AT388378B - Neue 1-phenylchinazolin-1h,3h-2,4-dione und 1-phenylpyrido(2,3-d)pyrimidin-1h,3h-2,4-dione und sie enthaltende pharmazeutische zusammensetzungen - Google Patents

Neue 1-phenylchinazolin-1h,3h-2,4-dione und 1-phenylpyrido(2,3-d)pyrimidin-1h,3h-2,4-dione und sie enthaltende pharmazeutische zusammensetzungen

Info

Publication number
AT388378B
AT388378B AT0263087A AT263087A AT388378B AT 388378 B AT388378 B AT 388378B AT 0263087 A AT0263087 A AT 0263087A AT 263087 A AT263087 A AT 263087A AT 388378 B AT388378 B AT 388378B
Authority
AT
Austria
Prior art keywords
dione
phenylchinazolin
phenylpyrido
pyrimidin
new
Prior art date
Application number
AT0263087A
Other languages
English (en)
Other versions
ATA263087A (de
Inventor
John Adams Lowe Iii
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ATA263087A publication Critical patent/ATA263087A/de
Application granted granted Critical
Publication of AT388378B publication Critical patent/AT388378B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)
AT0263087A 1986-08-21 1987-10-08 Neue 1-phenylchinazolin-1h,3h-2,4-dione und 1-phenylpyrido(2,3-d)pyrimidin-1h,3h-2,4-dione und sie enthaltende pharmazeutische zusammensetzungen AT388378B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1986/001718 WO1988001270A1 (en) 1986-08-21 1986-08-21 Pyridopyrimidinediones

Publications (2)

Publication Number Publication Date
ATA263087A ATA263087A (de) 1988-11-15
AT388378B true AT388378B (de) 1989-06-12

Family

ID=22195608

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0263087A AT388378B (de) 1986-08-21 1987-10-08 Neue 1-phenylchinazolin-1h,3h-2,4-dione und 1-phenylpyrido(2,3-d)pyrimidin-1h,3h-2,4-dione und sie enthaltende pharmazeutische zusammensetzungen

Country Status (25)

Country Link
US (1) US4797403A (de)
JP (1) JPH0625166B2 (de)
KR (1) KR900003497B1 (de)
CN (1) CN1014992B (de)
AR (1) AR243513A1 (de)
AT (1) AT388378B (de)
AU (1) AU579047B2 (de)
CA (1) CA1294618C (de)
CS (1) CS268189B2 (de)
DD (1) DD261598A5 (de)
DK (1) DK433787A (de)
EG (1) EG18270A (de)
FI (1) FI84720C (de)
HU (1) HU196798B (de)
IE (1) IE59937B1 (de)
IL (1) IL83569A (de)
MX (1) MX7829A (de)
MY (1) MY101821A (de)
NO (1) NO165493C (de)
NZ (1) NZ221502A (de)
PH (1) PH23853A (de)
PT (1) PT85555B (de)
RU (1) RU1769758C (de)
WO (1) WO1988001270A1 (de)
ZA (1) ZA876172B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0260817B1 (de) * 1986-08-21 1991-05-15 Pfizer Inc. Chinazolindione und Pyridopyrimidindione
US5290780A (en) * 1991-01-30 1994-03-01 American Cyanamid Co. Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
NZ322197A (en) * 1995-11-21 1999-02-25 Yamanouchi Pharma Co Ltd Pyrido[2,3-d] pyrimidine derivatives and pharmaceutical compositions thereof
GB0507298D0 (en) * 2005-04-11 2005-05-18 Novartis Ag Organic compounds
SA08280783B1 (ar) * 2007-01-11 2011-04-24 استرازينيكا ايه بي مشتقات بيريدوبيريميدين كمثبطات pde4
FR2943673B1 (fr) * 2009-03-27 2013-03-29 Sanofi Aventis Applications therapeutiques de derives de quinazolinedione
CN103443085B (zh) * 2011-03-14 2016-03-23 南京英派药业有限公司 喹唑啉二酮及其应用
TWI527800B (zh) 2011-04-01 2016-04-01 南京英派藥業有限公司 作為聚(二磷酸腺苷酸-核醣)聚合酶(parp)之抑制劑之1-(芳基甲基)喹唑啉-2,4(1h,3h)-二酮及其應用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1454666A (en) * 1973-10-25 1976-11-03 Hisamitsu Pharmaceutical Co Pyrido 2,3-d- pyrimidinethiones

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH490801A (de) * 1968-02-27 1970-05-31 Ciba Geigy Schädlingsbekämpfungsmittel und dessen Verwendung
US3794643A (en) * 1971-04-20 1974-02-26 Hisamitsu Pharmaceutical Co Quinazolinedione derivatives
DE2334266A1 (de) * 1972-07-07 1974-01-31 Hisamitsu Pharmaceutical Co Pyrido eckige klammer auf 2,3-d eckige klammer zu pyrimidin-2,4 (1h, 3h)-dione
US3922275A (en) * 1972-11-09 1975-11-25 Hisamitsu Pharmaceutical Co Pyrido{8 2,3-D{9 {0 pyrimidine-2,4(1H,3H)-diones
JPS5649917B2 (de) * 1973-12-18 1981-11-25
JPS5849559B2 (ja) * 1974-02-19 1983-11-05 ヒサミツセイヤク カブシキガイシヤ シンキナ ピリドピリミジンジオンユウドウタイノ セイゾウホウ
JPS50116493A (de) * 1974-02-20 1975-09-11
JPS50157393A (de) * 1974-05-24 1975-12-19
JPS5813551B2 (ja) * 1975-03-15 1983-03-14 ヒサミツセイヤク カブシキガイシヤ シンキナピリド ( 4,3−d ) ピリミジンジオンユウドウタイノセイゾウホウ
US4266056A (en) * 1978-04-07 1981-05-05 Zoecon Corporation Phenyl uracils
DK167280B1 (da) * 1985-03-20 1993-10-04 Ciba Geigy Ag 3-aryluracilderivater, fremgangsmaade til fremstilling deraf, ukrudtsbekaempelsesmidler indeholdende disse derivater samt anvendelsen af derivaterne til ukrudtsbekaempelse
GB8524663D0 (en) * 1985-10-07 1985-11-13 Fujisawa Pharmaceutical Co Quinazoline derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1454666A (en) * 1973-10-25 1976-11-03 Hisamitsu Pharmaceutical Co Pyrido 2,3-d- pyrimidinethiones

Also Published As

Publication number Publication date
RU1769758C (en) 1992-10-15
DK433787A (da) 1988-02-22
CA1294618C (en) 1992-01-21
KR880002868A (ko) 1988-05-12
DD261598A5 (de) 1988-11-02
HU196798B (en) 1989-01-30
PH23853A (en) 1989-11-23
NZ221502A (en) 1989-11-28
HUT44786A (en) 1988-04-28
IL83569A (en) 1991-12-15
JPH0625166B2 (ja) 1994-04-06
KR900003497B1 (ko) 1990-05-21
CS597487A2 (en) 1989-05-12
FI873608A0 (fi) 1987-08-20
PT85555B (pt) 1990-05-31
NO873514L (no) 1988-02-22
PT85555A (en) 1987-09-01
ZA876172B (en) 1989-03-29
EG18270A (en) 1992-12-30
NO165493C (no) 1991-02-20
AU7724787A (en) 1988-03-10
CS268189B2 (en) 1990-03-14
US4797403A (en) 1989-01-10
JPS6360974A (ja) 1988-03-17
NO165493B (no) 1990-11-12
FI84720B (fi) 1991-09-30
DK433787D0 (da) 1987-08-20
MY101821A (en) 1992-01-31
FI84720C (fi) 1992-01-10
CN87105791A (zh) 1988-03-09
ATA263087A (de) 1988-11-15
FI873608A (fi) 1988-02-22
IE59937B1 (en) 1994-05-04
WO1988001270A1 (en) 1988-02-25
CN1014992B (zh) 1991-12-04
IE872239L (en) 1989-01-20
AU579047B2 (en) 1988-11-10
MX7829A (es) 1993-08-01
IL83569A0 (en) 1988-01-31
AR243513A1 (es) 1993-08-31
NO873514D0 (no) 1987-08-20

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