MD502F1 - New adenozin derivatives, method for preparation, pharmaceutical baze compositions - Google Patents

New adenozin derivatives, method for preparation, pharmaceutical baze compositions

Info

Publication number
MD502F1
MD502F1 MD95-0111A MD950111A MD502F1 MD 502 F1 MD502 F1 MD 502F1 MD 950111 A MD950111 A MD 950111A MD 502 F1 MD502 F1 MD 502F1
Authority
MD
Moldova
Prior art keywords
adenozin
baze
pharmaceutical
derivatives
compositions
Prior art date
Application number
MD95-0111A
Other languages
Romanian (ro)
Other versions
MD502G2 (en
Inventor
Nicole Bru-Magniez
Timur Gungor
Jean-Marie Teulon
Original Assignee
Union Pharma Scient Appl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Union Pharma Scient Appl filed Critical Union Pharma Scient Appl
Publication of MD502F1 publication Critical patent/MD502F1/en
Publication of MD502G2 publication Critical patent/MD502G2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Prezenta inventie se refera la derivatii cu formula: <CH.FORM> precum si la sarurile lor aditive si la utilizarea lor in terapie, in special, ca analgetice si antihipertensive. Revendicari: 15 Tabele: 2
MD95-0111A 1992-01-08 1994-12-30 New adenozine derivatives, methods of obtainitg thereof, farmaceutical compositions on the base thereof MD502G2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9200138A FR2685918B1 (en) 1992-01-08 1992-01-08 NOVEL ADENOSINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Publications (2)

Publication Number Publication Date
MD502F1 true MD502F1 (en) 1996-03-29
MD502G2 MD502G2 (en) 1996-11-30

Family

ID=9425478

Family Applications (1)

Application Number Title Priority Date Filing Date
MD95-0111A MD502G2 (en) 1992-01-08 1994-12-30 New adenozine derivatives, methods of obtainitg thereof, farmaceutical compositions on the base thereof

Country Status (25)

Country Link
US (2) US5229505A (en)
EP (1) EP0623138B1 (en)
JP (1) JP3224542B2 (en)
KR (1) KR100232672B1 (en)
AT (1) ATE153342T1 (en)
AU (1) AU661894B2 (en)
CA (1) CA2127472C (en)
CZ (1) CZ289047B6 (en)
DE (1) DE69219901T2 (en)
DK (1) DK0623138T3 (en)
EE (1) EE03087B1 (en)
ES (1) ES2105285T3 (en)
FI (1) FI106205B (en)
FR (1) FR2685918B1 (en)
GE (1) GEP19981357B (en)
GR (1) GR3024386T3 (en)
HU (1) HU221304B1 (en)
LV (1) LV11899B (en)
MD (1) MD502G2 (en)
NZ (1) NZ246904A (en)
RU (1) RU2129560C1 (en)
SK (1) SK282205B6 (en)
TW (1) TW254945B (en)
UA (1) UA44221C2 (en)
WO (1) WO1993014102A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2685918B1 (en) * 1992-01-08 1995-06-23 Union Pharma Scient Appl NOVEL ADENOSINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2714907B1 (en) * 1994-01-07 1996-03-29 Union Pharma Scient Appl New adenosine derivatives, their preparation processes, pharmaceutical compositions containing them.
WO1995018817A1 (en) * 1994-01-07 1995-07-13 Laboratoires Upsa Novel adenosine derivatives, preparation methods therefor, and pharmaceutical compositions containing same
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
FR2772271B1 (en) * 1997-12-11 2000-09-01 Union Pharma Scient Appl NEW PHARMACEUTICAL ASSOCIATION WITH ANALGESIC ACTIVITY
YU44900A (en) 1998-01-31 2003-01-31 Glaxo Group Limited 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
CN1313861A (en) 1998-06-23 2001-09-19 葛兰素集团有限公司 2-(purin-9-YL)-tetrahydrofuran-3,4-diolderivatives
JP2002173427A (en) * 1998-09-01 2002-06-21 Yamasa Shoyu Co Ltd Pharmaceutical composition for treating eye diseases
DE19924818A1 (en) 1999-05-29 2000-11-30 Bayer Ag Substituted phenylcyclohexane carboxamides
JP2003513755A (en) * 1999-11-17 2003-04-15 マイクロチップス・インコーポレーテッド Microfabricated device for delivery of molecules into a carrier fluid
WO2002020539A1 (en) * 2000-09-08 2002-03-14 Toa Eiyo Ltd. Adenosine derivatives and use thereof
EP1352910A1 (en) * 2002-04-10 2003-10-15 Grünenthal GmbH New analogs of nitrobenzylthioinosine
AR049384A1 (en) 2004-05-24 2006-07-26 Glaxo Group Ltd PURINA DERIVATIVES
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE788958A (en) * 1971-09-18 1973-03-19 Schering Ag ADENOSINE DERIVATIVES AND THEIR PREPARATION PROCESS
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
US5310731A (en) * 1984-06-28 1994-05-10 Whitby Research, Inc. N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
JPH0696534B2 (en) * 1986-04-25 1994-11-30 ヘキストジヤパン株式会社 Anti-dementia agent
WO1988003147A1 (en) * 1986-10-31 1988-05-05 Warner-Lambert Company Selected n6-substituted adenosines having selective a2 binding activity
AU8274187A (en) * 1986-10-31 1988-05-25 Warner-Lambert Company Heteroaromatic derivatives of adenosine
EP0267878A1 (en) * 1986-11-14 1988-05-18 Ciba-Geigy Ag N9-cyclopentyl-substituted adenine derivatives
SU1661367A1 (en) * 1988-11-01 1991-07-07 Всесоюзный научно-исследовательский институт по креплению скважин и буровым растворам Method of hydrophobization of grouting materials
SG80526A1 (en) * 1990-09-25 2001-05-22 Rhone Poulenc Rorer Int Compounds having antihypertensive and anti- ischemic properies
FR2685918B1 (en) * 1992-01-08 1995-06-23 Union Pharma Scient Appl NOVEL ADENOSINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
DE69219901T2 (en) 1997-11-13
JP3224542B2 (en) 2001-10-29
AU661894B2 (en) 1995-08-10
NZ246904A (en) 1995-04-27
CZ164394A3 (en) 1995-02-15
HU221304B1 (en) 2002-09-28
MD502G2 (en) 1996-11-30
LV11899A (en) 1997-12-20
FI943222A0 (en) 1994-07-06
ATE153342T1 (en) 1997-06-15
AU3455093A (en) 1993-08-03
KR100232672B1 (en) 1999-12-01
SK282205B6 (en) 2001-12-03
EP0623138B1 (en) 1997-05-21
FR2685918A1 (en) 1993-07-09
EE03087B1 (en) 1998-04-15
UA44221C2 (en) 2002-02-15
RU94039545A (en) 1997-04-27
FI943222L (en) 1994-08-18
FR2685918B1 (en) 1995-06-23
US5229505A (en) 1993-07-20
TW254945B (en) 1995-08-21
ES2105285T3 (en) 1997-10-16
DK0623138T3 (en) 1997-12-15
EP0623138A1 (en) 1994-11-09
RU2129560C1 (en) 1999-04-27
HU9402040D0 (en) 1994-09-28
WO1993014102A1 (en) 1993-07-22
JPH07502738A (en) 1995-03-23
DE69219901D1 (en) 1997-06-26
GEP19981357B (en) 1998-08-25
CA2127472A1 (en) 1993-07-22
CA2127472C (en) 2003-11-18
HUT68095A (en) 1995-05-29
SK81894A3 (en) 1995-04-12
CZ289047B6 (en) 2001-10-17
GR3024386T3 (en) 1997-11-28
LV11899B (en) 1998-03-20
FI106205B (en) 2000-12-15
US5480983A (en) 1996-01-02

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Legal Events

Date Code Title Description
FG3A Granted patent for invention
IF99 Valid patent on 19990615

Free format text: EXPIRES: 20141230

MK4A Patent for invention expired