AT509267A1 - Organische verbindungen zur regulierung von vektoriellen ionenkanälen - Google Patents
Organische verbindungen zur regulierung von vektoriellen ionenkanälen Download PDFInfo
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- AT509267A1 AT509267A1 AT0004110A AT412010A AT509267A1 AT 509267 A1 AT509267 A1 AT 509267A1 AT 0004110 A AT0004110 A AT 0004110A AT 412010 A AT412010 A AT 412010A AT 509267 A1 AT509267 A1 AT 509267A1
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- Prior art keywords
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- amino acid
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0004110A AT509267A1 (de) | 2010-01-14 | 2010-01-14 | Organische verbindungen zur regulierung von vektoriellen ionenkanälen |
| JP2012548306A JP5771220B2 (ja) | 2010-01-14 | 2011-01-12 | ベクトルイオンチャネルを調節するための有機化合物 |
| DK11705798.4T DK2523968T3 (da) | 2010-01-14 | 2011-01-12 | Cykliske peptider til regulering af vektorielle ionkanaler |
| NZ600818A NZ600818A (en) | 2010-01-14 | 2011-01-12 | Cyclic peptides for the regulation of vectorial ion channels |
| CN201180005765.9A CN102770442B (zh) | 2010-01-14 | 2011-01-12 | 用于调节载体离子通道的有机化合物 |
| RU2012134322/04A RU2538597C2 (ru) | 2010-01-14 | 2011-01-12 | Органические соединения для регуляции векторных ионных каналов |
| US13/522,204 US8754049B2 (en) | 2010-01-14 | 2011-01-12 | Organic compound for the regulation of vectorial ion channels |
| ES11705798.4T ES2525381T3 (es) | 2010-01-14 | 2011-01-12 | Péptidos cíclicos para la regulación de canales iónicos vectoriales |
| EP11705798.4A EP2523968B1 (de) | 2010-01-14 | 2011-01-12 | Zyklische peptide zur regulierung von vektoriellen ionenkanalen |
| PL11705798T PL2523968T3 (pl) | 2010-01-14 | 2011-01-12 | Cykliczne peptydy do regulowania nośnikowych kanałów jonowych |
| KR1020127018445A KR101865420B1 (ko) | 2010-01-14 | 2011-01-12 | 벡터적 이온 채널의 조절을 위한 유기화합물 |
| PCT/AT2011/000014 WO2011085423A1 (de) | 2010-01-14 | 2011-01-12 | Zyklische peptide zur regulierung von vektoriellen ionenkanälen |
| CA2785185A CA2785185C (en) | 2010-01-14 | 2011-01-12 | Organic compounds for the regulation of vectorial ion channels |
| HK13101462.2A HK1174341B (en) | 2010-01-14 | 2011-01-12 | Cyclic peptides for regulation of vectorial ion channels |
| AU2011206907A AU2011206907B2 (en) | 2010-01-14 | 2011-01-12 | Organic compounds for the regulation of vectorial ion channels |
| BR112012017093A BR112012017093A2 (pt) | 2010-01-14 | 2011-01-12 | compostos orgânicos para a regulação de canais de íons vetoriais |
| IL220924A IL220924B (en) | 2010-01-14 | 2012-07-12 | Organic compounds for the regulation of vectorial ion channels |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0004110A AT509267A1 (de) | 2010-01-14 | 2010-01-14 | Organische verbindungen zur regulierung von vektoriellen ionenkanälen |
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| AT509267A1 true AT509267A1 (de) | 2011-07-15 |
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| AT0004110A AT509267A1 (de) | 2010-01-14 | 2010-01-14 | Organische verbindungen zur regulierung von vektoriellen ionenkanälen |
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| EP (1) | EP2523968B1 (enExample) |
| JP (1) | JP5771220B2 (enExample) |
| KR (1) | KR101865420B1 (enExample) |
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| ES (1) | ES2525381T3 (enExample) |
| IL (1) | IL220924B (enExample) |
| NZ (1) | NZ600818A (enExample) |
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| RU (1) | RU2538597C2 (enExample) |
| WO (1) | WO2011085423A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015132294A1 (en) * | 2014-03-04 | 2015-09-11 | Apeptico Forschung Und Entwicklung Gmbh | Attenuation of intrapulmonary inflammation |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2679239A1 (de) | 2012-06-28 | 2014-01-01 | Apeptico Forschung und Entwicklung GmbH | Pharmazeutische Zusammensetzung zur Behandlung der durch Sauerstoffarmut und verringerten Luftdruck vermittelten pulmonalen Form der Höhenkrankheit |
| JP6335279B2 (ja) * | 2013-04-23 | 2018-05-30 | アペプティコ フオルシユング ウント アントウィクラング ゲーエムベーハー | 式ｘ１−ｇｑｒｅｔｐｅｇａｅａｋｐｗｙ−ｘ２の環状ペプチドを含んでなる医薬組成物および体外肺処置のための使用 |
| US12004506B2 (en) | 2013-04-23 | 2024-06-11 | Apeptico Forschung Und Entwicklung Gmbh | Pharmaceutical composition comprising a cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2 and use for extracorporeal lung treatment |
| DK2988768T3 (da) * | 2013-04-23 | 2021-06-21 | Apeptico Forschung & Entwicklung Gmbh | Lyofilisat indeholdende et cyklisk peptid med Formel X1-GQRETPEGAEAKPWY-X2 til behandling af pulmonære ødemer |
| CN108025038B (zh) * | 2015-09-14 | 2022-02-01 | 阿佩普蒂科研究和开发有限责任公司 | 治疗1b型pha的环状多肽 |
Family Cites Families (13)
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| US5968753A (en) * | 1994-06-14 | 1999-10-19 | Nexell Therapeutics, Inc. | Positive and positive/negative cell selection mediated by peptide release |
| NZ509604A (en) | 1998-08-14 | 2003-05-30 | Innogenetics N | TNF-derived peptides for use in treating oedema |
| FR2839514A1 (fr) * | 2002-05-07 | 2003-11-14 | Centre Nat Rech Scient | Nouveaux peptides cycliques, leur utilisation comme agents anti-microbiens |
| EP1781323B1 (en) | 2004-08-06 | 2010-02-17 | Nycomed GmbH | Composition comprising a pulmonary surfactant and a tnf-derived peptide |
| CN101003520A (zh) * | 2007-01-12 | 2007-07-25 | 陈志龙 | 一种缬氨酸丁酰联苯化合物 |
| CN101007791A (zh) * | 2007-01-12 | 2007-08-01 | 东华大学 | 一种氨基酸联苯化合物 |
| EP2009023A1 (en) * | 2007-06-04 | 2008-12-31 | Rentschler Beteiligungs GmbH | Novel peptides and their use for the treatment of edema |
| AT506151B1 (de) * | 2007-12-12 | 2010-01-15 | Apeptico Forschung Und Entwick | Fusionsprotein |
| AT506150B1 (de) * | 2007-12-12 | 2010-01-15 | Apeptico Forschung Und Entwick | Zyklisches und cystein-freies peptid |
| CN101298432B (zh) * | 2008-05-30 | 2010-12-22 | 广州市星业科技发展有限公司 | L-吡咯烷酮羧酸钠的制备方法 |
| WO2009149278A1 (en) * | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| AT507953B1 (de) * | 2009-03-05 | 2011-02-15 | Apeptico Forschung & Entwicklung Gmbh | Verfahren zur vermeidung und zur behandlung einer hyperpermeabilität |
| DK2397151T3 (en) * | 2010-06-21 | 2015-05-18 | Apeptico Forschung & Entwicklung Gmbh | The treatment of the vascular complications of diabetes |
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2010
- 2010-01-14 AT AT0004110A patent/AT509267A1/de not_active Application Discontinuation
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2011
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- 2011-01-12 CA CA2785185A patent/CA2785185C/en active Active
- 2011-01-12 PL PL11705798T patent/PL2523968T3/pl unknown
- 2011-01-12 BR BR112012017093A patent/BR112012017093A2/pt not_active IP Right Cessation
- 2011-01-12 ES ES11705798.4T patent/ES2525381T3/es active Active
- 2011-01-12 EP EP11705798.4A patent/EP2523968B1/de active Active
- 2011-01-12 DK DK11705798.4T patent/DK2523968T3/da active
- 2011-01-12 AU AU2011206907A patent/AU2011206907B2/en not_active Ceased
- 2011-01-12 US US13/522,204 patent/US8754049B2/en active Active
- 2011-01-12 NZ NZ600818A patent/NZ600818A/en not_active IP Right Cessation
- 2011-01-12 KR KR1020127018445A patent/KR101865420B1/ko active Active
- 2011-01-12 CN CN201180005765.9A patent/CN102770442B/zh active Active
- 2011-01-12 JP JP2012548306A patent/JP5771220B2/ja active Active
- 2011-01-12 RU RU2012134322/04A patent/RU2538597C2/ru not_active IP Right Cessation
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2012
- 2012-07-12 IL IL220924A patent/IL220924B/en active IP Right Grant
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015132294A1 (en) * | 2014-03-04 | 2015-09-11 | Apeptico Forschung Und Entwicklung Gmbh | Attenuation of intrapulmonary inflammation |
| CN106061495A (zh) * | 2014-03-04 | 2016-10-26 | 阿佩普蒂科研究和开发有限责任公司 | 肺内炎症的减弱 |
| CN106061495B (zh) * | 2014-03-04 | 2020-02-07 | 阿佩普蒂科研究和开发有限责任公司 | 肺内炎症的减弱 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2523968A1 (de) | 2012-11-21 |
| JP2013517224A (ja) | 2013-05-16 |
| EP2523968B1 (de) | 2014-09-10 |
| ES2525381T3 (es) | 2014-12-23 |
| AU2011206907B2 (en) | 2016-06-02 |
| HK1174341A1 (en) | 2013-06-07 |
| WO2011085423A1 (de) | 2011-07-21 |
| RU2012134322A (ru) | 2014-02-20 |
| US20130072444A1 (en) | 2013-03-21 |
| CA2785185A1 (en) | 2011-07-21 |
| IL220924B (en) | 2018-04-30 |
| AU2011206907A1 (en) | 2012-06-21 |
| CN102770442B (zh) | 2015-09-23 |
| CN102770442A (zh) | 2012-11-07 |
| RU2538597C2 (ru) | 2015-01-10 |
| BR112012017093A2 (pt) | 2016-11-29 |
| NZ600818A (en) | 2014-02-28 |
| DK2523968T3 (da) | 2014-11-03 |
| PL2523968T3 (pl) | 2015-03-31 |
| KR20120134100A (ko) | 2012-12-11 |
| JP5771220B2 (ja) | 2015-08-26 |
| CA2785185C (en) | 2019-02-19 |
| US8754049B2 (en) | 2014-06-17 |
| KR101865420B1 (ko) | 2018-07-13 |
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