99926687 T AT99926687 T AT 99926687T AT E238051 T1 ATE238051 T1 AT E238051T1
- Authority
- AT
- Austria
- Prior art keywords
- vitamin
- esters
- vulvitis
- topical treatment
- mucous membrane
- Prior art date
Links
- 230000000699 topical effect Effects 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 210000004400 mucous membrane Anatomy 0.000 title 1
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 150000003722 vitamin derivatives Chemical class 0.000 title 1
- 208000002003 vulvitis Diseases 0.000 abstract 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 2
- 206010036774 Proctitis Diseases 0.000 abstract 2
- 206010068172 Anal pruritus Diseases 0.000 abstract 1
- 208000004746 Atrophic Vaginitis Diseases 0.000 abstract 1
- 206010003693 Atrophic vulvovaginitis Diseases 0.000 abstract 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 abstract 1
- 208000034347 Faecal incontinence Diseases 0.000 abstract 1
- 208000005232 Glossitis Diseases 0.000 abstract 1
- 208000001688 Herpes Genitalis Diseases 0.000 abstract 1
- 206010028781 Nasal vestibulitis Diseases 0.000 abstract 1
- 208000003251 Pruritus Diseases 0.000 abstract 1
- 208000009544 Pruritus Ani Diseases 0.000 abstract 1
- 229930003427 Vitamin E Natural products 0.000 abstract 1
- 208000002399 aphthous stomatitis Diseases 0.000 abstract 1
- 201000007717 corneal ulcer Diseases 0.000 abstract 1
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 201000003079 ectropion Diseases 0.000 abstract 1
- 208000001780 epistaxis Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000003325 follicular Effects 0.000 abstract 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 1
- 201000004946 genital herpes Diseases 0.000 abstract 1
- 230000007803 itching Effects 0.000 abstract 1
- 206010023332 keratitis Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 210000002200 mouth mucosa Anatomy 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 201000010808 postmenopausal atrophic vaginitis Diseases 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
- 206010039083 rhinitis Diseases 0.000 abstract 1
- 208000003265 stomatitis Diseases 0.000 abstract 1
- 229940042585 tocopherol acetate Drugs 0.000 abstract 1
- 229940046009 vitamin E Drugs 0.000 abstract 1
- 235000019165 vitamin E Nutrition 0.000 abstract 1
- 239000011709 vitamin E Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Communicable Diseases (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Gynecology & Obstetrics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT98MI001586A ITMI981586A1 (it) | 1998-07-10 | 1998-07-10 | Vitamina e e suoi esteri per l'uso nel trattamento topico di patologie delle mucose |
| PCT/IB1999/001238 WO2000002554A1 (en) | 1998-07-10 | 1999-07-05 | Vitamin e and esters thereof for use in the topical treatment of mucosal pathologies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE238051T1 true ATE238051T1 (de) | 2003-05-15 |
Family
ID=11380415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99926687T ATE238051T1 (de) | 1998-07-10 | 1999-07-05 | Vitamin e und seine ester zur verwendung in der lokale behandlung von schleimhauterkrankungen |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1094807B1 (enExample) |
| JP (1) | JP2002520281A (enExample) |
| CN (1) | CN1135975C (enExample) |
| AT (1) | ATE238051T1 (enExample) |
| AU (1) | AU762860B2 (enExample) |
| BR (1) | BR9911945A (enExample) |
| CA (1) | CA2336990A1 (enExample) |
| CZ (1) | CZ301019B6 (enExample) |
| DE (1) | DE69907193T2 (enExample) |
| DK (1) | DK1094807T3 (enExample) |
| ES (1) | ES2196813T3 (enExample) |
| HU (1) | HU228921B1 (enExample) |
| IL (1) | IL140759A0 (enExample) |
| IT (1) | ITMI981586A1 (enExample) |
| NO (1) | NO20006719L (enExample) |
| NZ (1) | NZ509129A (enExample) |
| PL (1) | PL345500A1 (enExample) |
| PT (1) | PT1094807E (enExample) |
| RU (2) | RU2221561C2 (enExample) |
| SK (1) | SK284464B6 (enExample) |
| TR (2) | TR200100014T2 (enExample) |
| WO (1) | WO2000002554A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040077604A1 (en) | 2001-12-19 | 2004-04-22 | Lenard Lichtenberger | Method and compositions employing formulations of lecithin oils and nsaids for protecting the gastrointestinal tract and providingenhanced therapeutic activity |
| FR2819186A1 (fr) * | 2001-01-10 | 2002-07-12 | L M D | Cystine-voie orale-syndrome de l'oeil sec |
| FR2825088A1 (fr) * | 2001-05-25 | 2002-11-29 | Derma Dev | Nouveaux esters de tocopherol, leurs procedes d'obtention et leurs utilisations |
| US7485666B2 (en) * | 2004-06-17 | 2009-02-03 | Kimberly-Clark Worldwide, Inc. | Vaginal health products |
| US20080038316A1 (en) | 2004-10-01 | 2008-02-14 | Wong Vernon G | Conveniently implantable sustained release drug compositions |
| US9993558B2 (en) | 2004-10-01 | 2018-06-12 | Ramscor, Inc. | Sustained release eye drop formulations |
| US8541413B2 (en) * | 2004-10-01 | 2013-09-24 | Ramscor, Inc. | Sustained release eye drop formulations |
| RU2428973C2 (ru) * | 2005-03-03 | 2011-09-20 | Вайтал Хэлф Сайнсис Пти Лтд | Составы, обладающие липидопонижающими свойствами |
| JP5731980B2 (ja) * | 2008-10-09 | 2015-06-10 | ラムズコア， インコーポレイテッド | ドライアイ症候群の処置のための組成物および方法 |
| IT1394063B1 (it) * | 2009-05-11 | 2012-05-25 | Giuliani Spa | Composizione per uso oftalmico adatta al trattamento degli stati infiammatori dell'occhio e della sindrome dell'occhio secco |
| RU2540481C2 (ru) * | 2009-07-27 | 2015-02-10 | Сальваторе Троизи | Офтальмологический раствор для защиты внутренних структур глазного яблока от уф-а лучей или для лечения кератоконуса методом трансэпителиального кросс-линкинга |
| WO2013049749A2 (en) | 2011-09-29 | 2013-04-04 | Plx Pharma Inc. | pH DEPENDENT CARRIERS FOR TARGETED RELEASE OF PHARMACEUTICALS ALONG THE GASTROINTESTINAL TRACT, COMPOSITIONS THEREFROM, AND MAKING AND USING SAME |
| WO2013185024A1 (en) * | 2012-06-08 | 2013-12-12 | The Ohio State University | Treating burn and scar injury using tocotrienol |
| DE202014106007U1 (de) * | 2014-07-22 | 2015-07-23 | Bio.Lo.Ga. S.R.L. | Zusammensetzung zur Verwendung in der Vorbeugung und Behandlung allergischer Rhinitis |
| LT3209294T (lt) * | 2014-10-22 | 2019-10-25 | Bio Lo Ga Srl | Farmacinė kompozicija, skirta panaudoti nosies gleivinės trofizmo padidinimui |
| JP2018507895A (ja) * | 2015-03-18 | 2018-03-22 | バイオヌークス スイス エスエー | ヘルペスを処置するための方法において使用するためのジヒドロケルセチンを含む組成物 |
| JP2017119669A (ja) * | 2015-10-15 | 2017-07-06 | ロート製薬株式会社 | 異物感改善用眼科組成物 |
| WO2020053783A1 (en) * | 2018-09-12 | 2020-03-19 | Neilos S.r.l. | A composition for use in the prevention and/or treatment of epistaxis |
| IT202000003620A1 (it) | 2020-02-21 | 2021-08-21 | Hulka S R L | Uso di una formulazione per applicazione topica per il mantenimento dell’omeostasi vaginale |
| KR20220158031A (ko) | 2020-03-26 | 2022-11-29 | 피엘엑스 옵코 인코포레이티드 | pH 의존성 재구성이 가능한 제약 담체 및 그의 제조 및 사용 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59216812A (ja) * | 1983-05-26 | 1984-12-06 | Dowa Yakushiyou Kk | 頭髪育毛料 |
| JP2776837B2 (ja) * | 1988-08-11 | 1998-07-16 | 日本レダリー株式会社 | 消化性潰瘍治療剤 |
| US5032384A (en) * | 1989-01-27 | 1991-07-16 | Block Drug Company, Inc. | Compositions and method for the treatment of disease |
| SU1628281A3 (ru) * | 1989-03-30 | 1994-02-28 | Научно-производственная фирма "Флори" | Ранозаживляющее средство |
| IT1249711B (it) * | 1991-09-30 | 1995-03-09 | Boniscontro E Gazzone S R L | Composizioni farmaceutiche, per uso topico, contenenti "scavengers" di radicali liberi dell'ossigeno e antibatterici,indicate nella terapia dei tessuti superficiali. |
| JP2811036B2 (ja) * | 1992-05-26 | 1998-10-15 | 参天製薬株式会社 | ビタミンｅ点眼剤 |
| JP3551977B2 (ja) * | 1993-04-08 | 2004-08-11 | ライオン株式会社 | 安定なビタミンａ類及びビタミンｅ類可溶化点眼剤 |
| CN1039087C (zh) * | 1993-12-29 | 1998-07-15 | 昆明宏达实业有限总公司 | 妇科病治疗保健外用药物 |
| RU2125887C1 (ru) * | 1995-08-25 | 1999-02-10 | Владивостокский государственный медицинский университет | Способ приготовления липосомального интерферона |
| IT1282778B1 (it) * | 1996-05-31 | 1998-03-31 | Giorgio Panin | Vitamina "e" acetato quale prodotto per applicazione topica |
| JPH10109934A (ja) * | 1996-10-04 | 1998-04-28 | Sekisui Chem Co Ltd | 炎症性眼疾患用剤 |
| JPH10231243A (ja) * | 1997-02-20 | 1998-09-02 | Sekisui Chem Co Ltd | 粘膜炎症外用薬 |
-
1998
- 1998-07-10 IT IT98MI001586A patent/ITMI981586A1/it unknown
-
1999
- 1999-07-05 RU RU2001101122/15A patent/RU2221561C2/ru active
- 1999-07-05 TR TR2001/00014T patent/TR200100014T2/xx unknown
- 1999-07-05 DE DE69907193T patent/DE69907193T2/de not_active Expired - Lifetime
- 1999-07-05 CA CA002336990A patent/CA2336990A1/en not_active Abandoned
- 1999-07-05 DK DK99926687T patent/DK1094807T3/da active
- 1999-07-05 BR BR9911945-5A patent/BR9911945A/pt not_active Application Discontinuation
- 1999-07-05 TR TR2001/03710T patent/TR200103710T2/xx unknown
- 1999-07-05 NZ NZ509129A patent/NZ509129A/en not_active IP Right Cessation
- 1999-07-05 AU AU43858/99A patent/AU762860B2/en not_active Expired
- 1999-07-05 WO PCT/IB1999/001238 patent/WO2000002554A1/en not_active Ceased
- 1999-07-05 JP JP2000558814A patent/JP2002520281A/ja active Pending
- 1999-07-05 CN CNB998084328A patent/CN1135975C/zh not_active Expired - Lifetime
- 1999-07-05 AT AT99926687T patent/ATE238051T1/de active
- 1999-07-05 HU HU0102781A patent/HU228921B1/hu unknown
- 1999-07-05 PT PT99926687T patent/PT1094807E/pt unknown
- 1999-07-05 EP EP99926687A patent/EP1094807B1/en not_active Expired - Lifetime
- 1999-07-05 CZ CZ20010036A patent/CZ301019B6/cs unknown
- 1999-07-05 IL IL14075999A patent/IL140759A0/xx unknown
- 1999-07-05 SK SK35-2001A patent/SK284464B6/sk unknown
- 1999-07-05 ES ES99926687T patent/ES2196813T3/es not_active Expired - Lifetime
- 1999-07-05 PL PL99345500A patent/PL345500A1/xx not_active Application Discontinuation
-
2000
- 2000-12-29 NO NO20006719A patent/NO20006719L/no not_active Application Discontinuation
-
2003
- 2003-09-11 RU RU2003128023/15A patent/RU2003128023A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1094807B1 (en) | 2003-04-23 |
| ITMI981586A1 (it) | 2000-01-10 |
| NZ509129A (en) | 2003-10-31 |
| PL345500A1 (en) | 2001-12-17 |
| SK352001A3 (en) | 2001-06-11 |
| HUP0102781A2 (hu) | 2001-12-28 |
| PT1094807E (pt) | 2003-08-29 |
| TR200100014T2 (tr) | 2001-06-21 |
| RU2003128023A (ru) | 2005-04-10 |
| DK1094807T3 (da) | 2003-08-11 |
| JP2002520281A (ja) | 2002-07-09 |
| SK284464B6 (sk) | 2005-04-01 |
| WO2000002554A1 (en) | 2000-01-20 |
| AU4385899A (en) | 2000-02-01 |
| EP1094807A1 (en) | 2001-05-02 |
| CN1308531A (zh) | 2001-08-15 |
| BR9911945A (pt) | 2001-03-27 |
| IL140759A0 (en) | 2002-02-10 |
| DE69907193D1 (de) | 2003-05-28 |
| AU762860B2 (en) | 2003-07-10 |
| ES2196813T3 (es) | 2003-12-16 |
| DE69907193T2 (de) | 2004-04-08 |
| CZ200136A3 (cs) | 2001-08-15 |
| CN1135975C (zh) | 2004-01-28 |
| NO20006719D0 (no) | 2000-12-29 |
| CZ301019B6 (cs) | 2009-10-14 |
| HU228921B1 (en) | 2013-06-28 |
| ITMI981586A0 (it) | 1998-07-10 |
| RU2221561C2 (ru) | 2004-01-20 |
| NO20006719L (no) | 2001-02-16 |
| TR200103710T2 (tr) | 2002-06-21 |
| CA2336990A1 (en) | 2000-01-20 |
| HUP0102781A3 (en) | 2002-04-29 |
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