PL2523968T3 - Cykliczne peptydy do regulowania nośnikowych kanałów jonowych - Google Patents

Cykliczne peptydy do regulowania nośnikowych kanałów jonowych

Info

Publication number
PL2523968T3
PL2523968T3 PL11705798T PL11705798T PL2523968T3 PL 2523968 T3 PL2523968 T3 PL 2523968T3 PL 11705798 T PL11705798 T PL 11705798T PL 11705798 T PL11705798 T PL 11705798T PL 2523968 T3 PL2523968 T3 PL 2523968T3
Authority
PL
Poland
Prior art keywords
regulation
ion channels
cyclic peptides
vectorial ion
vectorial
Prior art date
Application number
PL11705798T
Other languages
English (en)
Polish (pl)
Inventor
Bernhard Fischer
Rudolf Lucas
Susan Tzotzos
Original Assignee
Apeptico Forschung & Entwicklung Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apeptico Forschung & Entwicklung Gmbh filed Critical Apeptico Forschung & Entwicklung Gmbh
Publication of PL2523968T3 publication Critical patent/PL2523968T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL11705798T 2010-01-14 2011-01-12 Cykliczne peptydy do regulowania nośnikowych kanałów jonowych PL2523968T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT0004110A AT509267A1 (de) 2010-01-14 2010-01-14 Organische verbindungen zur regulierung von vektoriellen ionenkanälen
EP11705798.4A EP2523968B1 (de) 2010-01-14 2011-01-12 Zyklische peptide zur regulierung von vektoriellen ionenkanalen
PCT/AT2011/000014 WO2011085423A1 (de) 2010-01-14 2011-01-12 Zyklische peptide zur regulierung von vektoriellen ionenkanälen

Publications (1)

Publication Number Publication Date
PL2523968T3 true PL2523968T3 (pl) 2015-03-31

Family

ID=43970939

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11705798T PL2523968T3 (pl) 2010-01-14 2011-01-12 Cykliczne peptydy do regulowania nośnikowych kanałów jonowych

Country Status (16)

Country Link
US (1) US8754049B2 (enExample)
EP (1) EP2523968B1 (enExample)
JP (1) JP5771220B2 (enExample)
KR (1) KR101865420B1 (enExample)
CN (1) CN102770442B (enExample)
AT (1) AT509267A1 (enExample)
AU (1) AU2011206907B2 (enExample)
BR (1) BR112012017093A2 (enExample)
CA (1) CA2785185C (enExample)
DK (1) DK2523968T3 (enExample)
ES (1) ES2525381T3 (enExample)
IL (1) IL220924B (enExample)
NZ (1) NZ600818A (enExample)
PL (1) PL2523968T3 (enExample)
RU (1) RU2538597C2 (enExample)
WO (1) WO2011085423A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2679239A1 (de) * 2012-06-28 2014-01-01 Apeptico Forschung und Entwicklung GmbH Pharmazeutische Zusammensetzung zur Behandlung der durch Sauerstoffarmut und verringerten Luftdruck vermittelten pulmonalen Form der Höhenkrankheit
US12004506B2 (en) 2013-04-23 2024-06-11 Apeptico Forschung Und Entwicklung Gmbh Pharmaceutical composition comprising a cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2 and use for extracorporeal lung treatment
AU2014257678A1 (en) * 2013-04-23 2015-10-15 Apeptico Forschung Und Entwicklung Gmbh Lyophilisate containing a cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2
CN105188735A (zh) * 2013-04-23 2015-12-23 阿佩普蒂科研究和开发有限责任公司 包含式x1-gqretpegaeakpwy-x2的环肽的药物组合物及其体外处理肺的用途
WO2015132294A1 (en) * 2014-03-04 2015-09-11 Apeptico Forschung Und Entwicklung Gmbh Attenuation of intrapulmonary inflammation
EP3349779B1 (en) * 2015-09-14 2020-04-29 APEPTICO Forschung und Entwicklung GmbH Cyclic polypeptide for the treatment of pha type 1b

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017719A (en) * 1994-06-14 2000-01-25 Nexell Therapeutics, Inc. Positive and positive/negative cell selection mediated by peptide release
HU227661B1 (hu) 1998-08-14 2011-10-28 Rudolf Lucas Dr TNF-eredetû peptidek ödéma kezelésére
FR2839514A1 (fr) * 2002-05-07 2003-11-14 Centre Nat Rech Scient Nouveaux peptides cycliques, leur utilisation comme agents anti-microbiens
CA2575513C (en) 2004-08-06 2014-09-16 Altana Pharma Ag Composition comprising a pulmonary surfactant and a tnf-derived peptide
CN101003520A (zh) * 2007-01-12 2007-07-25 陈志龙 一种缬氨酸丁酰联苯化合物
CN101007791A (zh) * 2007-01-12 2007-08-01 东华大学 一种氨基酸联苯化合物
EP2009023A1 (en) * 2007-06-04 2008-12-31 Rentschler Beteiligungs GmbH Novel peptides and their use for the treatment of edema
AT506151B1 (de) * 2007-12-12 2010-01-15 Apeptico Forschung Und Entwick Fusionsprotein
AT506150B1 (de) * 2007-12-12 2010-01-15 Apeptico Forschung Und Entwick Zyklisches und cystein-freies peptid
CN101298432B (zh) * 2008-05-30 2010-12-22 广州市星业科技发展有限公司 L-吡咯烷酮羧酸钠的制备方法
ES2559840T3 (es) * 2008-06-04 2016-02-16 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AT507953B1 (de) * 2009-03-05 2011-02-15 Apeptico Forschung & Entwicklung Gmbh Verfahren zur vermeidung und zur behandlung einer hyperpermeabilität
DK2397151T3 (en) * 2010-06-21 2015-05-18 Apeptico Forschung & Entwicklung Gmbh The treatment of the vascular complications of diabetes

Also Published As

Publication number Publication date
CA2785185A1 (en) 2011-07-21
CN102770442A (zh) 2012-11-07
CN102770442B (zh) 2015-09-23
JP2013517224A (ja) 2013-05-16
EP2523968A1 (de) 2012-11-21
AT509267A1 (de) 2011-07-15
IL220924B (en) 2018-04-30
AU2011206907A1 (en) 2012-06-21
KR20120134100A (ko) 2012-12-11
JP5771220B2 (ja) 2015-08-26
AU2011206907B2 (en) 2016-06-02
KR101865420B1 (ko) 2018-07-13
CA2785185C (en) 2019-02-19
ES2525381T3 (es) 2014-12-23
RU2538597C2 (ru) 2015-01-10
BR112012017093A2 (pt) 2016-11-29
US8754049B2 (en) 2014-06-17
RU2012134322A (ru) 2014-02-20
NZ600818A (en) 2014-02-28
DK2523968T3 (da) 2014-11-03
WO2011085423A1 (de) 2011-07-21
HK1174341A1 (en) 2013-06-07
US20130072444A1 (en) 2013-03-21
EP2523968B1 (de) 2014-09-10

Similar Documents

Publication Publication Date Title
GB2550808B (en) Ion mobility separator for mass spectrometers
ZA201300244B (en) Hydrogen membrane separator
HUE053333T2 (hu) Átvezetés
SG10201600517YA (en) Protection of microbial cells from acidic degradation
IL225617A0 (en) Compounds that are similar to cyclosporine
ZA201504602B (en) Compounds for protection of cells
GB201012651D0 (en) Peptides
GB2549036B (en) RF ion guides
GB201110916D0 (en) Electrical distribution system
IL225616A0 (en) Compounds that are similar to cyclosporine
GB2486173B (en) Separator
IL220924B (en) Organic compounds for the regulation of vectorial ion channels
ZA201400681B (en) Off-gas channel
AU343259S (en) Disposable equipment for cell separation
IL234574B (en) Peptides to control emulsification
IL213611A0 (en) Secure fast channel changing
GB201105330D0 (en) Cell stack system
GB2499173B (en) Improved voltage regulation apparatus
GB201122244D0 (en) Insulators
EP2787567A4 (en) FUEL CELL SYSTEM
GB201109449D0 (en) Control of cell search procedure
GB2503542B (en) Voltage supplies for mass spectrometers
AU5402P (en) Sunsurfaz Petunia hybrid
AU4894P (en) BHTUN31501 Petunia hybrid
TWM402449U (en) Improved structure for voltage regulator