ATE154039T1 - Verfahren zur synthese von halbsynthetischen glykosaminoglykanen mit heparin- oder heparanstruktur, die in 2-position modifiziertes alpha-l-iduronsäure-2-o-sulfat enthalten - Google Patents
Verfahren zur synthese von halbsynthetischen glykosaminoglykanen mit heparin- oder heparanstruktur, die in 2-position modifiziertes alpha-l-iduronsäure-2-o-sulfat enthaltenInfo
- Publication number
- ATE154039T1 ATE154039T1 AT94104306T AT94104306T ATE154039T1 AT E154039 T1 ATE154039 T1 AT E154039T1 AT 94104306 T AT94104306 T AT 94104306T AT 94104306 T AT94104306 T AT 94104306T AT E154039 T1 ATE154039 T1 AT E154039T1
- Authority
- AT
- Austria
- Prior art keywords
- heparin
- sulfate
- synthesis
- semi
- heparatic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93BO000125A IT1264101B1 (it) | 1993-03-29 | 1993-03-29 | Processo per la sintesi di glicosaminoglicani semisintetici a struttura eparinica od eparanica modificati nella posizione 2 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE154039T1 true ATE154039T1 (de) | 1997-06-15 |
Family
ID=11338858
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94104306T ATE154039T1 (de) | 1993-03-29 | 1994-03-18 | Verfahren zur synthese von halbsynthetischen glykosaminoglykanen mit heparin- oder heparanstruktur, die in 2-position modifiziertes alpha-l-iduronsäure-2-o-sulfat enthalten |
Country Status (18)
Country | Link |
---|---|
US (1) | US5405949A (de) |
EP (1) | EP0618234B1 (de) |
JP (1) | JP2731721B2 (de) |
KR (1) | KR100194122B1 (de) |
AT (1) | ATE154039T1 (de) |
AU (1) | AU664939B2 (de) |
CA (1) | CA2114862C (de) |
DE (1) | DE69403537T2 (de) |
DK (1) | DK0618234T3 (de) |
ES (1) | ES2102087T3 (de) |
FI (1) | FI105101B (de) |
GR (1) | GR3024416T3 (de) |
IL (1) | IL108689A (de) |
IT (1) | IT1264101B1 (de) |
NO (1) | NO305994B1 (de) |
NZ (1) | NZ250815A (de) |
TW (1) | TW266215B (de) |
ZA (1) | ZA94970B (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6255295B1 (en) | 1996-12-23 | 2001-07-03 | Nutramax Laboratories, Inc. | Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue |
US7259152B2 (en) | 2000-06-07 | 2007-08-21 | Alfa Wasserman, Inc. | Methods and compositions using sulodexide for the treatment of diabetic nephropathy |
CA2435637A1 (en) | 2001-01-23 | 2002-08-01 | Massachusetts Institute Of Technology | Solid- and solution -phase synthesis of heparin and other glycosaminoglycans |
EP2343077B1 (de) | 2001-09-12 | 2013-07-17 | SIGMA-TAU Research Switzerland S.A. | Derivate von total N-desulfatierten Glycosaminoglycanen als Inhibitoren von Heparanase, mit antiangiogener Wirkung und ohne antikoagulatorische Wirkung |
GB0216861D0 (en) * | 2002-07-19 | 2002-08-28 | Univ Birmingham | Saccharide libraries |
JP7401882B2 (ja) * | 2016-03-09 | 2023-12-20 | 株式会社糖鎖工学研究所 | 硫酸基を有する糖の製造方法 |
WO2021128253A1 (zh) * | 2019-12-27 | 2021-07-01 | 深圳市海普瑞药业集团股份有限公司 | 一种糖胺聚糖衍生物及其应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4987223A (en) * | 1981-12-23 | 1991-01-22 | Choay S.A. | Derivatives of the uronic acid |
US6174999B1 (en) * | 1987-09-18 | 2001-01-16 | Genzyme Corporation | Water insoluble derivatives of polyanionic polysaccharides |
IT1234508B (it) * | 1988-06-10 | 1992-05-19 | Alfa Wassermann Spa | Derivati eparinici e procedimento per la loro preparazione |
US5011919A (en) * | 1989-01-30 | 1991-04-30 | Ajorca S.A. | Modified heparins and obtention process |
IT1234826B (it) * | 1989-01-30 | 1992-05-29 | Alfa Wassermann Spa | Derivati eparinici e procedimento per la loro preparazione |
IT1242604B (it) * | 1990-11-13 | 1994-05-16 | Alfa Wassermann Spa | Sali di glicosaminoglicani con esteri di aminoacidi, loro preparazione e formulazioni farmaceutiche che li contengono. |
IT1260136B (it) * | 1992-04-17 | 1996-03-28 | Alfa Wassermann Spa | Glicosaminoglicani semisintetici contenenti acido alfa-l-galatturonicosostituito con radicali nucleofili in posizione 3 |
IT1260137B (it) * | 1992-04-17 | 1996-03-28 | Alfa Wassermann Spa | Glicosaminoglicani semisintetici a struttura eparinica od eparanica modificati nella posizione 2 dell'acido alfa-l-iduronico-2-0-solfato |
BE1006134A6 (fr) * | 1992-08-25 | 1994-05-24 | Syntex Sa | Procede de preparation de derives 2-desoxy-2-amino hexuronyles d'heparine, derives tels qu'ainsi obtenus et leur utilisation. |
-
1993
- 1993-03-29 IT IT93BO000125A patent/IT1264101B1/it active IP Right Grant
-
1994
- 1994-02-03 NZ NZ250815A patent/NZ250815A/en unknown
- 1994-02-03 CA CA002114862A patent/CA2114862C/en not_active Expired - Fee Related
- 1994-02-10 AU AU55085/94A patent/AU664939B2/en not_active Ceased
- 1994-02-11 ZA ZA94970A patent/ZA94970B/xx unknown
- 1994-02-17 IL IL108689A patent/IL108689A/en not_active IP Right Cessation
- 1994-02-18 TW TW083101327A patent/TW266215B/zh active
- 1994-03-07 US US08/206,980 patent/US5405949A/en not_active Expired - Lifetime
- 1994-03-18 EP EP94104306A patent/EP0618234B1/de not_active Expired - Lifetime
- 1994-03-18 AT AT94104306T patent/ATE154039T1/de not_active IP Right Cessation
- 1994-03-18 DE DE69403537T patent/DE69403537T2/de not_active Expired - Fee Related
- 1994-03-18 ES ES94104306T patent/ES2102087T3/es not_active Expired - Lifetime
- 1994-03-18 DK DK94104306.9T patent/DK0618234T3/da active
- 1994-03-25 KR KR1019940006018A patent/KR100194122B1/ko not_active IP Right Cessation
- 1994-03-28 FI FI941431A patent/FI105101B/fi not_active IP Right Cessation
- 1994-03-28 NO NO941128A patent/NO305994B1/no not_active IP Right Cessation
- 1994-03-29 JP JP6059447A patent/JP2731721B2/ja not_active Expired - Fee Related
-
1997
- 1997-08-13 GR GR970402059T patent/GR3024416T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
TW266215B (de) | 1995-12-21 |
EP0618234A1 (de) | 1994-10-05 |
KR940021582A (ko) | 1994-10-19 |
ITBO930125A1 (it) | 1994-09-29 |
GR3024416T3 (en) | 1997-11-28 |
FI105101B (fi) | 2000-06-15 |
NO941128L (no) | 1994-09-30 |
KR100194122B1 (ko) | 1999-06-15 |
IL108689A0 (en) | 1994-05-30 |
FI941431A0 (fi) | 1994-03-28 |
FI941431A (fi) | 1994-09-30 |
IT1264101B1 (it) | 1996-09-10 |
ITBO930125A0 (it) | 1993-03-29 |
DK0618234T3 (da) | 1997-08-25 |
NO941128D0 (no) | 1994-03-28 |
CA2114862A1 (en) | 1994-09-30 |
DE69403537T2 (de) | 1997-09-18 |
JP2731721B2 (ja) | 1998-03-25 |
DE69403537D1 (de) | 1997-07-10 |
IL108689A (en) | 1998-03-10 |
JPH06298805A (ja) | 1994-10-25 |
US5405949A (en) | 1995-04-11 |
AU664939B2 (en) | 1995-12-07 |
AU5508594A (en) | 1994-10-06 |
ZA94970B (en) | 1994-08-24 |
ES2102087T3 (es) | 1997-07-16 |
CA2114862C (en) | 1999-05-25 |
NZ250815A (en) | 1996-02-27 |
EP0618234B1 (de) | 1997-06-04 |
NO305994B1 (no) | 1999-08-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |