ATA100677A - Verfahren zur herstellung von neuen cephalos- porinantibiotika - Google Patents

Verfahren zur herstellung von neuen cephalos- porinantibiotika

Info

Publication number
ATA100677A
ATA100677A AT100677A AT100677A ATA100677A AT A100677 A ATA100677 A AT A100677A AT 100677 A AT100677 A AT 100677A AT 100677 A AT100677 A AT 100677A AT A100677 A ATA100677 A AT A100677A
Authority
AT
Austria
Prior art keywords
porinantibiotics
cephalos
producing new
producing
new
Prior art date
Application number
AT100677A
Other languages
English (en)
Other versions
AT358727B (de
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27254745&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATA100677(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB6009/76A external-priority patent/GB1571683A/en
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Priority to AT695679A priority Critical patent/AT361627B/de
Publication of ATA100677A publication Critical patent/ATA100677A/de
Application granted granted Critical
Publication of AT358727B publication Critical patent/AT358727B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT100677A 1976-02-16 1977-02-15 Verfahren zur herstellung von neuen cephalos- porinantibiotika AT358727B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT695679A AT361627B (de) 1976-02-16 1979-10-25 Verfahren zur herstellung von neuen cephalos- porinantibiotika

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB6009/76A GB1571683A (en) 1976-02-16 1976-02-16 Ester derivatives of cefuroxime
GB2730276 1976-06-30
GB2730176 1976-06-30

Publications (2)

Publication Number Publication Date
ATA100677A true ATA100677A (de) 1980-02-15
AT358727B AT358727B (de) 1980-09-25

Family

ID=27254745

Family Applications (1)

Application Number Title Priority Date Filing Date
AT100677A AT358727B (de) 1976-02-16 1977-02-15 Verfahren zur herstellung von neuen cephalos- porinantibiotika

Country Status (16)

Country Link
US (1) US4267320A (de)
JP (1) JPS52100494A (de)
AT (1) AT358727B (de)
AU (1) AU514236B2 (de)
CA (1) CA1094545A (de)
CH (2) CH628901A5 (de)
CY (1) CY1181A (de)
DE (1) DE2706413C2 (de)
DK (1) DK149062C (de)
FR (1) FR2340950A1 (de)
HK (1) HK17185A (de)
IL (1) IL51450A (de)
KE (1) KE3260A (de)
NL (2) NL185209C (de)
SE (1) SE431986B (de)
YU (1) YU40977B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1093549A (en) * 1976-02-16 1981-01-13 Michael Gregson Cephalosporin antibiotics
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
GB1602736A (en) * 1977-08-12 1981-11-18 Glaxo Operations Ltd A-acetoxyethyl esters of 3-carbamoyloxymethyl-7-(2-(fur-2-yl)-2-methoxyiminoacetamido)ceph-3-em-4-carboxylic acids
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
GB8320521D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
JPS60190783A (ja) * 1983-12-21 1985-09-28 Sumitomo Seiyaku Kk セフエム系化合物
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
GB8810394D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
GB8810393D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
JPH0586375U (ja) * 1991-07-11 1993-11-22 田中食品機械株式会社 ゴルフ練習用マット
JPH0541572U (ja) * 1991-11-15 1993-06-08 コナミ株式会社 遊戯機器用起伏形成装置
IT1277426B1 (it) * 1995-08-03 1997-11-10 Acs Dobfar Spa Forma cristallina biodisponibile del cefuroxima axetil
CN1111537C (zh) * 1997-05-15 2003-06-18 第一制糖株式会社 高纯晶形头孢呋辛1-乙酰氧乙酯的制备方法
IN186539B (de) * 1997-09-29 2001-09-29 Ranbaxy Lab Ltd
EP0937727B1 (de) * 1998-02-20 2002-01-30 Fako Ilaclari A.S. Verfahren zur Herstellung vom löslichen kristallinen Cefuroxim axetil
US6384213B1 (en) 1998-10-23 2002-05-07 Ranbaxy Laboratories Limited Process for preparing a pure, pharmacopoeial grade amorphous form of cefuroxime axetil
WO2000056286A1 (en) 1999-03-19 2000-09-28 Ranbaxy Laboratories Limited Process for the preparation of a bioavailable oral dosage form of cefuroxime axetil
IN190831B (de) 1999-03-19 2003-08-23 Ranbaxy Lab Ltd
CA2280925A1 (en) 1999-07-29 2001-01-29 Bernard Charles Sherman Stabilized cefuroxime axetil
IN190849B (de) * 2000-07-17 2003-08-23 Ranbaxy Lab Ltd
AT411996B (de) * 2000-09-11 2004-08-26 Sandoz Ag Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
JP2004536870A (ja) * 2001-07-25 2004-12-09 ルピン・リミテッド セフロキシムアキセチルの改良された調製方法
ITMI20011763A1 (it) * 2001-08-10 2003-02-10 Antibioticos Spa Processo di preparazione di cefuroxime axelite ad elevata purezza
HRP20020923A2 (en) * 2001-11-23 2003-10-31 Glaxo Group Ltd Pharmaceutical composition
KR100552567B1 (ko) * 2003-08-23 2006-02-15 한국유나이티드제약 주식회사 수분 흡수에 안정하고 빠르게 붕해되는 세푸록심 악세틸을포함하는 정제의 조성물 및 제조 방법
CN1295234C (zh) * 2004-11-15 2007-01-17 中山大学 一种头孢呋辛酯非对映异构体的分离方法
DE102005019458A1 (de) 2005-04-25 2006-10-26 Grünenthal GmbH Darreichungsform mit verbesserter Freisetzung von Cefuroximaxetil
DE102006019619A1 (de) * 2006-04-25 2007-10-31 Grünenthal GmbH Kristalline Modifikation von Cefuroximaxetil
WO2013038323A1 (en) 2011-09-13 2013-03-21 Unimark Remedies Ltd. Taste masked pharmaceutical compositions of cefuroxime axetil
CN111732599A (zh) * 2020-07-08 2020-10-02 江苏正大清江制药有限公司 一种合成头孢呋辛酯二聚体的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1310642A (en) 1970-11-09 1973-03-21 Pfizer Alpha-sulfo-and alpha-sulfoalkylacylcephalosporins
US3870713A (en) * 1970-12-07 1975-03-11 Pfizer Phosphono substituted alkylcephalosporins
CA996929A (en) * 1971-04-05 1976-09-14 Kohzi Nakano Acyloxyalkyl ester derivatives of penicillin
US3974153A (en) * 1971-05-14 1976-08-10 Glaxo Laboratories Limited 7-Hydrocarbonoxy imino-acetamido-3-carbamoyloxy methylceph-3-em-4 carboxylic acids
BE794844A (fr) * 1972-02-24 1973-08-01 Pfizer Alpha-carboxy-2-thienylmethylpenicilline et alpha-carboxy-2-thienylmethylcephalosporine,leurs esters et leurs sels
PL98296B1 (pl) 1973-02-07 1978-04-29 Politechnika Gdanskapo Sposob otrzymywania estrow acetoksymetylowych cefalosporyn
US3962227A (en) * 1973-02-23 1976-06-08 Eli Lilly And Company 3-halo cephalosporins
AR207148A1 (es) * 1974-05-02 1976-09-15 Rhone Poulenc Ind Procedimiento para la preparacion de un nuevo derivado de la cefalosporina

Also Published As

Publication number Publication date
SE431986B (sv) 1984-03-12
CY1181A (en) 1983-10-07
NL7701568A (nl) 1977-08-18
NL930073I2 (nl) 1993-11-01
HK17185A (en) 1985-03-22
FR2340950B1 (de) 1980-02-01
CH634328A5 (de) 1983-01-31
DE2706413C2 (de) 1986-08-28
IL51450A (en) 1980-11-30
CA1094545A (en) 1981-01-27
NL185209B (nl) 1989-09-18
IL51450A0 (en) 1977-04-29
JPS633868B2 (de) 1988-01-26
FR2340950A1 (fr) 1977-09-09
NL185209C (nl) 1990-02-16
KE3260A (en) 1983-03-25
NL930073I1 (nl) 1993-09-16
AU2228877A (en) 1978-08-24
YU40977B (en) 1986-10-31
CH628901A5 (de) 1982-03-31
AT358727B (de) 1980-09-25
SE7701668L (sv) 1977-08-17
AU514236B2 (en) 1981-01-29
DE2706413A1 (de) 1977-08-18
JPS52100494A (en) 1977-08-23
YU41177A (en) 1982-06-30
DK149062C (da) 1986-06-16
DK149062B (da) 1986-01-06
DK63877A (da) 1977-08-17
US4267320A (en) 1981-05-12

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Legal Events

Date Code Title Description
EFA Change in the company name
SZA Application filed for a certificate of protection

Free format text: SZ40/94, 941109

REN Ceased due to non-payment of the annual fee
ELA Expired due to lapse of time
EZF Grant of a certificate of protection

Free format text: SZ 40/1994, 19941109, EXPIRES:20030215