ATE226980T1 - Transformant fähig zur herstellung von d- aminosäureoxidasen - Google Patents
Transformant fähig zur herstellung von d- aminosäureoxidasenInfo
- Publication number
- ATE226980T1 ATE226980T1 AT93202219T AT93202219T ATE226980T1 AT E226980 T1 ATE226980 T1 AT E226980T1 AT 93202219 T AT93202219 T AT 93202219T AT 93202219 T AT93202219 T AT 93202219T AT E226980 T1 ATE226980 T1 AT E226980T1
- Authority
- AT
- Austria
- Prior art keywords
- trigonopsis variabilis
- amino acid
- cephalosporin
- transformant
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
- C12N9/0024—D-Amino acid oxidase (1.4.3.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
- C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
- C12Y104/03003—D-Amino-acid oxidase (1.4.3.3)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP19994892 | 1992-07-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE226980T1 true ATE226980T1 (de) | 2002-11-15 |
Family
ID=16416266
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93202219T ATE226980T1 (de) | 1992-07-27 | 1993-07-27 | Transformant fähig zur herstellung von d- aminosäureoxidasen |
Country Status (8)
Country | Link |
---|---|
US (1) | US5453374A (de) |
EP (1) | EP0583817B1 (de) |
KR (1) | KR0131063B1 (de) |
CN (1) | CN1064079C (de) |
AT (1) | ATE226980T1 (de) |
CA (1) | CA2100987C (de) |
DE (1) | DE69332447T2 (de) |
ES (1) | ES2185620T3 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2097080B1 (es) * | 1993-03-08 | 1997-11-16 | Asahi Chemical Ind | Procedimiento para la conversion de cefalosporina c en acido glutaril-7-aminocefalosporanico. |
IT1275909B1 (it) * | 1995-03-07 | 1997-10-24 | Mirella Pilone | Frammento di dna codificante d-amminoacido ossidasi |
ES2109194B1 (es) | 1996-04-22 | 1998-07-16 | Antibioticos Sa | Un procedimiento para producir la enzima d-aminoacido oxidasa de rhodotorula gracilis en celulas hospedantes. |
WO1998059037A1 (en) * | 1997-06-25 | 1998-12-30 | Bristol-Myers Squibb Company | D-amino acid oxidase promoter from t. variabilis |
ES2131018B1 (es) | 1997-09-25 | 2000-04-01 | Antibioticos Sau | Un procedimiento enzimatico para preparar acido 7beta-(4-carboxibutanamido)cefalosporanico utilizando la enzima d-aminoacido oxidasa de trigonopsis variabilis modificada producida en escherichia coli. |
KR100246820B1 (ko) * | 1997-12-30 | 2000-03-15 | 정수련 | 신균주 트리고높시스 배리아빌리스에 의한 에리쓰리톨의 제조방법 |
KR20040014498A (ko) | 2001-04-19 | 2004-02-14 | 바이오퍼마 무르시아, 에스.에이. | 세팔로스포린 유도체의 제조 방법 |
CN100342014C (zh) | 2004-04-08 | 2007-10-10 | 百瑞全球有限公司 | 重组d-氨基酸氧化酶 |
CN1932013B (zh) * | 2005-09-13 | 2011-07-27 | 三得利控股株式会社 | 酯酶基因及其用途 |
CN102505035B (zh) * | 2011-10-25 | 2014-07-09 | 石药集团中诺药业(石家庄)有限公司 | 一种3-去乙酰基-7-氨基头孢烷酸的制备工艺 |
CN103710361B (zh) * | 2013-07-12 | 2015-07-15 | 广西大学 | 一种编码D-氨基酸氧化酶的基因daoE及其应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1385685A (en) * | 1971-04-21 | 1975-02-26 | Glaxo Lab Ltd | Cephalosporin derivatives |
JPS5535118A (en) * | 1978-08-31 | 1980-03-12 | Matsushita Electric Works Ltd | Driving shaft fixing apparatus of diaphragm pump |
JPS62262994A (ja) * | 1986-05-12 | 1987-11-16 | Asahi Chem Ind Co Ltd | D−アミノ酸オキシダ−ゼ遺伝子 |
JPH07108225B2 (ja) * | 1986-09-16 | 1995-11-22 | 旭化成工業株式会社 | D−アミノ酸オキシダ−ゼ遺伝子 |
JP2876652B2 (ja) * | 1988-10-13 | 1999-03-31 | 藤沢薬品工業株式会社 | D―アミノ酸オキシダーゼ |
ES2075056T3 (es) * | 1988-10-13 | 1995-10-01 | Fujisawa Pharmaceutical Co | Oxidasa de los d-aminoacidos. |
CA2049958A1 (en) * | 1989-04-04 | 1990-10-05 | Bing L. Wong | Enzymatic production of 7-amino cephalosporanic acid |
CA2021299C (en) * | 1989-07-19 | 1999-08-17 | Jeffrey T. Vicenzi | Enzymatic oxidation of ceph c to glutaryl-7-amino cephalosporanic acid |
KR0171897B1 (ko) * | 1989-12-27 | 1999-02-01 | 후지사와 도모끼찌로 | 7-아미노세펨 화합물 또는 그 염류의 제조 방법 |
DE4028119C1 (de) * | 1990-09-05 | 1991-12-05 | Hoechst Ag, 6230 Frankfurt, De |
-
1993
- 1993-07-21 CA CA002100987A patent/CA2100987C/en not_active Expired - Lifetime
- 1993-07-23 US US08/096,741 patent/US5453374A/en not_active Expired - Lifetime
- 1993-07-26 KR KR1019930014228A patent/KR0131063B1/ko not_active IP Right Cessation
- 1993-07-27 EP EP93202219A patent/EP0583817B1/de not_active Expired - Lifetime
- 1993-07-27 ES ES93202219T patent/ES2185620T3/es not_active Expired - Lifetime
- 1993-07-27 DE DE69332447T patent/DE69332447T2/de not_active Expired - Lifetime
- 1993-07-27 CN CN93116851A patent/CN1064079C/zh not_active Expired - Lifetime
- 1993-07-27 AT AT93202219T patent/ATE226980T1/de active
Also Published As
Publication number | Publication date |
---|---|
KR0131063B1 (ko) | 1998-04-11 |
CA2100987C (en) | 1999-06-15 |
EP0583817A3 (de) | 1995-01-11 |
US5453374A (en) | 1995-09-26 |
CN1064079C (zh) | 2001-04-04 |
ES2185620T3 (es) | 2003-05-01 |
CA2100987A1 (en) | 1994-01-28 |
KR940002352A (ko) | 1994-02-17 |
CN1087118A (zh) | 1994-05-25 |
DE69332447T2 (de) | 2003-07-03 |
EP0583817B1 (de) | 2002-10-30 |
EP0583817A2 (de) | 1994-02-23 |
DE69332447D1 (de) | 2002-12-05 |
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