ATE146176T1 - Benzo(b)thiophen-3-yl-piperazine, verfahren zur deren herstellung und ihre verwendung als arzneimittel - Google Patents
Benzo(b)thiophen-3-yl-piperazine, verfahren zur deren herstellung und ihre verwendung als arzneimittelInfo
- Publication number
- ATE146176T1 ATE146176T1 AT93107818T AT93107818T ATE146176T1 AT E146176 T1 ATE146176 T1 AT E146176T1 AT 93107818 T AT93107818 T AT 93107818T AT 93107818 T AT93107818 T AT 93107818T AT E146176 T1 ATE146176 T1 AT E146176T1
- Authority
- AT
- Austria
- Prior art keywords
- integer
- thiophen
- benzo
- piperazine
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/66—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/885,331 US5240927A (en) | 1992-05-19 | 1992-05-19 | Benzo[β]thiophen-3-yl piperazines as antipsychotic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE146176T1 true ATE146176T1 (de) | 1996-12-15 |
Family
ID=25386664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93107818T ATE146176T1 (de) | 1992-05-19 | 1993-05-13 | Benzo(b)thiophen-3-yl-piperazine, verfahren zur deren herstellung und ihre verwendung als arzneimittel |
Country Status (14)
Country | Link |
---|---|
US (1) | US5240927A (de) |
EP (1) | EP0570850B1 (de) |
JP (1) | JP2673089B2 (de) |
KR (1) | KR100258395B1 (de) |
AT (1) | ATE146176T1 (de) |
AU (1) | AU653311B2 (de) |
CA (1) | CA2096515C (de) |
DE (1) | DE69306467T2 (de) |
DK (1) | DK0570850T3 (de) |
ES (1) | ES2096800T3 (de) |
GR (1) | GR3022788T3 (de) |
MX (1) | MX9302889A (de) |
NZ (1) | NZ247624A (de) |
TW (1) | TW232018B (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4128690A1 (de) * | 1991-08-29 | 1993-03-04 | Boehringer Mannheim Gmbh | Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
US5272148A (en) * | 1992-09-09 | 1993-12-21 | Hoechst-Roussel Pharmaceuticals Incorporated | Heteroarenylpiperazines |
EP0732332B1 (de) * | 1995-03-17 | 2001-12-19 | Aventis Pharmaceuticals Inc. | Substituierte Benzylthienylpiperazine, ihre Anwendung als Arzneimittel und Verfahren für ihre Herstellung |
TWI329641B (en) * | 2005-08-31 | 2010-09-01 | Otsuka Pharma Co Ltd | (benzo[b]thiophen-4-yl)piperazine compounds, pharmaceutical compositions comprising the same, uses of the same and processes for preparing the same |
JP4785881B2 (ja) * | 2007-02-27 | 2011-10-05 | 大塚製薬株式会社 | 医薬 |
CN105061414B (zh) * | 2015-07-21 | 2019-01-01 | 杭州新博思生物医药有限公司 | 一锅法制备Brexpiprazole |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4366162A (en) * | 1977-11-09 | 1982-12-28 | Ab Ferrosan | Aryl ethers of N-alkyl-piperidines and acid addition salts thereof |
FR2475898A1 (fr) * | 1980-02-14 | 1981-08-21 | Andre Buzas | Medicament analgesique contenant de la 1-(3'-benzofuryl)-4-benzylpiperazine et son procede de preparation |
IE58370B1 (en) * | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
AU593284B2 (en) * | 1985-09-12 | 1990-02-08 | Pharmacia & Upjohn Company | C20 to c26 amino steroids |
GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
US4803203A (en) * | 1986-11-05 | 1989-02-07 | Warner-Lambert Company | Phenyl and heterocyclic piperazinyl alkoxy-benzheterocyclic compounds as antipsychotic agents |
EP0316723B1 (de) * | 1987-11-20 | 1992-09-30 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-[4(1-Substituierte-4-Piperazinyl)butyl]-4-Thiazolidinone, Verfahren zu deren Herstellung und ihre Anwendung als Arzneimittel |
GB8803419D0 (en) * | 1988-02-15 | 1988-03-16 | Erba Carlo Spa | 1 4-benzoxazine & 1 4-benzothiazine derivatives & process for their preparation |
DK158590D0 (da) * | 1990-07-02 | 1990-07-02 | Lundbeck & Co As H | Indolderivater |
US5143923B1 (en) * | 1991-04-29 | 1993-11-02 | Hoechst-Roussel Pharmaceuticals Incorporated | Benzoisothiazole-and benzisoxazole-3-carboxamides |
DE4128690A1 (de) * | 1991-08-29 | 1993-03-04 | Boehringer Mannheim Gmbh | Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
-
1992
- 1992-05-19 US US07/885,331 patent/US5240927A/en not_active Expired - Lifetime
-
1993
- 1993-04-21 TW TW082103038A patent/TW232018B/zh not_active IP Right Cessation
- 1993-05-13 DE DE69306467T patent/DE69306467T2/de not_active Expired - Fee Related
- 1993-05-13 ES ES93107818T patent/ES2096800T3/es not_active Expired - Lifetime
- 1993-05-13 EP EP93107818A patent/EP0570850B1/de not_active Expired - Lifetime
- 1993-05-13 AT AT93107818T patent/ATE146176T1/de not_active IP Right Cessation
- 1993-05-13 DK DK93107818.2T patent/DK0570850T3/da active
- 1993-05-14 NZ NZ247624A patent/NZ247624A/en unknown
- 1993-05-18 JP JP5115623A patent/JP2673089B2/ja not_active Expired - Lifetime
- 1993-05-18 CA CA002096515A patent/CA2096515C/en not_active Expired - Fee Related
- 1993-05-18 KR KR1019930008440A patent/KR100258395B1/ko not_active IP Right Cessation
- 1993-05-18 MX MX9302889A patent/MX9302889A/es not_active IP Right Cessation
- 1993-05-18 AU AU38604/93A patent/AU653311B2/en not_active Ceased
-
1997
- 1997-03-11 GR GR970400472T patent/GR3022788T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DK0570850T3 (da) | 1997-06-16 |
EP0570850A1 (de) | 1993-11-24 |
TW232018B (de) | 1994-10-11 |
JP2673089B2 (ja) | 1997-11-05 |
JPH069617A (ja) | 1994-01-18 |
KR940005621A (ko) | 1994-03-21 |
AU3860493A (en) | 1993-11-25 |
ES2096800T3 (es) | 1997-03-16 |
NZ247624A (en) | 1995-03-28 |
CA2096515C (en) | 2003-11-04 |
CA2096515A1 (en) | 1993-11-20 |
GR3022788T3 (en) | 1997-06-30 |
US5240927A (en) | 1993-08-31 |
AU653311B2 (en) | 1994-09-22 |
KR100258395B1 (en) | 2000-07-01 |
DE69306467D1 (de) | 1997-01-23 |
MX9302889A (es) | 1993-11-01 |
DE69306467T2 (de) | 1997-05-28 |
EP0570850B1 (de) | 1996-12-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |