ATE107353T1 - Blutplättchenlysat, verfahren zu seiner herstellung sowie ein solches lysat enthaltendes zellkulturmedium. - Google Patents
Blutplättchenlysat, verfahren zu seiner herstellung sowie ein solches lysat enthaltendes zellkulturmedium.Info
- Publication number
- ATE107353T1 ATE107353T1 AT89905220T AT89905220T ATE107353T1 AT E107353 T1 ATE107353 T1 AT E107353T1 AT 89905220 T AT89905220 T AT 89905220T AT 89905220 T AT89905220 T AT 89905220T AT E107353 T1 ATE107353 T1 AT E107353T1
- Authority
- AT
- Austria
- Prior art keywords
- lysate
- pct
- platelets
- cell culture
- platelet
- Prior art date
Links
- 239000006166 lysate Substances 0.000 title abstract 5
- 239000006143 cell culture medium Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000007788 liquid Substances 0.000 abstract 3
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
- 102000008946 Fibrinogen Human genes 0.000 abstract 1
- 108010049003 Fibrinogen Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 244000309466 calf Species 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 229940012952 fibrinogen Drugs 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/80—Undefined extracts from animals
- C12N2500/84—Undefined extracts from animals from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8801537A SE8801537D0 (sv) | 1988-04-26 | 1988-04-26 | Cellodlingsmedium samt forfarande for dess framstellning |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE107353T1 true ATE107353T1 (de) | 1994-07-15 |
Family
ID=20372119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89905220T ATE107353T1 (de) | 1988-04-26 | 1989-04-26 | Blutplättchenlysat, verfahren zu seiner herstellung sowie ein solches lysat enthaltendes zellkulturmedium. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5198357A (de) |
| EP (1) | EP0413727B1 (de) |
| JP (1) | JPH03505156A (de) |
| AT (1) | ATE107353T1 (de) |
| AU (1) | AU3539289A (de) |
| DE (1) | DE68916244T2 (de) |
| SE (1) | SE8801537D0 (de) |
| WO (1) | WO1989010398A1 (de) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5723443A (en) * | 1988-02-02 | 1998-03-03 | Hankyu-Kyoei Bussan Co. Ltd. | Lipid metabolism promoting agent and its use |
| JPH04198129A (ja) * | 1990-11-28 | 1992-07-17 | Sumitomo Pharmaceut Co Ltd | 活性型ビタミンd↓3類含有組成物 |
| ES2184236T3 (es) * | 1997-02-06 | 2003-04-01 | Therasense Inc | Sensor in vitro de analitos de pequeño volumen. |
| JP3521382B2 (ja) * | 1997-02-27 | 2004-04-19 | 日本たばこ産業株式会社 | 細胞間接着及びシグナル伝達を媒介する細胞表面分子 |
| DE19821060A1 (de) | 1997-09-23 | 1999-04-15 | Bundesrepublik Deutschland Let | Ko-stimulierendes Polypeptid von T-Zellen, monoklonale Antikörper sowie die Herstellung und deren Verwendung |
| JP4463418B2 (ja) * | 1997-09-23 | 2010-05-19 | ドイツ連邦共和国 | T細胞共同刺激性ポリペプチド、モノクローナル抗体、ならびにその製法および使用 |
| EP1740617B1 (de) | 2004-04-23 | 2013-10-16 | BUNDESREPUBLIK DEUTSCHLAND letztvertreten durch das Robert Koch-Institut vertreten durch seinen Präsidenten | Verfahren zur behandlung von erkrankungen, die mit t-zellen im zusammenhang stehen, durch eliminierung von icos-positiven zellen in vivo |
| US20060039991A1 (en) * | 2004-08-20 | 2006-02-23 | Alberto Gorrochategui Barrueta | Biological tissue regenerative agent and method for preparing and using same |
| EP1880206B1 (de) * | 2005-05-09 | 2012-11-14 | Affymetrix, Inc. | Multiplex-einfang von nukleinsäuren |
| US8632970B2 (en) | 2005-05-09 | 2014-01-21 | Affymetrix, Inc. | Multiplex capture of nucleic acids |
| WO2006124771A2 (en) * | 2005-05-12 | 2006-11-23 | Panomics, Inc. | Multiplex branched-chain dna assays |
| US20080038725A1 (en) * | 2005-06-20 | 2008-02-14 | Yuling Luo | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
| SE0501462L (sv) * | 2005-06-23 | 2006-09-26 | Proliff Ab | Förfarande för framställning av blodplättslysat |
| US7927798B2 (en) * | 2005-10-05 | 2011-04-19 | Panomics, Inc. | Detection of nucleic acids from whole blood |
| CA2640185A1 (en) * | 2006-01-24 | 2007-08-02 | Christopher J. Centeno | Mesenchymal stem cell isolation and transplantation method and system to be used in a clinical setting |
| WO2008034803A1 (en) * | 2006-09-18 | 2008-03-27 | Medizinische Universität Graz | Plasma-free platelet lysate for use as a supplement in cell cultures and for the preparation of cell therapeutics |
| US9095562B2 (en) | 2007-07-05 | 2015-08-04 | Regenerative Sciences, Inc. | Methods and compositions for optimized expansion and implantation of mesenchymal stem cells |
| US20110200642A1 (en) * | 2007-12-19 | 2011-08-18 | Regenerative Sciences, Llc | Compositions and Methods to Promote Implantation and Engrafment of Stem Cells |
| US20110052533A1 (en) * | 2008-03-14 | 2011-03-03 | Regenerative Sciences, Llc | Compositions and Methods for Cartilage Repair |
| EP2310006A4 (de) | 2008-07-03 | 2012-04-25 | Mayo Foundation | Krebsbehandlung |
| EP2334785B2 (de) * | 2008-09-16 | 2019-08-14 | Mayo Foundation For Medical Education And Research | Zusammensetzungen mit thrombozytengehalt |
| JP2012510874A (ja) | 2008-12-05 | 2012-05-17 | リジェネレイティブ サイエンシーズ, エルエルシー | 無血管組織の修復を促進するための方法及び組成物 |
| US20100168022A1 (en) * | 2008-12-11 | 2010-07-01 | Centeno Christopher J | Use of In-Vitro Culture to Design or Test Personalized Treatment Regimens |
| US20110054929A1 (en) * | 2009-09-01 | 2011-03-03 | Cell Solutions Colorado Llc | Stem Cell Marketplace |
| HUP0900603A2 (en) * | 2009-09-25 | 2012-02-28 | Biomarker Kft | Cell culture medium |
| US9113950B2 (en) | 2009-11-04 | 2015-08-25 | Regenerative Sciences, Llc | Therapeutic delivery device |
| EP3034625B1 (de) | 2010-10-21 | 2017-10-04 | Advanced Cell Diagnostics, Inc. | Hochsensitives verfahren für den in-situ-nachweis von nukleinsäuren |
| ES2792062T3 (es) | 2011-05-09 | 2020-11-06 | Mayo Found Medical Education & Res | Tratamientos contra el cáncer |
| US9788539B2 (en) | 2011-05-17 | 2017-10-17 | Velico Medical, Inc. | Platelet protection solution having beta-galactosidase and sialidase inhibitors |
| WO2012158983A2 (en) | 2011-05-17 | 2012-11-22 | Qiyong Peter Liu | Improved platelet storage using a sialidase inhibitor |
| ES2811085T7 (es) * | 2011-06-27 | 2021-11-29 | Univ Emory | Composiciones, usos y preparación de lisados de plaquetas |
| EP2540819A1 (de) * | 2011-06-27 | 2013-01-02 | Rheinisch-Westfälische Technische Hochschule Aachen (RWTH) | Verfahren zur Kultivierung von Zellen in einem Medium mit Plättchenlysat |
| US9133438B2 (en) | 2011-06-29 | 2015-09-15 | Biorestorative Therapies, Inc. | Brown fat cell compositions and methods |
| LT2729562T (lt) | 2011-07-06 | 2018-07-25 | Cell Therapy Limited | Mezodermos ląstelių linijos kamieninės ląstelės |
| ITRM20110500A1 (it) * | 2011-09-23 | 2013-03-24 | Futura Stem Cells Sa | Lisato piastrinico, usi di esso e metodo per la sua preparazione |
| AU2012342218B2 (en) | 2011-11-23 | 2017-03-02 | Cell Therapy Limited | Platelet lysate gel |
| ES2899643T3 (es) | 2012-10-01 | 2022-03-14 | Mayo Found Medical Education & Res | Tratamientos para el cáncer |
| EP2903430A1 (de) | 2012-10-05 | 2015-08-12 | Velico Medical, Inc. | Plättchenadditivlösung mit beta-galactosidase-inhibitor |
| EP2733200A1 (de) | 2012-11-15 | 2014-05-21 | Biorigen International SA | Zellkulturzusätze |
| KR20150113978A (ko) * | 2013-01-28 | 2015-10-08 | 리제너러티브 사이언시즈, 엘엘씨 | 혈소판 용해 및 활성화를 위한 디바이스 및 방법 |
| WO2014120886A1 (en) | 2013-01-30 | 2014-08-07 | Velico Medical, Inc. | Platelet additive solution having a self-assembling hydrogel-forming peptide |
| EP3795678B1 (de) | 2013-04-19 | 2023-07-12 | Biorestorative Therapies, Inc. | Stammzellen aus menschlichem braunen fettgewebe und verwendungen |
| JP6649257B2 (ja) * | 2013-08-27 | 2020-02-19 | クック・ジェネラル・バイオテクノロジー・エルエルシー | 濃厚血小板から誘導可能な生理活性組成物並びにその調製方法及び使用方法 |
| EP3143130B1 (de) | 2014-05-16 | 2024-03-06 | Mayo Foundation for Medical Education and Research | Zellkulturmedienzusammensetzungen für primärzellen |
| GB201410504D0 (en) | 2014-06-12 | 2014-07-30 | Cell Therapy Ltd | Immuno-modulaltory progenitor (IMP) cell |
| AU2015274408A1 (en) | 2014-06-13 | 2017-01-12 | Mayo Foundation For Medical Education And Research | Treating lymphomas |
| US10213513B2 (en) | 2014-06-16 | 2019-02-26 | Mayo Foundation For Medical Education And Research | Treating myelomas |
| US9446148B2 (en) | 2014-10-06 | 2016-09-20 | Mayo Foundation For Medical Education And Research | Carrier-antibody compositions and methods of making and using the same |
| GB201513996D0 (en) | 2015-08-07 | 2015-09-23 | Cell Therapy Ltd | Immuno-oncology mesodermal progenitor (IOMP) cell |
| TW201707725A (zh) | 2015-08-18 | 2017-03-01 | 美國馬友醫藥教育研究基金會 | 載體-抗體組合物及其製造及使用方法 |
| KR20170037379A (ko) * | 2015-09-25 | 2017-04-04 | (주)프로스테믹스 | 세포의 증식 촉진용 조성물 및 이를 포함하는 세포 배양용 배지 |
| TW201713360A (en) | 2015-10-06 | 2017-04-16 | Mayo Foundation | Methods of treating cancer using compositions of antibodies and carrier proteins |
| EP3362462B1 (de) | 2015-10-12 | 2021-07-21 | Advanced Cell Diagnostics, Inc. | In-situ-detektion von nukleotidvarianten bei proben mit hohem rauschen sowie zugehörige zusammensetzungen und verfahren |
| GB201518263D0 (en) | 2015-10-15 | 2015-12-02 | Oxford Bioelectronics Ltd | Method |
| US11571469B2 (en) | 2016-01-07 | 2023-02-07 | Mayo Foundation For Medical Education And Research | Methods of treating cancer with interferon wherein the cancer cells are HLA negative or have reduced HLA expression |
| US11351254B2 (en) | 2016-02-12 | 2022-06-07 | Mayo Foundation For Medical Education And Research | Hematologic cancer treatments |
| CA3018341A1 (en) | 2016-03-21 | 2017-09-28 | Mayo Foundation For Medical Education And Research | Methods for reducing toxicity of a chemotherapeutic drug |
| WO2017165439A1 (en) | 2016-03-21 | 2017-09-28 | Mayo Foundation For Medical Education And Research | Methods for improving the therapeutic index for a chemotherapeutic drug |
| US10618969B2 (en) | 2016-04-06 | 2020-04-14 | Mayo Foundation For Medical Education And Research | Carrier-binding agent compositions and methods of making and using the same |
| US20200325442A1 (en) | 2016-06-02 | 2020-10-15 | Pl Bioscience Gmbh | Method for producing a platelet-lysate-containing gel |
| EP3506950A1 (de) | 2016-09-01 | 2019-07-10 | Mayo Foundation for Medical Education and Research | Gegen t-zell-karzinome gerichtete verfahren und zusammensetzungen |
| CA3035378A1 (en) | 2016-09-01 | 2018-03-08 | Mayo Foundation For Medical Education And Research | Carrier-pd-l1 binding agent compositions for treating cancers |
| EP3509635A1 (de) | 2016-09-06 | 2019-07-17 | Vavotar Life Sciences LLC | Verfahren zur behandlung von dreifach negativem brustkrebs unter verwendung von zusammensetzungen aus antikörpern und trägerproteinen |
| AU2017324335A1 (en) | 2016-09-06 | 2019-03-28 | Mayo Foundation For Medical Education And Research | Methods of treating PD-L1 expressing cancer |
| EP3509643A1 (de) | 2016-09-06 | 2019-07-17 | Mayo Foundation for Medical Education and Research | Paclitaxel-albumin-bindende wirkstoffzusammensetzungen und verfahren zur verwendung und herstellung davon |
| CN109468262A (zh) * | 2018-10-30 | 2019-03-15 | 中国科学院苏州生物医学工程技术研究所 | 家畜血细胞制备动物细胞培养液的方法及其制得的动物细胞培养液的应用 |
| EP3911733B1 (de) | 2019-01-15 | 2024-08-21 | Cell Therapy Limited | Mesodermale killerzelle (mk) |
| GB201900554D0 (en) | 2019-01-15 | 2019-03-06 | Cell Therapy Ltd | Mesodermal killer (mk) cell |
| CN110484497A (zh) * | 2019-09-05 | 2019-11-22 | 中国人民解放军南部战区总医院 | 一种血小板裂解液及其制备方法和应用 |
| US11951134B2 (en) | 2019-09-30 | 2024-04-09 | North Carolina State University | Cationic platelet lysate compositions and related methods |
| CN116926001A (zh) * | 2022-04-06 | 2023-10-24 | 上海我武干细胞科技有限公司 | 血清替代物及其制备方法与应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8000527A (nl) * | 1980-01-29 | 1981-08-17 | Stichting Vrienden Van De Stic | Werkwijze voor het bevorderen van hybridisatie van cellen in vitro en van de produktie en uitscheiding van stoffen, gevormd door dergelijke celhybriden, werkwijze voor het bevorderen van de produktie van monoclonale antilichamen in vitro door toepassing van een hybridomatechniek, alsmede endotheelcellen en/of supernatant van endotheelcellen. |
| US4350687A (en) * | 1980-02-10 | 1982-09-21 | Research Corporation | Platelet derived cell growth factor |
| US4473552A (en) * | 1981-03-16 | 1984-09-25 | Jost Leonora I | Anaerobic method for preserving whole blood, tissue and components containing living mammalian cells |
| US4987079A (en) * | 1982-07-06 | 1991-01-22 | Wilbur D. Smith | Composition and method for in vitro cell culture |
| US4520107A (en) * | 1982-09-28 | 1985-05-28 | Polydex Chemicals Ltd. | Tissue culture and cell growth-promoting material and its method of manufacture |
| US5045468A (en) * | 1986-12-12 | 1991-09-03 | Cell Enterprises, Inc. | Protein-free culture medium which promotes hybridoma growth |
| NO162160C (no) * | 1987-01-09 | 1989-11-15 | Medi Cult As | Serumfritt vekstmedium, samt anvendelse derav. |
| US4959308A (en) * | 1987-08-27 | 1990-09-25 | Board Of Regents, The University Of Texas System | Immunoassay for antibodies binding platelets |
-
1988
- 1988-04-26 SE SE8801537A patent/SE8801537D0/xx unknown
-
1989
- 1989-04-26 US US07/634,113 patent/US5198357A/en not_active Expired - Fee Related
- 1989-04-26 AT AT89905220T patent/ATE107353T1/de not_active IP Right Cessation
- 1989-04-26 DE DE68916244T patent/DE68916244T2/de not_active Expired - Fee Related
- 1989-04-26 EP EP89905220A patent/EP0413727B1/de not_active Expired - Lifetime
- 1989-04-26 JP JP1504957A patent/JPH03505156A/ja active Pending
- 1989-04-26 AU AU35392/89A patent/AU3539289A/en not_active Abandoned
- 1989-04-26 WO PCT/SE1989/000232 patent/WO1989010398A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0413727A1 (de) | 1991-02-27 |
| DE68916244T2 (de) | 1995-02-09 |
| DE68916244D1 (de) | 1994-07-21 |
| US5198357A (en) | 1993-03-30 |
| AU3539289A (en) | 1989-11-24 |
| SE8801537D0 (sv) | 1988-04-26 |
| WO1989010398A1 (en) | 1989-11-02 |
| EP0413727B1 (de) | 1994-06-15 |
| JPH03505156A (ja) | 1991-11-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |