DE60114448D1 - Imidazolonderivate zur behandlung viraler krankheiten - Google Patents

Imidazolonderivate zur behandlung viraler krankheiten

Info

Publication number
DE60114448D1
DE60114448D1 DE60114448T DE60114448T DE60114448D1 DE 60114448 D1 DE60114448 D1 DE 60114448D1 DE 60114448 T DE60114448 T DE 60114448T DE 60114448 T DE60114448 T DE 60114448T DE 60114448 D1 DE60114448 D1 DE 60114448D1
Authority
DE
Germany
Prior art keywords
imidazolon
derivatives
treatment
viral diseases
viral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60114448T
Other languages
English (en)
Other versions
DE60114448T2 (de
Inventor
William Dymock
Stephen Jones
Herbert Merrett
Edward Parkes
John Parratt
Simon Walter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE60114448D1 publication Critical patent/DE60114448D1/de
Publication of DE60114448T2 publication Critical patent/DE60114448T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60114448T 2000-11-22 2001-11-12 Imidazolonderivate zur behandlung viraler krankheiten Expired - Fee Related DE60114448T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0028484.4A GB0028484D0 (en) 2000-11-22 2000-11-22 Imidazolone derivatives for the treatment of viral diseases
GB0028484 2000-11-22
PCT/EP2001/013069 WO2002042279A1 (en) 2000-11-22 2001-11-12 Imidazolone derivatives for the treatment of viral diseases

Publications (2)

Publication Number Publication Date
DE60114448D1 true DE60114448D1 (de) 2005-12-01
DE60114448T2 DE60114448T2 (de) 2006-07-06

Family

ID=9903671

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60114448T Expired - Fee Related DE60114448T2 (de) 2000-11-22 2001-11-12 Imidazolonderivate zur behandlung viraler krankheiten

Country Status (20)

Country Link
US (1) US6518293B2 (de)
EP (1) EP1341766B1 (de)
JP (1) JP2004514672A (de)
KR (1) KR100528760B1 (de)
CN (1) CN1633417A (de)
AR (1) AR035372A1 (de)
AT (1) ATE307805T1 (de)
AU (2) AU2002221842B2 (de)
BR (1) BR0115476A (de)
CA (1) CA2428461A1 (de)
DE (1) DE60114448T2 (de)
DK (1) DK1341766T3 (de)
ES (1) ES2251529T3 (de)
GB (1) GB0028484D0 (de)
MX (1) MXPA03004454A (de)
PA (1) PA8533301A1 (de)
PE (1) PE20020636A1 (de)
UY (1) UY27035A1 (de)
WO (1) WO2002042279A1 (de)
ZA (1) ZA200303690B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200423930A (en) * 2003-02-18 2004-11-16 Hoffmann La Roche Non-nucleoside reverse transcriptase inhibitors
JP2007532626A (ja) * 2004-04-14 2007-11-15 ファイザー・インク Ｈｉｖ治療用硫黄連結イミダゾール化合物
US20080176919A1 (en) * 2005-01-06 2008-07-24 Pfizer Inc Imidazole Derivatives As Enzyme Reverse Transcriptase Modulators
WO2008085008A1 (en) * 2007-01-11 2008-07-17 Mogam Biotechnology Research Institute T-cell inhibiting compounds and their use for the treatment of t-cell-mediated diseases
KR101110120B1 (ko) * 2009-10-28 2012-01-31 주식회사 케이아이테크놀로지 표지판 완충장치

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4345936A (en) * 1981-10-05 1982-08-24 Eli Lilly And Company Imidazoles, compositions and herbicidal method
TW235963B (de) 1992-01-16 1994-12-11 Shionogi & Co
WO1993015060A1 (en) 1992-01-22 1993-08-05 Nissan Chemical Industries, Ltd. Substituted pyrazole derivative and agrohorticultural bactericide
GB9222262D0 (en) 1992-10-23 1992-12-09 Merck Sharp & Dohme Therapeutic agents
US5612636A (en) * 1995-01-19 1997-03-18 Texas Instruments Incorporated Short circuit power optimization for CMOS circuits
US5612363A (en) 1995-06-02 1997-03-18 Berlex Laboratories, Inc. N,N-di(aryl) cyclic urea derivatives as anti-coagulants
US6046331A (en) * 1998-12-17 2000-04-04 Synaptic Pharmaceutical Corporation Imidazolones and their use in treating benign prostatic hyperplasia and other disorders

Also Published As

Publication number Publication date
EP1341766B1 (de) 2005-10-26
AU2002221842B2 (en) 2007-08-23
CN1633417A (zh) 2005-06-29
US6518293B2 (en) 2003-02-11
DK1341766T3 (da) 2006-02-20
JP2004514672A (ja) 2004-05-20
GB0028484D0 (en) 2001-01-10
US20020107272A1 (en) 2002-08-08
ES2251529T3 (es) 2006-05-01
PA8533301A1 (es) 2002-08-26
EP1341766A1 (de) 2003-09-10
MXPA03004454A (es) 2003-08-19
DE60114448T2 (de) 2006-07-06
PE20020636A1 (es) 2002-07-18
BR0115476A (pt) 2003-08-19
CA2428461A1 (en) 2002-05-30
AR035372A1 (es) 2004-05-12
ZA200303690B (en) 2004-08-13
KR100528760B1 (ko) 2005-11-15
UY27035A1 (es) 2002-06-20
WO2002042279A1 (en) 2002-05-30
ATE307805T1 (de) 2005-11-15
KR20030060951A (ko) 2003-07-16
AU2184202A (en) 2002-06-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee