NZ600818A - Cyclic peptides for the regulation of vectorial ion channels - Google Patents
Cyclic peptides for the regulation of vectorial ion channelsInfo
- Publication number
- NZ600818A NZ600818A NZ600818A NZ60081811A NZ600818A NZ 600818 A NZ600818 A NZ 600818A NZ 600818 A NZ600818 A NZ 600818A NZ 60081811 A NZ60081811 A NZ 60081811A NZ 600818 A NZ600818 A NZ 600818A
- Authority
- NZ
- New Zealand
- Prior art keywords
- amino acid
- regulation
- ion channels
- cyclic peptides
- terminally
- Prior art date
Links
- 102000001189 Cyclic Peptides Human genes 0.000 title 1
- 108010069514 Cyclic Peptides Proteins 0.000 title 1
- 102000004310 Ion Channels Human genes 0.000 title 1
- 150000001413 amino acids Chemical group 0.000 abstract 7
- -1 cyclic organic compound Chemical class 0.000 abstract 2
- 238000006798 ring closing metathesis reaction Methods 0.000 abstract 2
- AHLPHDHHMVZTML-BYPYZUCNSA-N L-Ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 abstract 1
- AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 abstract 1
- UTJLXEIPEHZYQJ-UHFFFAOYSA-N Ornithine Natural products OC(=O)C(C)CCCN UTJLXEIPEHZYQJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960003104 ornithine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0004110A AT509267A1 (de) | 2010-01-14 | 2010-01-14 | Organische verbindungen zur regulierung von vektoriellen ionenkanälen |
| PCT/AT2011/000014 WO2011085423A1 (de) | 2010-01-14 | 2011-01-12 | Zyklische peptide zur regulierung von vektoriellen ionenkanälen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ600818A true NZ600818A (en) | 2014-02-28 |
Family
ID=43970939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ600818A NZ600818A (en) | 2010-01-14 | 2011-01-12 | Cyclic peptides for the regulation of vectorial ion channels |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8754049B2 (enExample) |
| EP (1) | EP2523968B1 (enExample) |
| JP (1) | JP5771220B2 (enExample) |
| KR (1) | KR101865420B1 (enExample) |
| CN (1) | CN102770442B (enExample) |
| AT (1) | AT509267A1 (enExample) |
| AU (1) | AU2011206907B2 (enExample) |
| BR (1) | BR112012017093A2 (enExample) |
| CA (1) | CA2785185C (enExample) |
| DK (1) | DK2523968T3 (enExample) |
| ES (1) | ES2525381T3 (enExample) |
| IL (1) | IL220924B (enExample) |
| NZ (1) | NZ600818A (enExample) |
| PL (1) | PL2523968T3 (enExample) |
| RU (1) | RU2538597C2 (enExample) |
| WO (1) | WO2011085423A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2679239A1 (de) | 2012-06-28 | 2014-01-01 | Apeptico Forschung und Entwicklung GmbH | Pharmazeutische Zusammensetzung zur Behandlung der durch Sauerstoffarmut und verringerten Luftdruck vermittelten pulmonalen Form der Höhenkrankheit |
| JP6335279B2 (ja) * | 2013-04-23 | 2018-05-30 | アペプティコ フオルシユング ウント アントウィクラング ゲーエムベーハー | 式ｘ１−ｇｑｒｅｔｐｅｇａｅａｋｐｗｙ−ｘ２の環状ペプチドを含んでなる医薬組成物および体外肺処置のための使用 |
| US12004506B2 (en) | 2013-04-23 | 2024-06-11 | Apeptico Forschung Und Entwicklung Gmbh | Pharmaceutical composition comprising a cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2 and use for extracorporeal lung treatment |
| DK2988768T3 (da) * | 2013-04-23 | 2021-06-21 | Apeptico Forschung & Entwicklung Gmbh | Lyofilisat indeholdende et cyklisk peptid med Formel X1-GQRETPEGAEAKPWY-X2 til behandling af pulmonære ødemer |
| WO2015132294A1 (en) * | 2014-03-04 | 2015-09-11 | Apeptico Forschung Und Entwicklung Gmbh | Attenuation of intrapulmonary inflammation |
| CN108025038B (zh) * | 2015-09-14 | 2022-02-01 | 阿佩普蒂科研究和开发有限责任公司 | 治疗1b型pha的环状多肽 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968753A (en) * | 1994-06-14 | 1999-10-19 | Nexell Therapeutics, Inc. | Positive and positive/negative cell selection mediated by peptide release |
| NZ509604A (en) | 1998-08-14 | 2003-05-30 | Innogenetics N | TNF-derived peptides for use in treating oedema |
| FR2839514A1 (fr) * | 2002-05-07 | 2003-11-14 | Centre Nat Rech Scient | Nouveaux peptides cycliques, leur utilisation comme agents anti-microbiens |
| EP1781323B1 (en) | 2004-08-06 | 2010-02-17 | Nycomed GmbH | Composition comprising a pulmonary surfactant and a tnf-derived peptide |
| CN101003520A (zh) * | 2007-01-12 | 2007-07-25 | 陈志龙 | 一种缬氨酸丁酰联苯化合物 |
| CN101007791A (zh) * | 2007-01-12 | 2007-08-01 | 东华大学 | 一种氨基酸联苯化合物 |
| EP2009023A1 (en) * | 2007-06-04 | 2008-12-31 | Rentschler Beteiligungs GmbH | Novel peptides and their use for the treatment of edema |
| AT506151B1 (de) * | 2007-12-12 | 2010-01-15 | Apeptico Forschung Und Entwick | Fusionsprotein |
| AT506150B1 (de) * | 2007-12-12 | 2010-01-15 | Apeptico Forschung Und Entwick | Zyklisches und cystein-freies peptid |
| CN101298432B (zh) * | 2008-05-30 | 2010-12-22 | 广州市星业科技发展有限公司 | L-吡咯烷酮羧酸钠的制备方法 |
| WO2009149278A1 (en) * | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| AT507953B1 (de) * | 2009-03-05 | 2011-02-15 | Apeptico Forschung & Entwicklung Gmbh | Verfahren zur vermeidung und zur behandlung einer hyperpermeabilität |
| DK2397151T3 (en) * | 2010-06-21 | 2015-05-18 | Apeptico Forschung & Entwicklung Gmbh | The treatment of the vascular complications of diabetes |
-
2010
- 2010-01-14 AT AT0004110A patent/AT509267A1/de not_active Application Discontinuation
-
2011
- 2011-01-12 WO PCT/AT2011/000014 patent/WO2011085423A1/de not_active Ceased
- 2011-01-12 CA CA2785185A patent/CA2785185C/en active Active
- 2011-01-12 PL PL11705798T patent/PL2523968T3/pl unknown
- 2011-01-12 BR BR112012017093A patent/BR112012017093A2/pt not_active IP Right Cessation
- 2011-01-12 ES ES11705798.4T patent/ES2525381T3/es active Active
- 2011-01-12 EP EP11705798.4A patent/EP2523968B1/de active Active
- 2011-01-12 DK DK11705798.4T patent/DK2523968T3/da active
- 2011-01-12 AU AU2011206907A patent/AU2011206907B2/en not_active Ceased
- 2011-01-12 US US13/522,204 patent/US8754049B2/en active Active
- 2011-01-12 NZ NZ600818A patent/NZ600818A/en not_active IP Right Cessation
- 2011-01-12 KR KR1020127018445A patent/KR101865420B1/ko active Active
- 2011-01-12 CN CN201180005765.9A patent/CN102770442B/zh active Active
- 2011-01-12 JP JP2012548306A patent/JP5771220B2/ja active Active
- 2011-01-12 RU RU2012134322/04A patent/RU2538597C2/ru not_active IP Right Cessation
-
2012
- 2012-07-12 IL IL220924A patent/IL220924B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP2523968A1 (de) | 2012-11-21 |
| JP2013517224A (ja) | 2013-05-16 |
| EP2523968B1 (de) | 2014-09-10 |
| ES2525381T3 (es) | 2014-12-23 |
| AU2011206907B2 (en) | 2016-06-02 |
| HK1174341A1 (en) | 2013-06-07 |
| WO2011085423A1 (de) | 2011-07-21 |
| RU2012134322A (ru) | 2014-02-20 |
| US20130072444A1 (en) | 2013-03-21 |
| CA2785185A1 (en) | 2011-07-21 |
| IL220924B (en) | 2018-04-30 |
| AT509267A1 (de) | 2011-07-15 |
| AU2011206907A1 (en) | 2012-06-21 |
| CN102770442B (zh) | 2015-09-23 |
| CN102770442A (zh) | 2012-11-07 |
| RU2538597C2 (ru) | 2015-01-10 |
| BR112012017093A2 (pt) | 2016-11-29 |
| DK2523968T3 (da) | 2014-11-03 |
| PL2523968T3 (pl) | 2015-03-31 |
| KR20120134100A (ko) | 2012-12-11 |
| JP5771220B2 (ja) | 2015-08-26 |
| CA2785185C (en) | 2019-02-19 |
| US8754049B2 (en) | 2014-06-17 |
| KR101865420B1 (ko) | 2018-07-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| LAPS | Patent lapsed |