AT396425B - Verfahren zur herstellung von zusammensetzungen, die stoffe anhaltend abgeben und so erhaltene zusammensetzungen - Google Patents

Verfahren zur herstellung von zusammensetzungen, die stoffe anhaltend abgeben und so erhaltene zusammensetzungen Download PDF

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Publication number
AT396425B
AT396425B AT0152591A AT152591A AT396425B AT 396425 B AT396425 B AT 396425B AT 0152591 A AT0152591 A AT 0152591A AT 152591 A AT152591 A AT 152591A AT 396425 B AT396425 B AT 396425B
Authority
AT
Austria
Prior art keywords
gel
particles
phase
mpa
active ingredient
Prior art date
Application number
AT0152591A
Other languages
German (de)
English (en)
Other versions
ATA152591A (de
Inventor
Jean-Marc Ruiz
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of ATA152591A publication Critical patent/ATA152591A/de
Application granted granted Critical
Publication of AT396425B publication Critical patent/AT396425B/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Glanulating (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT0152591A 1990-08-01 1991-07-31 Verfahren zur herstellung von zusammensetzungen, die stoffe anhaltend abgeben und so erhaltene zusammensetzungen AT396425B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909016885A GB9016885D0 (en) 1990-08-01 1990-08-01 Sustained release pharmaceutical compositions

Publications (2)

Publication Number Publication Date
ATA152591A ATA152591A (de) 1993-01-15
AT396425B true AT396425B (de) 1993-09-27

Family

ID=10679993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0152591A AT396425B (de) 1990-08-01 1991-07-31 Verfahren zur herstellung von zusammensetzungen, die stoffe anhaltend abgeben und so erhaltene zusammensetzungen

Country Status (30)

Country Link
US (1) US5213812A (cg-RX-API-DMAC7.html)
JP (1) JP2818704B2 (cg-RX-API-DMAC7.html)
KR (1) KR920003962A (cg-RX-API-DMAC7.html)
AT (1) AT396425B (cg-RX-API-DMAC7.html)
AU (2) AU649696B2 (cg-RX-API-DMAC7.html)
BE (1) BE1004772A3 (cg-RX-API-DMAC7.html)
CA (1) CA2048270C (cg-RX-API-DMAC7.html)
CH (1) CH682715A5 (cg-RX-API-DMAC7.html)
DE (1) DE4125542A1 (cg-RX-API-DMAC7.html)
DK (1) DK175756B1 (cg-RX-API-DMAC7.html)
ES (1) ES2046083B1 (cg-RX-API-DMAC7.html)
FI (1) FI104149B1 (cg-RX-API-DMAC7.html)
FR (1) FR2665360B1 (cg-RX-API-DMAC7.html)
GB (1) GB9016885D0 (cg-RX-API-DMAC7.html)
GR (1) GR1001512B (cg-RX-API-DMAC7.html)
HK (1) HK33294A (cg-RX-API-DMAC7.html)
IE (1) IE65124B1 (cg-RX-API-DMAC7.html)
IN (1) IN178446B (cg-RX-API-DMAC7.html)
IT (1) IT1251788B (cg-RX-API-DMAC7.html)
LU (1) LU87982A1 (cg-RX-API-DMAC7.html)
MA (1) MA22245A1 (cg-RX-API-DMAC7.html)
MY (1) MY107500A (cg-RX-API-DMAC7.html)
NL (1) NL194637C (cg-RX-API-DMAC7.html)
NO (1) NO300158B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ238981A (cg-RX-API-DMAC7.html)
OA (1) OA09387A (cg-RX-API-DMAC7.html)
PT (1) PT98497B (cg-RX-API-DMAC7.html)
SE (1) SE505734C2 (cg-RX-API-DMAC7.html)
TN (1) TNSN91067A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA915565B (cg-RX-API-DMAC7.html)

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US5569467A (en) * 1993-05-15 1996-10-29 Societe De Conseils De Recherches Et D'applications (S.C.R.A.S.) Process for the preparation of microballs and microballs thus obtained
WO1995022963A1 (en) * 1994-02-28 1995-08-31 Medinova Medical Consulting Gmbh Drug targeting system, method for preparing same and its use
US5980945A (en) * 1996-01-16 1999-11-09 Societe De Conseils De Recherches Et D'applications Scientifique S.A. Sustained release drug formulations
DE19604744A1 (de) 1996-02-09 1997-08-14 Henkel Kgaa Technische Di-/Triglyceridgemische
DE19617137C1 (de) * 1996-04-29 1997-02-27 Henkel Kgaa Verwendung von Copolymerestern für die Herstellung von Mikrosphären
EP0930874A2 (en) * 1996-10-09 1999-07-28 Takeda Chemical Industries, Ltd. A method for producing a microparticle
AR012448A1 (es) * 1997-04-18 2000-10-18 Ipsen Pharma Biotech Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada
WO1999052708A1 (en) 1998-04-13 1999-10-21 Luminex Corporation Liquid labeling with fluorescent microparticles
KR100707710B1 (ko) * 1998-12-16 2007-04-18 아벤티스 파마슈티칼스 인크. 생분해가능한 중합체로 캡슐화된 세로토닌 수용체 길항제및 이의 제조방법
AU5644400A (en) * 1999-09-24 2001-03-29 Rohm And Haas Company Pellet compositions
US6458387B1 (en) * 1999-10-18 2002-10-01 Epic Therapeutics, Inc. Sustained release microspheres
DE60138641D1 (de) 2000-10-27 2009-06-18 Baxter Healthcare Sa Herstellung von mikrokügelchen
US20080026068A1 (en) * 2001-08-16 2008-01-31 Baxter Healthcare S.A. Pulmonary delivery of spherical insulin microparticles
ATE395042T1 (de) * 2001-08-16 2008-05-15 Baxter Int Darreichungsformen welche mikropartikel und treibgas enthalten
FR2848113B1 (fr) * 2002-12-04 2005-02-25 Oreal Stabilisation de principes actifs aromatiques par des polymeres aromatiques
US20040166077A1 (en) * 2002-12-04 2004-08-26 L'oreal Process for treating keratin materials with aromatic active principles
US20050142205A1 (en) * 2003-07-18 2005-06-30 Julia Rashba-Step Methods for encapsulating small spherical particles prepared by controlled phase separation
KR101137785B1 (ko) * 2003-07-18 2012-04-25 백스터 인터내셔널 인코포레이티드 제어된 상 분리에 의해 제조된 작은 구형 입자의 제조방법, 이용 방법 및 조성물
US20070092452A1 (en) * 2003-07-18 2007-04-26 Julia Rashba-Step Methods for fabrication, uses, compositions of inhalable spherical particles
AU2004258971A1 (en) * 2003-07-22 2005-02-03 Baxter Healthcare S.A. Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
US20060135277A1 (en) * 2003-09-10 2006-06-22 Marnocha Bendict F Golf club and practice arrangement
FR2865938B1 (fr) * 2004-02-05 2006-06-02 Sod Conseils Rech Applic Formulation retard solide comprenant de l'acetate de triptoreline
MXPA06012992A (es) * 2004-05-12 2007-02-12 Baxter Int Microesferas que comprenden proteina y que muestran inyectabilidad en altas concentraciones de este agente.
US8728525B2 (en) * 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
US7884085B2 (en) * 2004-05-12 2011-02-08 Baxter International Inc. Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes
DK2072040T3 (da) 2004-05-12 2013-07-29 Baxter Healthcare Sa Terapeutisk anvendelse af nukleinsyremikrokugler
US20060127486A1 (en) * 2004-07-13 2006-06-15 Moerck Rudi E Ceramic structures for prevention of drug diversion
WO2006017337A1 (en) * 2004-07-13 2006-02-16 Altairnano, Inc. Ceramic structures for controlled release of drugs
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CN101188996B (zh) * 2005-04-27 2013-03-27 巴克斯特国际公司 表面改性的微粒及其形成和使用方法
AU2006283170A1 (en) * 2005-08-23 2007-03-01 Altairnano, Inc. Highly photocatalytic phosphorus-doped anatase-TiO2 composition and related manufacturing methods
US20080020175A1 (en) * 2006-03-02 2008-01-24 Fred Ratel Nanostructured Indium-Doped Iron Oxide
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US20080248122A1 (en) * 2006-10-06 2008-10-09 Baxter International Inc. Microencapsules Containing Surface-Modified Microparticles And Methods Of Forming And Using The Same
WO2008043157A1 (en) 2006-10-12 2008-04-17 The University Of Queensland Compositions and methods for modulating immune responses
US20090169628A1 (en) 2006-10-17 2009-07-02 Armark Authentication Technologies, Llc Article and method for focused delivery of therapeutic and/or diagnostic materials
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US8808747B2 (en) * 2007-04-17 2014-08-19 Baxter International Inc. Nucleic acid microparticles for pulmonary delivery
US9782300B2 (en) 2008-02-01 2017-10-10 Kci Licensing, Inc. Fiber-microsphere bioresorbable composite scaffold for wound healing
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US8323685B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
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EP0145240A2 (en) * 1983-11-04 1985-06-19 Takeda Chemical Industries, Ltd. Method for producing Microcapsule

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Also Published As

Publication number Publication date
SE9102249L (sv) 1992-02-02
OA09387A (fr) 1992-09-15
MY107500A (en) 1995-12-30
US5213812A (en) 1993-05-25
IN178446B (cg-RX-API-DMAC7.html) 1997-05-03
DE4125542A1 (de) 1992-02-06
NL194637C (nl) 2002-10-04
CH682715A5 (fr) 1993-11-15
FR2665360B1 (fr) 1995-02-10
NO912986D0 (no) 1991-07-31
AU8146691A (en) 1992-02-06
IE65124B1 (en) 1995-10-04
ES2046083A1 (es) 1994-01-16
MA22245A1 (fr) 1992-04-01
AU649696B2 (en) 1994-06-02
FI104149B (fi) 1999-11-30
SE505734C2 (sv) 1997-10-06
GB9016885D0 (en) 1990-09-12
GR1001512B (el) 1994-02-28
BE1004772A3 (fr) 1993-01-26
NO300158B1 (no) 1997-04-21
CA2048270A1 (en) 1992-02-02
PT98497B (pt) 1997-10-31
ITMI911953A0 (it) 1991-07-15
PT98497A (pt) 1992-06-30
FI913646A0 (fi) 1991-07-31
NL194637B (nl) 2002-06-03
NO912986L (no) 1992-02-03
ZA915565B (en) 1992-04-29
NL9101306A (nl) 1992-03-02
AU5939394A (en) 1994-06-02
AU666808B2 (en) 1996-02-22
JP2818704B2 (ja) 1998-10-30
ITMI911953A1 (it) 1993-01-15
IT1251788B (it) 1995-05-26
JPH05178740A (ja) 1993-07-20
LU87982A1 (fr) 1992-04-15
DK175756B1 (da) 2005-02-14
DK141891A (da) 1992-02-02
SE9102249D0 (sv) 1991-07-26
CA2048270C (en) 1997-02-25
FI104149B1 (fi) 1999-11-30
KR920003962A (ko) 1992-03-27
NZ238981A (en) 1992-11-25
GR910100330A (en) 1992-08-31
HK33294A (en) 1994-04-22
ES2046083B1 (es) 1994-08-01
DK141891D0 (da) 1991-07-31
ATA152591A (de) 1993-01-15
TNSN91067A1 (fr) 1992-10-25
FI913646L (fi) 1992-02-02
IE912700A1 (en) 1992-02-12
FR2665360A1 (fr) 1992-02-07

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