DE69300152D1 - Pyridinylcarbonylaminoalkyl-Dihydro-Oxo-Pyridine, ihr Verfahren zur Herstellung und ihre Verwendung. - Google Patents
Pyridinylcarbonylaminoalkyl-Dihydro-Oxo-Pyridine, ihr Verfahren zur Herstellung und ihre Verwendung.Info
- Publication number
- DE69300152D1 DE69300152D1 DE69300152T DE69300152T DE69300152D1 DE 69300152 D1 DE69300152 D1 DE 69300152D1 DE 69300152 T DE69300152 T DE 69300152T DE 69300152 T DE69300152 T DE 69300152T DE 69300152 D1 DE69300152 D1 DE 69300152D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- disturbances
- hydrogen
- compounds
- loweralkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP92102828 | 1992-02-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69300152D1 true DE69300152D1 (de) | 1995-06-22 |
Family
ID=8209352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69300152T Expired - Lifetime DE69300152D1 (de) | 1992-02-20 | 1993-02-12 | Pyridinylcarbonylaminoalkyl-Dihydro-Oxo-Pyridine, ihr Verfahren zur Herstellung und ihre Verwendung. |
Country Status (17)
Country | Link |
---|---|
US (1) | US5360808A (en10) |
EP (1) | EP0556738B1 (en10) |
JP (1) | JPH069560A (en10) |
KR (1) | KR930017895A (en10) |
CN (1) | CN1075480A (en10) |
AT (1) | ATE122659T1 (en10) |
AU (1) | AU3375993A (en10) |
CA (1) | CA2089955A1 (en10) |
CZ (1) | CZ403592A3 (en10) |
DE (1) | DE69300152D1 (en10) |
FI (1) | FI930716A (en10) |
HU (1) | HU9300463D0 (en10) |
IL (1) | IL104781A0 (en10) |
MA (1) | MA22806A1 (en10) |
MX (1) | MX9300915A (en10) |
NO (1) | NO930594L (en10) |
ZA (1) | ZA931185B (en10) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1944801A (en) * | 1999-12-21 | 2001-07-03 | Monsanto Technology Llc | Herbicidal diacyl derivatives of propylene diamine |
DE10205219A1 (de) * | 2002-02-08 | 2003-08-21 | Bayer Ag | Chinoxalinone und ihre Verwendung |
US6869966B2 (en) * | 2002-09-30 | 2005-03-22 | Banyu Pharmaceutical Co., Ltd. | N-substituted-2-oxodihydropyridine derivatives |
US20040127129A1 (en) * | 2002-12-31 | 2004-07-01 | Shuiyuan Luo | Grooved-shape monofilaments and the fabrics made thereof |
WO2007008963A1 (en) * | 2005-07-13 | 2007-01-18 | Jenrin Discovery | Mao-b inhibitors useful for treating obesity |
US8314087B2 (en) | 2007-02-16 | 2012-11-20 | Amgen Inc. | Nitrogen-containing heterocyclyl ketones and methods of use |
JP2012513435A (ja) | 2008-12-23 | 2012-06-14 | エフ.ホフマン−ラ ロシュ アーゲー | P2x7調節薬としてのジヒドロピリドンアミド |
SG172336A1 (en) | 2008-12-23 | 2011-07-28 | Hoffmann La Roche | Dihydropyridone amides as p2x7 modulators |
SG172785A1 (en) | 2008-12-23 | 2011-08-29 | Hoffmann La Roche | Dihydropyridone amides as p2x7 modulators |
US8153808B2 (en) | 2008-12-23 | 2012-04-10 | Roche Palo Alto Llc | Dihydropyridone amides as P2X7 modulators |
BRPI0924059A2 (pt) | 2008-12-23 | 2015-07-07 | Hoffmann La Roche | Didro piridona amidas como moduladores de p2x7 |
EP2470531A1 (en) | 2009-08-26 | 2012-07-04 | Nycomed GmbH | Methylpyrrolopyridinecarboxamides |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2637477A1 (de) * | 1976-08-20 | 1978-02-23 | Hoechst Ag | Dihydro-oxo-nicotinsaeuren und verfahren zu ihrer herstellung |
IL61501A (en) * | 1979-11-26 | 1984-06-29 | Sterling Drug Inc | 5-(pyridinyl)-2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them |
US4297360A (en) * | 1980-03-28 | 1981-10-27 | Sterling Drug Inc. | 5-(Pyridinyl)pyridine-2,3-diamines, preparation thereof and their cardiotonic use |
IT8367883A0 (it) * | 1982-08-23 | 1983-08-22 | Rorer Int Overseas | Composti cardiotonici del 2 piridone 5 biciclico eteroaril sostituito e relative composizioni farmaceutiche |
GB8809481D0 (en) * | 1988-04-21 | 1988-05-25 | Smith Kline French Lab | Chemical compounds |
-
1992
- 1992-12-31 CZ CS924035A patent/CZ403592A3/cs unknown
-
1993
- 1993-02-12 DE DE69300152T patent/DE69300152D1/de not_active Expired - Lifetime
- 1993-02-12 EP EP93102220A patent/EP0556738B1/en not_active Expired - Lifetime
- 1993-02-12 AT AT93102220T patent/ATE122659T1/de not_active IP Right Cessation
- 1993-02-18 FI FI930716A patent/FI930716A/fi not_active Application Discontinuation
- 1993-02-18 KR KR1019930002218A patent/KR930017895A/ko not_active Application Discontinuation
- 1993-02-18 IL IL104781A patent/IL104781A0/xx unknown
- 1993-02-18 US US08/019,296 patent/US5360808A/en not_active Expired - Fee Related
- 1993-02-19 MX MX9300915A patent/MX9300915A/es unknown
- 1993-02-19 CN CN93101816A patent/CN1075480A/zh active Pending
- 1993-02-19 AU AU33759/93A patent/AU3375993A/en not_active Abandoned
- 1993-02-19 HU HU9300463A patent/HU9300463D0/hu unknown
- 1993-02-19 JP JP5029515A patent/JPH069560A/ja active Pending
- 1993-02-19 MA MA23099A patent/MA22806A1/fr unknown
- 1993-02-19 ZA ZA931185A patent/ZA931185B/xx unknown
- 1993-02-19 CA CA002089955A patent/CA2089955A1/en not_active Abandoned
- 1993-02-19 NO NO93930594A patent/NO930594L/no unknown
Also Published As
Publication number | Publication date |
---|---|
HU9300463D0 (en) | 1993-05-28 |
EP0556738A1 (en) | 1993-08-25 |
US5360808A (en) | 1994-11-01 |
KR930017895A (ko) | 1993-09-20 |
EP0556738B1 (en) | 1995-05-17 |
MX9300915A (es) | 1993-09-01 |
FI930716A0 (fi) | 1993-02-18 |
MA22806A1 (fr) | 1993-10-01 |
CZ403592A3 (en) | 1993-12-15 |
CN1075480A (zh) | 1993-08-25 |
ZA931185B (en) | 1993-09-16 |
FI930716A (fi) | 1993-08-21 |
NO930594L (no) | 1993-08-23 |
JPH069560A (ja) | 1994-01-18 |
AU3375993A (en) | 1993-08-26 |
IL104781A0 (en) | 1993-06-10 |
NO930594D0 (no) | 1993-02-19 |
CA2089955A1 (en) | 1993-08-21 |
ATE122659T1 (de) | 1995-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8372 | Publication of ep patent withdrawn |