IT1242604B - Sali di glicosaminoglicani con esteri di aminoacidi, loro preparazione e formulazioni farmaceutiche che li contengono. - Google Patents

Sali di glicosaminoglicani con esteri di aminoacidi, loro preparazione e formulazioni farmaceutiche che li contengono.

Info

Publication number
IT1242604B
IT1242604B IT00372890A IT372890A IT1242604B IT 1242604 B IT1242604 B IT 1242604B IT 00372890 A IT00372890 A IT 00372890A IT 372890 A IT372890 A IT 372890A IT 1242604 B IT1242604 B IT 1242604B
Authority
IT
Italy
Prior art keywords
glycosaminoglican
salts
contain
preparation
amino acid
Prior art date
Application number
IT00372890A
Other languages
English (en)
Other versions
IT9003728A1 (it
IT9003728A0 (it
Inventor
Manlio Cristofori
Egidio Marchi
Leone Gabriele Rotini
Original Assignee
Alfa Wassermann Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Wassermann Spa filed Critical Alfa Wassermann Spa
Priority to IT00372890A priority Critical patent/IT1242604B/it
Publication of IT9003728A0 publication Critical patent/IT9003728A0/it
Priority to DE69121058T priority patent/DE69121058T2/de
Priority to EP91117517A priority patent/EP0485748B1/en
Priority to ES91117517T priority patent/ES2090202T3/es
Priority to KR1019910020006A priority patent/KR0130965B1/ko
Priority to JP3295839A priority patent/JP2550452B2/ja
Publication of IT9003728A1 publication Critical patent/IT9003728A1/it
Application granted granted Critical
Publication of IT1242604B publication Critical patent/IT1242604B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
IT00372890A 1990-11-13 1990-11-13 Sali di glicosaminoglicani con esteri di aminoacidi, loro preparazione e formulazioni farmaceutiche che li contengono. IT1242604B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT00372890A IT1242604B (it) 1990-11-13 1990-11-13 Sali di glicosaminoglicani con esteri di aminoacidi, loro preparazione e formulazioni farmaceutiche che li contengono.
DE69121058T DE69121058T2 (de) 1990-11-13 1991-10-14 Salze von Glykosaminoglykanen mit Aminosäureester, ihre Herstellung sowie sie enthaltende pharmazeutische Zusammensetzungen
EP91117517A EP0485748B1 (en) 1990-11-13 1991-10-14 Salts of glycosaminoglycans with esters of aminoacids, preparation thereof and pharmaceutical formulations containing them
ES91117517T ES2090202T3 (es) 1990-11-13 1991-10-14 Sales de glucosaminoglicanos con esteres de aminoacidos, su preparacion y formulaciones farmaceuticas que las contienen.
KR1019910020006A KR0130965B1 (ko) 1990-11-13 1991-11-12 글리코스아미노글리칸과 아미노산의 에스테르의 염 및 그 제조방법과 이러한 염을 함유하는 제약조성물
JP3295839A JP2550452B2 (ja) 1990-11-13 1991-11-12 グリコサミノグリカンとアミノ酸エステルとの塩、その製造法およびそれを含有する経口投与用薬学的製剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT00372890A IT1242604B (it) 1990-11-13 1990-11-13 Sali di glicosaminoglicani con esteri di aminoacidi, loro preparazione e formulazioni farmaceutiche che li contengono.

Publications (3)

Publication Number Publication Date
IT9003728A0 IT9003728A0 (it) 1990-11-13
IT9003728A1 IT9003728A1 (it) 1992-05-13
IT1242604B true IT1242604B (it) 1994-05-16

Family

ID=11111557

Family Applications (1)

Application Number Title Priority Date Filing Date
IT00372890A IT1242604B (it) 1990-11-13 1990-11-13 Sali di glicosaminoglicani con esteri di aminoacidi, loro preparazione e formulazioni farmaceutiche che li contengono.

Country Status (6)

Country Link
EP (1) EP0485748B1 (it)
JP (1) JP2550452B2 (it)
KR (1) KR0130965B1 (it)
DE (1) DE69121058T2 (it)
ES (1) ES2090202T3 (it)
IT (1) IT1242604B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1264101B1 (it) * 1993-03-29 1996-09-10 Alfa Wassermann Spa Processo per la sintesi di glicosaminoglicani semisintetici a struttura eparinica od eparanica modificati nella posizione 2
IT1264102B1 (it) * 1993-03-29 1996-09-10 Alfa Wassermann Spa Processo per la sintesi di glicosaminoglicani semisintetici contenenti acido alfa-l-galatturonico sostituito con radicali
AUPO888497A0 (en) 1997-09-01 1997-09-25 Australian National University, The Use of sulfated oligosaccharides as inhibitors of cardiovascular disease
US7259152B2 (en) 2000-06-07 2007-08-21 Alfa Wasserman, Inc. Methods and compositions using sulodexide for the treatment of diabetic nephropathy
JP4915888B2 (ja) * 2001-08-01 2012-04-11 株式会社ジャパンエコロジーシンキング 豚皮抽出物よりのデルマタン硫酸の製造方法
RU2318521C1 (ru) * 2006-08-02 2008-03-10 Роман Владиславович Бочаров Способ проведения антикоагулянтной терапии у детей с термической травмой
IT1401253B1 (it) * 2010-04-23 2013-07-18 Uni Degli Studi Carlo Bo Urbino Uso del sulodexide per la riduzione delle metalloproteinasi di matrice.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3088868A (en) * 1958-08-18 1963-05-07 Riker Laboratories Inc Orally-active therapeutic compositions and process for using same
US3506642A (en) * 1967-07-03 1970-04-14 Canada Packers Ltd Stable orally active heparinoid complexes
HU172937B (hu) * 1975-12-18 1979-01-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija novykh proizvodnykh khondroitin-sernoj kisloty s mestno anestezirujuhhim ehffektom
JPH04500377A (ja) * 1988-06-03 1992-01-23 イタルファルマコ　エッセ　ピ　ア グリコサミノグリカン塩、その製造方法およびそれを含有する医薬組成物

Also Published As

Publication number Publication date
IT9003728A1 (it) 1992-05-13
JP2550452B2 (ja) 1996-11-06
EP0485748B1 (en) 1996-07-24
JPH06157606A (ja) 1994-06-07
DE69121058T2 (de) 1996-12-19
ES2090202T3 (es) 1996-10-16
KR920009852A (ko) 1992-06-25
EP0485748A2 (en) 1992-05-20
IT9003728A0 (it) 1990-11-13
DE69121058D1 (de) 1996-08-29
EP0485748A3 (en) 1993-01-07
KR0130965B1 (ko) 1998-04-16

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19961108