DE69022909D1 - Enzymatische Oxidation von Ceph C zu Glutaryl-7-Aminocephalosporansäure. - Google Patents

Enzymatische Oxidation von Ceph C zu Glutaryl-7-Aminocephalosporansäure.

Info

Publication number
DE69022909D1
DE69022909D1 DE69022909T DE69022909T DE69022909D1 DE 69022909 D1 DE69022909 D1 DE 69022909D1 DE 69022909 T DE69022909 T DE 69022909T DE 69022909 T DE69022909 T DE 69022909T DE 69022909 D1 DE69022909 D1 DE 69022909D1
Authority
DE
Germany
Prior art keywords
glutaryl
ceph
enzymatic oxidation
aminocephalosporanic acid
oxidation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69022909T
Other languages
English (en)
Other versions
DE69022909T2 (de
Inventor
Jeffrey Thomas Vicenzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE69022909D1 publication Critical patent/DE69022909D1/de
Publication of DE69022909T2 publication Critical patent/DE69022909T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12N9/0024—D-Amino acid oxidase (1.4.3.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99—Enzyme inactivation by chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DE69022909T 1989-07-19 1990-07-16 Enzymatische Oxidation von Ceph C zu Glutaryl-7-Aminocephalosporansäure. Expired - Fee Related DE69022909T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38250589A 1989-07-19 1989-07-19

Publications (2)

Publication Number Publication Date
DE69022909D1 true DE69022909D1 (de) 1995-11-16
DE69022909T2 DE69022909T2 (de) 1996-04-11

Family

ID=23509253

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69022909T Expired - Fee Related DE69022909T2 (de) 1989-07-19 1990-07-16 Enzymatische Oxidation von Ceph C zu Glutaryl-7-Aminocephalosporansäure.

Country Status (13)

Country Link
US (2) US5424203A (de)
EP (2) EP0409521B1 (de)
JP (1) JP2883173B2 (de)
KR (1) KR0163175B1 (de)
AT (1) ATE129012T1 (de)
CA (2) CA2021299C (de)
DE (1) DE69022909T2 (de)
DK (1) DK0409521T3 (de)
ES (1) ES2079442T3 (de)
GR (1) GR3017731T3 (de)
HU (1) HU212587B (de)
IE (1) IE71523B1 (de)
IL (1) IL95090A (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2021299C (en) * 1989-07-19 1999-08-17 Jeffrey T. Vicenzi Enzymatic oxidation of ceph c to glutaryl-7-amino cephalosporanic acid
DE4028119C1 (de) * 1990-09-05 1991-12-05 Hoechst Ag, 6230 Frankfurt, De
CA2100987C (en) * 1992-07-27 1999-06-15 Kaoru Furuya A transformant capable of producing d-amino acid oxidase
EP0600247A3 (de) * 1992-11-05 1995-05-10 Hoechst Ag Verfahren zur selektiven Desaktivierung von unerwünschten Proteinen in einem Proteingemisch mittels Mikrowelleneinstrahlung.
GB2275925B (en) * 1993-03-08 1996-08-14 Asahi Chemical Ind A process for converting cephalosporin C to glutaryl-7-aminocephalosporanic acid
CN1203627A (zh) * 1995-12-07 1998-12-30 诺沃挪第克公司 酶活性的选择性灭活
US6465227B1 (en) 1997-09-09 2002-10-15 Biochemie Gesellschaft M.B.H. Spherical particles containing microorganism cells having enzyme activity
WO2002061068A2 (en) * 2001-01-31 2002-08-08 Novozymes A/S Oxidase free of catalase side activities
KR100512774B1 (ko) * 2001-10-06 2005-09-07 종근당바이오 주식회사 7-아미노세팔로스포란산의 제조를 위한 세팔로스포린ｃ배양액의 전처리방법
US20090208543A1 (en) * 2008-01-22 2009-08-20 Oral Health Clinical Services Method and apparatus for applying a protective oral care composition
WO2017221944A1 (ja) * 2016-06-21 2017-12-28 パナソニックヘルスケアホールディングス株式会社 カタラーゼ阻害剤及びカタラーゼ阻害剤を用いるアナライトの測定方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1272769A (en) * 1968-08-02 1972-05-03 Glaxo Lab Ltd Improvements in or relating to cephalosporin derivatives
GB1385685A (en) * 1971-04-21 1975-02-26 Glaxo Lab Ltd Cephalosporin derivatives
GB1474519A (de) * 1973-05-14 1977-05-25
US3976546A (en) * 1974-11-08 1976-08-24 Glaxo Laboratories Limited Cephalosporins
US4079180A (en) * 1975-01-22 1978-03-14 Asahi Kasei Kogyo Kabushiki Kaisha Process for preparing 7-aminocephalosporanic acid derivatives
US4394450A (en) * 1982-03-01 1983-07-19 Miles Laboratories, Inc. Method for purification of uricase
DE3447023A1 (de) * 1984-12-22 1986-06-26 Hoechst Ag, 6230 Frankfurt Neue d-aminosaeure-transaminase und ihre verwendung
CA2021299C (en) * 1989-07-19 1999-08-17 Jeffrey T. Vicenzi Enzymatic oxidation of ceph c to glutaryl-7-amino cephalosporanic acid

Also Published As

Publication number Publication date
JP2883173B2 (ja) 1999-04-19
ES2079442T3 (es) 1996-01-16
CA2268710C (en) 2000-09-26
HUT59727A (en) 1992-06-29
IL95090A (en) 1995-08-31
EP0409521A3 (en) 1991-09-11
CA2021299C (en) 1999-08-17
HU212587B (en) 1996-08-29
CA2021299A1 (en) 1991-01-20
EP0409521B1 (de) 1995-10-11
US5559006A (en) 1996-09-24
IE902623A1 (en) 1991-02-27
DE69022909T2 (de) 1996-04-11
IL95090A0 (en) 1991-06-10
KR910003114A (ko) 1991-02-26
EP0409521A2 (de) 1991-01-23
US5424203A (en) 1995-06-13
EP0601996A1 (de) 1994-06-15
KR0163175B1 (ko) 1998-11-16
HU904539D0 (en) 1990-12-28
IE71523B1 (en) 1997-02-12
DK0409521T3 (da) 1996-02-05
ATE129012T1 (de) 1995-10-15
JPH0353879A (ja) 1991-03-07
GR3017731T3 (en) 1996-01-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee