ATE129012T1 - Enzymatische oxidation von ceph c zu glutaryl-7- aminocephalosporansäure. - Google Patents
Enzymatische oxidation von ceph c zu glutaryl-7- aminocephalosporansäure.Info
- Publication number
- ATE129012T1 ATE129012T1 AT90307738T AT90307738T ATE129012T1 AT E129012 T1 ATE129012 T1 AT E129012T1 AT 90307738 T AT90307738 T AT 90307738T AT 90307738 T AT90307738 T AT 90307738T AT E129012 T1 ATE129012 T1 AT E129012T1
- Authority
- AT
- Austria
- Prior art keywords
- glutaryl
- aminoocephalosporanic
- ceph
- acid
- enzymatic oxidation
- Prior art date
Links
- 230000002255 enzymatic effect Effects 0.000 title abstract 2
- 230000003647 oxidation Effects 0.000 title abstract 2
- 238000007254 oxidation reaction Methods 0.000 title abstract 2
- WGZDBVOTUVNQFP-UHFFFAOYSA-N N-(1-phthalazinylamino)carbamic acid ethyl ester Chemical compound C1=CC=C2C(NNC(=O)OCC)=NN=CC2=C1 WGZDBVOTUVNQFP-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- IXUSDMGLUJZNFO-BXUZGUMPSA-N (7R)-7-(4-carboxybutanamido)cephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCCC(O)=O)[C@@H]12 IXUSDMGLUJZNFO-BXUZGUMPSA-N 0.000 abstract 1
- 108090000371 Esterases Proteins 0.000 abstract 1
- 230000009849 deactivation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
- C12N9/0024—D-Amino acid oxidase (1.4.3.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/99—Enzyme inactivation by chemical treatment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cephalosporin Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38250589A | 1989-07-19 | 1989-07-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE129012T1 true ATE129012T1 (de) | 1995-10-15 |
Family
ID=23509253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90307738T ATE129012T1 (de) | 1989-07-19 | 1990-07-16 | Enzymatische oxidation von ceph c zu glutaryl-7- aminocephalosporansäure. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5424203A (de) |
| EP (2) | EP0601996A1 (de) |
| JP (1) | JP2883173B2 (de) |
| KR (1) | KR0163175B1 (de) |
| AT (1) | ATE129012T1 (de) |
| CA (2) | CA2268710C (de) |
| DE (1) | DE69022909T2 (de) |
| DK (1) | DK0409521T3 (de) |
| ES (1) | ES2079442T3 (de) |
| GR (1) | GR3017731T3 (de) |
| HU (1) | HU212587B (de) |
| IE (1) | IE71523B1 (de) |
| IL (1) | IL95090A (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0409521T3 (da) * | 1989-07-19 | 1996-02-05 | Lilly Co Eli | Forbedret enzymatisk oxidation af Ceph C til glutaryl-7-aminocephalosporansyre |
| DE4028119C1 (de) * | 1990-09-05 | 1991-12-05 | Hoechst Ag, 6230 Frankfurt, De | |
| CA2100987C (en) * | 1992-07-27 | 1999-06-15 | Kaoru Furuya | A transformant capable of producing d-amino acid oxidase |
| EP0600247A3 (de) * | 1992-11-05 | 1995-05-10 | Hoechst Ag | Verfahren zur selektiven Desaktivierung von unerwünschten Proteinen in einem Proteingemisch mittels Mikrowelleneinstrahlung. |
| ES2097080B1 (es) * | 1993-03-08 | 1997-11-16 | Asahi Chemical Ind | Procedimiento para la conversion de cefalosporina c en acido glutaril-7-aminocefalosporanico. |
| CN1203627A (zh) * | 1995-12-07 | 1998-12-30 | 诺沃挪第克公司 | 酶活性的选择性灭活 |
| EP0991752A2 (de) * | 1997-09-09 | 2000-04-12 | Biochemie Gesellschaft M.B.H. | Esterase freie enzymen |
| AU2002227889A1 (en) * | 2001-01-31 | 2002-08-12 | Novozymes A/S | Oxidase free of catalase side activities |
| KR100512774B1 (ko) * | 2001-10-06 | 2005-09-07 | 종근당바이오 주식회사 | 7-아미노세팔로스포란산의 제조를 위한 세팔로스포린ｃ배양액의 전처리방법 |
| US20090208543A1 (en) * | 2008-01-22 | 2009-08-20 | Oral Health Clinical Services | Method and apparatus for applying a protective oral care composition |
| WO2017221944A1 (ja) | 2016-06-21 | 2017-12-28 | パナソニックヘルスケアホールディングス株式会社 | カタラーゼ阻害剤及びカタラーゼ阻害剤を用いるアナライトの測定方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1272769A (en) * | 1968-08-02 | 1972-05-03 | Glaxo Lab Ltd | Improvements in or relating to cephalosporin derivatives |
| GB1385685A (en) * | 1971-04-21 | 1975-02-26 | Glaxo Lab Ltd | Cephalosporin derivatives |
| GB1474519A (de) * | 1973-05-14 | 1977-05-25 | ||
| US3976546A (en) * | 1974-11-08 | 1976-08-24 | Glaxo Laboratories Limited | Cephalosporins |
| US4079180A (en) * | 1975-01-22 | 1978-03-14 | Asahi Kasei Kogyo Kabushiki Kaisha | Process for preparing 7-aminocephalosporanic acid derivatives |
| US4394450A (en) * | 1982-03-01 | 1983-07-19 | Miles Laboratories, Inc. | Method for purification of uricase |
| DE3447023A1 (de) * | 1984-12-22 | 1986-06-26 | Hoechst Ag, 6230 Frankfurt | Neue d-aminosaeure-transaminase und ihre verwendung |
| DK0409521T3 (da) * | 1989-07-19 | 1996-02-05 | Lilly Co Eli | Forbedret enzymatisk oxidation af Ceph C til glutaryl-7-aminocephalosporansyre |
-
1990
- 1990-07-16 DK DK90307738.6T patent/DK0409521T3/da active
- 1990-07-16 EP EP94100223A patent/EP0601996A1/de not_active Withdrawn
- 1990-07-16 CA CA002268710A patent/CA2268710C/en not_active Expired - Fee Related
- 1990-07-16 IL IL9509090A patent/IL95090A/en not_active IP Right Cessation
- 1990-07-16 EP EP90307738A patent/EP0409521B1/de not_active Expired - Lifetime
- 1990-07-16 ES ES90307738T patent/ES2079442T3/es not_active Expired - Lifetime
- 1990-07-16 DE DE69022909T patent/DE69022909T2/de not_active Expired - Fee Related
- 1990-07-16 CA CA002021299A patent/CA2021299C/en not_active Expired - Fee Related
- 1990-07-16 AT AT90307738T patent/ATE129012T1/de not_active IP Right Cessation
- 1990-07-18 JP JP2192858A patent/JP2883173B2/ja not_active Expired - Lifetime
- 1990-07-18 HU HU904539A patent/HU212587B/hu not_active IP Right Cessation
- 1990-07-18 IE IE262390A patent/IE71523B1/en not_active IP Right Cessation
- 1990-07-18 KR KR1019900010913A patent/KR0163175B1/ko not_active Expired - Fee Related
-
1994
- 1994-03-11 US US08/212,656 patent/US5424203A/en not_active Expired - Fee Related
-
1995
- 1995-02-22 US US08/392,438 patent/US5559006A/en not_active Expired - Fee Related
- 1995-10-12 GR GR950402684T patent/GR3017731T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5424203A (en) | 1995-06-13 |
| EP0601996A1 (de) | 1994-06-15 |
| IL95090A (en) | 1995-08-31 |
| CA2021299C (en) | 1999-08-17 |
| HUT59727A (en) | 1992-06-29 |
| EP0409521A3 (en) | 1991-09-11 |
| EP0409521B1 (de) | 1995-10-11 |
| EP0409521A2 (de) | 1991-01-23 |
| DK0409521T3 (da) | 1996-02-05 |
| IE902623A1 (en) | 1991-02-27 |
| US5559006A (en) | 1996-09-24 |
| KR0163175B1 (ko) | 1998-11-16 |
| JPH0353879A (ja) | 1991-03-07 |
| DE69022909T2 (de) | 1996-04-11 |
| ES2079442T3 (es) | 1996-01-16 |
| CA2268710C (en) | 2000-09-26 |
| GR3017731T3 (en) | 1996-01-31 |
| IL95090A0 (en) | 1991-06-10 |
| HU212587B (en) | 1996-08-29 |
| JP2883173B2 (ja) | 1999-04-19 |
| KR910003114A (ko) | 1991-02-26 |
| HU904539D0 (en) | 1990-12-28 |
| CA2021299A1 (en) | 1991-01-20 |
| DE69022909D1 (de) | 1995-11-16 |
| IE71523B1 (en) | 1997-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |