ATE153342T1 - Adenosinderivate, verfahren zu deren herstellung und pharmazeutische mittel - Google Patents

Adenosinderivate, verfahren zu deren herstellung und pharmazeutische mittel

Info

Publication number
ATE153342T1
ATE153342T1 AT93914481T AT93914481T ATE153342T1 AT E153342 T1 ATE153342 T1 AT E153342T1 AT 93914481 T AT93914481 T AT 93914481T AT 93914481 T AT93914481 T AT 93914481T AT E153342 T1 ATE153342 T1 AT E153342T1
Authority
AT
Austria
Prior art keywords
production
pct
pharmaceutical agents
adenosine derivatives
sec
Prior art date
Application number
AT93914481T
Other languages
English (en)
Inventor
Nicole Bru-Magniez
Timur Gungor
Jean-Marie Teulon
Original Assignee
Union Pharma Scient Appl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Union Pharma Scient Appl filed Critical Union Pharma Scient Appl
Application granted granted Critical
Publication of ATE153342T1 publication Critical patent/ATE153342T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
AT93914481T 1992-01-08 1992-12-29 Adenosinderivate, verfahren zu deren herstellung und pharmazeutische mittel ATE153342T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9200138A FR2685918B1 (fr) 1992-01-08 1992-01-08 Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.

Publications (1)

Publication Number Publication Date
ATE153342T1 true ATE153342T1 (de) 1997-06-15

Family

ID=9425478

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93914481T ATE153342T1 (de) 1992-01-08 1992-12-29 Adenosinderivate, verfahren zu deren herstellung und pharmazeutische mittel

Country Status (25)

Country Link
US (2) US5229505A (de)
EP (1) EP0623138B1 (de)
JP (1) JP3224542B2 (de)
KR (1) KR100232672B1 (de)
AT (1) ATE153342T1 (de)
AU (1) AU661894B2 (de)
CA (1) CA2127472C (de)
CZ (1) CZ289047B6 (de)
DE (1) DE69219901T2 (de)
DK (1) DK0623138T3 (de)
EE (1) EE03087B1 (de)
ES (1) ES2105285T3 (de)
FI (1) FI106205B (de)
FR (1) FR2685918B1 (de)
GE (1) GEP19981357B (de)
GR (1) GR3024386T3 (de)
HU (1) HU221304B1 (de)
LV (1) LV11899B (de)
MD (1) MD502G2 (de)
NZ (1) NZ246904A (de)
RU (1) RU2129560C1 (de)
SK (1) SK282205B6 (de)
TW (1) TW254945B (de)
UA (1) UA44221C2 (de)
WO (1) WO1993014102A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2685918B1 (fr) * 1992-01-08 1995-06-23 Union Pharma Scient Appl Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.
WO1995018817A1 (fr) * 1994-01-07 1995-07-13 Laboratoires Upsa Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant
FR2714907B1 (fr) * 1994-01-07 1996-03-29 Union Pharma Scient Appl Nouveaux dérivés de l'Adénosine, leurs procédés de préparation, compositions pharmaceutiques les contenant.
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
FR2772271B1 (fr) * 1997-12-11 2000-09-01 Union Pharma Scient Appl Nouvelle association pharmaceutique a activite analgesique
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
KR20010071591A (ko) 1998-06-23 2001-07-28 그레이엄 브레레톤, 레슬리 에드워즈 2-(퓨린-9-일)-테트라히드로푸란-3,4-디올 유도체
JP2002173427A (ja) * 1998-09-01 2002-06-21 Yamasa Shoyu Co Ltd 眼疾患治療用医薬組成物
DE19924818A1 (de) * 1999-05-29 2000-11-30 Bayer Ag Substituierte Phenylcyclohexancarbonsäureamide
US6491666B1 (en) * 1999-11-17 2002-12-10 Microchips, Inc. Microfabricated devices for the delivery of molecules into a carrier fluid
AU2001278708A1 (en) * 2000-09-08 2002-03-22 Toa Eiyo Ltd. Adenosine derivatives and use thereof
EP1352910A1 (de) * 2002-04-10 2003-10-15 Grünenthal GmbH Neue Analoga von Nitrobenzylthioinosine
PE20060272A1 (es) 2004-05-24 2006-05-22 Glaxo Group Ltd (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE788958A (fr) * 1971-09-18 1973-03-19 Schering Ag Derives d'adenosine et leur procede de preparation
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
US5310731A (en) * 1984-06-28 1994-05-10 Whitby Research, Inc. N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
JPH0696534B2 (ja) * 1986-04-25 1994-11-30 ヘキストジヤパン株式会社 抗痴呆剤
AU8276187A (en) * 1986-10-31 1988-05-25 Warner-Lambert Company Selected n6-substituted adenosines having selective a2 binding activity
WO1988003148A2 (en) * 1986-10-31 1988-05-05 Warner-Lambert Company Heteroaromatic derivatives of adenoside
IL84414A0 (en) * 1986-11-14 1988-04-29 Ciba Geigy Ag N9-cyclopentyl-substituted adenine derivatives
SU1661367A1 (ru) * 1988-11-01 1991-07-07 Всесоюзный научно-исследовательский институт по креплению скважин и буровым растворам Способ гидрофобизации тампонажных материалов
ES2095960T3 (es) * 1990-09-25 1997-03-01 Rhone Poulenc Rorer Int Compuestos que tienen propiedades antihipertensivas y antiisquemicas.
FR2685918B1 (fr) * 1992-01-08 1995-06-23 Union Pharma Scient Appl Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.

Also Published As

Publication number Publication date
CZ164394A3 (en) 1995-02-15
AU3455093A (en) 1993-08-03
NZ246904A (en) 1995-04-27
MD502F1 (en) 1996-03-29
FI943222A (fi) 1994-08-18
LV11899B (lv) 1998-03-20
ES2105285T3 (es) 1997-10-16
SK282205B6 (sk) 2001-12-03
WO1993014102A1 (fr) 1993-07-22
US5229505A (en) 1993-07-20
DE69219901D1 (de) 1997-06-26
EP0623138A1 (de) 1994-11-09
UA44221C2 (uk) 2002-02-15
JP3224542B2 (ja) 2001-10-29
FI943222A0 (fi) 1994-07-06
RU94039545A (ru) 1997-04-27
HU221304B1 (en) 2002-09-28
FR2685918B1 (fr) 1995-06-23
SK81894A3 (en) 1995-04-12
LV11899A (lv) 1997-12-20
HU9402040D0 (en) 1994-09-28
CA2127472C (en) 2003-11-18
KR100232672B1 (ko) 1999-12-01
DK0623138T3 (da) 1997-12-15
TW254945B (de) 1995-08-21
EE03087B1 (et) 1998-04-15
GEP19981357B (en) 1998-08-25
MD502G2 (ro) 1996-11-30
CA2127472A1 (en) 1993-07-22
AU661894B2 (en) 1995-08-10
HUT68095A (en) 1995-05-29
EP0623138B1 (de) 1997-05-21
FR2685918A1 (fr) 1993-07-09
US5480983A (en) 1996-01-02
CZ289047B6 (cs) 2001-10-17
RU2129560C1 (ru) 1999-04-27
DE69219901T2 (de) 1997-11-13
FI106205B (fi) 2000-12-15
GR3024386T3 (en) 1997-11-28
JPH07502738A (ja) 1995-03-23

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UEP Publication of translation of european patent specification