YU40977B - Improvements relating to cepnalospoprinic antibiotics - Google Patents

Improvements relating to cepnalospoprinic antibiotics

Info

Publication number
YU40977B
YU40977B YU411/77A YU41177A YU40977B YU 40977 B YU40977 B YU 40977B YU 411/77 A YU411/77 A YU 411/77A YU 41177 A YU41177 A YU 41177A YU 40977 B YU40977 B YU 40977B
Authority
YU
Yugoslavia
Prior art keywords
cepnalospoprinic
antibiotics
improvements relating
relating
cepnalospoprinic antibiotics
Prior art date
Application number
YU411/77A
Other languages
English (en)
Other versions
YU41177A (en
Inventor
M Gregson
R B Sykes
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27254745&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU40977(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB6009/76A external-priority patent/GB1571683A/en
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Priority to SI7710411A priority Critical patent/SI7710411A8/sl
Publication of YU41177A publication Critical patent/YU41177A/xx
Publication of YU40977B publication Critical patent/YU40977B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
YU411/77A 1976-02-16 1977-02-15 Improvements relating to cepnalospoprinic antibiotics YU40977B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SI7710411A SI7710411A8 (sl) 1976-02-16 1977-02-15 Postopek za pridobivanje estrov (6r,7r)-3-karbamoiloksi-met1l-7-/(z)-2-(fur-2-il)-2- alkoksiiminoacetamido/cef-3-em-4-karboksilne kisline

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB6009/76A GB1571683A (en) 1976-02-16 1976-02-16 Ester derivatives of cefuroxime
GB2730276 1976-06-30
GB2730176 1976-06-30

Publications (2)

Publication Number Publication Date
YU41177A YU41177A (en) 1982-06-30
YU40977B true YU40977B (en) 1986-10-31

Family

ID=27254745

Family Applications (1)

Application Number Title Priority Date Filing Date
YU411/77A YU40977B (en) 1976-02-16 1977-02-15 Improvements relating to cepnalospoprinic antibiotics

Country Status (16)

Country Link
US (1) US4267320A (xx)
JP (1) JPS52100494A (xx)
AT (1) AT358727B (xx)
AU (1) AU514236B2 (xx)
CA (1) CA1094545A (xx)
CH (2) CH628901A5 (xx)
CY (1) CY1181A (xx)
DE (1) DE2706413C2 (xx)
DK (1) DK149062C (xx)
FR (1) FR2340950A1 (xx)
HK (1) HK17185A (xx)
IL (1) IL51450A (xx)
KE (1) KE3260A (xx)
NL (2) NL185209C (xx)
SE (1) SE431986B (xx)
YU (1) YU40977B (xx)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1093549A (en) * 1976-02-16 1981-01-13 Michael Gregson Cephalosporin antibiotics
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
GB1602736A (en) * 1977-08-12 1981-11-18 Glaxo Operations Ltd A-acetoxyethyl esters of 3-carbamoyloxymethyl-7-(2-(fur-2-yl)-2-methoxyiminoacetamido)ceph-3-em-4-carboxylic acids
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
GB8320521D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
JPS60190783A (ja) * 1983-12-21 1985-09-28 Sumitomo Seiyaku Kk セフエム系化合物
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
GB8810394D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
GB8810393D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
JPH0586375U (ja) * 1991-07-11 1993-11-22 田中食品機械株式会社 ゴルフ練習用マット
JPH0541572U (ja) * 1991-11-15 1993-06-08 コナミ株式会社 遊戯機器用起伏形成装置
IT1277426B1 (it) * 1995-08-03 1997-11-10 Acs Dobfar Spa Forma cristallina biodisponibile del cefuroxima axetil
CN1111537C (zh) * 1997-05-15 2003-06-18 第一制糖株式会社 高纯晶形头孢呋辛1－乙酰氧乙酯的制备方法
IN186539B (xx) * 1997-09-29 2001-09-29 Ranbaxy Lab Ltd
EP0937727B1 (de) * 1998-02-20 2002-01-30 Fako Ilaclari A.S. Verfahren zur Herstellung vom löslichen kristallinen Cefuroxim axetil
US6384213B1 (en) 1998-10-23 2002-05-07 Ranbaxy Laboratories Limited Process for preparing a pure, pharmacopoeial grade amorphous form of cefuroxime axetil
WO2000056286A1 (en) 1999-03-19 2000-09-28 Ranbaxy Laboratories Limited Process for the preparation of a bioavailable oral dosage form of cefuroxime axetil
IN190831B (xx) 1999-03-19 2003-08-23 Ranbaxy Lab Ltd
CA2280925A1 (en) 1999-07-29 2001-01-29 Bernard Charles Sherman Stabilized cefuroxime axetil
IN190849B (xx) * 2000-07-17 2003-08-23 Ranbaxy Lab Ltd
AT411996B (de) * 2000-09-11 2004-08-26 Sandoz Ag Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
JP2004536870A (ja) * 2001-07-25 2004-12-09 ルピン・リミテッド セフロキシムアキセチルの改良された調製方法
ITMI20011763A1 (it) * 2001-08-10 2003-02-10 Antibioticos Spa Processo di preparazione di cefuroxime axelite ad elevata purezza
HRP20020923A2 (en) * 2001-11-23 2003-10-31 Glaxo Group Ltd Pharmaceutical composition
KR100552567B1 (ko) * 2003-08-23 2006-02-15 한국유나이티드제약 주식회사 수분 흡수에 안정하고 빠르게 붕해되는 세푸록심 악세틸을포함하는 정제의 조성물 및 제조 방법
CN1295234C (zh) * 2004-11-15 2007-01-17 中山大学 一种头孢呋辛酯非对映异构体的分离方法
DE102005019458A1 (de) 2005-04-25 2006-10-26 Grünenthal GmbH Darreichungsform mit verbesserter Freisetzung von Cefuroximaxetil
DE102006019619A1 (de) * 2006-04-25 2007-10-31 Grünenthal GmbH Kristalline Modifikation von Cefuroximaxetil
WO2013038323A1 (en) 2011-09-13 2013-03-21 Unimark Remedies Ltd. Taste masked pharmaceutical compositions of cefuroxime axetil
CN111732599A (zh) * 2020-07-08 2020-10-02 江苏正大清江制药有限公司 一种合成头孢呋辛酯二聚体的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1310642A (en) 1970-11-09 1973-03-21 Pfizer Alpha-sulfo-and alpha-sulfoalkylacylcephalosporins
US3870713A (en) * 1970-12-07 1975-03-11 Pfizer Phosphono substituted alkylcephalosporins
CA996929A (en) * 1971-04-05 1976-09-14 Kohzi Nakano Acyloxyalkyl ester derivatives of penicillin
US3974153A (en) * 1971-05-14 1976-08-10 Glaxo Laboratories Limited 7-Hydrocarbonoxy imino-acetamido-3-carbamoyloxy methylceph-3-em-4 carboxylic acids
BE794844A (fr) * 1972-02-24 1973-08-01 Pfizer Alpha-carboxy-2-thienylmethylpenicilline et alpha-carboxy-2-thienylmethylcephalosporine,leurs esters et leurs sels
PL98296B1 (pl) 1973-02-07 1978-04-29 Politechnika Gdanskapo Sposob otrzymywania estrow acetoksymetylowych cefalosporyn
US3962227A (en) * 1973-02-23 1976-06-08 Eli Lilly And Company 3-halo cephalosporins
AR207148A1 (es) * 1974-05-02 1976-09-15 Rhone Poulenc Ind Procedimiento para la preparacion de un nuevo derivado de la cefalosporina

Also Published As

Publication number Publication date
SE431986B (sv) 1984-03-12
CY1181A (en) 1983-10-07
NL7701568A (nl) 1977-08-18
NL930073I2 (nl) 1993-11-01
HK17185A (en) 1985-03-22
FR2340950B1 (xx) 1980-02-01
CH634328A5 (de) 1983-01-31
DE2706413C2 (de) 1986-08-28
IL51450A (en) 1980-11-30
CA1094545A (en) 1981-01-27
NL185209B (nl) 1989-09-18
IL51450A0 (en) 1977-04-29
JPS633868B2 (xx) 1988-01-26
FR2340950A1 (fr) 1977-09-09
NL185209C (nl) 1990-02-16
KE3260A (en) 1983-03-25
NL930073I1 (nl) 1993-09-16
AU2228877A (en) 1978-08-24
CH628901A5 (de) 1982-03-31
AT358727B (de) 1980-09-25
SE7701668L (sv) 1977-08-17
ATA100677A (de) 1980-02-15
AU514236B2 (en) 1981-01-29
DE2706413A1 (de) 1977-08-18
JPS52100494A (en) 1977-08-23
YU41177A (en) 1982-06-30
DK149062C (da) 1986-06-16
DK149062B (da) 1986-01-06
DK63877A (da) 1977-08-17
US4267320A (en) 1981-05-12

Similar Documents

Publication Publication Date Title
YU41177A (en) Improvements relating to cephalosporinic antibiotics
ZA775905B (en) Improvements relating to 1-aryloxy-2-hydroxy-3-alkyleneaminopropanes
ZA772233B (en) Improvements relating to substituted fluoroacylresorcins
JPS5358500A (en) Novel zeolitefuu1
JPS52128365A (en) Antibiotics compounds
JPS52131596A (en) Antibiotics
JPS5326329A (en) Antibiotics
PH13880A (en) Novel aryltrifluoroethylamines
ZA773288B (en) Antibiotic bl580delta
ZA777087B (en) Improvements in or relating to antibiotics
ZA775816B (en) Improvements relating to pyridobenzodiazepinones
ZA77715B (en) 7-substituted-ureido 3-carbamoyloxymethylcephalosporins antibiotics
JPS52105193A (en) Antibiotics
JPS5344615A (en) Silverrcontaining antibiotic
ZA777586B (en) Novel o-propyloximes
JPS52105293A (en) Antibiotic composition
JPS5320492A (en) Novel antibiotic
JPS539791A (en) Novel 77alphaa oxyiminoacycephalosporin
JPS533533A (en) Antibiotic composition
JPS5392796A (en) Antibiotics
JPS5326328A (en) Antibiotics
JPS5283992A (en) Novel antibiotic
JPS5326395A (en) Novel antibiotic
ZA777423B (en) Novel d-homosteroids
JPS533532A (en) Antibiotic composition