AT353795B - Verfahren zur herstellung des neuen 6-chlor-2- (1'-piperazinyl)-pyrazins, seiner n-oxide und seiner salze - Google Patents
Verfahren zur herstellung des neuen 6-chlor-2- (1'-piperazinyl)-pyrazins, seiner n-oxide und seiner salzeInfo
- Publication number
- AT353795B AT353795B AT288376A AT288376A AT353795B AT 353795 B AT353795 B AT 353795B AT 288376 A AT288376 A AT 288376A AT 288376 A AT288376 A AT 288376A AT 353795 B AT353795 B AT 353795B
- Authority
- AT
- Austria
- Prior art keywords
- pyrazine
- piperazinyl
- chlorine
- oxides
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57005275A | 1975-04-21 | 1975-04-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA288376A ATA288376A (de) | 1979-05-15 |
| AT353795B true AT353795B (de) | 1979-12-10 |
Family
ID=24277994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT288376A AT353795B (de) | 1975-04-21 | 1976-04-20 | Verfahren zur herstellung des neuen 6-chlor-2- (1'-piperazinyl)-pyrazins, seiner n-oxide und seiner salze |
Country Status (36)
| Country | Link |
|---|---|
| JP (1) | JPS51136688A (nl) |
| AR (1) | AR210349A1 (nl) |
| AT (1) | AT353795B (nl) |
| AU (1) | AU496854B2 (nl) |
| BE (1) | BE840904A (nl) |
| BG (1) | BG34185A3 (nl) |
| CA (1) | CA1059128A (nl) |
| CH (1) | CH619462A5 (nl) |
| CS (1) | CS195726B2 (nl) |
| CY (1) | CY1090A (nl) |
| DD (1) | DD124599A5 (nl) |
| DE (1) | DE2617205C3 (nl) |
| DK (1) | DK143899C (nl) |
| EG (1) | EG12387A (nl) |
| ES (4) | ES447150A1 (nl) |
| FI (1) | FI62666C (nl) |
| FR (1) | FR2308367A1 (nl) |
| GB (1) | GB1492528A (nl) |
| GR (1) | GR59900B (nl) |
| HK (1) | HK60380A (nl) |
| HU (1) | HU172684B (nl) |
| IE (1) | IE42979B1 (nl) |
| IL (1) | IL49391A (nl) |
| KE (1) | KE3088A (nl) |
| LU (1) | LU74795A1 (nl) |
| MY (1) | MY8100225A (nl) |
| NL (1) | NL167692C (nl) |
| NO (1) | NO146599C (nl) |
| PH (1) | PH12274A (nl) |
| PL (1) | PL99664B1 (nl) |
| PT (1) | PT65027B (nl) |
| RO (1) | RO73278A (nl) |
| SE (1) | SE421695B (nl) |
| SU (1) | SU638260A3 (nl) |
| YU (1) | YU100676A (nl) |
| ZA (1) | ZA762320B (nl) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091098A (en) * | 1977-04-25 | 1978-05-23 | Merck & Co., Inc. | 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides |
| US4163849A (en) | 1978-03-17 | 1979-08-07 | Merck & Co., Inc. | Piperazinylpyrazines |
| US4252816A (en) * | 1979-12-03 | 1981-02-24 | Merck & Co., Inc. | Tetrahydro-1H-1,4-diazepino(1,7-a)benzimidazoles useful as analgesic agents |
| US4339579A (en) | 1980-12-29 | 1982-07-13 | American Home Products Corporation | 2,6-Bis-(pyrrolopyrazinyl)pyrazines |
| EP0094498A3 (en) * | 1982-05-06 | 1985-04-03 | American Cyanamid Company | Antiatherosclerotic 1-piperazine derivatives |
| US4547505A (en) * | 1983-03-25 | 1985-10-15 | Degussa Aktiengesellschaft | N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production |
| US4788290A (en) * | 1987-12-11 | 1988-11-29 | American Home Products Corporation | Serotonergic pyrazine derivatives |
| EP0580465A1 (fr) * | 1992-06-25 | 1994-01-26 | Sanofi | Nouvelle utilisation thérapeutique d'hétérocyclyl-pipérazines comme 5-HT3 agonistes et nouveaux dérivés |
| ATE491689T1 (de) * | 1997-10-27 | 2011-01-15 | Neurosearch As | Heteroaryl diazacycloalkane als cholinergische ligande für nikotin-acetylcholin-rezeptoren |
| AU773830B2 (en) * | 1999-04-26 | 2004-06-10 | Neurosearch A/S | Heteroaryl diazacycloalkanes, their preparation and use |
| KR20030031886A (ko) * | 2000-02-16 | 2003-04-23 | 뉴로젠 코포레이션 | 치환된 아릴피라진 |
| US6825198B2 (en) * | 2001-06-21 | 2004-11-30 | Pfizer Inc | 5-HT receptor ligands and uses thereof |
| SE0202287D0 (sv) * | 2002-07-19 | 2002-07-19 | Biovitrum Ab | New compounds |
| ATE353693T1 (de) | 2002-07-19 | 2007-03-15 | Biovitrum Ab | Neue piperazinyl-pyrazinon-derivate zur behandlung von 5-ht2a rezeptor-bedingten erkrankungen |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2606906A (en) * | 1948-10-14 | 1952-08-12 | American Cyanamid Co | 1-(2-pyridyl) piperazine and process of preparing same |
-
1976
- 1976-04-07 EG EG76205A patent/EG12387A/xx active
- 1976-04-07 SE SE7604093A patent/SE421695B/xx not_active IP Right Cessation
- 1976-04-07 DK DK164476A patent/DK143899C/da not_active IP Right Cessation
- 1976-04-08 NO NO761207A patent/NO146599C/no unknown
- 1976-04-09 NL NL7603800A patent/NL167692C/nl not_active IP Right Cessation
- 1976-04-09 FI FI760978A patent/FI62666C/fi not_active IP Right Cessation
- 1976-04-12 IL IL49391A patent/IL49391A/xx unknown
- 1976-04-13 AU AU12966/76A patent/AU496854B2/en not_active Expired
- 1976-04-13 PH PH18329A patent/PH12274A/en unknown
- 1976-04-13 GR GR50538A patent/GR59900B/el unknown
- 1976-04-14 CA CA250,732A patent/CA1059128A/en not_active Expired
- 1976-04-14 FR FR7610958A patent/FR2308367A1/fr active Granted
- 1976-04-15 DD DD192399A patent/DD124599A5/xx unknown
- 1976-04-15 CY CY1090A patent/CY1090A/xx unknown
- 1976-04-15 GB GB15644/76A patent/GB1492528A/en not_active Expired
- 1976-04-16 CS CS762549A patent/CS195726B2/cs unknown
- 1976-04-19 JP JP51043763A patent/JPS51136688A/ja active Granted
- 1976-04-19 ES ES447150A patent/ES447150A1/es not_active Expired
- 1976-04-20 YU YU01006/76A patent/YU100676A/xx unknown
- 1976-04-20 AT AT288376A patent/AT353795B/de not_active IP Right Cessation
- 1976-04-20 BG BG032968A patent/BG34185A3/xx unknown
- 1976-04-20 PL PL1976188912A patent/PL99664B1/pl unknown
- 1976-04-20 RO RO7685688A patent/RO73278A/ro unknown
- 1976-04-20 SU SU762346054A patent/SU638260A3/ru active
- 1976-04-20 CH CH492676A patent/CH619462A5/de not_active IP Right Cessation
- 1976-04-20 ZA ZA762320A patent/ZA762320B/xx unknown
- 1976-04-20 AR AR262930A patent/AR210349A1/es active
- 1976-04-20 LU LU74795A patent/LU74795A1/xx unknown
- 1976-04-20 BE BE166282A patent/BE840904A/xx not_active IP Right Cessation
- 1976-04-20 DE DE2617205A patent/DE2617205C3/de not_active Expired
- 1976-04-21 HU HU76ME00001967A patent/HU172684B/hu unknown
- 1976-04-21 IE IE828/76A patent/IE42979B1/en unknown
- 1976-04-21 PT PT65027A patent/PT65027B/pt unknown
-
1977
- 1977-06-01 ES ES459406A patent/ES459406A1/es not_active Expired
- 1977-06-01 ES ES459405A patent/ES459405A1/es not_active Expired
- 1977-06-01 ES ES459407A patent/ES459407A1/es not_active Expired
-
1980
- 1980-10-02 KE KE3088A patent/KE3088A/xx unknown
- 1980-10-30 HK HK603/80A patent/HK60380A/xx unknown
-
1981
- 1981-12-30 MY MY225/81A patent/MY8100225A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATA800876A (de) | Verfahren zur herstellung von neuen 2-phenyl-3- aroylbenzothiophenen und 2-phenyl-3- -aroylbenzothiophen-1-oxiden und von deren salzen | |
| AT361912B (de) | Verfahren zur herstellung von neuen heterocyclischen 1-aryloxy-2-hydroxy-3- alkylenaminopropanen und deren salzen | |
| AT363491B (de) | Verfahren zur herstellung von neuen 1,3,8trisubstituierten xanthinen und deren salzen | |
| AT353795B (de) | Verfahren zur herstellung des neuen 6-chlor-2- (1'-piperazinyl)-pyrazins, seiner n-oxide und seiner salze | |
| AT360034B (de) | Verfahren zur herstellung von neuen substi- tuierten 6-phenyl-1,2,4-triazolo-(4,3-b)pyri- dazinen und deren salzen | |
| AT359064B (de) | Verfahren zur herstellung von neuen 1h- -pyrazolo (3,4-b)-pyridinen und deren saeure- additionssalzen | |
| AT347952B (de) | Verfahren zur herstellung von neuen 1,1,1- triarylalkylaminen und deren salzen | |
| AT355018B (de) | Verfahren zur herstellung von neuen 1,2- benzisothiazolinonen und von deren salzen | |
| ATA43078A (de) | Verfahren zur herstellung von neuen imidazo- (1,2-a)-chinolin-derivaten und ihren salzen | |
| AT345846B (de) | Verfahren zur herstellung des neuen 4-imino- 1.3-diazabicyclo- (3.1.0)-hexan-2-on und seiner physiologisch vertraeglichen salze | |
| AT378958B (de) | Verfahren zur herstellung von neuen derivaten des 1,4-chinolyl-2-(4-piperidyl)-aethanols oder des 1,4-chinolyl-3-(4-piperidyl)-propanols und deren salzen | |
| AT351025B (de) | Verfahren zur herstellung von neuen 1,4-dihydro -pyridinen und deren salzen | |
| AT342034B (de) | Verfahren zur herstellung von neuen 4,4-diphenyl-2-hydroxybutylaminen und ihren salzen | |
| AT357144B (de) | Verfahren zur herstellung von neuen 1-acyl-2- hydroxy-1,3-diaminopropanen und deren salzen | |
| AT359070B (de) | Verfahren zur herstellung von neuen 2,4-diamino -5-benzylpyrimidinen und deren salzen | |
| AT344886B (de) | Verfahren zur herstellung des neuen fortimicin c und seiner salze | |
| AT358588B (de) | Verfahren zur herstellung von neuen 1,2,3,4- -tetrahydroisochinolinen und deren salzen | |
| AT350575B (de) | Verfahren zur herstellung des neuen 1- (4- fluor-3-triflourmethylthio-phenyl)-piperazin und seiner saeureadditionssalze | |
| AT353274B (de) | Verfahren zur herstellung von 2-substituierten 1,4-benzodiazepinen und deren saeureadditions- verbindungen | |
| AT349482B (de) | Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxiden und salzen | |
| ATA670977A (de) | Verfahren zur herstellung des neuen n-6-chlor- nicothinoyl-d,1-homocysteinthiolactons und dessen salzen | |
| AT363476B (de) | Verfahren zur herstellung von neuen 5,6-dihydro-imidazo(5,1-a)isochinolin-derivaten und ihren salzen | |
| AT357148B (de) | Verfahren zur herstellung von neuen 2,3-dihydro -2-oxo-thiophenderivaten und ihren salzen | |
| AT356654B (de) | Verfahren zur herstellung von substituierten 6- -aryl-4h-s-triazolo-(3,4-c)-thieno-(2,3-e)-1,4- -diazepinen und deren salzen | |
| AT356293B (de) | Verfahren zur herstellung von neuen d-6-alkyl-8 -zyanmethylergolinen-i und deren salzen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee | ||
| ELA | Expired due to lapse of time |