AT381492B - Verfahren zur herstellung von neuen als antihyper-tensiva verwendbaren 1-phenoxy-3-hydroxyindolylalkylamino-3-propanolverbindungen - Google Patents

Verfahren zur herstellung von neuen als antihyper-tensiva verwendbaren 1-phenoxy-3-hydroxyindolylalkylamino-3-propanolverbindungen

Info

Publication number
AT381492B
AT381492B AT0186784A AT186784A AT381492B AT 381492 B AT381492 B AT 381492B AT 0186784 A AT0186784 A AT 0186784A AT 186784 A AT186784 A AT 186784A AT 381492 B AT381492 B AT 381492B
Authority
AT
Austria
Prior art keywords
tensiva
hydroxyindolylalkylamino
ani
hyper
phenoxy
Prior art date
Application number
AT0186784A
Other languages
German (de)
English (en)
Other versions
ATA186784A (de
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ATA186784A publication Critical patent/ATA186784A/de
Application granted granted Critical
Publication of AT381492B publication Critical patent/AT381492B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0186784A 1983-06-10 1984-06-06 Verfahren zur herstellung von neuen als antihyper-tensiva verwendbaren 1-phenoxy-3-hydroxyindolylalkylamino-3-propanolverbindungen AT381492B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50290183A 1983-06-10 1983-06-10

Publications (2)

Publication Number Publication Date
ATA186784A ATA186784A (de) 1986-03-15
AT381492B true AT381492B (de) 1986-10-27

Family

ID=23999880

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0186784A AT381492B (de) 1983-06-10 1984-06-06 Verfahren zur herstellung von neuen als antihyper-tensiva verwendbaren 1-phenoxy-3-hydroxyindolylalkylamino-3-propanolverbindungen

Country Status (29)

Country Link
JP (1) JPS608262A (nl)
KR (1) KR900005021B1 (nl)
AT (1) AT381492B (nl)
AU (1) AU569303B2 (nl)
BE (1) BE899875A (nl)
CA (1) CA1217496A (nl)
CH (1) CH662561A5 (nl)
CY (1) CY1518A (nl)
DE (1) DE3421252A1 (nl)
DK (1) DK162089C (nl)
ES (1) ES8507490A1 (nl)
FI (1) FI78291C (nl)
FR (1) FR2549054B1 (nl)
GB (1) GB2141121B (nl)
GR (1) GR82208B (nl)
HK (1) HK14690A (nl)
HU (1) HU191670B (nl)
IE (1) IE57682B1 (nl)
IL (1) IL72008A (nl)
IT (1) IT1206705B (nl)
LU (1) LU85410A1 (nl)
MY (1) MY102077A (nl)
NL (1) NL8401840A (nl)
NO (1) NO164471C (nl)
NZ (1) NZ208337A (nl)
SE (1) SE455865B (nl)
SG (1) SG1090G (nl)
YU (1) YU44873B (nl)
ZA (1) ZA844277B (nl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
KR101986648B1 (ko) 2018-04-06 2019-06-07 (유)로뎀건설 강관작업구 굴착장치

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3337628A (en) * 1962-11-23 1967-08-22 Ici Ltd 3-naphthyloxy-2-hydroxypropylamines
US4234595A (en) * 1977-07-13 1980-11-18 Mead Johnson & Company 3-Indolyl-tertiary butylaminopropanols
US4314943A (en) * 1977-07-13 1982-02-09 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB962793A (en) * 1959-07-13 1964-07-01 Philips Nv Improvements in or relating to pharmacologically active compounds being substituted tryptamines
CA1116598A (en) * 1977-07-13 1982-01-19 William T. Comer 3-indolyl-tertiary butylaminopropanols
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3337628A (en) * 1962-11-23 1967-08-22 Ici Ltd 3-naphthyloxy-2-hydroxypropylamines
US4234595A (en) * 1977-07-13 1980-11-18 Mead Johnson & Company 3-Indolyl-tertiary butylaminopropanols
US4314943A (en) * 1977-07-13 1982-02-09 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols

Also Published As

Publication number Publication date
YU44873B (en) 1991-04-30
SG1090G (en) 1990-07-06
SE455865B (sv) 1988-08-15
YU99784A (en) 1986-10-31
GB2141121A (en) 1984-12-12
FR2549054A1 (fr) 1985-01-18
GB2141121B (en) 1987-01-07
SE8403112D0 (sv) 1984-06-08
KR900005021B1 (ko) 1990-07-18
IE57682B1 (en) 1993-02-24
HUT34445A (en) 1985-03-28
SE8403112L (sv) 1984-12-11
LU85410A1 (fr) 1985-03-26
DK284184A (da) 1984-12-11
HU191670B (en) 1987-03-30
HK14690A (en) 1990-03-02
CH662561A5 (de) 1987-10-15
FI842316A0 (fi) 1984-06-07
FI78291B (fi) 1989-03-31
MY102077A (en) 1992-03-31
DK284184D0 (da) 1984-06-08
ATA186784A (de) 1986-03-15
NO164471B (no) 1990-07-02
JPH0587503B2 (nl) 1993-12-16
NO164471C (no) 1990-10-10
NL8401840A (nl) 1985-01-02
IT1206705B (it) 1989-04-27
IE841441L (en) 1984-12-10
DE3421252A1 (de) 1984-12-13
NO842279L (no) 1984-12-11
KR850000396A (ko) 1985-02-27
FI78291C (fi) 1989-07-10
ZA844277B (en) 1985-03-27
IL72008A (en) 1988-05-31
ES533185A0 (es) 1985-09-16
CY1518A (en) 1990-11-16
DK162089B (da) 1991-09-16
DK162089C (da) 1992-02-24
ES8507490A1 (es) 1985-09-16
GR82208B (nl) 1984-12-13
IT8421330A0 (it) 1984-06-08
NZ208337A (en) 1988-10-28
AU2923884A (en) 1984-12-13
CA1217496A (en) 1987-02-03
JPS608262A (ja) 1985-01-17
AU569303B2 (en) 1988-01-28
IL72008A0 (en) 1984-10-31
FI842316A (fi) 1984-12-11
GB8414652D0 (en) 1984-07-11
FR2549054B1 (fr) 1988-03-04
BE899875A (fr) 1984-12-10

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee