ATE122659T1 - Pyridinylcarbonylaminoalkyl-dihydro-oxo-pyridin , ihr verfahren zur herstellung und ihre verwendung. - Google Patents

Pyridinylcarbonylaminoalkyl-dihydro-oxo-pyridin , ihr verfahren zur herstellung und ihre verwendung.

Info

Publication number
ATE122659T1
ATE122659T1 AT93102220T AT93102220T ATE122659T1 AT E122659 T1 ATE122659 T1 AT E122659T1 AT 93102220 T AT93102220 T AT 93102220T AT 93102220 T AT93102220 T AT 93102220T AT E122659 T1 ATE122659 T1 AT E122659T1
Authority
AT
Austria
Prior art keywords
treatment
disturbances
hydrogen
compounds
loweralkyl
Prior art date
Application number
AT93102220T
Other languages
German (de)
English (en)
Inventor
Heinrich Dr Englert
Dieter Dr Mania
David Dr Wettlaufer
Erik Dr Klaus
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of ATE122659T1 publication Critical patent/ATE122659T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AT93102220T 1992-02-20 1993-02-12 Pyridinylcarbonylaminoalkyl-dihydro-oxo-pyridin , ihr verfahren zur herstellung und ihre verwendung. ATE122659T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92102828 1992-02-20

Publications (1)

Publication Number Publication Date
ATE122659T1 true ATE122659T1 (de) 1995-06-15

Family

ID=8209352

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93102220T ATE122659T1 (de) 1992-02-20 1993-02-12 Pyridinylcarbonylaminoalkyl-dihydro-oxo-pyridin , ihr verfahren zur herstellung und ihre verwendung.

Country Status (17)

Country Link
US (1) US5360808A (en10)
EP (1) EP0556738B1 (en10)
JP (1) JPH069560A (en10)
KR (1) KR930017895A (en10)
CN (1) CN1075480A (en10)
AT (1) ATE122659T1 (en10)
AU (1) AU3375993A (en10)
CA (1) CA2089955A1 (en10)
CZ (1) CZ403592A3 (en10)
DE (1) DE69300152D1 (en10)
FI (1) FI930716A (en10)
HU (1) HU9300463D0 (en10)
IL (1) IL104781A0 (en10)
MA (1) MA22806A1 (en10)
MX (1) MX9300915A (en10)
NO (1) NO930594L (en10)
ZA (1) ZA931185B (en10)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA02006131A (es) * 1999-12-21 2002-12-16 Monsanto Technology Llc Derivados de diacilo herbicidas de propilendiamina.
DE10205219A1 (de) * 2002-02-08 2003-08-21 Bayer Ag Chinoxalinone und ihre Verwendung
US6869966B2 (en) * 2002-09-30 2005-03-22 Banyu Pharmaceutical Co., Ltd. N-substituted-2-oxodihydropyridine derivatives
US20040127129A1 (en) * 2002-12-31 2004-07-01 Shuiyuan Luo Grooved-shape monofilaments and the fabrics made thereof
US8138209B2 (en) * 2005-07-13 2012-03-20 Jenrin Discovery, Inc. Substituted picolinamides as MAO-B inhibitors useful for treating obesity
US8314087B2 (en) 2007-02-16 2012-11-20 Amgen Inc. Nitrogen-containing heterocyclyl ketones and methods of use
KR101370185B1 (ko) 2008-12-23 2014-03-05 에프. 호프만-라 로슈 아게 P2x7 조절제로서의 디히드로피리돈 아미드
CA2745866A1 (en) 2008-12-23 2010-07-01 F.Hoffmann-La Roche Ag Dihydropyridone ureas as p2x7 modulators
WO2010072597A1 (en) 2008-12-23 2010-07-01 F. Hoffmann-La Roche Ag Dihydropyridone amides as p2x7 modulators
WO2010072605A1 (en) 2008-12-23 2010-07-01 F. Hoffmann-La Roche Ag Dihydropyridone amides as p2x7 modulators
US8153808B2 (en) 2008-12-23 2012-04-10 Roche Palo Alto Llc Dihydropyridone amides as P2X7 modulators
US8816085B2 (en) 2009-08-26 2014-08-26 Takeda Gmbh Methylpyrrolopyridinecarboxamides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2637477A1 (de) * 1976-08-20 1978-02-23 Hoechst Ag Dihydro-oxo-nicotinsaeuren und verfahren zu ihrer herstellung
US4297360A (en) * 1980-03-28 1981-10-27 Sterling Drug Inc. 5-(Pyridinyl)pyridine-2,3-diamines, preparation thereof and their cardiotonic use
NZ195564A (en) * 1979-11-26 1983-09-30 Sterling Drug Inc 5-pyridinyl-2(1h)-pyridinones pharmaceutical compositions intermediate pyridine compounds
IT8367883A0 (it) * 1982-08-23 1983-08-22 Rorer Int Overseas Composti cardiotonici del 2 piridone 5 biciclico eteroaril sostituito e relative composizioni farmaceutiche
GB8809481D0 (en) * 1988-04-21 1988-05-25 Smith Kline French Lab Chemical compounds

Also Published As

Publication number Publication date
CZ403592A3 (en) 1993-12-15
EP0556738B1 (en) 1995-05-17
IL104781A0 (en) 1993-06-10
NO930594L (no) 1993-08-23
KR930017895A (ko) 1993-09-20
AU3375993A (en) 1993-08-26
JPH069560A (ja) 1994-01-18
MA22806A1 (fr) 1993-10-01
ZA931185B (en) 1993-09-16
EP0556738A1 (en) 1993-08-25
NO930594D0 (no) 1993-02-19
US5360808A (en) 1994-11-01
HU9300463D0 (en) 1993-05-28
CA2089955A1 (en) 1993-08-21
CN1075480A (zh) 1993-08-25
FI930716A (fi) 1993-08-21
DE69300152D1 (de) 1995-06-22
FI930716A0 (fi) 1993-02-18
MX9300915A (es) 1993-09-01

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