IT8748544A0 - Alfa-amminoacidi sostituiti,loro preparazione e composizioni farmaceutiche che li contengono - Google Patents

Alfa-amminoacidi sostituiti,loro preparazione e composizioni farmaceutiche che li contengono

Info

Publication number
IT8748544A0
IT8748544A0 IT8748544A IT4854487A IT8748544A0 IT 8748544 A0 IT8748544 A0 IT 8748544A0 IT 8748544 A IT8748544 A IT 8748544A IT 4854487 A IT4854487 A IT 4854487A IT 8748544 A0 IT8748544 A0 IT 8748544A0
Authority
IT
Italy
Prior art keywords
contain
preparation
amino acids
pharmaceutical compositions
substituted alpha
Prior art date
Application number
IT8748544A
Other languages
English (en)
Other versions
IT1212033B (it
Inventor
Herrling Paul Linus
Mueller Werner
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT8748544A0 publication Critical patent/IT8748544A0/it
Application granted granted Critical
Publication of IT1212033B publication Critical patent/IT1212033B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3882—Arylalkanephosphonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056—Esters of arylalkanephosphonic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT8748544A 1986-10-30 1987-10-28 Alfa-amminoacidi sostituiti,loro preparazione e composizioni farmaceutiche che li contengono IT1212033B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868625941A GB8625941D0 (en) 1986-10-30 1986-10-30 Substituted alpha-amino acids

Publications (2)

Publication Number Publication Date
IT8748544A0 true IT8748544A0 (it) 1987-10-28
IT1212033B IT1212033B (it) 1989-11-08

Family

ID=10606531

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8748544A IT1212033B (it) 1986-10-30 1987-10-28 Alfa-amminoacidi sostituiti,loro preparazione e composizioni farmaceutiche che li contengono

Country Status (27)

Country Link
US (1) US5162311A (it)
JP (2) JPH0641475B2 (it)
KR (1) KR950004960B1 (it)
AT (1) AT393384B (it)
AU (1) AU614726B2 (it)
BE (1) BE1002421A4 (it)
CA (1) CA1310331C (it)
CH (1) CH677794A5 (it)
CY (1) CY1703A (it)
DE (1) DE3736016C2 (it)
DK (1) DK565987A (it)
ES (1) ES2012521A6 (it)
FI (1) FI87222C (it)
FR (1) FR2606018B1 (it)
GB (2) GB8625941D0 (it)
GR (1) GR871659B (it)
HK (1) HK110393A (it)
HU (1) HU200465B (it)
IE (1) IE59310B1 (it)
IL (1) IL84302A (it)
IT (1) IT1212033B (it)
LU (1) LU87031A1 (it)
NL (1) NL8702485A (it)
NZ (1) NZ222333A (it)
PT (1) PT86018B (it)
SE (1) SE466311B (it)
ZA (1) ZA878176B (it)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395827A (en) * 1986-04-09 1995-03-07 Guilford Pharmaceuticals Inc. ω-[2-(phosphonoalkyl)phenyl]-2-aminoalkanoic acids as antagonists of excitatory amino acid receptors
US4918064A (en) * 1987-10-21 1990-04-17 G. D. Searle & Co. Phenyl glycines for use in reducing neurotoxic injury
US5175153A (en) * 1987-11-30 1992-12-29 Warner-Lambert Company Substituted alpha-amino acids having pharmaceutical activity
FR2634763B1 (fr) * 1988-08-01 1991-07-12 Inst Nat Sante Rech Med Amino-acides et peptides presentant un residu tyrosine modifiee, leur preparation et leur application comme medicaments
US5177240A (en) * 1988-10-21 1993-01-05 G. D. Searle & Co. O-phosphono(alkyl)-n-sulfonyl-phenyl-alanine derivatives useful as intermediates for preparation of phosphono-hydroisoquinolines
US4997821A (en) * 1988-10-21 1991-03-05 Cordi Alexis A Phosphono-hydroisoquinoline compounds useful in reducing neurotoxic injury
US5100654A (en) * 1989-04-07 1992-03-31 Yale University Phosphorylated derivatives of l-dopa and compositions and methods for increasing the melanin content in mammalian skin and hair
DE3940410A1 (de) * 1989-12-04 1991-06-06 Schering Ag Neue verwendung von nmda-rezeptor-antagonisten
US5238958A (en) * 1990-02-26 1993-08-24 Warner-Lambert Company Substituted α-amino acids having selected acidic moieties for use as excitatory amino acid antagonists in pharmaceuticals
US5086072A (en) * 1990-06-18 1992-02-04 The United States Of America As Represented By The Department Of Health And Human Services Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex
US5200546A (en) * 1991-09-30 1993-04-06 The United States Of America As Represented By The Department Of Health And Human Services Phosphonoalkyl phenylalanine compounds suitably protected for use in peptide synthesis
US5475129A (en) * 1991-09-30 1995-12-12 The United States Of America As Represented By The Department Of Health And Human Services Phosphonoalkyl phenylalanine compounds suitably protected for use in peptide synthesis
US5264607A (en) * 1991-09-30 1993-11-23 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Process of making benzylic α,α-diflurophosphonates from benzylic α-ketophosphorates
GB9325360D0 (en) * 1993-12-10 1994-02-16 Univ Bristol Organic compounds
US5489717A (en) * 1994-07-08 1996-02-06 Warner-Lambert Company Glutamate (NMDA) receptor antagonists
GB9423019D0 (en) * 1994-11-15 1995-01-04 Sandoz Ltd Improvements in or relating to organic compounds
US5922697A (en) * 1996-10-02 1999-07-13 Warner-Lambert Company Compounds, compositions and methods for inhibiting the binding of proteins containing an SH2 domain to cognate phosphorylated proteins
US6133281A (en) * 1996-10-24 2000-10-17 Harbor-Ucla Research And Education Institute NMDA receptor blockers in the therapy of urogenital disease
ATE510542T1 (de) * 1997-09-04 2011-06-15 Novoneuron Inc Noribogain zur behandlung von schmerzen und drogenabhängigkeit
MY153569A (en) * 1998-01-20 2015-02-27 Mitsubishi Tanabe Pharma Corp Inhibitors of ?4 mediated cell adhesion
SE9804064D0 (sv) 1998-11-25 1998-11-25 A & Science Invest Ab Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells
MY140707A (en) * 2002-02-28 2010-01-15 Mitsubishi Tanabe Pharma Corp Process for preparing a phenylalanine derivative and intermediates thereof
DE10328260A1 (de) * 2003-06-23 2005-01-27 Schmidt, K.-G., Dr. med. Flupirtine-Präparat
EP1754483A1 (en) * 2005-08-18 2007-02-21 Merck Sante Use of thienopyridone derivatives as AMPK activators and pharmaceutical compositions containing them
JP2013534914A (ja) 2010-06-09 2013-09-09 クイーン マリー アンド ウエストフィールド カレッジ、ユニバーシティ オブ ロンドン アネキシン１抗体
GB201121564D0 (en) * 2011-12-14 2012-01-25 Queen Mary & Westfield College Use of antibody
GB201702091D0 (en) 2017-02-08 2017-03-22 Medannex Ltd Specific binding molecules
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL95975C (it) * 1955-08-30
BE626546A (it) * 1961-12-30
DE2459491A1 (de) * 1974-12-17 1976-06-24 Bayer Ag Gegenueber isocyanaten reaktive phosphorhaltige flammschutzmittel
US4657899A (en) * 1986-04-09 1987-04-14 Nova Pharmaceutical Corporation Antagonists of specific excitatory amino acid neurotransmitter receptors
US4761405A (en) * 1987-03-04 1988-08-02 Nova Pharmaceutical Corporation Antagonists of specific excitatory amino acid neurotransmitter receptors having increased potency
US4918064A (en) * 1987-10-21 1990-04-17 G. D. Searle & Co. Phenyl glycines for use in reducing neurotoxic injury

Also Published As

Publication number Publication date
DE3736016C2 (de) 1995-04-20
FI87222C (fi) 1992-12-10
CH677794A5 (it) 1991-06-28
IE872908L (en) 1988-04-30
AU614726B2 (en) 1991-09-12
GB2198134A (en) 1988-06-08
CA1310331C (en) 1992-11-17
IL84302A (en) 1993-06-10
CY1703A (en) 1994-01-14
FI874761A0 (fi) 1987-10-29
GB2198134B (en) 1990-07-04
NZ222333A (en) 1990-09-26
IE59310B1 (en) 1994-02-09
FR2606018B1 (fr) 1990-11-16
ES2012521A6 (es) 1990-04-01
FI874761A (fi) 1988-05-01
IL84302A0 (en) 1988-03-31
PT86018A (en) 1987-11-01
DE3736016A1 (de) 1988-05-05
BE1002421A4 (fr) 1991-02-05
AU8040487A (en) 1988-05-05
JPS63122693A (ja) 1988-05-26
ZA878176B (en) 1989-06-28
US5162311A (en) 1992-11-10
AT393384B (de) 1991-10-10
JPH03101685A (ja) 1991-04-26
KR950004960B1 (ko) 1995-05-16
GB8724186D0 (en) 1987-11-18
HK110393A (en) 1993-10-29
GB8625941D0 (en) 1986-12-03
DK565987A (da) 1988-05-01
NL8702485A (nl) 1988-05-16
GR871659B (en) 1988-03-03
SE8704204D0 (sv) 1987-10-28
KR890006661A (ko) 1989-06-15
HUT47949A (en) 1989-04-28
SE466311B (sv) 1992-01-27
HU200465B (en) 1990-06-28
IT1212033B (it) 1989-11-08
LU87031A1 (fr) 1988-05-03
JPH0641475B2 (ja) 1994-06-01
DK565987D0 (da) 1987-10-28
SE8704204L (sv) 1988-05-01
ATA285187A (de) 1991-03-15
PT86018B (pt) 1990-07-31
FR2606018A1 (fr) 1988-05-06
FI87222B (fi) 1992-08-31

Similar Documents

Publication Publication Date Title
IT8748544A0 (it) Alfa-amminoacidi sostituiti,loro preparazione e composizioni farmaceutiche che li contengono
IT8547877A0 (it) Alfa-amminoacidi,la loro preparazione e lecoomposizioni farmaceutihe che li contengono
IT8719165A0 (it) Derivato di acido tiazolidin-4-carbossilico, sua preparazione e composizioni farmaceutiche che lo contengono.
IT1226586B (it) Composizioni farmaceutiche che favoriscono la cicatrizzazione di ferite e procedimento per prepararle
IT1199860B (it) Polieteri glicosilati,composizioni che li comprendono,procedimento per la loro preparazione e impiego
IT1191050B (it) 2(1-alchil-5-nitro)-imidazolil-1-(2-idrossi-5-alchil)-fenil-carbinoli,loro metodo di preparazione e composizioni farmaceutiche che li contengono
IT8548964A0 (it) 8alfa-acilamminoergoline,loro preparazione e composizioni farmaceutiche che le contengono
IT8448800A0 (it) Amminociclopentani, composizioni farmaceutiche che li contengono eprocedimento per la loro preparazione
IT8419167A0 (it) Carbostirilossiminopropanolamine utili come medicamenti eprocedimento per la loro preparazione.
IT1185525B (it) Derivait di amminodiarilsolfossidi,procedimento per la loro preparazione e composizioni farmaceutiche e pesticide che li contengono
IT8547704A0 (it) Diazepinoindoli,loro preparazione e loro impiego come medicamenti
IT1172127B (it) Tioacil - carnitine procedimento per la loro preparazione e composizioni farmaceutiche che le contengono ad azione mucclitica
IT8348067A0 (it) Cianoguanidine, procedimento per ottenerle e composizioni farmaceutiche che le contengono
IT8747852A0 (it) Benzammidi sostituite, procedimento per la loro preparazione e composizioni farmaceutiche che le contengono
IT8348518A0 (it) Piperidinoguanidine sostituite,procedimento per la loro preparazione e composizioni farmaceutiche che le contengono
IT8647615A0 (it) Composizioni farmaceutiche comprendenti 3-amminopropossi-indoli
IT8320844A0 (it) Nuove argille modificate, loro preparazione e composizioni terapeutiche che le contengono
IT8823183A0 (it) Derivati diossazocinici, loro preparazione e composizioni che li contengono
IT1200472B (it) Derivati chinolinici,loro preparazione e composizioni terapeutiche che li contengono
IT1217192B (it) Tioeteri chinolinici,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT8619751A0 (it) Composizioni farmaceutiche contenenti vinburnina e loro procedimento di preparazione.
IT1204380B (it) Composti tiofensolfonamidici,composizioni erbicide che li contengono e procedimento per la loro preparazione
IT8348099A0 (it) Indolalchilenommine sostituite,loro preparazione e loro impiego come medicamenti
IT8249254A0 (it) 3-alchil, 4-carbossi butirrilcarnitine, procedimento per la loro preparazione e composizioni farmaceutiche che le contengono
IT8820468A0 (it) Piridobenzodiazepinoni, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19961024